NKX2-3 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description NK2 homeobox 3|This gene encodes a homeodomain-containing transcription factor. The encoded protein is a member of the NKX family of homeodomain transcription factors. Studies of similar proteins in mouse and rat have indicated a potential role in cellular differentiation.[provided by RefSeq, Mar 2010] (NCBI Entrez Gene Database, 159296)
External Link https://ncbi.nlm.nih.gov/gene/159296
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Genes

499 genes differentially expressed following the NKX2-3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 0.0107541
DEGS1 delta(4)-desaturase, sphingolipid 1 0.0104834
BCHE butyrylcholinesterase 0.0104377
GOLGA8A golgin A8 family, member A 0.010059
CLEC11A C-type lectin domain family 11, member A 0.00991611
EPS8 epidermal growth factor receptor pathway substrate 8 0.00966399
PROS1 protein S (alpha) 0.00951332
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.00921504
ALCAM activated leukocyte cell adhesion molecule 0.00899338
ADAT1 adenosine deaminase, tRNA-specific 1 0.00873548
CXCL9 chemokine (C-X-C motif) ligand 9 0.00872969
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 0.00868143
NKG7 natural killer cell granule protein 7 0.00866824
ZBTB18 zinc finger and BTB domain containing 18 0.00847518
PAN2 PAN2 poly(A) specific ribonuclease subunit 0.00842766
DCXR dicarbonyl/L-xylulose reductase 0.0084003
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.00830497
ARHGAP29 Rho GTPase activating protein 29 0.00827222
NVL nuclear VCP-like 0.0082618
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 0.00822206
EGR3 early growth response 3 0.00820433
GZMK granzyme K (granzyme 3; tryptase II) 0.00819435
UGCG UDP-glucose ceramide glucosyltransferase 0.00814652
RGS4 regulator of G-protein signaling 4 0.00801751
TFF1 trefoil factor 1 0.00800697
CDC20 cell division cycle 20 0.00792841
ANXA10 annexin A10 0.00790809
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.00776494
PLAAT3 phospholipase A and acyltransferase 3 0.00773698
FAM111A family with sequence similarity 111, member A 0.00769866
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.0075725
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 0.007565
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.00710714
TOX3 TOX high mobility group box family member 3 0.00688554
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 0.00677037
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.00674085
SHCBP1 SHC SH2-domain binding protein 1 0.00673158
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00672012
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 0.00671918
HOXC6 homeobox C6 0.00671769
IKZF1 IKAROS family zinc finger 1 (Ikaros) 0.00670933
PTK2 protein tyrosine kinase 2 0.00667085
FASN fatty acid synthase 0.0066596
DGLUCY D-glutamate cyclase 0.00665022
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00664961
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.00663018
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.0066222
ACSL1 acyl-CoA synthetase long-chain family member 1 0.00659167
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2 0.00657401
CCNB2 cyclin B2 0.00654906
CXCL12 chemokine (C-X-C motif) ligand 12 0.00651388
PIEZO1 piezo-type mechanosensitive ion channel component 1 0.00646752
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.00641707
LY6E lymphocyte antigen 6 complex, locus E 0.00641682
CCL5 chemokine (C-C motif) ligand 5 0.00641367
METRN meteorin, glial cell differentiation regulator 0.00638598
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.00634987
PLA1A phospholipase A1 member A 0.0063437
RUFY3 RUN and FYVE domain containing 3 0.00634062
NT5E 5'-nucleotidase, ecto (CD73) 0.00631158
GPX1 glutathione peroxidase 1 0.00624362
PCGF2 polycomb group ring finger 2 0.00623019
PYCARD PYD and CARD domain containing 0.00622602
P4HB prolyl 4-hydroxylase, beta polypeptide 0.00617983
AP1G2 adaptor-related protein complex 1, gamma 2 subunit 0.00617496
TBC1D4 TBC1 domain family, member 4 0.00617483
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.00616374
BST2 bone marrow stromal cell antigen 2 0.00614346
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 0.00612764
C2CD2 C2 calcium-dependent domain containing 2 0.00609175
PLXNB2 plexin B2 0.00608791
AMIGO2 adhesion molecule with Ig-like domain 2 0.00607419
ARMT1 acidic residue methyltransferase 1 0.0060222
ZCCHC24 zinc finger, CCHC domain containing 24 0.00601038
TFF3 trefoil factor 3 (intestinal) 0.00600837
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 0.00599711
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 0.00598428
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.00597241
ZCCHC14 zinc finger, CCHC domain containing 14 0.00595548
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 0.00593579
PLK1 polo-like kinase 1 0.00592543
PKD2 polycystic kidney disease 2 (autosomal dominant) 0.00590224
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.00585277
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.00583574
GOLGA8H golgin A8 family, member H 0.00583472
GLG1 golgi glycoprotein 1 0.00580007
C2CD5 C2 calcium-dependent domain containing 5 0.00579065
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 0.0057724
GPRC5B G protein-coupled receptor, class C, group 5, member B 0.00572685
IRF8 interferon regulatory factor 8 0.00571874
SAMD4A sterile alpha motif domain containing 4A 0.00571671
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 0.00568531
CEL carboxyl ester lipase 0.0056829
MINPP1 multiple inositol-polyphosphate phosphatase 1 0.00566376
PLK2 polo-like kinase 2 0.00564725
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 0.00562877
MLPH melanophilin 0.00558092
AKAP12 A kinase (PRKA) anchor protein 12 0.00557935
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.00557817
TSPYL2 TSPY-like 2 0.00557718
SMS spermine synthase 0.00555976
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 0.00554927
STK39 serine threonine kinase 39 0.00554487
CCL19 chemokine (C-C motif) ligand 19 0.00554428
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae) 0.00554274
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 0.00554131
HAL histidine ammonia-lyase 0.00554065
ERI2 ERI1 exoribonuclease family member 2 0.00552019
USP32P2 ubiquitin specific peptidase 32 pseudogene 2 0.00551156
ERLIN2 ER lipid raft associated 2 0.00549455
SLCO4C1 solute carrier organic anion transporter family, member 4C1 0.00548753
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 0.00547943
OFD1 oral-facial-digital syndrome 1 0.00547138
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit 0.00543814
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.00543663
TSPAN4 tetraspanin 4 0.0054348
TESC tescalcin 0.00543386
TJP2 tight junction protein 2 0.00542222
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.00540907
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 0.00540196
FBXO28 F-box protein 28 0.0054018
SLC39A14 solute carrier family 39 (zinc transporter), member 14 0.0053781
TBCD tubulin folding cofactor D 0.00537599
APMAP adipocyte plasma membrane associated protein 0.0053747
APOD apolipoprotein D 0.00534557
NPY1R neuropeptide Y receptor Y1 0.00534379
TMX4 thioredoxin-related transmembrane protein 4 0.00534179
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 0.00533861
KLF2 Kruppel-like factor 2 0.0053287
METTL17 methyltransferase like 17 0.00532028
BRCA1 breast cancer 1, early onset 0.00528539
SIDT2 SID1 transmembrane family, member 2 0.00528313
KDM6A lysine (K)-specific demethylase 6A 0.00527494
MFAP3L microfibrillar-associated protein 3-like 0.00527098
VCAN versican 0.00524023
ZWINT ZW10 interacting kinetochore protein 0.00523582
NLGN4X neuroligin 4, X-linked 0.00523201
MICALL2 MICAL-like 2 0.00521293
ZNF267 zinc finger protein 267 0.00520431
F12 coagulation factor XII (Hageman factor) 0.00516907
GNG10 guanine nucleotide binding protein (G protein), gamma 10 0.00516671
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.00516585
LAT2 linker for activation of T cells family, member 2 0.00516162
ACADVL acyl-CoA dehydrogenase, very long chain 0.00515471
TRIB2 tribbles pseudokinase 2 0.00514444
ABHD10 abhydrolase domain containing 10 0.00513336
C7 complement component 7 0.00512865
EVI2A ecotropic viral integration site 2A 0.0051125
SH2B3 SH2B adaptor protein 3 0.0051045
OCRL oculocerebrorenal syndrome of Lowe 0.00508899
GREM1 gremlin 1, DAN family BMP antagonist 0.005088
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.00506325
CHRDL1 chordin-like 1 0.00504558
PFKM phosphofructokinase, muscle 0.00501433
RAB13 RAB13, member RAS oncogene family 0.00499886
SACS sacsin molecular chaperone 0.0049953
RACGAP1 Rac GTPase activating protein 1 0.00499403
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 0.00498991
GSDME gasdermin E 0.00497134
TLR4 toll-like receptor 4 0.00496978
FAM3C family with sequence similarity 3, member C 0.00496663
LY96 lymphocyte antigen 96 0.00496583
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 0.00494043
PRPS2 phosphoribosyl pyrophosphate synthetase 2 0.00491682
PRC1 protein regulator of cytokinesis 1 0.00491638
FXYD2 FXYD domain containing ion transport regulator 2 0.00485695
SFRP1 secreted frizzled-related protein 1 0.00484514
ECI2 enoyl-CoA delta isomerase 2 0.00484245
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 0.00484025
SHTN1 shootin 1 0.00483446
ZNF580 zinc finger protein 580 0.00483236
CPOX coproporphyrinogen oxidase 0.00482517
KIF18B kinesin family member 18B 0.00480944
RUFY2 RUN and FYVE domain containing 2 0.00478116
IGF1 insulin-like growth factor 1 (somatomedin C) 0.00477364
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.00476474
ELF1 E74-like factor 1 (ets domain transcription factor) 0.00476464
PROM1 prominin 1 0.0047645
PTCH1 patched 1 0.00475114
MBD1 methyl-CpG binding domain protein 1 0.0047498
METTL7A methyltransferase like 7A 0.0047458
PFKL phosphofructokinase, liver 0.00474515
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 0.00473422
EI24 etoposide induced 2.4 0.00473422
COL10A1 collagen, type X, alpha 1 0.00472575
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.00472568
WDR13 WD repeat domain 13 0.00472026
MAGED1 melanoma antigen family D1 0.00471714
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 0.00471593
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.004712
SOAT1 sterol O-acyltransferase 1 0.00470221
PLAT plasminogen activator, tissue 0.0046859
TMED5 transmembrane emp24 protein transport domain containing 5 0.00468075
TM4SF4 transmembrane 4 L six family member 4 0.00468021
AP2S1 adaptor-related protein complex 2, sigma 1 subunit 0.00468003
CLGN calmegin 0.00467935
ZBTB20 zinc finger and BTB domain containing 20 0.00467778
KLHL3 kelch-like family member 3 0.00467441
STX16 syntaxin 16 0.00465392
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.00464982
TMEM255A transmembrane protein 255A 0.00464595
FGL2 fibrinogen-like 2 0.00463788
BCL2L1 BCL2-like 1 0.00463221
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.00462662
PPP1R7 protein phosphatase 1, regulatory subunit 7 0.00462385
VEGFC vascular endothelial growth factor C 0.00461333
RGS1 regulator of G-protein signaling 1 0.00461279
CCR2 chemokine (C-C motif) receptor 2 0.00460944
MOSPD1 motile sperm domain containing 1 0.00460711
USO1 USO1 vesicle transport factor 0.0046042
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit 0.00459386
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 0.00459092
ELANE elastase, neutrophil expressed 0.00457993
MT2A metallothionein 2A 0.00456915
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.00456305
GCC2 GRIP and coiled-coil domain containing 2 0.00456253
LY86 lymphocyte antigen 86 0.00453414
MGST2 microsomal glutathione S-transferase 2 0.0045189
RADX RPA1 related single stranded DNA binding protein, X-linked 0.00450286
RNF144A ring finger protein 144A 0.00449973
IL7R interleukin 7 receptor 0.00449897
RAB17 RAB17, member RAS oncogene family 0.00449416
FAM13A family with sequence similarity 13, member A 0.00448494
RNF6 ring finger protein (C3H2C3 type) 6 0.0044802
NBEAL2 neurobeachin-like 2 0.00445493
LDOC1 leucine zipper, down-regulated in cancer 1 0.00445182
LMO2 LIM domain only 2 (rhombotin-like 1) 0.00444083
MMP11 matrix metallopeptidase 11 0.00443574
MICU2 mitochondrial calcium uptake 2 0.00442687
TM7SF2 transmembrane 7 superfamily member 2 0.00442671
WDFY3 WD repeat and FYVE domain containing 3 0.00441666
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 0.00441594
EGR2 early growth response 2 0.00441311
INTS6 integrator complex subunit 6 0.00441088
ANXA9 annexin A9 0.00440798
TNIK TRAF2 and NCK interacting kinase 0.00440759
DPYD dihydropyrimidine dehydrogenase 0.00440468
TMPRSS4 transmembrane protease, serine 4 0.00440349
TCTA T-cell leukemia translocation altered 0.00440174
TRAPPC2L trafficking protein particle complex 2-like 0.0043952
ADGRF5 adhesion G protein-coupled receptor F5 0.00439321
MDFIC MyoD family inhibitor domain containing 0.00438949
DACT1 dishevelled-binding antagonist of beta-catenin 1 0.00438612
SH3BP4 SH3-domain binding protein 4 0.00438337
RBM47 RNA binding motif protein 47 0.00438184
WASF1 WAS protein family, member 1 0.00437468
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 0.00435196
SDR39U1 short chain dehydrogenase/reductase family 39U, member 1 0.00434437
ATM ATM serine/threonine kinase 0.00434205
SRGN serglycin 0.00433876

decreased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 -0.0297032
MAP7 microtubule-associated protein 7 -0.0271403
SEPP1 selenoprotein P, plasma, 1 -0.0169933
AQP3 aquaporin 3 (Gill blood group) -0.0144777
KRT5 keratin 5, type II -0.0126581
RGCC regulator of cell cycle -0.0120549
AKR1C3 aldo-keto reductase family 1, member C3 -0.0118628
KRT13 keratin 13, type I -0.0118093
AUTS2 autism susceptibility candidate 2 -0.0115505
GNAS GNAS complex locus -0.0112348
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.0112155
FABP5 fatty acid binding protein 5 (psoriasis-associated) -0.0111994
AKR1C2 aldo-keto reductase family 1, member C2 -0.0111446
TM4SF1 transmembrane 4 L six family member 1 -0.0111088
ADM adrenomedullin -0.0109239
ANGPT1 angiopoietin 1 -0.0108023
KRT6A keratin 6A, type II -0.0105827
CADM1 cell adhesion molecule 1 -0.0105144
AOC1 amine oxidase, copper containing 1 -0.0104246
S100P S100 calcium binding protein P -0.0102357
MALL mal, T-cell differentiation protein-like -0.00998178
SPRR3 small proline-rich protein 3 -0.00989382
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.00984041
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.0097932
SIRT3 sirtuin 3 -0.00976363
NEBL nebulette -0.00957692
IFITM1 interferon induced transmembrane protein 1 -0.00954099
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -0.00949977
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.00938796
TPM4 tropomyosin 4 -0.00925511
ABLIM1 actin binding LIM protein 1 -0.00919381
GJA1 gap junction protein, alpha 1, 43kDa -0.00919288
S100A2 S100 calcium binding protein A2 -0.0091023
EMP1 epithelial membrane protein 1 -0.00908956
ELN elastin -0.00908033
AGR2 anterior gradient 2 -0.00900856
CLCA4 chloride channel accessory 4 -0.0089428
GLUL glutamate-ammonia ligase -0.00888183
FGFBP1 fibroblast growth factor binding protein 1 -0.00885668
MMP10 matrix metallopeptidase 10 -0.00877752
DSG3 desmoglein 3 -0.00877744
LAMP3 lysosomal-associated membrane protein 3 -0.0087192
HSPA2 heat shock 70kDa protein 2 -0.0086111
FAM107A family with sequence similarity 107, member A -0.00860648
SPON1 spondin 1, extracellular matrix protein -0.00856244
KRT16 keratin 16, type I -0.00849844
NRCAM neuronal cell adhesion molecule -0.00849436
TPD52 tumor protein D52 -0.00842641
HEBP2 heme binding protein 2 -0.00838891
CPA3 carboxypeptidase A3 (mast cell) -0.0083822
PI3 peptidase inhibitor 3, skin-derived -0.00837099
PERP PERP, TP53 apoptosis effector -0.00829239
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -0.00825249
AKR1C1 aldo-keto reductase family 1, member C1 -0.00823554
MMP12 matrix metallopeptidase 12 -0.00823171
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.00820159
KRT19 keratin 19, type I -0.0081842
ANXA1 annexin A1 -0.00817395
DACH1 dachshund family transcription factor 1 -0.00815945
CLIC5 chloride intracellular channel 5 -0.00809972
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00808082
IL13RA2 interleukin 13 receptor, alpha 2 -0.00800314
SPINK5 serine peptidase inhibitor, Kazal type 5 -0.00799721
SLPI secretory leukocyte peptidase inhibitor -0.00797936
A2M alpha-2-macroglobulin -0.00793293
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) -0.00789835
SDC2 syndecan 2 -0.00789769
PLPP3 phospholipid phosphatase 3 -0.00787867
KRT6B keratin 6B, type II -0.00783949
F3 coagulation factor III (thromboplastin, tissue factor) -0.00777788
KRT15 keratin 15, type I -0.00765775
MCOLN1 mucolipin 1 -0.00753142
MGLL monoglyceride lipase -0.00753116
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.00748038
TUBB2A tubulin, beta 2A class IIa -0.0074707
ITGA8 integrin, alpha 8 -0.00746381
CD59 CD59 molecule, complement regulatory protein -0.00736581
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.0073198
CRABP2 cellular retinoic acid binding protein 2 -0.00731444
NPR3 natriuretic peptide receptor 3 -0.00731064
RBM34 RNA binding motif protein 34 -0.00726618
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00723662
NAMPT nicotinamide phosphoribosyltransferase -0.00722432
CLCA1 chloride channel accessory 1 -0.00721663
CRYAB crystallin, alpha B -0.00720019
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -0.00719952
CP ceruloplasmin (ferroxidase) -0.00718089
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.00711329
MT1M metallothionein 1M -0.00710039
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.00708162
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.00703045
TUBB2B tubulin, beta 2B class IIb -0.00700861
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) -0.00695577
TNIP1 TNFAIP3 interacting protein 1 -0.00693165
CTSZ cathepsin Z -0.0068823
RHOBTB3 Rho-related BTB domain containing 3 -0.00687792
PTHLH parathyroid hormone-like hormone -0.00687647
CPE carboxypeptidase E -0.00685171
MFAP2 microfibrillar-associated protein 2 -0.00682068
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 -0.00681972
PCOLCE2 procollagen C-endopeptidase enhancer 2 -0.00681809
ITGA6 integrin, alpha 6 -0.00677272
CA4 carbonic anhydrase IV -0.00676985
GPC3 glypican 3 -0.006738
CD52 CD52 molecule -0.00672991
SLC26A3 solute carrier family 26 (anion exchanger), member 3 -0.00672914
DLK1 delta-like 1 homolog (Drosophila) -0.00669582
KIAA0226L KIAA0226-like -0.00669164
FBN2 fibrillin 2 -0.00668301
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -0.00667902
SOWAHC sosondowah ankyrin repeat domain family member C -0.00667091
EGFL6 EGF-like-domain, multiple 6 -0.00666474
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.00665296
PPL periplakin -0.00663531
ZIC1 Zic family member 1 -0.00663207
TDP2 tyrosyl-DNA phosphodiesterase 2 -0.00662851
TRPS1 trichorhinophalangeal syndrome I -0.00660582
NRIP3 nuclear receptor interacting protein 3 -0.00657626
E2F5 E2F transcription factor 5, p130-binding -0.00654037
KRT14 keratin 14, type I -0.00652706
SPRR1B small proline-rich protein 1B -0.00652537
PCP4 Purkinje cell protein 4 -0.00650459
TGFBI transforming growth factor, beta-induced, 68kDa -0.00649303
CD177 CD177 molecule -0.00648896
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.00648072
DENND1B DENN/MADD domain containing 1B -0.0064766
LEFTY1 left-right determination factor 1 -0.00646982
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -0.00643263
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.0064248
ACKR3 atypical chemokine receptor 3 -0.00641873
MAP2K6 mitogen-activated protein kinase kinase 6 -0.00635743
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -0.00631965
CHGB chromogranin B -0.00631255
ABHD17B abhydrolase domain containing 17B -0.00627882
CXCL3 chemokine (C-X-C motif) ligand 3 -0.00626865
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) -0.00623739
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -0.0062335
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 -0.0062249
FCGBP Fc fragment of IgG binding protein -0.0061721
PCSK1 proprotein convertase subtilisin/kexin type 1 -0.00617187
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -0.00617044
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) -0.00616135
FABP1 fatty acid binding protein 1, liver -0.00614945
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.00612529
PKP1 plakophilin 1 -0.00611562
BEX4 brain expressed, X-linked 4 -0.00610866
CHKB choline kinase beta -0.00603008
CLEC2B C-type lectin domain family 2, member B -0.00602393
MRPL13 mitochondrial ribosomal protein L13 -0.00601699
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00601651
CNTN1 contactin 1 -0.00601495
NDRG1 N-myc downstream regulated 1 -0.00601222
C12ORF49 chromosome 12 open reading frame 49 -0.00600316
COL9A3 collagen, type IX, alpha 3 -0.00597733
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.00595061
SH3BGR SH3 domain binding glutamate-rich protein -0.00593802
CA2 carbonic anhydrase II -0.00593244
MAL mal, T-cell differentiation protein -0.0059155
HTRA1 HtrA serine peptidase 1 -0.00590875
MAOA monoamine oxidase A -0.00590828
SCRG1 stimulator of chondrogenesis 1 -0.00588735
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00587562
KLF6 Kruppel-like factor 6 -0.00587262
MUC2 mucin 2, oligomeric mucus/gel-forming -0.00585658
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 -0.00585148
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.00578619
AQP4 aquaporin 4 -0.00577331
COG7 component of oligomeric golgi complex 7 -0.00577303
EPS8L2 EPS8-like 2 -0.00576947
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.00576267
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 -0.00575686
ESRP1 epithelial splicing regulatory protein 1 -0.0057455
ADGRL2 adhesion G protein-coupled receptor L2 -0.00572313
TALDO1 transaldolase 1 -0.00571126
CHI3L2 chitinase 3-like 2 -0.00570874
TXN thioredoxin -0.00570573
RFTN1 raftlin, lipid raft linker 1 -0.00569613
PLBD1 phospholipase B domain containing 1 -0.00568862
MXD1 MAX dimerization protein 1 -0.00568821
LMO3 LIM domain only 3 (rhombotin-like 2) -0.00566656
PITX1 paired-like homeodomain 1 -0.00565446
LYPD3 LY6/PLAUR domain containing 3 -0.00563818
BTG1 B-cell translocation gene 1, anti-proliferative -0.00563806
ELL2 elongation factor, RNA polymerase II, 2 -0.0056335
FOLR1 folate receptor 1 (adult) -0.00560481
FHL1 four and a half LIM domains 1 -0.00558651
CD44 CD44 molecule (Indian blood group) -0.00558601
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -0.0055699
TUBA4A tubulin, alpha 4a -0.00556293
KIAA0125 KIAA0125 -0.0055503
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -0.00554973
MFAP4 microfibrillar-associated protein 4 -0.00554452
ANXA11 annexin A11 -0.00553762
COLEC12 collectin sub-family member 12 -0.00552438
EPAS1 endothelial PAS domain protein 1 -0.00552127
MUC5B mucin 5B, oligomeric mucus/gel-forming -0.00551271
BAALC brain and acute leukemia, cytoplasmic -0.00549839
CCDC86 coiled-coil domain containing 86 -0.0054952
NDNF neuron-derived neurotrophic factor -0.00546587
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 -0.00546525
KRT23 keratin 23, type I -0.00545942
KLF5 Kruppel-like factor 5 (intestinal) -0.00543819
CD9 CD9 molecule -0.00543243
SPRR1A small proline-rich protein 1A -0.0054209
BMP7 bone morphogenetic protein 7 -0.00540339
HIST1H2AC histone cluster 1, H2ac -0.00538684
SPINK4 serine peptidase inhibitor, Kazal type 4 -0.00538286
CD34 CD34 molecule -0.00537767
MECOM MDS1 and EVI1 complex locus -0.00535546
RHOH ras homolog family member H -0.0053536
DSTN destrin (actin depolymerizing factor) -0.00534964
NDFIP1 Nedd4 family interacting protein 1 -0.00532893
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) -0.00532574
PIGR polymeric immunoglobulin receptor -0.00530712
CXCL5 chemokine (C-X-C motif) ligand 5 -0.00529966
CXCL14 chemokine (C-X-C motif) ligand 14 -0.00529048
ISG20 interferon stimulated exonuclease gene 20kDa -0.00525425
S100A14 S100 calcium binding protein A14 -0.00524909
LGALS4 lectin, galactoside-binding, soluble, 4 -0.00524763
GPM6B glycoprotein M6B -0.00524535
CDH3 cadherin 3, type 1, P-cadherin (placental) -0.00522879
TPD52L1 tumor protein D52-like 1 -0.00521697
CAPRIN1 cell cycle associated protein 1 -0.00521467
EXPH5 exophilin 5 -0.00520186
GPX3 glutathione peroxidase 3 -0.00519328
IL33R interleukin 33 receptor -0.00518921
DEPTOR DEP domain containing MTOR-interacting protein -0.0051821
NREP neuronal regeneration related protein -0.00517907
DSP desmoplakin -0.0051775
CALML3 calmodulin-like 3 -0.00517355
ZG16 zymogen granule protein 16 -0.00514904
KRT17 keratin 17, type I -0.00514663
ITPKC inositol-trisphosphate 3-kinase C -0.00513171
TAGLN2 transgelin 2 -0.00512572
NOX1 NADPH oxidase 1 -0.00512515
STK38L serine/threonine kinase 38 like -0.00511934
MEIS1 Meis homeobox 1 -0.00510368
RASL12 RAS-like, family 12 -0.00510291
FOXF1 forkhead box F1 -0.00509594
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00508927
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide -0.0050754
SCNN1B sodium channel, non voltage gated 1 beta subunit -0.00507524
DSC2 desmocollin 2 -0.00506872
DDAH2 dimethylarginine dimethylaminohydrolase 2 -0.00506853
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -0.0050632
TMPRSS11E transmembrane protease, serine 11E -0.00505757
LAMB3 laminin, beta 3 -0.00505675
FOXG1 forkhead box G1 -0.00505466
TLK2 tousled-like kinase 2 -0.00505235