| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NG25 perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
111 genes differentially expressed following the NG25_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.202843 |
| FNDC3B | fibronectin type III domain containing 3B | 0.154476 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.121162 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.114329 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.102111 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.101619 |
| PTK2 | protein tyrosine kinase 2 | 0.0980645 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0962414 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0924911 |
| FRMD4A | FERM domain containing 4A | 0.0910822 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0878498 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0877829 |
| RPLP2 | ribosomal protein, large, P2 | 0.0859909 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0842935 |
| PGK1 | phosphoglycerate kinase 1 | 0.0803157 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0757608 |
| MT2A | metallothionein 2A | 0.0756238 |
| PKM | pyruvate kinase, muscle | 0.0750214 |
| RPLP1 | ribosomal protein, large, P1 | 0.0607546 |
| FMN1 | formin 1 | 0.0593875 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0588043 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0565777 |
| SBF2 | SET binding factor 2 | 0.0555016 |
| ENO1 | enolase 1, (alpha) | 0.055092 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0502992 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0491016 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0472815 |
| PTMA | prothymosin, alpha | 0.0467253 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0462941 |
| RPS12 | ribosomal protein S12 | 0.0437318 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.043577 |
| DST | dystonin | 0.0432974 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0429308 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0401945 |
| NDRG1 | N-myc downstream regulated 1 | 0.0393891 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0383634 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.036758 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0363876 |
| EGFR | epidermal growth factor receptor | 0.0355633 |
| RPL31 | ribosomal protein L31 | 0.0341831 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0334615 |
| MYO1E | myosin IE | 0.0333982 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0288412 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0273975 |
| EZR | ezrin | 0.0257638 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0226259 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0204243 |
| SPAG9 | sperm associated antigen 9 | 0.0201642 |
| LDHA | lactate dehydrogenase A | 0.0173268 |
| NHSL1 | NHS-like 1 | 0.0171562 |
| FTL | ferritin, light polypeptide | 0.0148647 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.00991532 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.00935271 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.00859946 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.00701954 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0065168 |
| ATXN1 | ataxin 1 | 0.00386664 |
| LMO7 | LIM domain 7 | 0.00237134 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.364249 |
| EFNA5 | ephrin-A5 | -0.16302 |
| RORA | RAR-related orphan receptor A | -0.138922 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.134373 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.130288 |
| PDE10A | phosphodiesterase 10A | -0.128674 |
| VCL | vinculin | -0.119623 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.116537 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.106703 |
| GPC6 | glypican 6 | -0.105876 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0955428 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0952321 |
| ASPH | aspartate beta-hydroxylase | -0.0902817 |
| FN1 | fibronectin 1 | -0.0793169 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0756894 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0706929 |
| CDH13 | cadherin 13 | -0.0703329 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0681895 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0678494 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.066559 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0618267 |
| VIM | vimentin | -0.0559504 |
| PRKCA | protein kinase C, alpha | -0.0556457 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.055223 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.052983 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0495662 |
| OGA | O-GlcNAcase | -0.0449983 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0408085 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0371222 |
| SMYD3 | SET and MYND domain containing 3 | -0.0365808 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0351391 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0348379 |
| MYOF | myoferlin | -0.0332953 |
| TBC1D22A | TBC1 domain family, member 22A | -0.030541 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0281914 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0281589 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.028157 |
| SETD5 | SET domain containing 5 | -0.0235444 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0186439 |
| RPS3 | ribosomal protein S3 | -0.0185946 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0185864 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0155088 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0143176 |
| NPAS2 | neuronal PAS domain protein 2 | -0.012734 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0122662 |
| RAD51B | RAD51 paralog B | -0.0110062 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.00872252 |
| PARD3 | par-3 family cell polarity regulator | -0.00857424 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.00789831 |
| RPS6 | ribosomal protein S6 | -0.0057749 |
| TMSB10 | thymosin beta 10 | -0.00317553 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -5.28811E-4 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -9.59419E-5 |
