NMI Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description N-myc (and STAT) interactor|NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 9111)
External Link http://www.ncbi.nlm.nih.gov/gene/9111
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Genes

53 interacting proteins for NMI from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ACTA1 actin, alpha 1, skeletal muscle
APEH acylaminoacyl-peptide hydrolase
BRCA1 breast cancer 1, early onset
BRMS1 breast cancer metastasis suppressor 1
CDKN2A cyclin-dependent kinase inhibitor 2A
CREBBP CREB binding protein
CYHR1 cysteine/histidine-rich 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DSTN destrin (actin depolymerizing factor)
EMILIN1 elastin microfibril interfacer 1
EXOSC4 exosome component 4
FAM60A family with sequence similarity 60, member A
FOS FBJ murine osteosarcoma viral oncogene homolog
GCSH glycine cleavage system protein H (aminomethyl carrier)
H1FX H1 histone family, member X
HDDC3 HD domain containing 3
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HHLA3 HERV-H LTR-associating 3
HIST1H1B histone cluster 1, H1b
HOXC9 homeobox C9
IFI35 interferon-induced protein 35
IRF7 interferon regulatory factor 7
KAT5 K(lysine) acetyltransferase 5
KDM1A lysine (K)-specific demethylase 1A
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit
NECAP2 NECAP endocytosis associated 2
OXR1 oxidation resistance 1
POLR1B polymerase (RNA) I polypeptide B, 128kDa
POMZP3 POM121 and ZP3 fusion
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMG3 proteasome (prosome, macropain) assembly chaperone 3
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
SCEL sciellin
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SOX10 SRY (sex determining region Y)-box 10
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TBCD tubulin folding cofactor D
TOLLIP toll interacting protein
TRAF5 TNF receptor-associated factor 5
TRIP12 thyroid hormone receptor interactor 12
TUBA3C tubulin, alpha 3c
UBC ubiquitin C
UBE2I ubiquitin-conjugating enzyme E2I
VPS26A vacuolar protein sorting 26 homolog A (S. pombe)