| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NG25 perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the NG25_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0615823 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.045875 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0399946 |
| COL3A1 | collagen, type III, alpha 1 | 0.0384587 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0383372 |
| HDAC9 | histone deacetylase 9 | 0.0355338 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 0.0317989 |
| PCBP2 | poly(rC) binding protein 2 | 0.031479 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0302955 |
| PCDH9 | protocadherin 9 | 0.0298106 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0298092 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0295078 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0292422 |
| PCDH18 | protocadherin 18 | 0.0289178 |
| FOXG1 | forkhead box G1 | 0.027724 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0268028 |
| PRKD1 | protein kinase D1 | 0.0263546 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0260135 |
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.0256398 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0242856 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.023052 |
| ITSN2 | intersectin 2 | 0.0229382 |
| NDRG1 | N-myc downstream regulated 1 | 0.0227685 |
| CEP350 | centrosomal protein 350kDa | 0.0219421 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0218476 |
| LDHA | lactate dehydrogenase A | 0.0214862 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0210593 |
| UBN2 | ubinuclein 2 | 0.0209674 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0208311 |
| APP | amyloid beta (A4) precursor protein | 0.0205167 |
| SETD5 | SET domain containing 5 | 0.020447 |
| YAP1 | Yes-associated protein 1 | 0.0203505 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.020313 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.02019 |
| LMO7 | LIM domain 7 | 0.020097 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0196762 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0193813 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0193297 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.0191428 |
| MCL1 | myeloid cell leukemia 1 | 0.0190834 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0190724 |
| FN1 | fibronectin 1 | 0.0188114 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0187986 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0187795 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0187519 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0186069 |
| RPS18 | ribosomal protein S18 | 0.018344 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0179441 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0176972 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0176712 |
| TGFB2 | transforming growth factor, beta 2 | 0.0173212 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0171315 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0167266 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0166969 |
| AEBP2 | AE binding protein 2 | 0.0166247 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0164783 |
| PHF3 | PHD finger protein 3 | 0.0164175 |
| RPL3 | ribosomal protein L3 | 0.0163194 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.016214 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.016167 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0160179 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0158347 |
| MYO1E | myosin IE | 0.0157916 |
| COL11A1 | collagen, type XI, alpha 1 | 0.015754 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0156208 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0155731 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.015353 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0153226 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0153156 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0152717 |
| ATXN2 | ataxin 2 | 0.0152661 |
| SSH2 | slingshot protein phosphatase 2 | 0.0152561 |
| DENND5A | DENN/MADD domain containing 5A | 0.0151206 |
| ZNF638 | zinc finger protein 638 | 0.014967 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0148951 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0148376 |
| ARCN1 | archain 1 | 0.0147465 |
| EZR | ezrin | 0.0146361 |
| PGK1 | phosphoglycerate kinase 1 | 0.0146175 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0145572 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0145033 |
| KIF1B | kinesin family member 1B | 0.0144379 |
| UGGT1 | UDP-glucose glycoprotein glucosyltransferase 1 | 0.0144332 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0143609 |
| ERBIN | erbb2 interacting protein | 0.0142668 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.0141673 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0141073 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0140214 |
| SKIL | SKI-like proto-oncogene | 0.0140152 |
| EFNA5 | ephrin-A5 | 0.0138955 |
| COG6 | component of oligomeric golgi complex 6 | 0.0138555 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0138308 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0137547 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0136564 |
| CNOT6 | CCR4-NOT transcription complex, subunit 6 | 0.0136426 |
| STC1 | stanniocalcin 1 | 0.0136307 |
| H1-0 | H1.0 linker histone | 0.0136231 |
| NBAS | neuroblastoma amplified sequence | 0.0135535 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0135525 |
| ENO1 | enolase 1, (alpha) | 0.0135199 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.153431 |
| CADM2 | cell adhesion molecule 2 | -0.120684 |
| VIM | vimentin | -0.119858 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0957985 |
| TMSB10 | thymosin beta 10 | -0.092413 |
| PEG10 | paternally expressed 10 | -0.0828677 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0755334 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.070464 |
| RPS16 | ribosomal protein S16 | -0.0624951 |
| GPC3 | glypican 3 | -0.0585166 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0570798 |
| DST | dystonin | -0.0547231 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0538871 |
| CENPF | centromere protein F, 350/400kDa | -0.0533144 |
| PTMA | prothymosin, alpha | -0.0528445 |
| RPLP1 | ribosomal protein, large, P1 | -0.0522411 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0504921 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0501979 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0501969 |
| RPL35A | ribosomal protein L35a | -0.0489065 |
| RPS6 | ribosomal protein S6 | -0.0481638 |
| ZNF292 | zinc finger protein 292 | -0.0478437 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0462943 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0461996 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.045869 |
| ACTG1 | actin gamma 1 | -0.0450072 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0442088 |
| RPS8 | ribosomal protein S8 | -0.0437189 |
| MAP4 | microtubule-associated protein 4 | -0.0419186 |
| RPL11 | ribosomal protein L11 | -0.0406251 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0404429 |
| MEIS2 | Meis homeobox 2 | -0.0401739 |
| TMSB4X | thymosin beta 4, X-linked | -0.0397648 |
| RPL23 | ribosomal protein L23 | -0.0378713 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0375766 |
| EMP1 | epithelial membrane protein 1 | -0.0373607 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0370387 |
| ENAH | enabled homolog (Drosophila) | -0.0367478 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0364415 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0363514 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0353925 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0347701 |
| ACTN4 | actinin, alpha 4 | -0.0340822 |
| TENM3 | teneurin transmembrane protein 3 | -0.0335229 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0332291 |
| COL1A2 | collagen, type I, alpha 2 | -0.0328373 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0327429 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0325928 |
| DEK | DEK proto-oncogene | -0.0320538 |
| RPL19 | ribosomal protein L19 | -0.0318942 |
| SHROOM3 | shroom family member 3 | -0.0318547 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0312855 |
| RPL12 | ribosomal protein L12 | -0.0312087 |
| RAI1 | retinoic acid induced 1 | -0.0309229 |
| METAP2 | methionyl aminopeptidase 2 | -0.0306757 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0305155 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.03051 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0289054 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0287542 |
| RPL36A | ribosomal protein L36a | -0.028473 |
| PFN1 | profilin 1 | -0.0284299 |
| RPL5 | ribosomal protein L5 | -0.0283393 |
| CBX3 | chromobox homolog 3 | -0.0282032 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0280199 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0279278 |
| RBM39 | RNA binding motif protein 39 | -0.0277067 |
| SYT1 | synaptotagmin I | -0.0276094 |
| ZFR | zinc finger RNA binding protein | -0.0272861 |
| CAVIN1 | caveolae associated protein 1 | -0.0272854 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0271467 |
| SPAG9 | sperm associated antigen 9 | -0.0270522 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | -0.0270447 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0270298 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0269803 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0268888 |
| TPX2 | TPX2, microtubule-associated | -0.0267957 |
| UPP1 | uridine phosphorylase 1 | -0.026527 |
| MKI67 | marker of proliferation Ki-67 | -0.0261657 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.025909 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0257655 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0255477 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0253466 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0253333 |
| TPR | translocated promoter region, nuclear basket protein | -0.0250619 |
| KIF4A | kinesin family member 4A | -0.0249678 |
| FAM171B | family with sequence similarity 171, member B | -0.0248922 |
| SMYD3 | SET and MYND domain containing 3 | -0.0248699 |
| RHEB | Ras homolog enriched in brain | -0.0247124 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0246851 |
| RDX | radixin | -0.0246178 |
| CDK6 | cyclin-dependent kinase 6 | -0.024574 |
| S100A10 | S100 calcium binding protein A10 | -0.0245672 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.024549 |
| PLPP1 | phospholipid phosphatase 1 | -0.0241587 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0241085 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0241003 |
| HMGB1 | high mobility group box 1 | -0.0240745 |
| HMGB2 | high mobility group box 2 | -0.023712 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0236906 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0236663 |
