NKX2-6 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description NK2 homeobox 6 (NCBI Entrez Gene Database, 137814)
External Link https://ncbi.nlm.nih.gov/gene/137814
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Genes

499 genes differentially expressed following the NKX2-6 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
BEX1 brain expressed, X-linked 1 0.0155311
XPO7 exportin 7 0.0141206
RGS5 regulator of G-protein signaling 5 0.012696
OLFM1 olfactomedin 1 0.0123085
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 0.0121956
TENT5A terminal nucleotidyltransferase 5A 0.0121683
SPRED2 sprouty-related, EVH1 domain containing 2 0.0118222
FHL1 four and a half LIM domains 1 0.0118082
CAV1 caveolin 1, caveolae protein, 22kDa 0.0117518
CADM1 cell adhesion molecule 1 0.0111433
FABP7 fatty acid binding protein 7, brain 0.0111108
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.0108887
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.0108614
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa 0.0104567
COQ8A coenzyme Q8A 0.0103169
GAP43 growth associated protein 43 0.00998122
EDNRB endothelin receptor type B 0.00995698
APOLD1 apolipoprotein L domain containing 1 0.0099025
BCAT1 branched chain amino-acid transaminase 1, cytosolic 0.00985736
MATN2 matrilin 2 0.00983465
SRSF1 serine/arginine-rich splicing factor 1 0.00947898
PCSK1 proprotein convertase subtilisin/kexin type 1 0.0094197
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.00924599
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 0.00911976
SPARCL1 SPARC-like 1 (hevin) 0.00900728
ACTB actin, beta 0.00899323
FGF13 fibroblast growth factor 13 0.00888885
DMAC2L distal membrane arm assembly component 2 like 0.00883895
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.00882696
ADAT1 adenosine deaminase, tRNA-specific 1 0.00875374
TYRP1 tyrosinase-related protein 1 0.00869362
NES nestin 0.00860687
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.00857183
PLS3 plastin 3 0.00856494
TUBB2B tubulin, beta 2B class IIb 0.00854681
CAV2 caveolin 2 0.00850863
OXA1L oxidase (cytochrome c) assembly 1-like 0.00839255
MEN1 multiple endocrine neoplasia I 0.00838344
PBK PDZ binding kinase 0.00838017
KIF23 kinesin family member 23 0.00826986
AKAP8 A kinase (PRKA) anchor protein 8 0.00823412
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.0082174
CD93 CD93 molecule 0.00817761
EXOC5 exocyst complex component 5 0.00816237
SNX7 sorting nexin 7 0.00813982
PRDX2 peroxiredoxin 2 0.00811461
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.00811107
SHCBP1 SHC SH2-domain binding protein 1 0.00810184
PLP1 proteolipid protein 1 0.00809298
ITM2A integral membrane protein 2A 0.00803761
DMD dystrophin 0.00799775
AQP1 aquaporin 1 (Colton blood group) 0.00798667
S100B S100 calcium binding protein B 0.00793112
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.00791655
SPRY2 sprouty homolog 2 (Drosophila) 0.00790795
TOX thymocyte selection-associated high mobility group box 0.00785986
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.00785288
CXCL14 chemokine (C-X-C motif) ligand 14 0.00782919
TRIM9 tripartite motif containing 9 0.00779755
HSPB8 heat shock 22kDa protein 8 0.0077127
PFDN4 prefoldin subunit 4 0.00769688
SAMD4A sterile alpha motif domain containing 4A 0.00768308
NRN1 neuritin 1 0.00766157
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.00761047
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) 0.00754817
RBBP4 retinoblastoma binding protein 4 0.00754354
TIGAR TP53 induced glycolysis regulatory phosphatase 0.00743497
PIGC phosphatidylinositol glycan anchor biosynthesis, class C 0.00743248
SPC25 SPC25, NDC80 kinetochore complex component 0.00742565
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene) 0.00741098
L1TD1 LINE-1 type transposase domain containing 1 0.00734993
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 0.00728305
NOTCH2NL notch 2 N-terminal like 0.00722922
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.00722349
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 0.00721265
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0071958
COX7B cytochrome c oxidase subunit VIIb 0.00717835
ADGRF5 adhesion G protein-coupled receptor F5 0.00716378
TSPAN7 tetraspanin 7 0.00714989
ADGRG2 adhesion G protein-coupled receptor G2 0.00713031
HMBOX1 homeobox containing 1 0.00712751
MRPS28 mitochondrial ribosomal protein S28 0.00712486
EDIL3 EGF-like repeats and discoidin I-like domains 3 0.00709276
FABP4 fatty acid binding protein 4, adipocyte 0.00708846
THBD thrombomodulin 0.0070795
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 0.00702546
LAPTM4B lysosomal protein transmembrane 4 beta 0.00702002
PPP2R2B protein phosphatase 2, regulatory subunit B, beta 0.0070111
TRAM1 translocation associated membrane protein 1 0.00694215
EMP2 epithelial membrane protein 2 0.00692837
TCTA T-cell leukemia translocation altered 0.00691283
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 0.00690624
EML4 echinoderm microtubule associated protein like 4 0.00688529
CPE carboxypeptidase E 0.00687157
ATAD2 ATPase family, AAA domain containing 2 0.00681383
KLHL7 kelch-like family member 7 0.00681317
DCTN4 dynactin 4 (p62) 0.00678692
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.0067789
JAM2 junctional adhesion molecule 2 0.00675403
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.00670765
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00667058
PDGFD platelet derived growth factor D 0.00665983
PLN phospholamban 0.00664596
CXCL12 chemokine (C-X-C motif) ligand 12 0.00663441
RBMS1 RNA binding motif, single stranded interacting protein 1 0.00661698
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.00660744
DYNLL1 dynein, light chain, LC8-type 1 0.00659679
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.00656816
EPB41L3 erythrocyte membrane protein band 4.1-like 3 0.00656532
MFSD10 major facilitator superfamily domain containing 10 0.00653445
SORBS1 sorbin and SH3 domain containing 1 0.00652029
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 0.00651014
PDZD2 PDZ domain containing 2 0.00649767
PTHLH parathyroid hormone-like hormone 0.00648955
LMO2 LIM domain only 2 (rhombotin-like 1) 0.00648818
SEPP1 selenoprotein P, plasma, 1 0.00647793
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.00647176
CDH5 cadherin 5, type 2 (vascular endothelium) 0.0064534
FZD3 frizzled class receptor 3 0.00644161
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 0.00640016
FBXO5 F-box protein 5 0.00638801
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 0.00637103
RNFT1 ring finger protein, transmembrane 1 0.00636632
MCAM melanoma cell adhesion molecule 0.00636227
KBTBD11 kelch repeat and BTB (POZ) domain containing 11 0.00636178
ACE2 angiotensin I converting enzyme 2 0.00633728
PLLP plasmolipin 0.00632657
KIF18A kinesin family member 18A 0.00630399
ENSA endosulfine alpha 0.00628489
RTN2 reticulon 2 0.0062763
LYRM2 LYR motif containing 2 0.00626038
TPM3 tropomyosin 3 0.00625719
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.00624628
CSE1L CSE1 chromosome segregation 1-like (yeast) 0.00623497
C8ORF33 chromosome 8 open reading frame 33 0.00622971
CLIC5 chloride intracellular channel 5 0.00621258
FCGBP Fc fragment of IgG binding protein 0.00619798
GUSBP3 glucuronidase, beta pseudogene 3 0.00619624
DCHS1 dachsous cadherin-related 1 0.00617579
SELE selectin E 0.00616707
MAB21L2 mab-21-like 2 (C. elegans) 0.00616168
ANOS1 anosmin 1 0.0061454
TMEM230 transmembrane protein 230 0.00614056
GAB2 GRB2-associated binding protein 2 0.0061396
TUBB2A tubulin, beta 2A class IIa 0.00612623
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 0.00607588
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.00607231
ADGRL2 adhesion G protein-coupled receptor L2 0.00607176
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.0060685
SGPP1 sphingosine-1-phosphate phosphatase 1 0.00604715
RAD51AP1 RAD51 associated protein 1 0.00603898
SUMO3 small ubiquitin-like modifier 3 0.00602451
PRNP prion protein 0.00601056
EDN3 endothelin 3 0.00600987
GNA13 guanine nucleotide binding protein (G protein), alpha 13 0.00599092
SYNGR3 synaptogyrin 3 0.00597992
VANGL1 VANGL planar cell polarity protein 1 0.00597125
TAC1 tachykinin, precursor 1 0.00596978
CALCA calcitonin-related polypeptide alpha 0.00596322
RET ret proto-oncogene 0.00596075
FAR2 fatty acyl CoA reductase 2 0.00596023
KIF14 kinesin family member 14 0.0059586
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 0.00595789
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.00595284
COMMD10 COMM domain containing 10 0.00593176
VWF von Willebrand factor 0.00592784
GPC3 glypican 3 0.00592372
SCAMP1 secretory carrier membrane protein 1 0.00591871
CHEK1 checkpoint kinase 1 0.00591806
PRIM2 primase, DNA, polypeptide 2 (58kDa) 0.0059038
VCL vinculin 0.00585431
RNF125 ring finger protein 125, E3 ubiquitin protein ligase 0.00585061
NAP1L2 nucleosome assembly protein 1-like 2 0.0058452
SKA1 spindle and kinetochore associated complex subunit 1 0.00584323
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.00583451
MARCHF7 membrane associated ring-CH-type finger 7 0.00582687
CDCA3 cell division cycle associated 3 0.00582625
TARBP1 TAR (HIV-1) RNA binding protein 1 0.00582242
HOPX HOP homeobox 0.0057955
COPS7A COP9 signalosome subunit 7A 0.00579325
TGFBR3 transforming growth factor, beta receptor III 0.00578898
SEPTIN10 septin 10 0.00576804
TIMP4 TIMP metallopeptidase inhibitor 4 0.0057644
CYC1 cytochrome c-1 0.00575851
GOLGA8A golgin A8 family, member A 0.00574556
ZNF207 zinc finger protein 207 0.00574359
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 0.0057403
FRY furry homolog (Drosophila) 0.00573682
TNNC1 troponin C type 1 (slow) 0.00573535
TAGLN2 transgelin 2 0.00573246
TFDP1 transcription factor Dp-1 0.00569569
MYO1B myosin IB 0.00568754
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.00568101
CAMTA1 calmodulin binding transcription activator 1 0.00568031
RPL10 ribosomal protein L10 0.00567694
GATA6 GATA binding protein 6 0.00567177
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.00566207
YIPF5 Yip1 domain family, member 5 0.00563111
ARHGAP29 Rho GTPase activating protein 29 0.00562888
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.00562828
MGP matrix Gla protein 0.00561763
TSPAN13 tetraspanin 13 0.00559831
PTH2R parathyroid hormone 2 receptor 0.00559143
NXPE3 neurexophilin and PC-esterase domain family, member 3 0.00557631
CXADR coxsackie virus and adenovirus receptor 0.00555001
NLGN4X neuroligin 4, X-linked 0.00554818
MMP3 matrix metallopeptidase 3 0.00553865
SACS sacsin molecular chaperone 0.00553715
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.00553384
ITGA6 integrin, alpha 6 0.00553353
REG3A regenerating islet-derived 3 alpha 0.00552678
MSN moesin 0.00552648
NOLC1 nucleolar and coiled-body phosphoprotein 1 0.00552427
GPA33 glycoprotein A33 (transmembrane) 0.00552407
MEOX1 mesenchyme homeobox 1 0.00551897
PHIP pleckstrin homology domain interacting protein 0.0055118
FZD5 frizzled class receptor 5 0.00550878
E2F8 E2F transcription factor 8 0.005504
ACTG2 actin, gamma 2, smooth muscle, enteric 0.00550305
C3ORF14 chromosome 3 open reading frame 14 0.00550111
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.00548711
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 0.00548446
MRPS33 mitochondrial ribosomal protein S33 0.00546449
ARHGAP32 Rho GTPase activating protein 32 0.00546387
MARCKS myristoylated alanine-rich protein kinase C substrate 0.00546288
COL9A3 collagen, type IX, alpha 3 0.00545932
CLCA1 chloride channel accessory 1 0.00545263
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.00545115
EGR2 early growth response 2 0.00544715
WIF1 WNT inhibitory factor 1 0.00544266
TACC1 transforming, acidic coiled-coil containing protein 1 0.0054375
S100A10 S100 calcium binding protein A10 0.00543642
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease 0.00543167
RASA4 RAS p21 protein activator 4 0.00543054
SNX10 sorting nexin 10 0.00542232
IRX5 iroquois homeobox 5 0.00542017
ANXA2 annexin A2 0.00540973
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 0.00540686
PTPRB protein tyrosine phosphatase, receptor type, B 0.00540114
WWTR1 WW domain containing transcription regulator 1 0.00539569
SYNM synemin, intermediate filament protein 0.00539444
PMP2 peripheral myelin protein 2 0.00538651
LHFP lipoma HMGIC fusion partner 0.0053736
OGN osteoglycin 0.00534153
MYOZ2 myozenin 2 0.0053407
NEFH neurofilament, heavy polypeptide 0.00533848
MTUS1 microtubule associated tumor suppressor 1 0.00532009
PSAT1 phosphoserine aminotransferase 1 0.00531983
NOVA1 neuro-oncological ventral antigen 1 0.00531945
PTK2 protein tyrosine kinase 2 0.00530969

decreased expression

Symbol Name Standardized Value
LTF lactotransferrin -0.018062
CA12 carbonic anhydrase XII -0.0144797
LCN2 lipocalin 2 -0.0140697
CD9 CD9 molecule -0.0138257
SSBP2 single-stranded DNA binding protein 2 -0.0132519
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.0131296
WDR7 WD repeat domain 7 -0.0128855
MLPH melanophilin -0.0127754
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.0127226
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.0125332
MMP9 matrix metallopeptidase 9 -0.0124193
AEBP1 AE binding protein 1 -0.011606
BLNK B-cell linker -0.0114926
POU2AF1 POU class 2 associating factor 1 -0.0113935
CDC20 cell division cycle 20 -0.0112051
INHBA inhibin, beta A -0.0109334
KRT15 keratin 15, type I -0.0108023
H1-2 H1.2 linker histone, cluster member -0.0107855
ZFP36L1 ZFP36 ring finger protein-like 1 -0.0103796
SAT1 spermidine/spermine N1-acetyltransferase 1 -0.0102019
CD52 CD52 molecule -0.0100923
NBL1 neuroblastoma 1, DAN family BMP antagonist -0.00985782
TCL1A T-cell leukemia/lymphoma 1A -0.00985353
S100A9 S100 calcium binding protein A9 -0.00984175
NUPR1 nuclear protein, transcriptional regulator, 1 -0.00982648
NT5E 5'-nucleotidase, ecto (CD73) -0.00976206
MMP7 matrix metallopeptidase 7 -0.00975827
VPREB3 pre-B lymphocyte 3 -0.00970401
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.00950684
OSBPL8 oxysterol binding protein-like 8 -0.00924451
S100A8 S100 calcium binding protein A8 -0.00919323
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00916367
CRYM crystallin, mu -0.00914367
FTH1 ferritin, heavy polypeptide 1 -0.00901889
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) -0.00896427
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -0.00894594
IL1RN interleukin 1 receptor antagonist -0.00891893
KRT5 keratin 5, type II -0.00882159
MMP11 matrix metallopeptidase 11 -0.00881701
LRRC15 leucine rich repeat containing 15 -0.00880707
S100A2 S100 calcium binding protein A2 -0.00876409
NKX3-1 NK3 homeobox 1 -0.00869098
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.00862071
LEF1 lymphoid enhancer-binding factor 1 -0.00861002
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -0.00855066
DSP desmoplakin -0.00842725
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 -0.00839867
MZB1 marginal zone B and B1 cell-specific protein -0.00839082
MSMB microseminoprotein, beta- -0.00838744
HOXB2 homeobox B2 -0.00836198
PLBD1 phospholipase B domain containing 1 -0.00832372
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.00831245
MT1G metallothionein 1G -0.00821765
CD19 CD19 molecule -0.00820434
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.00817086
SORBS2 sorbin and SH3 domain containing 2 -0.00815646
PAX5 paired box 5 -0.00814253
IFI30 interferon, gamma-inducible protein 30 -0.00813899
CYFIP2 cytoplasmic FMR1 interacting protein 2 -0.00811516
CD40 CD40 molecule, TNF receptor superfamily member 5 -0.00810985
IPO13 importin 13 -0.00809207
TYMP thymidine phosphorylase -0.00808973
SCPEP1 serine carboxypeptidase 1 -0.00807823
SLC44A4 solute carrier family 44, member 4 -0.00804125
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 -0.00796065
CYBB cytochrome b-245, beta polypeptide -0.00790082
IKZF1 IKAROS family zinc finger 1 (Ikaros) -0.00789352
CCNA1 cyclin A1 -0.0078873
GREM1 gremlin 1, DAN family BMP antagonist -0.00787999
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.00787079
IL7R interleukin 7 receptor -0.00786363
KRT23 keratin 23, type I -0.00786118
TPSAB1 tryptase alpha/beta 1 -0.00781219
ADM adrenomedullin -0.00780394
LOXL1 lysyl oxidase-like 1 -0.00779885
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 -0.00776903
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00761917
TMC5 transmembrane channel-like 5 -0.00760334
CAMP cathelicidin antimicrobial peptide -0.00756089
BLVRB biliverdin reductase B -0.00755663
DLK1 delta-like 1 homolog (Drosophila) -0.00755218
CD79A CD79a molecule, immunoglobulin-associated alpha -0.00754346
COL10A1 collagen, type X, alpha 1 -0.00754288
COL6A3 collagen, type VI, alpha 3 -0.00751442
ENC1 ectodermal-neural cortex 1 (with BTB domain) -0.00747018
H1-0 H1.0 linker histone -0.00745621
HTRA1 HtrA serine peptidase 1 -0.00735351
PRKACB protein kinase, cAMP-dependent, catalytic, beta -0.00734509
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -0.00732509
EYA2 EYA transcriptional coactivator and phosphatase 2 -0.00729561
TNIP1 TNFAIP3 interacting protein 1 -0.00726141
WASHC4 WASH complex subunit 4 -0.00723808
ATP2A3 ATPase, Ca++ transporting, ubiquitous -0.00722729
RRAGD Ras-related GTP binding D -0.00721522
ISG20 interferon stimulated exonuclease gene 20kDa -0.0072101
APOL1 apolipoprotein L, 1 -0.00713986
TOB1 transducer of ERBB2, 1 -0.00710684
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00710544
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.00710152
ACTN1 actinin, alpha 1 -0.00706455
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) -0.0070462
KYNU kynureninase -0.00704345
KRT19 keratin 19, type I -0.00704283
CTSB cathepsin B -0.00699974
CTSD cathepsin D -0.00679981
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa -0.00679968
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00679268
CRISP3 cysteine-rich secretory protein 3 -0.00678518
GADD45A growth arrest and DNA-damage-inducible, alpha -0.00670865
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -0.00670846
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.00670468
MT1X metallothionein 1X -0.00668863
UPK1B uroplakin 1B -0.00667444
CLTB clathrin, light chain B -0.00666173
S100A12 S100 calcium binding protein A12 -0.00665817
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha -0.00664342
IGFBP1 insulin-like growth factor binding protein 1 -0.00659171
BGN biglycan -0.00657631
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00655792
KRT16 keratin 16, type I -0.00654654
FOXJ1 forkhead box J1 -0.00652102
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 -0.00649735
IGLL1 immunoglobulin lambda-like polypeptide 1 -0.00649439
PPP1R3C protein phosphatase 1, regulatory subunit 3C -0.00648986
F5 coagulation factor V (proaccelerin, labile factor) -0.00648435
GSDME gasdermin E -0.00645737
SIDT2 SID1 transmembrane family, member 2 -0.00645538
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits -0.00645084
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.00643971
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -0.00639685
SOX9 SRY (sex determining region Y)-box 9 -0.00633774
BTG1 B-cell translocation gene 1, anti-proliferative -0.00633496
VNN1 vanin 1 -0.00633463
AQP9 aquaporin 9 -0.00630504
CD79B CD79b molecule, immunoglobulin-associated beta -0.00629417
RRAGA Ras-related GTP binding A -0.00627916
TSPAN1 tetraspanin 1 -0.00625939
MT1H metallothionein 1H -0.00624298
C5AR1 complement component 5a receptor 1 -0.00622699
AKAP9 A kinase (PRKA) anchor protein 9 -0.00622673
TM4SF4 transmembrane 4 L six family member 4 -0.00622072
WNT5B wingless-type MMTV integration site family, member 5B -0.0062166
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -0.00621473
ARL8B ADP-ribosylation factor-like 8B -0.00621421
KRT17 keratin 17, type I -0.00621215
BANK1 B-cell scaffold protein with ankyrin repeats 1 -0.00620669
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 -0.00619793
SIGLEC15 sialic acid binding Ig-like lectin 15 -0.0061924
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.00615954
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain -0.00615187
CLDN3 claudin 3 -0.0061485
TUBA1A tubulin, alpha 1a -0.00614849
PSCA prostate stem cell antigen -0.00612846
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 -0.00611512
FST follistatin -0.00611319
DCN decorin -0.00611114
COL16A1 collagen, type XVI, alpha 1 -0.00610239
PLXNB2 plexin B2 -0.00610088
COL7A1 collagen, type VII, alpha 1 -0.00608498
CCN2 cellular communication network factor 2 -0.00606946
TM7SF2 transmembrane 7 superfamily member 2 -0.00606421
STK38 serine/threonine kinase 38 -0.00604473
COMP cartilage oligomeric matrix protein -0.00598183
TMEM45A transmembrane protein 45A -0.00597048
FBLN1 fibulin 1 -0.00595153
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -0.00594494
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 -0.00593982
SCGB1D2 secretoglobin, family 1D, member 2 -0.00592817
CXCL9 chemokine (C-X-C motif) ligand 9 -0.0059098
FAM171A1 family with sequence similarity 171, member A1 -0.00590877
GCHFR GTP cyclohydrolase I feedback regulator -0.00589901
ALOX5 arachidonate 5-lipoxygenase -0.0058939
MBD2 methyl-CpG binding domain protein 2 -0.0058771
BCL7A B-cell CLL/lymphoma 7A -0.00587195
CUEDC1 CUE domain containing 1 -0.00584234
BTG2 BTG family, member 2 -0.00584206
SH3BGRL SH3 domain binding glutamate-rich protein like -0.00582163
MCUB mitochondrial calcium uniporter dominant negative subunit beta -0.00581723
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.00580333
TUBA4A tubulin, alpha 4a -0.0057801
DCXR dicarbonyl/L-xylulose reductase -0.00577388
RTN3 reticulon 3 -0.0057476
BCR breakpoint cluster region -0.00574695
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.00574531
SLPI secretory leukocyte peptidase inhibitor -0.00574305
IFI6 interferon, alpha-inducible protein 6 -0.00572789
CAPN1 calpain 1, (mu/I) large subunit -0.00571743
SEPTIN11 septin 11 -0.00571096
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.00569961
SIRT3 sirtuin 3 -0.00568191
MUC5AC mucin 5AC, oligomeric mucus/gel-forming -0.00565836
IQSEC1 IQ motif and Sec7 domain 1 -0.00565692
BPI bactericidal/permeability-increasing protein -0.00565303
SIK1 salt-inducible kinase 1 -0.00564976
KRT6B keratin 6B, type II -0.00564676
MT1F metallothionein 1F -0.00564394
EIF5A eukaryotic translation initiation factor 5A -0.00563012
NID2 nidogen 2 (osteonidogen) -0.00562623
CFB complement factor B -0.00561905
MYO6 myosin VI -0.00561481
HBD hemoglobin, delta -0.00559872
RANGAP1 Ran GTPase activating protein 1 -0.00559774
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.00559548
HLA-DMB major histocompatibility complex, class II, DM beta -0.00559512
CLGN calmegin -0.00558068
TSPO translocator protein (18kDa) -0.00557866
F12 coagulation factor XII (Hageman factor) -0.00557697
CCL5 chemokine (C-C motif) ligand 5 -0.00557116
TGM2 transglutaminase 2 -0.00556927
SQSTM1 sequestosome 1 -0.00556355
MAGED1 melanoma antigen family D1 -0.00555654
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 -0.00555592
MAPKBP1 mitogen-activated protein kinase binding protein 1 -0.00555592
HMOX1 heme oxygenase 1 -0.0055343
TSPYL5 TSPY-like 5 -0.00553129
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 -0.00550857
NRGN neurogranin (protein kinase C substrate, RC3) -0.00550313
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 -0.00548837
TGFA transforming growth factor, alpha -0.00547951
THBS2 thrombospondin 2 -0.00547641
PTK2B protein tyrosine kinase 2 beta -0.00547379
NADK NAD kinase -0.00547276
SPTBN2 spectrin, beta, non-erythrocytic 2 -0.00546839
DNAAF1 dynein, axonemal, assembly factor 1 -0.00546617
TWF2 twinfilin actin binding protein 2 -0.005465
CLMN calmin (calponin-like, transmembrane) -0.00546383
PSD3 pleckstrin and Sec7 domain containing 3 -0.00545238
IDO1 indoleamine 2,3-dioxygenase 1 -0.00543325
STXBP2 syntaxin binding protein 2 -0.00543063
MT1HL1 metallothionein 1H-like 1 -0.00542024
VCAN versican -0.00541825
EYA1 EYA transcriptional coactivator and phosphatase 1 -0.0054172
SRPK2 SRSF protein kinase 2 -0.00540639
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.0053948
NVL nuclear VCP-like -0.0053889
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) -0.0053853
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3 -0.00536665
TPD52L1 tumor protein D52-like 1 -0.00536053
LYPD3 LY6/PLAUR domain containing 3 -0.00535317
DEFA4 defensin, alpha 4, corticostatin -0.00534757
FGB fibrinogen beta chain -0.00534287
CLDN4 claudin 4 -0.00533918
HIST1H2BK histone cluster 1, H2bk -0.00533361
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3 -0.00532854
PRAME preferentially expressed antigen in melanoma -0.00531843
PDGFC platelet derived growth factor C -0.00531403
CD82 CD82 molecule -0.00530339
FBP1 fructose-1,6-bisphosphatase 1 -0.00529557
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) -0.00528649