NME1 Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description NME/NM23 nucleoside diphosphate kinase 1|This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4830)
External Link http://www.ncbi.nlm.nih.gov/gene/4830
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Genes

2 substrates of the kinase NME1 from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
KSR1 kinase suppressor of ras 1
NME1 NME/NM23 nucleoside diphosphate kinase 1