| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NG25 perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the NG25_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.094932 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0843105 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0777044 |
| POTEF | POTE ankyrin domain family, member F | 0.0717891 |
| LDHA | lactate dehydrogenase A | 0.0680711 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0625914 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0589872 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0582646 |
| SMAD3 | SMAD family member 3 | 0.0576894 |
| CD44 | CD44 molecule (Indian blood group) | 0.0573145 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0555042 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0549847 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0524109 |
| SVIL | supervillin | 0.0522079 |
| MT2A | metallothionein 2A | 0.0504282 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0491211 |
| TXNIP | thioredoxin interacting protein | 0.0485512 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0477076 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0465291 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0460592 |
| B2M | beta-2-microglobulin | 0.0454197 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0437268 |
| HPCAL1 | hippocalcin-like 1 | 0.0435811 |
| ASPH | aspartate beta-hydroxylase | 0.0430633 |
| ADM | adrenomedullin | 0.0421081 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0419409 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0411178 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.040984 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0408724 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0401758 |
| SQSTM1 | sequestosome 1 | 0.0396322 |
| AXL | AXL receptor tyrosine kinase | 0.0388889 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0388249 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0383803 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0373081 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0368354 |
| VIM | vimentin | 0.0366298 |
| E2F7 | E2F transcription factor 7 | 0.0363114 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0343942 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0339832 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0338502 |
| ATP13A3 | ATPase type 13A3 | 0.0337153 |
| HLA-B | major histocompatibility complex, class I, B | 0.0332151 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0332078 |
| GOLGA2 | golgin A2 | 0.0330417 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0327349 |
| RND3 | Rho family GTPase 3 | 0.0325613 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.03218 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.031984 |
| RPS18 | ribosomal protein S18 | 0.031925 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0311286 |
| PCBP2 | poly(rC) binding protein 2 | 0.0307108 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0303456 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0300845 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0298935 |
| TPM3 | tropomyosin 3 | 0.0297977 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0297015 |
| ANXA2 | annexin A2 | 0.0295939 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0294344 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0293138 |
| ANXA1 | annexin A1 | 0.0292157 |
| HBEGF | heparin-binding EGF-like growth factor | 0.0291739 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0289365 |
| GPC5 | glypican 5 | 0.0287964 |
| FAF2 | Fas associated factor family member 2 | 0.0285199 |
| RPL12 | ribosomal protein L12 | 0.0284571 |
| NDRG1 | N-myc downstream regulated 1 | 0.0282948 |
| QSER1 | glutamine and serine rich 1 | 0.0282178 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0281668 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0276785 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0271893 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.026945 |
| AFTPH | aftiphilin | 0.0261849 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0260625 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0259759 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.025819 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0257356 |
| CD9 | CD9 molecule | 0.0248528 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0248361 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0247703 |
| CCNL1 | cyclin L1 | 0.0246215 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0245529 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0243079 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0240908 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0239679 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0239456 |
| SASH1 | SAM and SH3 domain containing 1 | 0.0238878 |
| LMNA | lamin A/C | 0.0238519 |
| TTC1 | tetratricopeptide repeat domain 1 | 0.0237542 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0236535 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0235853 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0233471 |
| RDX | radixin | 0.0233463 |
| ACTG1 | actin gamma 1 | 0.0231753 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0231633 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0230211 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.0227153 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0225924 |
| ENO1 | enolase 1, (alpha) | 0.0225217 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0224656 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.104307 |
| SMYD3 | SET and MYND domain containing 3 | -0.0879159 |
| HMGA2 | high mobility group AT-hook 2 | -0.0834789 |
| DST | dystonin | -0.0730053 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0725785 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0698087 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.069572 |
| FUS | FUS RNA binding protein | -0.0665448 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0639103 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.063179 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0611125 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.059027 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0565243 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0556463 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.055495 |
| ATM | ATM serine/threonine kinase | -0.0550183 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0541007 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0534493 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0528056 |
| OGA | O-GlcNAcase | -0.0525517 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0522417 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0522149 |
| GOLGA4 | golgin A4 | -0.0513044 |
| PRSS23 | protease, serine, 23 | -0.0504503 |
| RSF1 | remodeling and spacing factor 1 | -0.0501922 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0500982 |
| EXOC4 | exocyst complex component 4 | -0.0494331 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0492282 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0488434 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0485907 |
| ATG7 | autophagy related 7 | -0.0485288 |
| ACER3 | alkaline ceramidase 3 | -0.0482684 |
| UBC | ubiquitin C | -0.0471998 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0466127 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0463235 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0459873 |
| RIGI | RNA sensor RIG-I | -0.0457086 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0448748 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0441866 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0436005 |
| RPS27A | ribosomal protein S27a | -0.0435645 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0431788 |
| CALU | calumenin | -0.0430648 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0425806 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0421669 |
| CLTC | clathrin, heavy chain (Hc) | -0.0416927 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0408658 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0407331 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | -0.0404118 |
| EFNA5 | ephrin-A5 | -0.040094 |
| TCF12 | transcription factor 12 | -0.0393164 |
| DIAPH3 | diaphanous-related formin 3 | -0.0390381 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0387792 |
| NKTR | natural killer cell triggering receptor | -0.0387282 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0385642 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.038428 |
| PRELID2 | PRELI domain containing 2 | -0.0382389 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0381867 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0376962 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0376473 |
| RAD51B | RAD51 paralog B | -0.0376037 |
| RAB10 | RAB10, member RAS oncogene family | -0.0372856 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0371974 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0369645 |
| SPAG9 | sperm associated antigen 9 | -0.0366843 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0363786 |
| ZC3H6 | zinc finger CCCH-type containing 6 | -0.0363277 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0362373 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.035517 |
| PARD3 | par-3 family cell polarity regulator | -0.0353936 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.035303 |
| PTK2 | protein tyrosine kinase 2 | -0.0352465 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0350369 |
| NF1 | neurofibromin 1 | -0.0350128 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.034965 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | -0.0348493 |
| AHNAK | AHNAK nucleoprotein | -0.0346372 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.034438 |
| ATG10 | autophagy related 10 | -0.0343647 |
| ANKRD36C | ankyrin repeat domain 36C | -0.0343156 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0342882 |
| AK1 | adenylate kinase 1 | -0.0340556 |
| DENND1A | DENN/MADD domain containing 1A | -0.0332972 |
| BBX | bobby sox homolog (Drosophila) | -0.0332276 |
| ZNF638 | zinc finger protein 638 | -0.0330031 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0327981 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0327683 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0327365 |
| ZNF292 | zinc finger protein 292 | -0.032194 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0318609 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0316975 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0315406 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0314299 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0312968 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0311495 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.031117 |
| PRKCA | protein kinase C, alpha | -0.0310111 |
| SRPK2 | SRSF protein kinase 2 | -0.0306453 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0306088 |
| ERBIN | erbb2 interacting protein | -0.030435 |
