| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | NLR family, pyrin domain containing 1|This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 22861) |
| External Link | https://ncbi.nlm.nih.gov/gene/22861 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the NLRP1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IFI27 | interferon, alpha-inducible protein 27 | 0.0235549 |
| XIC | X chromosome inactivation center | 0.0205423 |
| S100A10 | S100 calcium binding protein A10 | 0.0159464 |
| GNAS | GNAS complex locus | 0.0129598 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | 0.0128265 |
| LYPD1 | LY6/PLAUR domain containing 1 | 0.0125076 |
| MCL1 | myeloid cell leukemia 1 | 0.0124342 |
| PDZD2 | PDZ domain containing 2 | 0.0123205 |
| KLK5 | kallikrein-related peptidase 5 | 0.0122259 |
| TAC1 | tachykinin, precursor 1 | 0.0121814 |
| GPM6B | glycoprotein M6B | 0.0120879 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0120255 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.0120028 |
| ITGA6 | integrin, alpha 6 | 0.0119185 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0117417 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0116046 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0114547 |
| KRT14 | keratin 14, type I | 0.0114064 |
| XPO7 | exportin 7 | 0.0113971 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0112695 |
| ANXA3 | annexin A3 | 0.0111509 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | 0.0109034 |
| KLK10 | kallikrein-related peptidase 10 | 0.0108592 |
| SYNGR3 | synaptogyrin 3 | 0.0108011 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0105938 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0104455 |
| IFI44L | interferon-induced protein 44-like | 0.01044 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0103731 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 0.010239 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.0101795 |
| SST | somatostatin | 0.0101376 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.0096807 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00962847 |
| EXOC5 | exocyst complex component 5 | 0.00959972 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | 0.00957396 |
| PRNP | prion protein | 0.00955594 |
| MX1 | MX dynamin-like GTPase 1 | 0.00948096 |
| CCND2 | cyclin D2 | 0.00940468 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.00939609 |
| TAGLN2 | transgelin 2 | 0.00929207 |
| PDLIM1 | PDZ and LIM domain 1 | 0.00916371 |
| FABP1 | fatty acid binding protein 1, liver | 0.00915528 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.00915087 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | 0.00903842 |
| MBD1 | methyl-CpG binding domain protein 1 | 0.00901739 |
| FABP7 | fatty acid binding protein 7, brain | 0.00899135 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0089318 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00893125 |
| ASS1 | argininosuccinate synthase 1 | 0.00890115 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00887246 |
| BEX1 | brain expressed, X-linked 1 | 0.00886668 |
| DEFB1 | defensin, beta 1 | 0.00884648 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | 0.00876992 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.00869148 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.00868724 |
| MAGEA12 | melanoma antigen family A12 | 0.00860019 |
| PLLP | plasmolipin | 0.00858485 |
| TSPAN13 | tetraspanin 13 | 0.00854367 |
| OXTR | oxytocin receptor | 0.00851441 |
| PLK2 | polo-like kinase 2 | 0.00849325 |
| KRT5 | keratin 5, type II | 0.00846554 |
| S100A11 | S100 calcium binding protein A11 | 0.00840459 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00839366 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | 0.0083924 |
| MYO1C | myosin IC | 0.0083829 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | 0.00836101 |
| SOX17 | SRY (sex determining region Y)-box 17 | 0.00835584 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.00835462 |
| GAB2 | GRB2-associated binding protein 2 | 0.00832083 |
| TRIM22 | tripartite motif containing 22 | 0.00827284 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.00826239 |
| LAMC2 | laminin, gamma 2 | 0.00817888 |
| SNX7 | sorting nexin 7 | 0.00816803 |
| EDNRB | endothelin receptor type B | 0.00811156 |
| CA2 | carbonic anhydrase II | 0.0080996 |
| NRBF2 | nuclear receptor binding factor 2 | 0.00808272 |
| ANXA1 | annexin A1 | 0.00807789 |
| APOB | apolipoprotein B | 0.00805235 |
| CCL14 | chemokine (C-C motif) ligand 14 | 0.00801561 |
| HAL | histidine ammonia-lyase | 0.00799794 |
| MAGEA3 | melanoma antigen family A3 | 0.00795359 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00787033 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.00785213 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | 0.00782453 |
| TPBG | trophoblast glycoprotein | 0.00780558 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.00777329 |
| GTF3C3 | general transcription factor IIIC, polypeptide 3, 102kDa | 0.00776918 |
| STK10 | serine/threonine kinase 10 | 0.00774002 |
| HMBOX1 | homeobox containing 1 | 0.00771761 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00769213 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.00768907 |
| MATN2 | matrilin 2 | 0.0076726 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.00766194 |
| TANK | TRAF family member-associated NFKB activator | 0.00766095 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 0.00765972 |
| RNFT1 | ring finger protein, transmembrane 1 | 0.00765215 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.00762935 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0075973 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00757207 |
| REEP5 | receptor accessory protein 5 | 0.0075468 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | 0.00752354 |
| TEX10 | testis expressed 10 | 0.00751122 |
| LPIN1 | lipin 1 | 0.00750636 |
| PTHLH | parathyroid hormone-like hormone | 0.00749804 |
| CLDND1 | claudin domain containing 1 | 0.00749744 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | 0.00747616 |
| CTTN | cortactin | 0.00747045 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0074651 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | 0.00741447 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.00737307 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.00736797 |
| HSPA4L | heat shock 70kDa protein 4-like | 0.0073641 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.00736183 |
| SLC35G2 | solute carrier family 35, member G2 | 0.00736025 |
| CADM1 | cell adhesion molecule 1 | 0.00733871 |
| STK17A | serine/threonine kinase 17a | 0.00731782 |
| QPRT | quinolinate phosphoribosyltransferase | 0.00728214 |
| ERGIC2 | ERGIC and golgi 2 | 0.00727969 |
| PODXL | podocalyxin-like | 0.00727868 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.00727644 |
| MAGEA1 | melanoma antigen family A1 | 0.00727509 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 0.00725975 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | 0.0072539 |
| LEPROT | leptin receptor overlapping transcript | 0.00724612 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.00723118 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00718763 |
| CFI | complement factor I | 0.00716086 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.00715668 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.00712756 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.00706942 |
| RANBP9 | RAN binding protein 9 | 0.00706356 |
| S100P | S100 calcium binding protein P | 0.00705872 |
| CD59 | CD59 molecule, complement regulatory protein | 0.00703588 |
| NID1 | nidogen 1 | 0.00699707 |
| FGF13 | fibroblast growth factor 13 | 0.00699574 |
| IL1A | interleukin 1, alpha | 0.00698043 |
| FNBP1 | formin binding protein 1 | 0.00697821 |
| DCHS1 | dachsous cadherin-related 1 | 0.00694335 |
| DSG1 | desmoglein 1 | 0.00694175 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.00692904 |
| RBM34 | RNA binding motif protein 34 | 0.0069266 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.00690123 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit | 0.00686934 |
| LAMA3 | laminin, alpha 3 | 0.00686521 |
| EDN3 | endothelin 3 | 0.00686004 |
| EMP1 | epithelial membrane protein 1 | 0.00682041 |
| ALB | albumin | 0.006819 |
| BCHE | butyrylcholinesterase | 0.00681682 |
| CLIC5 | chloride intracellular channel 5 | 0.00680463 |
| CAV2 | caveolin 2 | 0.00680462 |
| CARD10 | caspase recruitment domain family, member 10 | 0.00677874 |
| COL4A2 | collagen, type IV, alpha 2 | 0.00677541 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | 0.00677166 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00676609 |
| JMJD1C | jumonji domain containing 1C | 0.00675994 |
| ANKRD11 | ankyrin repeat domain 11 | 0.00675464 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.00674879 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.0067163 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.00671246 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.00670359 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.00670295 |
| MFAP3L | microfibrillar-associated protein 3-like | 0.00670182 |
| KLF6 | Kruppel-like factor 6 | 0.00668899 |
| ARG1 | arginase 1 | 0.00668172 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.0066782 |
| MICB | MHC class I polypeptide-related sequence B | 0.00667443 |
| FAM169A | family with sequence similarity 169, member A | 0.00666963 |
| ARL5A | ADP-ribosylation factor-like 5A | 0.00665221 |
| APOA2 | apolipoprotein A-II | 0.00665115 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | 0.00664397 |
| NEK7 | NIMA-related kinase 7 | 0.0066227 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.00662085 |
| RNASET2 | ribonuclease T2 | 0.00658691 |
| HP | haptoglobin | 0.00658602 |
| ZFYVE21 | zinc finger, FYVE domain containing 21 | 0.00658511 |
| RIDA | reactive intermediate imine deaminase A homolog | 0.00655233 |
| ORM1 | orosomucoid 1 | 0.00654883 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | 0.00654445 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.00653854 |
| IFI44 | interferon-induced protein 44 | 0.00653723 |
| MT1X | metallothionein 1X | 0.0065367 |
| C9 | complement component 9 | 0.00652825 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.00652053 |
| CALML5 | calmodulin-like 5 | 0.00651917 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.00648691 |
| MAP3K7CL | MAP3K7 C-terminal like | 0.00648634 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.00647191 |
| PUF60 | poly-U binding splicing factor 60KDa | 0.0064604 |
| PXDN | peroxidasin | 0.00645589 |
| TKTL1 | transketolase-like 1 | 0.00644171 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.00644148 |
| BTG3 | BTG family, member 3 | 0.00642004 |
| FOXG1 | forkhead box G1 | 0.00640389 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.00639853 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00638545 |
| RNF11 | ring finger protein 11 | 0.00637841 |
| RNF103 | ring finger protein 103 | 0.00637499 |
| ARMT1 | acidic residue methyltransferase 1 | 0.006365 |
| TRAM1 | translocation associated membrane protein 1 | 0.00635987 |
| DMD | dystrophin | 0.00635663 |
| FZD3 | frizzled class receptor 3 | 0.00635032 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | 0.0063354 |
| TFDP1 | transcription factor Dp-1 | 0.0063128 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | 0.00631019 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0063061 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.00629869 |
| MYO1B | myosin IB | 0.00629801 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.00629503 |
| CLEC2D | C-type lectin domain family 2, member D | 0.00626099 |
| PTCH1 | patched 1 | 0.00624293 |
| CBFB | core-binding factor, beta subunit | 0.00623867 |
| C4ORF19 | chromosome 4 open reading frame 19 | 0.00623824 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.00623611 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.00622705 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | 0.0062229 |
| IL1R2 | interleukin 1 receptor, type II | 0.00621973 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00621558 |
| FZD6 | frizzled class receptor 6 | 0.00621311 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.00620933 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.00620908 |
| CCL4 | chemokine (C-C motif) ligand 4 | 0.00619928 |
| ZNF281 | zinc finger protein 281 | 0.00619373 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.00618409 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.00617136 |
| KRT23 | keratin 23, type I | 0.00616775 |
| PIGP | phosphatidylinositol glycan anchor biosynthesis, class P | 0.00616484 |
| COPA | coatomer protein complex, subunit alpha | 0.00615706 |
| AADAC | arylacetamide deacetylase | 0.00614532 |
| FHL2 | four and a half LIM domains 2 | 0.00613138 |
| ELOVL2 | ELOVL fatty acid elongase 2 | 0.00612784 |
| RBM25 | RNA binding motif protein 25 | 0.00612266 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00611948 |
| DAZAP2 | DAZ associated protein 2 | 0.00611352 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.0061031 |
| SLC16A2 | solute carrier family 16, member 2 (thyroid hormone transporter) | 0.00609583 |
| NKG7 | natural killer cell granule protein 7 | 0.00608647 |
| HIST1H2AC | histone cluster 1, H2ac | 0.00608008 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.00606734 |
| USP34 | ubiquitin specific peptidase 34 | 0.00606706 |
| CAPRIN2 | caprin family member 2 | 0.00605625 |
| IL6ST | interleukin 6 signal transducer | 0.00603764 |
| RNF44 | ring finger protein 44 | 0.00602197 |
| PLS3 | plastin 3 | 0.00599394 |
| ITM2C | integral membrane protein 2C | 0.00599157 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.00598192 |
| TYRP1 | tyrosinase-related protein 1 | 0.0059411 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.0059409 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00593028 |
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.00592552 |
| Symbol | Name | Standardized Value |
|---|---|---|
| WDR7 | WD repeat domain 7 | -0.0285966 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0250876 |
| MAP7 | microtubule-associated protein 7 | -0.0213466 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0196565 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.0138448 |
| TOX3 | TOX high mobility group box family member 3 | -0.0138065 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0133442 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.0132824 |
| TPSAB1 | tryptase alpha/beta 1 | -0.0126412 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -0.0126389 |
| PLPP3 | phospholipid phosphatase 3 | -0.0125529 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0122185 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.0121704 |
| TMSB15A | thymosin beta 15a | -0.0119115 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.0118154 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0115732 |
| CD52 | CD52 molecule | -0.011558 |
| MAOA | monoamine oxidase A | -0.0114566 |
| LTF | lactotransferrin | -0.0113837 |
| TSPAN4 | tetraspanin 4 | -0.0113774 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0111046 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.0110392 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0109613 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0108885 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.0108529 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.0106742 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.0105908 |
| FADS1 | fatty acid desaturase 1 | -0.0103515 |
| FASN | fatty acid synthase | -0.0100659 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0100326 |
| RAPSN | receptor-associated protein of the synapse | -0.00982002 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | -0.00981553 |
| AEBP1 | AE binding protein 1 | -0.00972761 |
| ICA1 | islet cell autoantigen 1, 69kDa | -0.00960148 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.0095524 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00954396 |
| SLC44A4 | solute carrier family 44, member 4 | -0.00951413 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00945975 |
| FST | follistatin | -0.00943617 |
| RTN1 | reticulon 1 | -0.00940577 |
| NID2 | nidogen 2 (osteonidogen) | -0.00938813 |
| H1-2 | H1.2 linker histone, cluster member | -0.00935072 |
| JPT2 | Jupiter microtubule associated homolog 2 | -0.00928435 |
| TMC5 | transmembrane channel-like 5 | -0.00927835 |
| CTBP2 | C-terminal binding protein 2 | -0.00925882 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.00919521 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | -0.00906598 |
| GUSB | glucuronidase, beta | -0.00903474 |
| RTN3 | reticulon 3 | -0.00901701 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00901134 |
| AGR2 | anterior gradient 2 | -0.00896789 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.00889048 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00889043 |
| COLEC12 | collectin sub-family member 12 | -0.00888827 |
| IL1R1 | interleukin 1 receptor, type I | -0.00886514 |
| FBLN1 | fibulin 1 | -0.00884915 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 | -0.00884212 |
| MMP12 | matrix metallopeptidase 12 | -0.00882178 |
| KIAA0930 | KIAA0930 | -0.00880367 |
| LXN | latexin | -0.00872716 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00866525 |
| ASB13 | ankyrin repeat and SOCS box containing 13 | -0.00865925 |
| NVL | nuclear VCP-like | -0.0086567 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.00865425 |
| TRIB2 | tribbles pseudokinase 2 | -0.00861853 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.0085735 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.00856129 |
| TGM2 | transglutaminase 2 | -0.00853329 |
| CLDN4 | claudin 4 | -0.00852594 |
| DCXR | dicarbonyl/L-xylulose reductase | -0.00851782 |
| HOXC6 | homeobox C6 | -0.00849467 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.00844122 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00841059 |
| BMP4 | bone morphogenetic protein 4 | -0.00835939 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | -0.00835808 |
| TNC | tenascin C | -0.00829064 |
| NNMT | nicotinamide N-methyltransferase | -0.00828907 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.00825381 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | -0.00822496 |
| COG7 | component of oligomeric golgi complex 7 | -0.00821154 |
| PNPLA6 | patatin-like phospholipase domain containing 6 | -0.00811576 |
| CRYM | crystallin, mu | -0.00811171 |
| ZNF331 | zinc finger protein 331 | -0.00810271 |
| CRLF1 | cytokine receptor-like factor 1 | -0.00807845 |
| IPO13 | importin 13 | -0.00806881 |
| KLK3 | kallikrein-related peptidase 3 | -0.00802082 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.00798099 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.00794068 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | -0.0078976 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | -0.00789166 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00785669 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | -0.00784299 |
| SOCS1 | suppressor of cytokine signaling 1 | -0.00783904 |
| CLGN | calmegin | -0.00778558 |
| EPHB6 | EPH receptor B6 | -0.00774399 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.00774018 |
| PMP22 | peripheral myelin protein 22 | -0.0077346 |
| TCF4 | transcription factor 4 | -0.00772273 |
| SEPTIN11 | septin 11 | -0.00769359 |
| IL7R | interleukin 7 receptor | -0.00766945 |
| MXRA8 | matrix-remodelling associated 8 | -0.0076627 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.00760497 |
| ADCY2 | adenylate cyclase 2 (brain) | -0.00760147 |
| CLDN3 | claudin 3 | -0.00755914 |
| TMPRSS2 | transmembrane protease, serine 2 | -0.00753417 |
| MLPH | melanophilin | -0.00749703 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | -0.00749564 |
| C10ORF10 | chromosome 10 open reading frame 10 | -0.00748196 |
| MACROD1 | MACRO domain containing 1 | -0.00748004 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | -0.00747634 |
| LOX | lysyl oxidase | -0.00742398 |
| TBC1D4 | TBC1 domain family, member 4 | -0.00742165 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.00740331 |
| KLK2 | kallikrein-related peptidase 2 | -0.00739746 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.00737953 |
| TSPO | translocator protein (18kDa) | -0.00737662 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00735378 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.00735266 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | -0.00729932 |
| IGSF6 | immunoglobulin superfamily, member 6 | -0.00727148 |
| TM7SF2 | transmembrane 7 superfamily member 2 | -0.00725247 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma | -0.00721165 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -0.00720664 |
| CHEK2 | checkpoint kinase 2 | -0.00719421 |
| EFHD2 | EF-hand domain family, member D2 | -0.00716748 |
| C1ORF115 | chromosome 1 open reading frame 115 | -0.00716119 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | -0.0071415 |
| PYGB | phosphorylase, glycogen; brain | -0.00711846 |
| CD1C | CD1c molecule | -0.00709623 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.00707204 |
| NPR3 | natriuretic peptide receptor 3 | -0.00707114 |
| GOLM1 | golgi membrane protein 1 | -0.00704879 |
| FAM13A | family with sequence similarity 13, member A | -0.00704793 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.00702081 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.00700566 |
| NKX3-1 | NK3 homeobox 1 | -0.00697048 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | -0.00693732 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | -0.00691174 |
| RRAGA | Ras-related GTP binding A | -0.00690512 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | -0.00690029 |
| CLEC10A | C-type lectin domain family 10, member A | -0.00685793 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00685067 |
| AP2S1 | adaptor-related protein complex 2, sigma 1 subunit | -0.00685031 |
| CYB5A | cytochrome b5 type A (microsomal) | -0.00684499 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00683332 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 | -0.0068321 |
| BCL7B | B-cell CLL/lymphoma 7B | -0.00683037 |
| PDLIM3 | PDZ and LIM domain 3 | -0.00682458 |
| TXNL1 | thioredoxin-like 1 | -0.00681943 |
| SSBP3 | single stranded DNA binding protein 3 | -0.00681862 |
| ST18 | suppression of tumorigenicity 18, zinc finger | -0.00680521 |
| CNTNAP2 | contactin associated protein-like 2 | -0.00675942 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.00675671 |
| INSM1 | insulinoma-associated 1 | -0.00675345 |
| ZCCHC2 | zinc finger, CCHC domain containing 2 | -0.00674525 |
| DGKZ | diacylglycerol kinase, zeta | -0.00673698 |
| H2AX | H2A.X variant histone | -0.00672856 |
| GAS1 | growth arrest-specific 1 | -0.00671467 |
| CBX5 | chromobox homolog 5 | -0.00670943 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) | -0.00670903 |
| SCPEP1 | serine carboxypeptidase 1 | -0.00670081 |
| CHKB | choline kinase beta | -0.00667553 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 | -0.00666894 |
| HK2 | hexokinase 2 | -0.0066356 |
| ISYNA1 | inositol-3-phosphate synthase 1 | -0.00662455 |
| TGFB1 | transforming growth factor, beta 1 | -0.00661067 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.00660577 |
| PLXNB2 | plexin B2 | -0.0066017 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00658889 |
| MRTFB | myocardin related transcription factor B | -0.00658869 |
| BCL7A | B-cell CLL/lymphoma 7A | -0.00658311 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 | -0.00658153 |
| DHCR24 | 24-dehydrocholesterol reductase | -0.00654541 |
| RNF144A | ring finger protein 144A | -0.00653891 |
| SFTPA2 | surfactant protein A2 | -0.00653632 |
| LPAR1 | lysophosphatidic acid receptor 1 | -0.00653263 |
| G6PD | glucose-6-phosphate dehydrogenase | -0.006527 |
| COMP | cartilage oligomeric matrix protein | -0.0065246 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.00652139 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | -0.00651525 |
| DPP4 | dipeptidyl-peptidase 4 | -0.00649013 |
| PRKCSH | protein kinase C substrate 80K-H | -0.00645787 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -0.00645647 |
| MMP9 | matrix metallopeptidase 9 | -0.00645449 |
| RANGAP1 | Ran GTPase activating protein 1 | -0.0064287 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0064281 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.00641691 |
| RCAN2 | regulator of calcineurin 2 | -0.0064039 |
| HPGDS | hematopoietic prostaglandin D synthase | -0.00638911 |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 | -0.00637199 |
| DCLK1 | doublecortin-like kinase 1 | -0.00636249 |
| CD84 | CD84 molecule | -0.00635905 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | -0.00634695 |
| LRRC15 | leucine rich repeat containing 15 | -0.00633894 |
| CENPM | centromere protein M | -0.00633346 |
| ZWINT | ZW10 interacting kinetochore protein | -0.00631163 |
| FBP1 | fructose-1,6-bisphosphatase 1 | -0.00629689 |
| CAMP | cathelicidin antimicrobial peptide | -0.00629043 |
| NSMCE4A | non-SMC element 4 homolog A (S. cerevisiae) | -0.00628584 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.00627361 |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) | -0.00627175 |
| PKM | pyruvate kinase, muscle | -0.00623373 |
| GPX4 | glutathione peroxidase 4 | -0.00620027 |
| KRT17 | keratin 17, type I | -0.00619071 |
| HNMT | histamine N-methyltransferase | -0.00618414 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 | -0.00617271 |
| MAZ | MYC-associated zinc finger protein (purine-binding transcription factor) | -0.00614374 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.00612521 |
| HMGB2 | high mobility group box 2 | -0.00612334 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00612045 |
| MTARC1 | mitochondrial amidoxime reducing component 1 | -0.0061169 |
| THOC6 | THO complex 6 | -0.00610452 |
| SUN2 | Sad1 and UNC84 domain containing 2 | -0.00608837 |
| PHGDH | phosphoglycerate dehydrogenase | -0.00608719 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00608645 |
| F5 | coagulation factor V (proaccelerin, labile factor) | -0.0060844 |
| NARF | nuclear prelamin A recognition factor | -0.00607992 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 | -0.00607821 |
| INTS1 | integrator complex subunit 1 | -0.00606606 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | -0.00605151 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | -0.00604822 |
| BIRC5 | baculoviral IAP repeat containing 5 | -0.00604801 |
| EHD2 | EH-domain containing 2 | -0.00604286 |
| CLDN8 | claudin 8 | -0.00598272 |
| STK39 | serine threonine kinase 39 | -0.0059799 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.00597543 |
| TSPAN1 | tetraspanin 1 | -0.00597487 |
| GCHFR | GTP cyclohydrolase I feedback regulator | -0.00596079 |
| CLIC2 | chloride intracellular channel 2 | -0.00592921 |
| ACP3 | acid phosphatase 3 | -0.00592706 |
| CST6 | cystatin E/M | -0.00592624 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0059017 |
| ECHS1 | enoyl CoA hydratase, short chain, 1, mitochondrial | -0.00590115 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.00587989 |
| ADM | adrenomedullin | -0.00587577 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.00587551 |
| SNRNP40 | small nuclear ribonucleoprotein 40kDa (U5) | -0.00585374 |
| MED22 | mediator complex subunit 22 | -0.00584035 |
| TBC1D16 | TBC1 domain family, member 16 | -0.00582709 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.00582536 |
| LAMB2 | laminin, beta 2 (laminin S) | -0.00581192 |
| PIR | pirin (iron-binding nuclear protein) | -0.00579773 |
| JAG1 | jagged 1 | -0.00579708 |
| PFKP | phosphofructokinase, platelet | -0.00578699 |
| FIG4 | FIG4 phosphoinositide 5-phosphatase | -0.00578582 |
| AK1 | adenylate kinase 1 | -0.00577069 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.00576877 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00576764 |
| ATXN10 | ataxin 10 | -0.00576649 |
