| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NG25 perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the NG25_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PCBP2 | poly(rC) binding protein 2 | 0.140384 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.10299 |
| MCL1 | myeloid cell leukemia 1 | 0.0940874 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0898366 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0707926 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0691186 |
| LDHA | lactate dehydrogenase A | 0.0660973 |
| RPL3 | ribosomal protein L3 | 0.0631275 |
| GRAMD1B | GRAM domain containing 1B | 0.0616762 |
| RPS18 | ribosomal protein S18 | 0.0605774 |
| TPM3 | tropomyosin 3 | 0.058702 |
| KYNU | kynureninase | 0.0545522 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0532946 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0479556 |
| ASPH | aspartate beta-hydroxylase | 0.047691 |
| PKM | pyruvate kinase, muscle | 0.0476766 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0474407 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.047064 |
| POTEF | POTE ankyrin domain family, member F | 0.0455674 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0423531 |
| KRT19 | keratin 19, type I | 0.041662 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0409987 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0401628 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0400763 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0378078 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0373742 |
| RPS4X | ribosomal protein S4, X-linked | 0.0369667 |
| RPS12 | ribosomal protein S12 | 0.0366026 |
| RAD51B | RAD51 paralog B | 0.0359138 |
| RPS2 | ribosomal protein S2 | 0.0353416 |
| EZR | ezrin | 0.0350031 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0340941 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0340158 |
| ENO1 | enolase 1, (alpha) | 0.0339052 |
| CD109 | CD109 molecule | 0.0338483 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0330366 |
| MT2A | metallothionein 2A | 0.032631 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0325056 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0322918 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.030087 |
| MSN | moesin | 0.0299433 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0291953 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0287365 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0287296 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0281892 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0279276 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.027809 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0275274 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0272067 |
| EFNA5 | ephrin-A5 | 0.0265954 |
| SET | SET nuclear proto-oncogene | 0.0260944 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0258722 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0257636 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0253102 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0251833 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0250174 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0250135 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0248067 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0245105 |
| YBX1 | Y box binding protein 1 | 0.0241828 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0238616 |
| RPL21 | ribosomal protein L21 | 0.0234695 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0233745 |
| FAT1 | FAT atypical cadherin 1 | 0.0231454 |
| PYGL | phosphorylase, glycogen, liver | 0.0230951 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0228124 |
| RPS7 | ribosomal protein S7 | 0.0222769 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0221977 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.02189 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0218632 |
| HLA-A | major histocompatibility complex, class I, A | 0.0217011 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0216188 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0214639 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0209955 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0209417 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0209122 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0208105 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.020738 |
| SQSTM1 | sequestosome 1 | 0.0207327 |
| APP | amyloid beta (A4) precursor protein | 0.020374 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0203415 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0202433 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0202242 |
| NCAM1 | neural cell adhesion molecule 1 | 0.0200819 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0199862 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0198155 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0195895 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0192727 |
| NONO | non-POU domain containing, octamer-binding | 0.0190203 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0189913 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0186138 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0184508 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0182774 |
| FMNL2 | formin-like 2 | 0.0181793 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0178343 |
| FLNA | filamin A, alpha | 0.0177745 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0177689 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | 0.0177652 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0176558 |
| HYOU1 | hypoxia up-regulated 1 | 0.0172899 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.247903 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.2314 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.180338 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.11806 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.117888 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.112136 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0957674 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0839406 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0771011 |
| TMSB10 | thymosin beta 10 | -0.0765345 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0746997 |
| RPS24 | ribosomal protein S24 | -0.0712318 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0707117 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0683756 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.068287 |
| PTMA | prothymosin, alpha | -0.0669335 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.060117 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0594679 |
| HLA-B | major histocompatibility complex, class I, B | -0.0581108 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.057975 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0536118 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0504938 |
| SMYD3 | SET and MYND domain containing 3 | -0.0503128 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0494155 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0454713 |
| RPL35A | ribosomal protein L35a | -0.0448811 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0425086 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0418609 |
| RPLP1 | ribosomal protein, large, P1 | -0.0418122 |
| CANX | calnexin | -0.0410291 |
| VCL | vinculin | -0.0405761 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0394318 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.038952 |
| STC1 | stanniocalcin 1 | -0.037098 |
| RPL34 | ribosomal protein L34 | -0.0361502 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0351602 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0339874 |
| OGA | O-GlcNAcase | -0.0333229 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0329118 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0328666 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.032837 |
| RPS21 | ribosomal protein S21 | -0.0327936 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.032532 |
| RPL7A | ribosomal protein L7a | -0.0323049 |
| RPL38 | ribosomal protein L38 | -0.0313499 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0311847 |
| PCBP3 | poly(rC) binding protein 3 | -0.0310147 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0308436 |
| RPL19 | ribosomal protein L19 | -0.0304362 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0300861 |
| NCKAP5 | NCK-associated protein 5 | -0.029859 |
| S100A6 | S100 calcium binding protein A6 | -0.0297081 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.029468 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0294326 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0292587 |
| ACTG1 | actin gamma 1 | -0.0279443 |
| CDH13 | cadherin 13 | -0.027873 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0275751 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0274908 |
| FOXC1 | forkhead box C1 | -0.0274176 |
| PTGR1 | prostaglandin reductase 1 | -0.0272153 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0271648 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0270587 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0270326 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0267863 |
| JMJD1C | jumonji domain containing 1C | -0.0264271 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.025968 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0258697 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0257191 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0256835 |
| COL5A2 | collagen, type V, alpha 2 | -0.025593 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0251871 |
| ATAD1 | ATPase family, AAA domain containing 1 | -0.0251857 |
| TMSB4X | thymosin beta 4, X-linked | -0.0251617 |
| GNAS | GNAS complex locus | -0.0251579 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0251193 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0248014 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0246599 |
| SLC16A6 | solute carrier family 16, member 6 | -0.0246209 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0244753 |
| KIAA0825 | KIAA0825 | -0.0244546 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0237346 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0236315 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0235275 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0231852 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.022933 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0221356 |
| RPS16 | ribosomal protein S16 | -0.0218622 |
| PCNX4 | pecanex 4 | -0.0218083 |
| STEAP1B | STEAP family member 1B | -0.021728 |
| RPS27A | ribosomal protein S27a | -0.0217058 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0216633 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0213811 |
| MAP4 | microtubule-associated protein 4 | -0.0212057 |
| RPL6 | ribosomal protein L6 | -0.0210431 |
| INHBA | inhibin, beta A | -0.0209849 |
| RPL36A | ribosomal protein L36a | -0.0209383 |
| RBM39 | RNA binding motif protein 39 | -0.0209331 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0209157 |
| RPS25 | ribosomal protein S25 | -0.0208645 |
