NMI Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description N-myc (and STAT) interactor|NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 9111)
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Genes

278 genes differentially expressed following the NMI gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
MAGEC3 melanoma antigen family C3 2.90426
GPR21 G protein-coupled receptor 21 2.90426
BATF basic leucine zipper transcription factor, ATF-like 2.90426
CEP295NL CEP295 N-terminal like 2.90426
DMRTC1B DMRT-like family C1B 2.90426
CD300A CD300a molecule 2.90426
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 2.90426
HBA1 hemoglobin, alpha 1 2.90426
GJB3 gap junction protein, beta 3, 31kDa 2.90426
WT1 Wilms tumor 1 2.90426
SLC25A41 solute carrier family 25, member 41 2.90426
MILR1 mast cell immunoglobulin-like receptor 1 2.90426
TMEM244 transmembrane protein 244 2.90426
SLC35G6 solute carrier family 35, member G6 2.90426
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 2.90426
FUCA1 fucosidase, alpha-L- 1, tissue 2.90426
FBXL8 F-box and leucine-rich repeat protein 8 2.90426
SCGN secretagogin, EF-hand calcium binding protein 2.90426
SPINT3 serine peptidase inhibitor, Kunitz type, 3 2.90426
ANKRD34C ankyrin repeat domain 34C 2.90426
CD3E CD3e molecule, epsilon (CD3-TCR complex) 2.90426
BTBD16 BTB (POZ) domain containing 16 2.90426
DEFB105A defensin, beta 105A 2.90426
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial 2.90426
HIC1 hypermethylated in cancer 1 2.90426
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 2.90426
TPPP tubulin polymerization promoting protein 2.90426
CSNK2A3 casein kinase 2, alpha 3 polypeptide 2.90426
RPEL1 ribulose-5-phosphate-3-epimerase-like 1 2.90426
SP6 Sp6 transcription factor 2.90426
CPLX3 complexin 3 2.90426
ATOH7 atonal homolog 7 (Drosophila) 2.90426
HBM hemoglobin, mu 2.90426
OR5V1 olfactory receptor, family 5, subfamily V, member 1 2.90426
PNOC prepronociceptin 2.90426
DEFB124 defensin, beta 124 2.90426
BIRC3 baculoviral IAP repeat containing 3 2.90426
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 2.90426
CARD16 caspase recruitment domain family, member 16 2.90426
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma 2.90426
FGFBP2 fibroblast growth factor binding protein 2 2.90426
TAS1R1 taste receptor, type 1, member 1 2.90426
ZAR1L zygote arrest 1-like 2.90426
GPR85 G protein-coupled receptor 85 2.90426
ROPN1 rhophilin associated tail protein 1 2.90426
OR52E5 olfactory receptor, family 52, subfamily E, member 5 2.90426
PLCZ1 phospholipase C, zeta 1 2.90426
KRT80 keratin 80, type II 2.90426
ELOVL3 ELOVL fatty acid elongase 3 2.90426
RIPK4 receptor-interacting serine-threonine kinase 4 2.90426
MT4 metallothionein 4 2.90426
CALHM5 calcium homeostasis modulator family member 5 2.90426
CIROP ciliated left-right organizer metallopeptidase 2.90426
CFAP91 cilia and flagella associated protein 91 2.90426
PPDPFL pancreatic progenitor cell differentiation and proliferation factor like 2.90426
IHO1 interactor of HORMAD1 1 2.90426
MYMK myomaker, myoblast fusion factor 2.90426
PTH parathyroid hormone 2.90426
BLNK B-cell linker 2.90426
SELPLG selectin P ligand 2.90426
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18 2.90426
TMEM212 transmembrane protein 212 2.90426
CFHR4 complement factor H-related 4 2.90426
SLCO1B3 solute carrier organic anion transporter family, member 1B3 2.90426
PLVAP plasmalemma vesicle associated protein 2.90426
OR5H1 olfactory receptor, family 5, subfamily H, member 1 2.90426
PCDHA2 protocadherin alpha 2 2.90426
PRB2 proline-rich protein BstNI subfamily 2 2.90426
PTPRH protein tyrosine phosphatase, receptor type, H 2.90426
CLDN9 claudin 9 2.90426
DSG1 desmoglein 1 2.90426
IL5 interleukin 5 2.90426
C1QTNF9 C1q and tumor necrosis factor related protein 9 2.90426
PRR18 proline rich 18 2.90426
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 2.90426
RGS21 regulator of G-protein signaling 21 2.90426
RPSA2 ribosomal protein SA 2 2.90426
IGLL1 immunoglobulin lambda-like polypeptide 1 2.90426
SLC6A17 solute carrier family 6 (neutral amino acid transporter), member 17 2.90426
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 2.90426
LHFPL2 lipoma HMGIC fusion partner-like 2 2.90426
CRYBB3 crystallin, beta B3 2.90426
VNN2 vanin 2 2.90426
GJB6 gap junction protein, beta 6, 30kDa 2.90426
ARR3 arrestin 3, retinal (X-arrestin) 2.90426
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1 2.90426
ADORA3 adenosine A3 receptor 2.90426
CLDN34 claudin 34 2.90426
C10ORF105 chromosome 10 open reading frame 105 2.90426
FBXO39 F-box protein 39 2.90426
CGB7 chorionic gonadotropin, beta polypeptide 7 2.90426
TLR10 toll-like receptor 10 2.90426
TTC9B tetratricopeptide repeat domain 9B 2.90426
PNLIP pancreatic lipase 2.90426
SIGLEC11 sialic acid binding Ig-like lectin 11 2.90426
TBX1 T-box 1 2.90426
KLK7 kallikrein-related peptidase 7 2.90426
FBXO40 F-box protein 40 2.90426
LRTM3 leucine rich repeat transmembrane protein 3 2.90426
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 2.90426
TEKT2 tektin 2 (testicular) 2.90426
MEIS2 Meis homeobox 2 2.90426
OR52K1 olfactory receptor, family 52, subfamily K, member 1 2.90426
IFNL4 interferon, lambda 4 (gene/pseudogene) 2.90426
PREB prolactin regulatory element binding 2.90426
TBPL2 TATA box binding protein like 2 2.90426
PLEKHS1 pleckstrin homology domain containing, family S member 1 2.90426
TCF21 transcription factor 21 2.90426
NUTM2D NUT family member 2D 2.90426
NUTM2B NUT family member 2B 2.90426
PSORS1C1 psoriasis susceptibility 1 candidate 1 2.90426
PRAP1 proline-rich acidic protein 1 2.90426
ADGRF5 adhesion G protein-coupled receptor F5 2.90426
SLITRK1 SLIT and NTRK-like family, member 1 2.90426
HHIPL2 HHIP-like 2 2.90426
APOL3 apolipoprotein L, 3 2.90426
DUOXA1 dual oxidase maturation factor 1 2.90426
LRRC38 leucine rich repeat containing 38 2.90426
CLCNKA chloride channel, voltage-sensitive Ka 2.90426
GPR179 G protein-coupled receptor 179 2.90426
TGM1 transglutaminase 1 2.90426
IL17B interleukin 17B 2.90426
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 2.90426
CCDC70 coiled-coil domain containing 70 2.90426
AGR3 anterior gradient 3 2.90426
SYCE1 synaptonemal complex central element protein 1 2.90426
CFH complement factor H 2.90426
LY6G6C lymphocyte antigen 6 complex, locus G6C 2.90426
OR1B1 olfactory receptor, family 1, subfamily B, member 1 (gene/pseudogene) 2.90426
TEX53 testis expressed 53 2.86589
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18 2.86296
PCDHGB1 protocadherin gamma subfamily B, 1 2.86296
PABPC1L2A poly(A) binding protein, cytoplasmic 1-like 2A 2.86296
CTAGE9 CTAGE family, member 9 2.83898
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 2.66302
CNTNAP1 contactin associated protein 1 2.60158
SRCAP Snf2-related CREBBP activator protein 2.57528
MCUR1 mitochondrial calcium uniporter regulator 1 2.55195
PRDM5 PR domain containing 5 2.51171
MYBBP1A MYB binding protein (P160) 1a 2.50635
STAT4 signal transducer and activator of transcription 4 2.42533
SSC5D scavenger receptor cysteine rich family, 5 domains 2.40999
SOAT1 sterol O-acyltransferase 1 2.40868
TRIM24 tripartite motif containing 24 2.399
PEX19 peroxisomal biogenesis factor 19 2.39134
ADCY9 adenylate cyclase 9 2.38074
GGT5 gamma-glutamyltransferase 5 2.32493
SPMIP11 sperm microtubule inner protein 11 2.32493
CATSPERT catsper channel auxiliary subunit tau 2.28785
LMOD2 leiomodin 2 (cardiac) 2.28519
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) 2.2835
DCHS1 dachsous cadherin-related 1 2.2835
CRNKL1 crooked neck pre-mRNA splicing factor 1 2.2835
TRIM61 tripartite motif containing 61 2.28163
FNBP1L formin binding protein 1-like 2.2708
MEPE matrix extracellular phosphoglycoprotein 2.26659
NUP210 nucleoporin 210kDa 2.26659
EBF2 early B-cell factor 2 2.26659
EFHC2 EF-hand domain (C-terminal) containing 2 2.26523
SLC16A13 solute carrier family 16, member 13 2.24907
YPEL2 yippee-like 2 (Drosophila) 2.24446
NANS N-acetylneuraminic acid synthase 2.20596
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 2.16637
PSIP1 PC4 and SFRS1 interacting protein 1 2.16132
MTREX Mtr4 exosome RNA helicase 2.15945
PCDHB3 protocadherin beta 3 2.15675
CENPW centromere protein W 2.12724
NAA80 N-alpha-acetyltransferase 80, NatH catalytic subunit 2.11983
C4ORF36 chromosome 4 open reading frame 36 2.11983
NCAPD2 non-SMC condensin I complex, subunit D2 2.10905
PYROXD2 pyridine nucleotide-disulphide oxidoreductase domain 2 2.10655
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 2.1048
DUSP28 dual specificity phosphatase 28 2.1048
VRTN vertebrae development associated 2.09348
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 2.07214
PKD1 polycystic kidney disease 1 (autosomal dominant) 2.07214
CACNG6 calcium channel, voltage-dependent, gamma subunit 6 2.05382
DOK3 docking protein 3 2.05122
UBE2QL1 ubiquitin-conjugating enzyme E2Q family-like 1 2.0501
STRC stereocilin 2.0501
UNC93A unc-93 homolog A (C. elegans) 2.0501
FXYD1 FXYD domain containing ion transport regulator 1 2.04169
PPARD peroxisome proliferator-activated receptor delta 2.0407
ZNF14 zinc finger protein 14 2.0407
GPR75-ASB3 GPR75-ASB3 readthrough 2.0407
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 2.03249
ZNF22 zinc finger protein 22 2.02857
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 2.01568
IFTAP intraflagellar transport associated protein 2.01568
RPL22L1 ribosomal protein L22-like 1 2.01568
SLC24A5 solute carrier family 24 (sodium/potassium/calcium exchanger), member 5 2.00569

decreased expression

Symbol Name Standardized Value
OR52N2 olfactory receptor, family 52, subfamily N, member 2 -2.90426
SCT secretin -2.90426
MPZL2 myelin protein zero-like 2 -2.90426
STX5 syntaxin 5 -2.90426
IGF1 insulin-like growth factor 1 (somatomedin C) -2.90426
LAT linker for activation of T cells -2.90426
AOX1 aldehyde oxidase 1 -2.90426
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1 -2.90426
ZNF35 zinc finger protein 35 -2.86589
SIM2 single-minded family bHLH transcription factor 2 -2.80219
FAM216B family with sequence similarity 216, member B -2.80219
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 -2.80219
LKAAEAR1 LKAAEAR motif containing 1 -2.80219
GDF7 growth differentiation factor 7 -2.80219
TLR2 toll-like receptor 2 -2.80219
SNTN sentan, cilia apical structure protein -2.80219
CMTM2 CKLF-like MARVEL transmembrane domain containing 2 -2.80219
ZFAND1 zinc finger, AN1-type domain 1 -2.80219
PXT1 peroxisomal, testis specific 1 -2.80219
EPX eosinophil peroxidase -2.80219
F5 coagulation factor V (proaccelerin, labile factor) -2.80219
EDN1 endothelin 1 -2.80219
BTNL2 butyrophilin-like 2 -2.80219
BTNL8 butyrophilin-like 8 -2.80219
TTLL13 tubulin tyrosine ligase like 13 -2.80219
DRC1 dynein regulatory complex subunit 1 -2.80219
FKBP1C FK506 binding protein 1C -2.80219
P2RY8 purinergic receptor P2Y, G-protein coupled, 8 -2.80219
ELAVL4 ELAV like neuron-specific RNA binding protein 4 -2.80219
FAM124A family with sequence similarity 124A -2.80219
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -2.80219
TTLL8 tubulin tyrosine ligase-like family member 8 -2.80219
TMEM82 transmembrane protein 82 -2.80219
VWA3B von Willebrand factor A domain containing 3B -2.80219
SIM1 single-minded family bHLH transcription factor 1 -2.80219
MYZAP myocardial zonula adherens protein -2.80219
RASD1 RAS, dexamethasone-induced 1 -2.80219
PDE11A phosphodiesterase 11A -2.79018
OAF OAF homolog (Drosophila) -2.68076
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.67874
DYNLT5 dynein light chain Tctex-type family member 5 -2.67874
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) -2.67186
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 -2.64807
LRRC75A leucine rich repeat containing 75A -2.61436
GRAMD1C GRAM domain containing 1C -2.61436
SH2D5 SH2 domain containing 5 -2.612
ZC3H11A zinc finger CCCH-type containing 11A -2.56363
SLC35B3 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3 -2.54361
COMT catechol-O-methyltransferase -2.5285
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 -2.51383
DNAH5 dynein, axonemal, heavy chain 5 -2.51171
C14ORF93 chromosome 14 open reading frame 93 -2.50444
ADAT3 adenosine deaminase, tRNA-specific 3 -2.48023
GBX1 gastrulation brain homeobox 1 -2.48023
RBM43 RNA binding motif protein 43 -2.45602
SIPA1L3 signal-induced proliferation-associated 1 like 3 -2.45602
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast) -2.4487
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1 -2.4487
WDR11 WD repeat domain 11 -2.42906
C1QTNF1 C1q and tumor necrosis factor related protein 1 -2.399
FDXACB1 ferredoxin-fold anticodon binding domain containing 1 -2.399
KLK6 kallikrein-related peptidase 6 -2.399
ACTR3C ARP3 actin-related protein 3 homolog C (yeast) -2.399
ECE2 endothelin converting enzyme 2 -2.399
BICDL1 BICD family like cargo adaptor 1 -2.38158
FBXO3 F-box protein 3 -2.3006
DNM2 dynamin 2 -2.2835
PDCD10 programmed cell death 10 -2.2835
CANT1 calcium activated nucleotidase 1 -2.28163
GKAP1 G kinase anchoring protein 1 -2.26432
MTRF1 mitochondrial translational release factor 1 -2.19973
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -2.17608
ZNF276 zinc finger protein 276 -2.17608
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 -2.10655
CCNA2 cyclin A2 -2.1048
SEC23B Sec23 homolog B (S. cerevisiae) -2.10044
NHLRC3 NHL repeat containing 3 -2.08755
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 -2.08597
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial -2.08597
RAB39A RAB39A, member RAS oncogene family -2.08324
RBM46 RNA binding motif protein 46 -2.07299
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like -2.07214
RFC5 replication factor C (activator 1) 5, 36.5kDa -2.07214
CLN3 ceroid-lipofuscinosis, neuronal 3 -2.07214
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 -2.0407
SCARF1 scavenger receptor class F, member 1 -2.0407
DCLK3 doublecortin-like kinase 3 -2.0407