| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NG25 perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the NG25_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.219694 |
| VIM | vimentin | 0.150756 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.149437 |
| FN1 | fibronectin 1 | 0.113313 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.111262 |
| STC1 | stanniocalcin 1 | 0.109193 |
| MT2A | metallothionein 2A | 0.103122 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.100534 |
| B2M | beta-2-microglobulin | 0.0899414 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0862703 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.084469 |
| IL6 | interleukin 6 | 0.0844243 |
| CDH13 | cadherin 13 | 0.0835705 |
| ENO1 | enolase 1, (alpha) | 0.0822976 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0788944 |
| POTEF | POTE ankyrin domain family, member F | 0.0778825 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.076638 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0727651 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0692454 |
| LDHA | lactate dehydrogenase A | 0.0680947 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0652064 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0641652 |
| MAP1B | microtubule-associated protein 1B | 0.0639587 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0634693 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0622471 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0619616 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0609924 |
| ADM | adrenomedullin | 0.0584867 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0567424 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.056508 |
| HLA-A | major histocompatibility complex, class I, A | 0.055747 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0544987 |
| PRSS23 | protease, serine, 23 | 0.0535922 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0531582 |
| VEGFA | vascular endothelial growth factor A | 0.0526575 |
| ECE1 | endothelin converting enzyme 1 | 0.0525674 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0516972 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0499298 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0476037 |
| LOX | lysyl oxidase | 0.0464739 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0463612 |
| CD44 | CD44 molecule (Indian blood group) | 0.0460039 |
| COL5A1 | collagen, type V, alpha 1 | 0.0452385 |
| TNS3 | tensin 3 | 0.0451084 |
| PCBP2 | poly(rC) binding protein 2 | 0.042737 |
| GOLGB1 | golgin B1 | 0.0426168 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0420918 |
| LOXL2 | lysyl oxidase-like 2 | 0.0409326 |
| CALR | calreticulin | 0.0405573 |
| VEGFC | vascular endothelial growth factor C | 0.0405382 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0402348 |
| CANX | calnexin | 0.0400784 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0400117 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0399834 |
| EGFR | epidermal growth factor receptor | 0.039845 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0395013 |
| INTS6 | integrator complex subunit 6 | 0.0390798 |
| CDK6 | cyclin-dependent kinase 6 | 0.0383913 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.037921 |
| KYNU | kynureninase | 0.0377538 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0376976 |
| RND3 | Rho family GTPase 3 | 0.0376386 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0374683 |
| MSN | moesin | 0.0373422 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0364799 |
| AHNAK | AHNAK nucleoprotein | 0.0363445 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0358889 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0356852 |
| RAI14 | retinoic acid induced 14 | 0.0356691 |
| PTGES2 | prostaglandin E synthase 2 | 0.0352502 |
| GLIS3 | GLIS family zinc finger 3 | 0.0347737 |
| PKM | pyruvate kinase, muscle | 0.0343949 |
| ANXA5 | annexin A5 | 0.0342557 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0341325 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0337241 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0332401 |
| PDLIM5 | PDZ and LIM domain 5 | 0.033219 |
| MYLK | myosin light chain kinase | 0.0325929 |
| ATXN1 | ataxin 1 | 0.0321814 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0318912 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0317306 |
| MCL1 | myeloid cell leukemia 1 | 0.0316901 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0316492 |
| HMGA2 | high mobility group AT-hook 2 | 0.0309684 |
| GLG1 | golgi glycoprotein 1 | 0.0309058 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0307968 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0306101 |
| TPM3 | tropomyosin 3 | 0.0304567 |
| NRXN3 | neurexin 3 | 0.0301957 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.029867 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0295746 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0295006 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0291231 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0290807 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.029053 |
| PTK2 | protein tyrosine kinase 2 | 0.0290347 |
| TPM2 | tropomyosin 2 (beta) | 0.0286026 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0285008 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0269143 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0265391 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.155398 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.124531 |
| FAM13A | family with sequence similarity 13, member A | -0.0628676 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0556043 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0552472 |
| FTL | ferritin, light polypeptide | -0.0466712 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.046262 |
| COL1A2 | collagen, type I, alpha 2 | -0.0458483 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0395996 |
| H3-3B | H3.3 histone B | -0.0394861 |
| ZNF292 | zinc finger protein 292 | -0.0379472 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0357451 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0353033 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0352057 |
| PRELID2 | PRELI domain containing 2 | -0.0344804 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0338206 |
| ATP13A3 | ATPase type 13A3 | -0.0326208 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0324122 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0322924 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0320657 |
| PDE10A | phosphodiesterase 10A | -0.0318578 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.031816 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0308369 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0300677 |
| RPS24 | ribosomal protein S24 | -0.0279106 |
| RPS12 | ribosomal protein S12 | -0.02776 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0273019 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0272126 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0272054 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.02672 |
| AUTS2 | autism susceptibility candidate 2 | -0.0265976 |
| RPL35A | ribosomal protein L35a | -0.0263955 |
| TLK1 | tousled-like kinase 1 | -0.0258664 |
| RNF216 | ring finger protein 216 | -0.0253001 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0252372 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0249984 |
| HMGB2 | high mobility group box 2 | -0.0249974 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0249742 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0248726 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0247916 |
| NRG1 | neuregulin 1 | -0.0246302 |
| S100A9 | S100 calcium binding protein A9 | -0.024468 |
| TMEM41B | transmembrane protein 41B | -0.0236373 |
| PEG10 | paternally expressed 10 | -0.0234433 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0233006 |
| DENND4C | DENN/MADD domain containing 4C | -0.0230533 |
| TPD52 | tumor protein D52 | -0.0230078 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0228923 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0228666 |
| RPL34 | ribosomal protein L34 | -0.0224696 |
| MEF2A | myocyte enhancer factor 2A | -0.0223969 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0223805 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.022375 |
| RPL28 | ribosomal protein L28 | -0.0222894 |
| RBM25 | RNA binding motif protein 25 | -0.0220782 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0219031 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0217396 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0215317 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0211641 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0210578 |
| RPL27A | ribosomal protein L27a | -0.0209754 |
| PHF21A | PHD finger protein 21A | -0.020971 |
| RYK | receptor-like tyrosine kinase | -0.0204119 |
| CCNI | cyclin I | -0.0198869 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0198455 |
| NOP58 | NOP58 ribonucleoprotein | -0.0198216 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0197386 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0197001 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0196043 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0195573 |
| PAIP2 | poly(A) binding protein interacting protein 2 | -0.0191693 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0189869 |
| OGA | O-GlcNAcase | -0.0189296 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0189263 |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | -0.0188472 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | -0.0188165 |
| GOLGA4 | golgin A4 | -0.0187939 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0187296 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0185786 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0184721 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0183699 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0183576 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0179959 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0179336 |
| RPS5 | ribosomal protein S5 | -0.0179147 |
| PHKB | phosphorylase kinase, beta | -0.0179102 |
| USP3 | ubiquitin specific peptidase 3 | -0.0179101 |
| CTSD | cathepsin D | -0.0178861 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0178277 |
| RBM6 | RNA binding motif protein 6 | -0.0178173 |
| GTF2B | general transcription factor IIB | -0.0178015 |
| RTN4 | reticulon 4 | -0.0177313 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | -0.0177095 |
| ATP11B | ATPase, class VI, type 11B | -0.0176941 |
| RPL19 | ribosomal protein L19 | -0.0176867 |
| SERINC1 | serine incorporator 1 | -0.0176339 |
| CCDC6 | coiled-coil domain containing 6 | -0.017621 |
| DYM | dymeclin | -0.0175498 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0174611 |
| RPS21 | ribosomal protein S21 | -0.0173415 |
