| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NG25 perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the NG25_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.16787 |
| TXNIP | thioredoxin interacting protein | 0.110036 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0821366 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0820439 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0770011 |
| ASPH | aspartate beta-hydroxylase | 0.074646 |
| TPM3 | tropomyosin 3 | 0.0707655 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0636289 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0603371 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0594672 |
| MCL1 | myeloid cell leukemia 1 | 0.0561475 |
| TMEM156 | transmembrane protein 156 | 0.0552799 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.053557 |
| B2M | beta-2-microglobulin | 0.0502594 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0491988 |
| MAP1B | microtubule-associated protein 1B | 0.0457086 |
| SMAD3 | SMAD family member 3 | 0.0437322 |
| DUSP6 | dual specificity phosphatase 6 | 0.0436786 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0432844 |
| HMGA1 | high mobility group AT-hook 1 | 0.0428468 |
| SIK3 | SIK family kinase 3 | 0.0425788 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.041947 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0418219 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0417808 |
| PCBP2 | poly(rC) binding protein 2 | 0.0412065 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0404789 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0402852 |
| EREG | epiregulin | 0.0400082 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0396329 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0393945 |
| EFNA5 | ephrin-A5 | 0.0384084 |
| ANGPTL4 | angiopoietin-like 4 | 0.0383518 |
| POTEF | POTE ankyrin domain family, member F | 0.0380988 |
| RPS18 | ribosomal protein S18 | 0.0377803 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0373604 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0373483 |
| LMNA | lamin A/C | 0.0364665 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.036074 |
| PKM | pyruvate kinase, muscle | 0.0354733 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0353966 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0352383 |
| CD44 | CD44 molecule (Indian blood group) | 0.0345667 |
| NDRG1 | N-myc downstream regulated 1 | 0.0345402 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.033807 |
| SVIL | supervillin | 0.0325577 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.031588 |
| TOP1 | topoisomerase (DNA) I | 0.030921 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0304907 |
| NTN4 | netrin 4 | 0.0302987 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0302414 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0302239 |
| EZR | ezrin | 0.0295079 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0293406 |
| LOXL2 | lysyl oxidase-like 2 | 0.0289422 |
| AFDN | afadin, adherens junction formation factor | 0.0288448 |
| VIM | vimentin | 0.0285351 |
| EMP1 | epithelial membrane protein 1 | 0.0284156 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0273562 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0269468 |
| GPATCH2L | G patch domain containing 2-like | 0.0265392 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0258883 |
| SEPTIN9 | septin 9 | 0.025808 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0257588 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.025688 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0253489 |
| PTK2 | protein tyrosine kinase 2 | 0.0252448 |
| ANXA5 | annexin A5 | 0.0252086 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0251953 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0251446 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0248513 |
| FLNA | filamin A, alpha | 0.0248119 |
| TGM2 | transglutaminase 2 | 0.0247003 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0245674 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0243606 |
| CRY1 | cryptochrome circadian clock 1 | 0.0243495 |
| CALR | calreticulin | 0.0241689 |
| SON | SON DNA binding protein | 0.0240101 |
| RPL3 | ribosomal protein L3 | 0.0239587 |
| ADAR | adenosine deaminase, RNA-specific | 0.0236601 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0235963 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0234297 |
| FOSL1 | FOS-like antigen 1 | 0.0233953 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.023339 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0232086 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0231127 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0228619 |
| SLTM | SAFB-like, transcription modulator | 0.0228005 |
| RND3 | Rho family GTPase 3 | 0.0225323 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.022521 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0224627 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.022372 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0223615 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0223126 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0222168 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0221351 |
| MYADM | myeloid-associated differentiation marker | 0.0220177 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0219995 |
| PLEC | plectin | 0.0218733 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0218568 |
| YBX3 | Y box binding protein 3 | 0.0216569 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.246196 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.20183 |
| NRG1 | neuregulin 1 | -0.197322 |
| FN1 | fibronectin 1 | -0.156774 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.151221 |
| CENPF | centromere protein F, 350/400kDa | -0.0838886 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0795854 |
| CANX | calnexin | -0.072887 |
| PTMA | prothymosin, alpha | -0.072813 |
| SYT1 | synaptotagmin I | -0.0690992 |
| ITGA1 | integrin, alpha 1 | -0.0678506 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0677484 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0637724 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0626032 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0593098 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0568976 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0563518 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0536818 |
| PALLD | palladin, cytoskeletal associated protein | -0.0531728 |
| HMGA2 | high mobility group AT-hook 2 | -0.0519547 |
| H1-0 | H1.0 linker histone | -0.0490291 |
| CD109 | CD109 molecule | -0.0488369 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0476661 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0419376 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0412594 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0404523 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0398785 |
| TMEM165 | transmembrane protein 165 | -0.0384171 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0370996 |
| HLA-B | major histocompatibility complex, class I, B | -0.0370388 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0369623 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0367739 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0362714 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0348998 |
| TMEM263 | transmembrane protein 263 | -0.0344414 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0337117 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0335307 |
| AHR | aryl hydrocarbon receptor | -0.0333307 |
| TMSB4X | thymosin beta 4, X-linked | -0.0330727 |
| AHNAK | AHNAK nucleoprotein | -0.032617 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0324811 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0323533 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.032197 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0318127 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0314537 |
| AEBP2 | AE binding protein 2 | -0.0311306 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0309897 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.030788 |
| RPL35A | ribosomal protein L35a | -0.0305724 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0305052 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0302768 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0299329 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0298523 |
| FNIP1 | folliculin interacting protein 1 | -0.0297916 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0293657 |
| VCL | vinculin | -0.0291188 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0290887 |
| CTSD | cathepsin D | -0.0288489 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0288238 |
| ZNF217 | zinc finger protein 217 | -0.0281854 |
| GPC6 | glypican 6 | -0.0281406 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0279877 |
| RPLP1 | ribosomal protein, large, P1 | -0.0273034 |
| RAI14 | retinoic acid induced 14 | -0.0268909 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.026648 |
| ZNF292 | zinc finger protein 292 | -0.0265384 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0262388 |
| RPL26 | ribosomal protein L26 | -0.0261257 |
| RPL37A | ribosomal protein L37a | -0.026039 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.025449 |
| FTL | ferritin, light polypeptide | -0.025272 |
| RPL38 | ribosomal protein L38 | -0.0251724 |
| ERO1B | endoplasmic reticulum oxidoreductase 1 beta | -0.0251403 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0246639 |
| PCNX4 | pecanex 4 | -0.0246491 |
| PCDH7 | protocadherin 7 | -0.0245887 |
| MTDH | metadherin | -0.0244798 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0243604 |
| ARF1 | ADP-ribosylation factor 1 | -0.0241953 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0238386 |
| LRRC23 | leucine rich repeat containing 23 | -0.0237655 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0236826 |
| MKI67 | marker of proliferation Ki-67 | -0.0235229 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0232613 |
| XPO1 | exportin 1 | -0.0231282 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0229757 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0229657 |
| RPS27A | ribosomal protein S27a | -0.0228594 |
| AGR2 | anterior gradient 2 | -0.0228007 |
| RPS24 | ribosomal protein S24 | -0.0227569 |
| HMGB3 | high mobility group box 3 | -0.0227491 |
| RSF1 | remodeling and spacing factor 1 | -0.0225616 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0224284 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0223949 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0223917 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0223359 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0223316 |
| TNS3 | tensin 3 | -0.0217364 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0215489 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0215226 |
