| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NG25 perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the NG25_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HDAC9 | histone deacetylase 9 | 0.132246 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.131581 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.103733 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0988015 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0933214 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0867137 |
| STC1 | stanniocalcin 1 | 0.080735 |
| ADM | adrenomedullin | 0.0775268 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0766172 |
| PCBP2 | poly(rC) binding protein 2 | 0.0695344 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0685026 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.066619 |
| B2M | beta-2-microglobulin | 0.0661646 |
| LDHA | lactate dehydrogenase A | 0.0654311 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0632229 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0601179 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0574571 |
| RPS18 | ribosomal protein S18 | 0.0541176 |
| NAV2 | neuron navigator 2 | 0.0526632 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0526411 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.050335 |
| CD44 | CD44 molecule (Indian blood group) | 0.0476448 |
| HLA-A | major histocompatibility complex, class I, A | 0.0473832 |
| GPC6 | glypican 6 | 0.0467221 |
| APP | amyloid beta (A4) precursor protein | 0.0467142 |
| FN1 | fibronectin 1 | 0.0464535 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0458862 |
| VEGFA | vascular endothelial growth factor A | 0.0449537 |
| MCL1 | myeloid cell leukemia 1 | 0.0441002 |
| RUNX1 | runt-related transcription factor 1 | 0.0439737 |
| RND3 | Rho family GTPase 3 | 0.0434281 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0432185 |
| CALR | calreticulin | 0.0430263 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0429545 |
| SFTPA2 | surfactant protein A2 | 0.0422056 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0415487 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0410523 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.04049 |
| SQSTM1 | sequestosome 1 | 0.0402948 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0397181 |
| SMAD3 | SMAD family member 3 | 0.0391615 |
| TNS3 | tensin 3 | 0.0386321 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0375924 |
| FMNL2 | formin-like 2 | 0.0375296 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0373663 |
| VCAN | versican | 0.0369025 |
| ARRDC3 | arrestin domain containing 3 | 0.0357552 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0357169 |
| RPL3 | ribosomal protein L3 | 0.0355129 |
| MSN | moesin | 0.034856 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0347268 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0343802 |
| C3 | complement component 3 | 0.0342114 |
| ASPH | aspartate beta-hydroxylase | 0.0336551 |
| TPM3 | tropomyosin 3 | 0.0331707 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.03308 |
| OPTN | optineurin | 0.0328765 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0328342 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0328137 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0320146 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0320114 |
| MT2A | metallothionein 2A | 0.0319576 |
| VIM | vimentin | 0.0309446 |
| EFNA5 | ephrin-A5 | 0.0308717 |
| ATXN1 | ataxin 1 | 0.0302513 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0302143 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0297858 |
| JMJD1C | jumonji domain containing 1C | 0.0292663 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0288768 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0287859 |
| JUN | jun proto-oncogene | 0.0287402 |
| RNF213 | ring finger protein 213 | 0.0284468 |
| HLA-C | major histocompatibility complex, class I, C | 0.0281873 |
| SP100 | SP100 nuclear antigen | 0.0281576 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0276012 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.026777 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0265883 |
| KLF6 | Kruppel-like factor 6 | 0.0264991 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0258688 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0258565 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.025628 |
| MYO10 | myosin X | 0.0252417 |
| SVIL | supervillin | 0.0250263 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0250054 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0248855 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0248478 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0247903 |
| MX1 | MX dynamin-like GTPase 1 | 0.0246171 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0244826 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0243601 |
| PKM | pyruvate kinase, muscle | 0.024264 |
| HMGA1 | high mobility group AT-hook 1 | 0.0239596 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0237531 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0236443 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0235487 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.0234385 |
| HMGA2 | high mobility group AT-hook 2 | 0.0232839 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0231956 |
| ADAR | adenosine deaminase, RNA-specific | 0.0230533 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0227286 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.176813 |
| FRMD4A | FERM domain containing 4A | -0.156861 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.101231 |
| FTL | ferritin, light polypeptide | -0.087184 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0591806 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0505793 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0498529 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0486736 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0469563 |
| ACTG1 | actin gamma 1 | -0.0437624 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0436805 |
| RPL37A | ribosomal protein L37a | -0.0435133 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0430069 |
| IER3 | immediate early response 3 | -0.0423801 |
| CENPF | centromere protein F, 350/400kDa | -0.0422534 |
| RPS6 | ribosomal protein S6 | -0.0393261 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.039213 |
| TMSB10 | thymosin beta 10 | -0.0390749 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0389825 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0371827 |
| MYOF | myoferlin | -0.0356347 |
| RPL35A | ribosomal protein L35a | -0.0351593 |
| RPS24 | ribosomal protein S24 | -0.0315057 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0272515 |
| VCL | vinculin | -0.0265498 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0262804 |
| AHNAK | AHNAK nucleoprotein | -0.0250909 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0248558 |
| CTSD | cathepsin D | -0.0239163 |
| RPL9 | ribosomal protein L9 | -0.0227406 |
| RPL37 | ribosomal protein L37 | -0.0226653 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0219221 |
| COL1A1 | collagen, type I, alpha 1 | -0.0218265 |
| HLA-B | major histocompatibility complex, class I, B | -0.0217982 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 | -0.0217852 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0214628 |
| KIF4A | kinesin family member 4A | -0.0212156 |
| RPL34 | ribosomal protein L34 | -0.0209685 |
| TPM4 | tropomyosin 4 | -0.0206093 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0203365 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0203263 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0200908 |
| DST | dystonin | -0.0200005 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0197701 |
| PALLD | palladin, cytoskeletal associated protein | -0.0196567 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0195495 |
| FBXO32 | F-box protein 32 | -0.0195392 |
| TMEM263 | transmembrane protein 263 | -0.0194505 |
| CAVIN1 | caveolae associated protein 1 | -0.0191733 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.018699 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0183413 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0181514 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0179726 |
| PTMA | prothymosin, alpha | -0.0178543 |
| DIAPH2 | diaphanous-related formin 2 | -0.0178089 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0175939 |
| ANLN | anillin, actin binding protein | -0.0175923 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0175274 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0174208 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0174202 |
| LRRC7 | leucine rich repeat containing 7 | -0.0174165 |
| RPL19 | ribosomal protein L19 | -0.0174035 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0173218 |
| MKI67 | marker of proliferation Ki-67 | -0.0172962 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0171714 |
| LOX | lysyl oxidase | -0.0171575 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0170216 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0170174 |
| RPL11 | ribosomal protein L11 | -0.0170064 |
| CNTN6 | contactin 6 | -0.016955 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0168834 |
| OGA | O-GlcNAcase | -0.0166273 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0165792 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.0164642 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0163225 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0161512 |
| RPLP1 | ribosomal protein, large, P1 | -0.0159457 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0156486 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0155528 |
| GOLGA4 | golgin A4 | -0.0155164 |
| RPL31 | ribosomal protein L31 | -0.0155137 |
| RPS21 | ribosomal protein S21 | -0.0153381 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0152684 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0151486 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0150825 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0148928 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0147865 |
| FUS | FUS RNA binding protein | -0.0147624 |
| RPS27A | ribosomal protein S27a | -0.0145233 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0144054 |
| TENM2 | teneurin transmembrane protein 2 | -0.0143683 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0143126 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0142842 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0140973 |
| THOC2 | THO complex 2 | -0.0140267 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0139667 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0138327 |
| PCBP3 | poly(rC) binding protein 3 | -0.0137622 |
| INSIG1 | insulin induced gene 1 | -0.0136216 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0135615 |
