NKX2-5 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description NK2 homeobox 5|This gene encodes a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] (NCBI Entrez Gene Database, 1482)
External Link https://ncbi.nlm.nih.gov/gene/1482
Similar Terms
Downloads & Tools

Genes

498 genes differentially expressed following the NKX2-5 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
COL15A1 collagen, type XV, alpha 1 0.0185555
SPRED2 sprouty-related, EVH1 domain containing 2 0.0173891
HSPB8 heat shock 22kDa protein 8 0.0173397
MTUS1 microtubule associated tumor suppressor 1 0.0169284
APOD apolipoprotein D 0.0163136
CXCL14 chemokine (C-X-C motif) ligand 14 0.016311
RGS5 regulator of G-protein signaling 5 0.0153272
MGLL monoglyceride lipase 0.0149605
HSPA1A heat shock 70kDa protein 1A 0.0142339
MYBPC1 myosin binding protein C, slow type 0.0138311
KLF6 Kruppel-like factor 6 0.0135924
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.0135057
KRT14 keratin 14, type I 0.0133854
SCGB2A2 secretoglobin, family 2A, member 2 0.0133407
TCTA T-cell leukemia translocation altered 0.0132213
DYNLL1 dynein, light chain, LC8-type 1 0.0129882
EFHD1 EF-hand domain family, member D1 0.0128728
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.0127622
MBD1 methyl-CpG binding domain protein 1 0.0125229
DUSP5 dual specificity phosphatase 5 0.0123798
IGF1 insulin-like growth factor 1 (somatomedin C) 0.0122272
DSP desmoplakin 0.0121303
PLAAT3 phospholipase A and acyltransferase 3 0.0120275
IFI27 interferon, alpha-inducible protein 27 0.0119961
TBX3 T-box 3 0.011955
KLHL41 kelch-like family member 41 0.0119472
ACADVL acyl-CoA dehydrogenase, very long chain 0.0118487
TMEM176B transmembrane protein 176B 0.0117929
OXA1L oxidase (cytochrome c) assembly 1-like 0.0117206
ACTA1 actin, alpha 1, skeletal muscle 0.0116392
PCOLCE procollagen C-endopeptidase enhancer 0.0116039
TTN titin 0.0114731
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.0114588
AGTR1 angiotensin II receptor, type 1 0.0113734
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 0.0113462
TGFB3 transforming growth factor, beta 3 0.0113382
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) 0.0113379
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 0.0112693
ASPN asporin 0.0112689
EPB41L3 erythrocyte membrane protein band 4.1-like 3 0.0111754
ADGRF5 adhesion G protein-coupled receptor F5 0.0111611
THBS4 thrombospondin 4 0.0111085
COL14A1 collagen, type XIV, alpha 1 0.011094
PNN pinin, desmosome associated protein 0.0110413
TUBB2A tubulin, beta 2A class IIa 0.0110348
FBLN2 fibulin 2 0.0109518
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 0.0109377
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.0109312
MAOB monoamine oxidase B 0.0108677
FABP4 fatty acid binding protein 4, adipocyte 0.0108192
ISLR immunoglobulin superfamily containing leucine-rich repeat 0.0107632
DST dystonin 0.0107432
XPO7 exportin 7 0.0106543
TXLNA taxilin alpha 0.0106225
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.0104002
VCL vinculin 0.0103731
CD36 CD36 molecule (thrombospondin receptor) 0.0103531
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.010326
NAV2 neuron navigator 2 0.0102928
GOLGA8A golgin A8 family, member A 0.0102853
KRT17 keratin 17, type I 0.0102765
RRAGA Ras-related GTP binding A 0.0102705
PNISR PNN-interacting serine/arginine-rich protein 0.0102704
PLXNA1 plexin A1 0.0101092
SFN stratifin 0.0101015
RBPMS RNA binding protein with multiple splicing 0.01005
COL4A2 collagen, type IV, alpha 2 0.0100447
MTA1 metastasis associated 1 0.0100098
SASH1 SAM and SH3 domain containing 1 0.010002
CHGB chromogranin B 0.00998593
RTN2 reticulon 2 0.00996684
PERP PERP, TP53 apoptosis effector 0.00995352
MAGEA12 melanoma antigen family A12 0.00994336
ZDHHC6 zinc finger, DHHC-type containing 6 0.00983485
IGFBP4 insulin-like growth factor binding protein 4 0.00982425
RET ret proto-oncogene 0.00978023
NCOR2 nuclear receptor corepressor 2 0.00976753
SPATS2L spermatogenesis associated, serine-rich 2-like 0.0097373
RBM6 RNA binding motif protein 6 0.00966928
NPIPA1 nuclear pore complex interacting protein family, member A1 0.00964225
SEC14L1 SEC14-like 1 (S. cerevisiae) 0.00960002
MAGEA3 melanoma antigen family A3 0.00958511
TTC39A tetratricopeptide repeat domain 39A 0.00952605
MTCL1 microtubule crosslinking factor 1 0.00946394
MAP7 microtubule-associated protein 7 0.00943032
LAMB2 laminin, beta 2 (laminin S) 0.00941685
INHBB inhibin, beta B 0.00936038
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.00935855
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.00935778
LHFP lipoma HMGIC fusion partner 0.00935729
NES nestin 0.00933954
MATN2 matrilin 2 0.00933253
DIO2 deiodinase, iodothyronine, type II 0.00929956
KLF4 Kruppel-like factor 4 (gut) 0.00926693
PDZK1 PDZ domain containing 1 0.00926644
PEG10 paternally expressed 10 0.00925597
MAGEA1 melanoma antigen family A1 0.00924309
NPY1R neuropeptide Y receptor Y1 0.00919478
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 0.0091888
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 0.00918371
OGN osteoglycin 0.00916115
TM4SF1 transmembrane 4 L six family member 1 0.00911504
LASP1 LIM and SH3 protein 1 0.00908573
OSR2 odd-skipped related transciption factor 2 0.00907033
IGF1R insulin-like growth factor 1 receptor 0.00905347
SYNM synemin, intermediate filament protein 0.00900129
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 0.00898265
CKM creatine kinase, muscle 0.00897815
TNS3 tensin 3 0.00897782
MSX1 msh homeobox 1 0.00897064
CCL19 chemokine (C-C motif) ligand 19 0.00897036
RRAD Ras-related associated with diabetes 0.00896537
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 0.00889906
MFAP4 microfibrillar-associated protein 4 0.00889658
HOXC6 homeobox C6 0.00889576
CCN2 cellular communication network factor 2 0.00887573
IRS1 insulin receptor substrate 1 0.0088313
CTSA cathepsin A 0.00882821
NOTCH2NL notch 2 N-terminal like 0.00882314
SCGB1D2 secretoglobin, family 1D, member 2 0.00881295
C3 complement component 3 0.00880038
SETBP1 SET binding protein 1 0.00876633
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 0.00876024
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.00875787
PLXNB2 plexin B2 0.00864895
A2M alpha-2-macroglobulin 0.00864336
PLIN2 perilipin 2 0.00864333
PLXND1 plexin D1 0.0086328
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.00859844
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.00859728
PPAP2A phosphatidic acid phosphatase type 2A 0.00857036
COL3A1 collagen, type III, alpha 1 0.00856128
TUBB2B tubulin, beta 2B class IIb 0.00852829
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.00851707
SFRP1 secreted frizzled-related protein 1 0.00848971
LUM lumican 0.00848916
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 0.0084579
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.008456
ASS1 argininosuccinate synthase 1 0.00841417
ACTN4 actinin, alpha 4 0.00841011
SPON2 spondin 2, extracellular matrix protein 0.00840993
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00840019
GLA galactosidase, alpha 0.00837114
MVP major vault protein 0.00835998
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 0.00834106
ADRA2A adrenoceptor alpha 2A 0.00832875
TENT5A terminal nucleotidyltransferase 5A 0.00831933
NID1 nidogen 1 0.00831765
KLC1 kinesin light chain 1 0.00831356
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.00824255
CXCL13 chemokine (C-X-C motif) ligand 13 0.00824098
ENO3 enolase 3 (beta, muscle) 0.00822749
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.00822645
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.00822124
AHNAK AHNAK nucleoprotein 0.00820146
COL5A1 collagen, type V, alpha 1 0.0081726
TNNI1 troponin I type 1 (skeletal, slow) 0.00817259
ANO1 anoctamin 1, calcium activated chloride channel 0.00816698
TNNC2 troponin C type 2 (fast) 0.00816133
NFIB nuclear factor I/B 0.00816133
PDGFRL platelet-derived growth factor receptor-like 0.00814465
RBM26 RNA binding motif protein 26 0.00814075
FAM50A family with sequence similarity 50, member A 0.00813727
TNNC1 troponin C type 1 (slow) 0.00813149
MGP matrix Gla protein 0.00812658
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 0.00812324
MLXIP MLX interacting protein 0.00810339
DAAM2 dishevelled associated activator of morphogenesis 2 0.00806694
BHMT2 betaine--homocysteine S-methyltransferase 2 0.00805714
TUBB6 tubulin, beta 6 class V 0.00805231
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 0.00804015
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.00803781
PDGFD platelet derived growth factor D 0.00800114
CDH5 cadherin 5, type 2 (vascular endothelium) 0.00799869
TPM3 tropomyosin 3 0.00797485
RUNX3 runt-related transcription factor 3 0.00796452
DMTF1 cyclin D binding myb-like transcription factor 1 0.00796053
MYOT myotilin 0.00793489
VWF von Willebrand factor 0.00791715
SLIT2 slit homolog 2 (Drosophila) 0.00791568
AMOTL2 angiomotin like 2 0.00791394
TWIST1 twist family bHLH transcription factor 1 0.00790178
COL4A1 collagen, type IV, alpha 1 0.00789427
CRCT1 cysteine-rich C-terminal 1 0.00788439
TP53BP2 tumor protein p53 binding protein 2 0.00788084
FXR1 fragile X mental retardation, autosomal homolog 1 0.00783574
MITF microphthalmia-associated transcription factor 0.00783212
AMDHD2 amidohydrolase domain containing 2 0.00783131
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 0.00782902
RBM25 RNA binding motif protein 25 0.00782043
IL11RA interleukin 11 receptor, alpha 0.00781469
MYL1 myosin, light chain 1, alkali; skeletal, fast 0.00781361
FAM189A2 family with sequence similarity 189, member A2 0.00779108
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.00778579
SAMD4A sterile alpha motif domain containing 4A 0.00777445
OLFM1 olfactomedin 1 0.00776355
FMO2 flavin containing monooxygenase 2 (non-functional) 0.00775937
STK10 serine/threonine kinase 10 0.00773209
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 0.00773026
AKR1C3 aldo-keto reductase family 1, member C3 0.00772582
COQ8A coenzyme Q8A 0.00771363
HMBOX1 homeobox containing 1 0.00771292
PMP22 peripheral myelin protein 22 0.00771031
IST1 increased sodium tolerance 1 homolog (yeast) 0.00770142
HMOX1 heme oxygenase 1 0.00769016
EGR1 early growth response 1 0.00767485
IER5 immediate early response 5 0.00767297
PIGG phosphatidylinositol glycan anchor biosynthesis, class G 0.00765034
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 0.00763319
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 0.00762583
ADGRG2 adhesion G protein-coupled receptor G2 0.00760002
MMP3 matrix metallopeptidase 3 0.00759008
PDK4 pyruvate dehydrogenase kinase, isozyme 4 0.00758163
FAM110B family with sequence similarity 110, member B 0.00758136
PCSK5 proprotein convertase subtilisin/kexin type 5 0.00757378
GAA glucosidase, alpha; acid 0.00756721
PLPP2 phospholipid phosphatase 2 0.00756507
GAL galanin/GMAP prepropeptide 0.00755706
CXCL2 chemokine (C-X-C motif) ligand 2 0.007555
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.00754765
IL32 interleukin 32 0.00754481
CTSL cathepsin L 0.00753363
ITPKB inositol-trisphosphate 3-kinase B 0.00753029
RABEP2 rabaptin, RAB GTPase binding effector protein 2 0.00752753
TIMP3 TIMP metallopeptidase inhibitor 3 0.00752503
MYOF myoferlin 0.00752419
SPRR2B small proline-rich protein 2B 0.00752398
GOLGB1 golgin B1 0.00750813
DKFZP586I1420 uncharacterized protein DKFZp586I1420 0.00749226
LAMA2 laminin, alpha 2 0.00747703
KPNB1 karyopherin (importin) beta 1 0.0074661
MFSD10 major facilitator superfamily domain containing 10 0.00744723
SIGMAR1 sigma non-opioid intracellular receptor 1 0.0074365
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.00743509
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.00742926
NKTR natural killer cell triggering receptor 0.00742648
CEMIP2 cell migration inducing hyaluronidase 2 0.00742566
ITGB5 integrin, beta 5 0.0074186
STX16 syntaxin 16 0.00741557
GOLGA8H golgin A8 family, member H 0.00741025
SQSTM1 sequestosome 1 0.00740684
OPHN1 oligophrenin 1 0.00740448
APOLD1 apolipoprotein L domain containing 1 0.00736087
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.0073603
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.00734821
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 0.00734425
CD248 CD248 molecule, endosialin 0.00733688
NUCLEOLIN nucleolin multifunctional protein 0.00731776
METTL3 methyltransferase like 3 0.00731521

decreased expression

Symbol Name Standardized Value
S100A8 S100 calcium binding protein A8 -0.0223327
LTF lactotransferrin -0.0197785
S100A9 S100 calcium binding protein A9 -0.0196729
LCN2 lipocalin 2 -0.0190337
PCP4 Purkinje cell protein 4 -0.0180919
HBB hemoglobin, beta -0.0155922
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.0155153
ENC1 ectodermal-neural cortex 1 (with BTB domain) -0.0153582
OLFM4 olfactomedin 4 -0.015188
NRGN neurogranin (protein kinase C substrate, RC3) -0.0149846
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.0145332
DEFA4 defensin, alpha 4, corticostatin -0.0140178
CSTA cystatin A (stefin A) -0.0138366
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) -0.0136739
METRN meteorin, glial cell differentiation regulator -0.0136417
IFITM1 interferon induced transmembrane protein 1 -0.0135294
CD9 CD9 molecule -0.0135073
PLBD1 phospholipase B domain containing 1 -0.0133096
S100A12 S100 calcium binding protein A12 -0.0131186
FOLR1 folate receptor 1 (adult) -0.0127974
CAMP cathelicidin antimicrobial peptide -0.0125317
SRGN serglycin -0.0124323
PRKACB protein kinase, cAMP-dependent, catalytic, beta -0.0123942
LY96 lymphocyte antigen 96 -0.0123898
HBD hemoglobin, delta -0.0123282
CDH3 cadherin 3, type 1, P-cadherin (placental) -0.0121015
CEMIP cell migration inducing protein, hyaluronan binding -0.0119309
EVI2A ecotropic viral integration site 2A -0.0118548
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 -0.0118131
TXNDC9 thioredoxin domain containing 9 -0.0117273
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.0115634
CLC Charcot-Leyden crystal galectin -0.011474
FAM171A1 family with sequence similarity 171, member A1 -0.0114481
CCNA1 cyclin A1 -0.0114117
BPI bactericidal/permeability-increasing protein -0.0111952
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 -0.0111765
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -0.0111702
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.0110946
MMP9 matrix metallopeptidase 9 -0.0110172
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) -0.0110094
LST1 leukocyte specific transcript 1 -0.0109595
SYNGR3 synaptogyrin 3 -0.0109292
SNCA synuclein, alpha (non A4 component of amyloid precursor) -0.0108724
KLRB1 killer cell lectin-like receptor subfamily B, member 1 -0.0107858
MCUB mitochondrial calcium uniporter dominant negative subunit beta -0.0107585
TARP TCR gamma alternate reading frame protein -0.0104859
RGS10 regulator of G-protein signaling 10 -0.0104706
CTSS cathepsin S -0.0103361
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.010303
LYZ lysozyme -0.0102855
SCG5 secretogranin V -0.0102829
CD52 CD52 molecule -0.0102234
FCN1 ficolin (collagen/fibrinogen domain containing) 1 -0.010195
CD48 CD48 molecule -0.0101804
NMU neuromedin U -0.0101597
RNASE3 ribonuclease, RNase A family, 3 -0.0101273
C12ORF29 chromosome 12 open reading frame 29 -0.0100663
CRYM crystallin, mu -0.0100217
JCHAIN joining chain of multimeric IgA and IgM -0.00996764
MNDA myeloid cell nuclear differentiation antigen -0.00995231
MGAM maltase-glucoamylase -0.00986669
ELANE elastase, neutrophil expressed -0.00986505
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits -0.00983005
FPR1 formyl peptide receptor 1 -0.00974575
GCHFR GTP cyclohydrolase I feedback regulator -0.00969261
RNASE6 ribonuclease, RNase A family, k6 -0.00962111
APOC1 apolipoprotein C-I -0.00959928
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae) -0.00958174
MAL mal, T-cell differentiation protein -0.0094005
KRCC1 lysine-rich coiled-coil 1 -0.00939618
C1ORF54 chromosome 1 open reading frame 54 -0.00939424
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 -0.00938993
ENO2 enolase 2 (gamma, neuronal) -0.00937685
SV2A synaptic vesicle glycoprotein 2A -0.00935853
VBP1 von Hippel-Lindau binding protein 1 -0.00932709
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 -0.00926756
RPS5 ribosomal protein S5 -0.00925074
CST7 cystatin F (leukocystatin) -0.00924543
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) -0.00919984
TMEM14B transmembrane protein 14B -0.00918734
DCK deoxycytidine kinase -0.00915236
WFDC2 WAP four-disulfide core domain 2 -0.00915213
EFHC2 EF-hand domain (C-terminal) containing 2 -0.00913623
EAPP E2F-associated phosphoprotein -0.00911054
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -0.00910878
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00910421
CYBB cytochrome b-245, beta polypeptide -0.00901761
LPAR6 lysophosphatidic acid receptor 6 -0.00898656
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) -0.00897885
PF4 platelet factor 4 -0.00892983
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.00892434
COMMD8 COMM domain containing 8 -0.00889835
KRT19 keratin 19, type I -0.00887134
GCA grancalcin, EF-hand calcium binding protein -0.00884224
CDCA4 cell division cycle associated 4 -0.00880306
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -0.008787
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -0.00875856
ANO3 anoctamin 3 -0.00875067
MMP8 matrix metallopeptidase 8 -0.00874156
S100P S100 calcium binding protein P -0.00870341
AKAP8 A kinase (PRKA) anchor protein 8 -0.00865894
SPTSSA serine palmitoyltransferase, small subunit A -0.00855474
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.00853009
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -0.00848803
PPA2 pyrophosphatase (inorganic) 2 -0.008469
NPM3 nucleophosmin/nucleoplasmin 3 -0.00846523
GPR65 G protein-coupled receptor 65 -0.00843362
PGLYRP1 peptidoglycan recognition protein 1 -0.00841822
CD2 CD2 molecule -0.00840901
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) -0.00840548
ADI1 acireductone dioxygenase 1 -0.00839023
FKBP1B FK506 binding protein 1B, 12.6 kDa -0.00838545
IFT57 intraflagellar transport 57 -0.00835462
RNF130 ring finger protein 130 -0.00835284
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -0.00832051
CCNA2 cyclin A2 -0.00831496
DHRS3 dehydrogenase/reductase (SDR family) member 3 -0.00831122
IL7R interleukin 7 receptor -0.00827585
CXCR4 chemokine (C-X-C motif) receptor 4 -0.00826797
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.00826642
NR1D2 nuclear receptor subfamily 1, group D, member 2 -0.00814764
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) -0.00813449
FABP6 fatty acid binding protein 6, ileal -0.00812327
TYROBP TYRO protein tyrosine kinase binding protein -0.00811773
NMT2 N-myristoyltransferase 2 -0.00811693
PDIA3 protein disulfide isomerase family A, member 3 -0.00809522
GNLY granulysin -0.00809241
NIPSNAP2 nipsnap homolog 2 -0.00808715
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.00807845
TEX10 testis expressed 10 -0.00807688
BCL2A1 BCL2-related protein A1 -0.00807388
FOS FBJ murine osteosarcoma viral oncogene homolog -0.00804679
COPS4 COP9 signalosome subunit 4 -0.00804169
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.00801643
SEC23A Sec23 homolog A (S. cerevisiae) -0.00800991
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 -0.00800185
RSBN1 round spermatid basic protein 1 -0.00800052
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 -0.00799689
GNG10 guanine nucleotide binding protein (G protein), gamma 10 -0.00799243
CLEC5A C-type lectin domain family 5, member A -0.00798103
POLB polymerase (DNA directed), beta -0.00796962
CHIT1 chitinase 1 (chitotriosidase) -0.00792962
CEP70 centrosomal protein 70kDa -0.00792431
MECOM MDS1 and EVI1 complex locus -0.00788436
MSLN mesothelin -0.00786197
HTRA1 HtrA serine peptidase 1 -0.00785947
MAGEH1 melanoma antigen family H1 -0.00785377
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) -0.00784346
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G -0.00783602
TSPAN31 tetraspanin 31 -0.00782802
TCEAL2 transcription elongation factor A (SII)-like 2 -0.00781627
IFITM3 interferon induced transmembrane protein 3 -0.00776189
CCL5 chemokine (C-C motif) ligand 5 -0.00774278
NUSAP1 nucleolar and spindle associated protein 1 -0.00773137
TCEAL1 transcription elongation factor A (SII)-like 1 -0.00770623
STK38L serine/threonine kinase 38 like -0.0077038
MPO myeloperoxidase -0.00768607
BST1 bone marrow stromal cell antigen 1 -0.00768196
CD300A CD300a molecule -0.00767993
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -0.00767639
IFT52 intraflagellar transport 52 -0.00767513
AIF1 allograft inflammatory factor 1 -0.00764025
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -0.00761944
IL2RG interleukin 2 receptor, gamma -0.00761092
AHSP alpha hemoglobin stabilizing protein -0.00759238
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 -0.00758485
THAP1 THAP domain containing, apoptosis associated protein 1 -0.00757781
ACTR3 ARP3 actin-related protein 3 homolog (yeast) -0.00752553
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -0.00750696
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein -0.00747106
CRYL1 crystallin, lambda 1 -0.00747093
ACP3 acid phosphatase 3 -0.00746926
ATF1 activating transcription factor 1 -0.00745562
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.00743955
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 -0.007397
CTBS chitobiase, di-N-acetyl- -0.00739144
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 -0.0073786
HSPA13 heat shock protein 70kDa family, member 13 -0.00737734
CLEC2B C-type lectin domain family 2, member B -0.00736889
ATP10B ATPase, class V, type 10B -0.00736885
ESR1 estrogen receptor 1 -0.00736341
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide -0.0073617
EPHA4 EPH receptor A4 -0.00735487
PADI2 peptidyl arginine deiminase, type II -0.00733931
TP53TG1 TP53 target 1 (non-protein coding) -0.00733763
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -0.00732188
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00731214
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -0.00730298
CETN2 centrin, EF-hand protein, 2 -0.0072965
SINHCAF SIN3-HDAC complex associated factor -0.00729147
GTPBP8 GTP-binding protein 8 (putative) -0.00728883
MED28 mediator complex subunit 28 -0.00727619
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.00726018
SLC44A4 solute carrier family 44, member 4 -0.00725961
DPYD dihydropyrimidine dehydrogenase -0.00725926
NME4 NME/NM23 nucleoside diphosphate kinase 4 -0.0072216
TMEM106B transmembrane protein 106B -0.00721303
XCL1 chemokine (C motif) ligand 1 -0.0072049
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -0.00719225
GPN1 GPN-loop GTPase 1 -0.00715055
TMX1 thioredoxin-related transmembrane protein 1 -0.0071354
ZNF274 zinc finger protein 274 -0.00711914
GOLPH3L golgi phosphoprotein 3-like -0.00711736
CD8A CD8a molecule -0.00710447
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) -0.00708107
ADORA2B adenosine A2b receptor -0.00707848
MAGT1 magnesium transporter 1 -0.00706649
HDAC9 histone deacetylase 9 -0.00706574
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00706114
ALAS2 5'-aminolevulinate synthase 2 -0.00705503
PFDN5 prefoldin subunit 5 -0.00703993
KRT13 keratin 13, type I -0.00703529
FXYD3 FXYD domain containing ion transport regulator 3 -0.00703479
SCN3A sodium channel, voltage gated, type III alpha subunit -0.00700515
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor -0.00699709
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic -0.00699287
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) -0.00698831
MZB1 marginal zone B and B1 cell-specific protein -0.00698165
CLINT1 clathrin interactor 1 -0.00698158
CENPU centromere protein U -0.00697182
TPM4 tropomyosin 4 -0.00696474
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 -0.00696164
IFT46 intraflagellar transport 46 -0.00694297
FOLR3 folate receptor 3 (gamma) -0.00693162
NKG7 natural killer cell granule protein 7 -0.00692174
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) -0.00690531
ALOX5 arachidonate 5-lipoxygenase -0.00690487
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 -0.00689007
OSBPL8 oxysterol binding protein-like 8 -0.00688893
PHACTR1 phosphatase and actin regulator 1 -0.00688829
IL18RAP interleukin 18 receptor accessory protein -0.00688228
RESF1 retroelement silencing factor 1 -0.00686677
IDI1 isopentenyl-diphosphate delta isomerase 1 -0.00686414
SELENBP1 selenium binding protein 1 -0.00685025
DSCC1 DNA replication and sister chromatid cohesion 1 -0.00684974
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.00683953
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -0.00683951
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme -0.00683821
MLF1 myeloid leukemia factor 1 -0.0068214
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.00681573
APIP APAF1 interacting protein -0.00681081
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -0.0068021
GLIPR1 GLI pathogenesis-related 1 -0.00678914
AQP9 aquaporin 9 -0.00678618
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.00678067
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 -0.00677966
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) -0.00677343
MSMO1 methylsterol monooxygenase 1 -0.00676614
ZNF395 zinc finger protein 395 -0.00676056