| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | nerve growth factor (beta polypeptide)|This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4803) |
| External Link | https://ncbi.nlm.nih.gov/gene/4803 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the NGF gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PRDX2 | peroxiredoxin 2 | 0.0146299 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.0126998 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | 0.0104268 |
| RPA3 | replication protein A3, 14kDa | 0.0103264 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.0100298 |
| HBB | hemoglobin, beta | 0.0100098 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0099982 |
| SST | somatostatin | 0.00990506 |
| AURKB | aurora kinase B | 0.00967803 |
| CST3 | cystatin C | 0.00934051 |
| CDC20 | cell division cycle 20 | 0.00900319 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00898899 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | 0.00886074 |
| RPS5 | ribosomal protein S5 | 0.00885778 |
| KRT1 | keratin 1, type II | 0.0087719 |
| FBXO21 | F-box protein 21 | 0.00876683 |
| CALML5 | calmodulin-like 5 | 0.00874753 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.00872063 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00867 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00863345 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | 0.00859807 |
| ECI2 | enoyl-CoA delta isomerase 2 | 0.00858102 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00847252 |
| TOX3 | TOX high mobility group box family member 3 | 0.00839965 |
| VKORC1 | vitamin K epoxide reductase complex, subunit 1 | 0.00838462 |
| HOXB6 | homeobox B6 | 0.0083613 |
| C7 | complement component 7 | 0.00834862 |
| SLC2A4RG | SLC2A4 regulator | 0.00834416 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00825249 |
| CD99 | CD99 molecule | 0.00820831 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.00818816 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.00818067 |
| OLFM1 | olfactomedin 1 | 0.00818003 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00817216 |
| FGF13 | fibroblast growth factor 13 | 0.00816322 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.00814276 |
| LAGE3 | L antigen family, member 3 | 0.00811821 |
| TXNDC9 | thioredoxin domain containing 9 | 0.00808848 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.00807392 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.00805593 |
| SPC25 | SPC25, NDC80 kinetochore complex component | 0.00802817 |
| MMP2 | matrix metallopeptidase 2 | 0.0080064 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.00797109 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00796483 |
| SEPTIN10 | septin 10 | 0.00794005 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.00791271 |
| FLNA | filamin A, alpha | 0.00788178 |
| LOR | loricrin | 0.00786985 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0078669 |
| TFF3 | trefoil factor 3 (intestinal) | 0.00785342 |
| CRIP2 | cysteine-rich protein 2 | 0.00783699 |
| GSTT1 | glutathione S-transferase theta 1 | 0.00774442 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00774232 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | 0.00772309 |
| ESR1 | estrogen receptor 1 | 0.00771768 |
| FRZB | frizzled-related protein | 0.00769074 |
| FBXO5 | F-box protein 5 | 0.00765709 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | 0.00761833 |
| THYN1 | thymocyte nuclear protein 1 | 0.0075311 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | 0.00742115 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 0.00741348 |
| HYOU1 | hypoxia up-regulated 1 | 0.00734974 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.00734394 |
| OIP5 | Opa interacting protein 5 | 0.00733587 |
| GSTA4 | glutathione S-transferase alpha 4 | 0.00730631 |
| FASTKD3 | FAST kinase domains 3 | 0.0072873 |
| PLN | phospholamban | 0.00724862 |
| ASF1B | anti-silencing function 1B histone chaperone | 0.00723567 |
| PIMREG | PICALM interacting mitotic regulator | 0.0072303 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00722595 |
| NVL | nuclear VCP-like | 0.00712502 |
| SPON1 | spondin 1, extracellular matrix protein | 0.00709445 |
| DSC1 | desmocollin 1 | 0.00709117 |
| RNF167 | ring finger protein 167 | 0.00707688 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.00706987 |
| TIA1 | TIA1 cytotoxic granule-associated RNA binding protein | 0.00706224 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.00706181 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.00703989 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00702641 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00702596 |
| CDCA3 | cell division cycle associated 3 | 0.00700731 |
| NMU | neuromedin U | 0.0069588 |
| ATRAID | all-trans retinoic acid-induced differentiation factor | 0.00695456 |
| COL1A2 | collagen, type I, alpha 2 | 0.00690529 |
| ATP5ME | ATP synthase membrane subunit e | 0.0068939 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | 0.00685763 |
| ESD | esterase D | 0.00682974 |
| ACP6 | acid phosphatase 6, lysophosphatidic | 0.00682804 |
| RRAGA | Ras-related GTP binding A | 0.00678177 |
| PSRC1 | proline/serine-rich coiled-coil 1 | 0.00677941 |
| HAT1 | histone acetyltransferase 1 | 0.00677697 |
| PLK1 | polo-like kinase 1 | 0.00676993 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.00676971 |
| DEFB1 | defensin, beta 1 | 0.00675489 |
| CCNB2 | cyclin B2 | 0.0067536 |
| COX7B | cytochrome c oxidase subunit VIIb | 0.00673364 |
| TRMT5 | tRNA methyltransferase 5 | 0.00672672 |
| ZDHHC4 | zinc finger, DHHC-type containing 4 | 0.00669161 |
| KRT2 | keratin 2, type II | 0.00668555 |
| GLB1L2 | galactosidase, beta 1-like 2 | 0.00667639 |
| ACTB | actin, beta | 0.0066706 |
| KLHL23 | kelch-like family member 23 | 0.00667017 |
| PPA2 | pyrophosphatase (inorganic) 2 | 0.00666868 |
| F13A1 | coagulation factor XIII, A1 polypeptide | 0.00664311 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00662476 |
| CIRBP | cold inducible RNA binding protein | 0.00656409 |
| ANKRD49 | ankyrin repeat domain 49 | 0.00654193 |
| DIXDC1 | DIX domain containing 1 | 0.00653129 |
| ATP5F1D | ATP synthase F1 subunit delta | 0.00652508 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | 0.00652272 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | 0.00646943 |
| DSG1 | desmoglein 1 | 0.00642239 |
| TMEM45A | transmembrane protein 45A | 0.00641267 |
| RIOX2 | ribosomal oxygenase 2 | 0.00640292 |
| RAB20 | RAB20, member RAS oncogene family | 0.00639111 |
| TYRP1 | tyrosinase-related protein 1 | 0.00638936 |
| ALDOA | aldolase A, fructose-bisphosphate | 0.00638455 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00636937 |
| ARG1 | arginase 1 | 0.00636406 |
| HOXB7 | homeobox B7 | 0.00636105 |
| COQ8A | coenzyme Q8A | 0.00635999 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0063585 |
| NIT1 | nitrilase 1 | 0.00635538 |
| CRLF1 | cytokine receptor-like factor 1 | 0.00635025 |
| TXNIP | thioredoxin interacting protein | 0.00634923 |
| MFAP4 | microfibrillar-associated protein 4 | 0.00634812 |
| ELP5 | elongator acetyltransferase complex subunit 5 | 0.00634138 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.00630978 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | 0.00629563 |
| TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | 0.00628051 |
| CFH | complement factor H | 0.00626516 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.00626011 |
| MSX1 | msh homeobox 1 | 0.00624994 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.00624474 |
| NDP | Norrie disease (pseudoglioma) | 0.00624074 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.00624051 |
| COPA | coatomer protein complex, subunit alpha | 0.00623897 |
| LIG1 | ligase I, DNA, ATP-dependent | 0.00622197 |
| FANCL | Fanconi anemia, complementation group L | 0.00621396 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00621357 |
| CHMP6 | charged multivesicular body protein 6 | 0.00621138 |
| NUP37 | nucleoporin 37kDa | 0.0062048 |
| HOXC6 | homeobox C6 | 0.00618962 |
| NSL1 | NSL1, MIS12 kinetochore complex component | 0.00616347 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.00616214 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | 0.00610286 |
| DDHD2 | DDHD domain containing 2 | 0.00609292 |
| RMI1 | RecQ mediated genome instability 1 | 0.006092 |
| CDCA4 | cell division cycle associated 4 | 0.00609027 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | 0.00608481 |
| B3GNT1 | 0.00607408 | |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.00606474 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00604527 |
| SLC25A11 | solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 | 0.00604355 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | 0.00603045 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00599336 |
| ASF1A | anti-silencing function 1A histone chaperone | 0.00598234 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | 0.0059478 |
| PMF1 | polyamine-modulated factor 1 | 0.00594121 |
| TLCD3A | TLC domain containing 3A | 0.00592764 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0059172 |
| EPHB2 | EPH receptor B2 | 0.00591593 |
| H1-10 | H1.10 linker histone | 0.00591477 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 0.00591353 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | 0.00590461 |
| TMEM106C | transmembrane protein 106C | 0.00589237 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | 0.00587776 |
| BCHE | butyrylcholinesterase | 0.00585963 |
| DHCR7 | 7-dehydrocholesterol reductase | 0.00584242 |
| UQCRC1 | ubiquinol-cytochrome c reductase core protein I | 0.00583817 |
| COMMD8 | COMM domain containing 8 | 0.00582877 |
| LCE2B | late cornified envelope 2B | 0.00582595 |
| CISH | cytokine inducible SH2-containing protein | 0.00581755 |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C | 0.00581691 |
| IL10RB | interleukin 10 receptor, beta | 0.00581267 |
| TSPAN8 | tetraspanin 8 | 0.00580501 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | 0.00579377 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | 0.00577066 |
| IFRD2 | interferon-related developmental regulator 2 | 0.00575589 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.00574991 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 0.00574047 |
| UQCR10 | ubiquinol-cytochrome c reductase, complex III subunit X | 0.00573833 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | 0.00573529 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | 0.00571472 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.00570553 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00570122 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.00569763 |
| PRDX4 | peroxiredoxin 4 | 0.00569162 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | 0.00569085 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 | 0.00568666 |
| H1-0 | H1.0 linker histone | 0.00568664 |
| CDK1 | cyclin-dependent kinase 1 | 0.00568435 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.00564399 |
| DCK | deoxycytidine kinase | 0.00563747 |
| UCKL1 | uridine-cytidine kinase 1-like 1 | 0.00562211 |
| RPL36 | ribosomal protein L36 | 0.00559507 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.00558299 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | 0.00557994 |
| PGM1 | phosphoglucomutase 1 | 0.00557333 |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein | 0.00557233 |
| HOXB2 | homeobox B2 | 0.00556994 |
| VBP1 | von Hippel-Lindau binding protein 1 | 0.00556793 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 | 0.00555988 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) | 0.00555929 |
| ARL5A | ADP-ribosylation factor-like 5A | 0.00555803 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.00555415 |
| CHN2 | chimerin 2 | 0.0055458 |
| NDUFB6 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa | 0.00554439 |
| TADA2A | transcriptional adaptor 2A | 0.00554091 |
| ICAM3 | intercellular adhesion molecule 3 | 0.00552198 |
| PMCH | pro-melanin-concentrating hormone | 0.00551666 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.0055138 |
| DUSP22 | dual specificity phosphatase 22 | 0.0055136 |
| CHKB | choline kinase beta | 0.00551256 |
| KIF18A | kinesin family member 18A | 0.00550157 |
| MYO5C | myosin VC | 0.00549829 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.0054835 |
| MRPL24 | mitochondrial ribosomal protein L24 | 0.00547847 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.00547721 |
| GAS2 | growth arrest-specific 2 | 0.00547704 |
| GET3 | guided entry of tail-anchored proteins factor 3, ATPase | 0.0054766 |
| TCTA | T-cell leukemia translocation altered | 0.00547193 |
| DTYMK | deoxythymidylate kinase (thymidylate kinase) | 0.00547085 |
| OAZ1 | ornithine decarboxylase antizyme 1 | 0.00546635 |
| COL4A5 | collagen, type IV, alpha 5 | 0.00545997 |
| TRAPPC4 | trafficking protein particle complex 4 | 0.00545829 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.00545646 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like | 0.00544259 |
| PON3 | paraoxonase 3 | 0.00543946 |
| FABP6 | fatty acid binding protein 6, ileal | 0.00543567 |
| CCNF | cyclin F | 0.00542642 |
| SRP9 | signal recognition particle 9kDa | 0.00541262 |
| TPRKB | TP53RK binding protein | 0.00540999 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 | 0.0054071 |
| KANK2 | KN motif and ankyrin repeat domains 2 | 0.00540238 |
| COL3A1 | collagen, type III, alpha 1 | 0.00539829 |
| SPAG4 | sperm associated antigen 4 | 0.00538371 |
| CABIN1 | calcineurin binding protein 1 | 0.00538205 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | 0.00535895 |
| SELENOW | selenoprotein W | 0.00535742 |
| CAAP1 | caspase activity and apoptosis inhibitor 1 | 0.00535602 |
| POLR3K | polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa | 0.0053531 |
| PER3 | period circadian clock 3 | 0.00535276 |
| SLURP1 | secreted LY6/PLAUR domain containing 1 | 0.00535091 |
| WDR61 | WD repeat domain 61 | 0.00534411 |
| COQ2 | coenzyme Q2 4-hydroxybenzoate polyprenyltransferase | 0.00533952 |
| MCM2 | minichromosome maintenance complex component 2 | 0.00532892 |
| USP13 | ubiquitin specific peptidase 13 (isopeptidase T-3) | 0.00532293 |
| THAP7 | THAP domain containing 7 | 0.00531795 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA1A | heat shock 70kDa protein 1A | -0.0201151 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0187561 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0153429 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.014874 |
| S100A8 | S100 calcium binding protein A8 | -0.0139628 |
| ANXA1 | annexin A1 | -0.0139484 |
| SIK1 | salt-inducible kinase 1 | -0.0139327 |
| KRT15 | keratin 15, type I | -0.0137762 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0137663 |
| KRT7 | keratin 7, type II | -0.0136795 |
| MMP9 | matrix metallopeptidase 9 | -0.013458 |
| CRYAB | crystallin, alpha B | -0.0134421 |
| KRT19 | keratin 19, type I | -0.0129493 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.0128065 |
| IL1RN | interleukin 1 receptor antagonist | -0.0125854 |
| KRT14 | keratin 14, type I | -0.0123849 |
| ADM | adrenomedullin | -0.012366 |
| KRT13 | keratin 13, type I | -0.0121073 |
| PLK2 | polo-like kinase 2 | -0.0117685 |
| KRT5 | keratin 5, type II | -0.0116226 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0115758 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.0114103 |
| CHP1 | calcineurin-like EF-hand protein 1 | -0.0113215 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.0111944 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | -0.0110475 |
| HTRA1 | HtrA serine peptidase 1 | -0.0109674 |
| ATF3 | activating transcription factor 3 | -0.0108976 |
| S100A10 | S100 calcium binding protein A10 | -0.0106866 |
| CA12 | carbonic anhydrase XII | -0.0105596 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0104749 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.0103692 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.0103574 |
| CTSD | cathepsin D | -0.0102275 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0101609 |
| RGCC | regulator of cell cycle | -0.0100919 |
| NRCAM | neuronal cell adhesion molecule | -0.010055 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0100072 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.00997801 |
| TRIM29 | tripartite motif containing 29 | -0.00979416 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00975242 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.00972015 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.00966701 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.00965301 |
| HMOX1 | heme oxygenase 1 | -0.00954603 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00954497 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.00954285 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.0094959 |
| RND3 | Rho family GTPase 3 | -0.00947802 |
| XIC | X chromosome inactivation center | -0.00946531 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.00940389 |
| NFIL3 | nuclear factor, interleukin 3 regulated | -0.00940156 |
| S100P | S100 calcium binding protein P | -0.00922436 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.00919499 |
| ABLIM1 | actin binding LIM protein 1 | -0.00918043 |
| EMP1 | epithelial membrane protein 1 | -0.00917406 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00909037 |
| PITX3 | paired-like homeodomain 3 | -0.00908262 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | -0.00905731 |
| LXN | latexin | -0.00903506 |
| SPRR3 | small proline-rich protein 3 | -0.0090245 |
| CTSL | cathepsin L | -0.00898272 |
| HIST1H2BD | histone cluster 1, H2bd | -0.00898092 |
| MYOF | myoferlin | -0.00895829 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00895418 |
| GSDME | gasdermin E | -0.00887995 |
| KRT23 | keratin 23, type I | -0.00887229 |
| HIST1H2AC | histone cluster 1, H2ac | -0.00880422 |
| NEU1 | sialidase 1 (lysosomal sialidase) | -0.00875377 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.00872179 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | -0.00868718 |
| STC2 | stanniocalcin 2 | -0.00867605 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.00862273 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.00857613 |
| IRS2 | insulin receptor substrate 2 | -0.00853786 |
| MYO6 | myosin VI | -0.00853212 |
| PDE8B | phosphodiesterase 8B | -0.00848572 |
| POSTN | periostin, osteoblast specific factor | -0.00847474 |
| VAMP8 | vesicle-associated membrane protein 8 | -0.00845591 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.00844556 |
| SCPEP1 | serine carboxypeptidase 1 | -0.00841356 |
| MX1 | MX dynamin-like GTPase 1 | -0.00838424 |
| CCNA2 | cyclin A2 | -0.00837623 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00837561 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | -0.00835662 |
| GNAS | GNAS complex locus | -0.00835172 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00834376 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.00833714 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.00832651 |
| MIR22HG | MIR22 host gene | -0.00825414 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00823765 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | -0.00823639 |
| S100A9 | S100 calcium binding protein A9 | -0.00823352 |
| LAMB1 | laminin, beta 1 | -0.00820958 |
| FN1 | fibronectin 1 | -0.00820924 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00818966 |
| KLF9 | Kruppel-like factor 9 | -0.00813067 |
| MICB | MHC class I polypeptide-related sequence B | -0.00809039 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00802673 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00800879 |
| DUSP5 | dual specificity phosphatase 5 | -0.00800586 |
| RAB29 | RAB29, member RAS oncogene family | -0.00800509 |
| CCN2 | cellular communication network factor 2 | -0.00796241 |
| MBD2 | methyl-CpG binding domain protein 2 | -0.00793474 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00790526 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.007901 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.00790067 |
| WWC1 | WW and C2 domain containing 1 | -0.00789713 |
| FNDC3B | fibronectin type III domain containing 3B | -0.00788467 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0078622 |
| SQSTM1 | sequestosome 1 | -0.00785873 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.00784968 |
| FGF1 | fibroblast growth factor 1 (acidic) | -0.00784293 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.00782255 |
| CAST | calpastatin | -0.00782062 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | -0.00780606 |
| SMAD3 | SMAD family member 3 | -0.00778277 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00772513 |
| MFAP3L | microfibrillar-associated protein 3-like | -0.00771999 |
| PTK2B | protein tyrosine kinase 2 beta | -0.00765709 |
| MT1X | metallothionein 1X | -0.007634 |
| STK38 | serine/threonine kinase 38 | -0.00762423 |
| LPPR4 | lipid phosphate phosphatase-related protein type 4 | -0.00760288 |
| INHBA | inhibin, beta A | -0.00759212 |
| NOTCH1 | notch 1 | -0.0075739 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0075714 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.00755642 |
| PERP | PERP, TP53 apoptosis effector | -0.00755629 |
| AREG | amphiregulin | -0.0075476 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.00753636 |
| SIRPA | signal-regulatory protein alpha | -0.00753548 |
| OLFML2A | olfactomedin-like 2A | -0.00750809 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00744407 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | -0.00743442 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | -0.00742636 |
| MMP7 | matrix metallopeptidase 7 | -0.00741127 |
| RAI14 | retinoic acid induced 14 | -0.00739047 |
| HSPA2 | heat shock 70kDa protein 2 | -0.00738941 |
| TSPO | translocator protein (18kDa) | -0.00734829 |
| BLNK | B-cell linker | -0.00734786 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.00733693 |
| PXDC1 | PX domain containing 1 | -0.0073291 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0073198 |
| KLHL24 | kelch-like family member 24 | -0.00729683 |
| CNTN1 | contactin 1 | -0.0072918 |
| DIPK1A | divergent protein kinase domain 1A | -0.00728732 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.00727979 |
| TFRC | transferrin receptor | -0.00727869 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.00727578 |
| IL6ST | interleukin 6 signal transducer | -0.00726883 |
| VAV3 | vav 3 guanine nucleotide exchange factor | -0.00724605 |
| PEG10 | paternally expressed 10 | -0.00724079 |
| THBS1 | thrombospondin 1 | -0.0072175 |
| KRT6B | keratin 6B, type II | -0.00720611 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00719902 |
| KRT6A | keratin 6A, type II | -0.00718644 |
| CSRP2 | cysteine and glycine-rich protein 2 | -0.00718455 |
| PLAUR | plasminogen activator, urokinase receptor | -0.00715256 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | -0.00714417 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | -0.00713894 |
| MAP7 | microtubule-associated protein 7 | -0.00712436 |
| FKBP11 | FK506 binding protein 11, 19 kDa | -0.00706803 |
| PLBD1 | phospholipase B domain containing 1 | -0.00706599 |
| EHD3 | EH-domain containing 3 | -0.00706255 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | -0.0070406 |
| IER5 | immediate early response 5 | -0.00701389 |
| DSP | desmoplakin | -0.006987 |
| OGFRL1 | opioid growth factor receptor-like 1 | -0.0069785 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.00695422 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.00695298 |
| KRT8 | keratin 8, type II | -0.00694936 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.00692901 |
| EIF6 | eukaryotic translation initiation factor 6 | -0.00688929 |
| C3 | complement component 3 | -0.00687748 |
| COBL | cordon-bleu WH2 repeat protein | -0.00687047 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.00684147 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.00681622 |
| LTF | lactotransferrin | -0.0068067 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -0.00679856 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.00676759 |
| GSDMB | gasdermin B | -0.00675611 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.00674522 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | -0.00672132 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.00672023 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.00671564 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | -0.0066774 |
| DSG3 | desmoglein 3 | -0.0066709 |
| HK2 | hexokinase 2 | -0.00664538 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | -0.00663796 |
| YPEL5 | yippee-like 5 (Drosophila) | -0.00659811 |
| VEGFC | vascular endothelial growth factor C | -0.00659732 |
| LAMC2 | laminin, gamma 2 | -0.00659643 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | -0.00659145 |
| JUP | junction plakoglobin | -0.00658762 |
| C10ORF10 | chromosome 10 open reading frame 10 | -0.00658574 |
| BPGM | 2,3-bisphosphoglycerate mutase | -0.00658168 |
| TSPYL5 | TSPY-like 5 | -0.00657746 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.00656776 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00656048 |
| EDN1 | endothelin 1 | -0.00655482 |
| KRT17 | keratin 17, type I | -0.00654883 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | -0.00651309 |
| CCT2 | chaperonin containing TCP1, subunit 2 (beta) | -0.00650879 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.00647328 |
| CNN3 | calponin 3, acidic | -0.00645429 |
| UPK1B | uroplakin 1B | -0.00644494 |
| ABHD4 | abhydrolase domain containing 4 | -0.00644197 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.00643929 |
| HBEGF | heparin-binding EGF-like growth factor | -0.00643181 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | -0.00641765 |
| TRIP6 | thyroid hormone receptor interactor 6 | -0.0064164 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.00640669 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00640651 |
| MITF | microphthalmia-associated transcription factor | -0.00639289 |
| ELMO1 | engulfment and cell motility 1 | -0.00638922 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0063878 |
| TUBB6 | tubulin, beta 6 class V | -0.00638029 |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa | -0.00637768 |
| OPTN | optineurin | -0.00637366 |
| EPHA2 | EPH receptor A2 | -0.00635857 |
| PGAP3 | post-GPI attachment to proteins 3 | -0.0063552 |
| VEGFA | vascular endothelial growth factor A | -0.00633964 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -0.00633811 |
| EFHD1 | EF-hand domain family, member D1 | -0.00632613 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.00631991 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.00631668 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | -0.00631574 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | -0.00630985 |
| NEBL | nebulette | -0.00630596 |
| GPX2 | glutathione peroxidase 2 | -0.00630043 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | -0.00628767 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.00628259 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | -0.00627235 |
| ECM1 | extracellular matrix protein 1 | -0.00626998 |
| NTM | neurotrimin | -0.00626132 |
| BAG3 | BCL2-associated athanogene 3 | -0.00625545 |
| H1-2 | H1.2 linker histone, cluster member | -0.00622415 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | -0.00621981 |
| FBN2 | fibrillin 2 | -0.00621499 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.00620246 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | -0.00619274 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00616735 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.00616135 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.00616073 |
| TNIK | TRAF2 and NCK interacting kinase | -0.00614784 |
| APOD | apolipoprotein D | -0.0061448 |
| PCDH9 | protocadherin 9 | -0.00614218 |
| FADS3 | fatty acid desaturase 3 | -0.0061365 |
| MFGE8 | milk fat globule-EGF factor 8 protein | -0.00610555 |
| ZNF395 | zinc finger protein 395 | -0.00609704 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.00608361 |
