| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/9893924 |
| Similar Terms | |
| Downloads & Tools |
197 proteins with high or low expression in NNC 26-9100 relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL14A1 | collagen, type XIV, alpha 1 | 6.37 |
| CHURC1 | churchill domain containing 1 | 1.56 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | 1.5 |
| PIP | prolactin-induced protein | 1.42 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 1.37 |
| NUTF2 | nuclear transport factor 2 | 1.34 |
| NDUFS8 | NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) | 1.27 |
| MT1X | metallothionein 1X | 1.24 |
| FAM136A | family with sequence similarity 136, member A | 1.24 |
| CHP1 | calcineurin-like EF-hand protein 1 | 1.19 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 1.15 |
| MYO3A | myosin IIIA | 1.09 |
| PDCD6 | programmed cell death 6 | 1.01 |
| NDUFS6 | NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) | 1.0 |
| RABIF | RAB interacting factor | 1.0 |
| MAZ | MYC-associated zinc finger protein (purine-binding transcription factor) | 0.99 |
| SEMG2 | semenogelin II | 0.98 |
| COX5B | cytochrome c oxidase subunit Vb | 0.96 |
| PXN | paxillin | 0.95 |
| ADGRE2 | adhesion G protein-coupled receptor E2 | 0.94 |
| LYPLA2 | lysophospholipase II | 0.93 |
| MT1L | metallothionein 1L (gene/pseudogene) | 0.92 |
| ZPR1 | ZPR1 zinc finger | 0.91 |
| RNASE4 | ribonuclease, RNase A family, 4 | 0.9 |
| MT2A | metallothionein 2A | 0.87 |
| SKA3 | spindle and kinetochore associated complex subunit 3 | 0.86 |
| HPCAL4 | hippocalcin like 4 | 0.85 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.84 |
| RNF220 | ring finger protein 220 | 0.83 |
| DNLZ | DNL-type zinc finger | 0.82 |
| NAAA | N-acylethanolamine acid amidase | 0.81 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.79 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 | 0.77 |
| CALB2 | calbindin 2 | 0.76 |
| SIRT3 | sirtuin 3 | 0.76 |
| DDT | D-dopachrome tautomerase | 0.75 |
| STMN2 | stathmin 2 | 0.75 |
| PRKCG | protein kinase C, gamma | 0.75 |
| CCS | copper chaperone for superoxide dismutase | 0.75 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.75 |
| PGLS | 6-phosphogluconolactonase | 0.75 |
| CRTC3 | CREB regulated transcription coactivator 3 | 0.73 |
| ELP5 | elongator acetyltransferase complex subunit 5 | 0.73 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | 0.72 |
| SELENOF | selenoprotein F | 0.71 |
| ANKRD40 | ankyrin repeat domain 40 | 0.71 |
| LIMD1 | LIM domains containing 1 | 0.71 |
| VSNL1 | visinin-like 1 | 0.69 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.69 |
| EIF1AD | eukaryotic translation initiation factor 1A domain containing | 0.68 |
| RNF14 | ring finger protein 14 | 0.67 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | 0.67 |
| PRKCSH | protein kinase C substrate 80K-H | 0.67 |
| ZNHIT3 | zinc finger, HIT-type containing 3 | 0.66 |
| MT-ND4 | NADH dehydrogenase, subunit 4 (complex I) | 0.66 |
| TXN2 | thioredoxin 2 | 0.66 |
| ALG6 | ALG6, alpha-1,3-glucosyltransferase | 0.66 |
| GINS3 | GINS complex subunit 3 (Psf3 homolog) | 0.65 |
| TPM4 | tropomyosin 4 | 0.65 |
| FASTK | Fas-activated serine/threonine kinase | 0.65 |
| MED4 | mediator complex subunit 4 | 0.64 |
| CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant | 0.63 |
| ALMS1 | Alstrom syndrome protein 1 | 0.63 |
| LASP1 | LIM and SH3 protein 1 | 0.63 |
| HSPB1 | heat shock 27kDa protein 1 | 0.63 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.62 |
| TIPIN | TIMELESS interacting protein | 0.62 |
| ADI1 | acireductone dioxygenase 1 | 0.62 |
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.62 |
| BAG3 | BCL2-associated athanogene 3 | 0.62 |
| SP100 | SP100 nuclear antigen | 0.61 |
| SEPHS1 | selenophosphate synthetase 1 | 0.61 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.61 |
| UROS | uroporphyrinogen III synthase | 0.61 |
| RXRG | retinoid X receptor, gamma | 0.61 |
| NAXE | NAD(P)HX epimerase | 0.61 |
| EPS15L1 | epidermal growth factor receptor pathway substrate 15-like 1 | 0.61 |
| SOD1 | superoxide dismutase 1, soluble | 0.61 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.6 |
| PHPT1 | phosphohistidine phosphatase 1 | 0.6 |
| RTN1 | reticulon 1 | 0.6 |
| PPP1R35 | protein phosphatase 1, regulatory subunit 35 | 0.59 |
| CEPT1 | choline/ethanolamine phosphotransferase 1 | 0.59 |
| PER2 | period circadian clock 2 | 0.59 |
| ISCA2 | iron-sulfur cluster assembly 2 | 0.59 |
| ACY1 | aminoacylase 1 | 0.59 |
| LZIC | leucine zipper and CTNNBIP1 domain containing | 0.59 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.59 |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) | 0.58 |
| ZWINT | ZW10 interacting kinetochore protein | 0.58 |
| STMN1 | stathmin 1 | 0.58 |
| PDCD5 | programmed cell death 5 | 0.58 |
| HEBP2 | heme binding protein 2 | 0.58 |
| REPIN1 | replication initiator 1 | 0.58 |
| PNPO | pyridoxamine 5'-phosphate oxidase | 0.57 |
| RPA3 | replication protein A3, 14kDa | 0.57 |
| ACTBL2 | actin, beta-like 2 | 0.57 |
| RNF13 | ring finger protein 13 | 0.57 |
| PSAP | prosaposin | 0.56 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF317 | zinc finger protein 317 | -2.28 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | -1.91 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | -1.41 |
| PRXL2C | peroxiredoxin like 2C | -1.37 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -1.35 |
| TSPAN3 | tetraspanin 3 | -1.32 |
| CCAR2 | cell cycle and apoptosis regulator 2 | -1.2 |
| HSP90AA4P | heat shock protein 90kDa alpha (cytosolic), class A member 4, pseudogene | -1.06 |
| CD151 | CD151 molecule (Raph blood group) | -0.93 |
| TGDS | TDP-glucose 4,6-dehydratase | -0.89 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | -0.85 |
| TMEM59 | transmembrane protein 59 | -0.85 |
| ABLIM3 | actin binding LIM protein family, member 3 | -0.85 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | -0.81 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.78 |
| SP140 | SP140 nuclear body protein | -0.78 |
| BLOC1S4 | biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino | -0.77 |
| LTBR | lymphotoxin beta receptor (TNFR superfamily, member 3) | -0.76 |
| HSPA8 | heat shock 70kDa protein 8 | -0.73 |
| GMPR | guanosine monophosphate reductase | -0.71 |
| S100A11 | S100 calcium binding protein A11 | -0.71 |
| CD63 | CD63 molecule | -0.71 |
| AREG | amphiregulin | -0.7 |
| MACROD1 | MACRO domain containing 1 | -0.66 |
| ITM2B | integral membrane protein 2B | -0.65 |
| DHFR | dihydrofolate reductase | -0.65 |
| BOK | BCL2-related ovarian killer | -0.62 |
| EGFL7 | EGF-like-domain, multiple 7 | -0.61 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | -0.61 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.6 |
| LRP10 | low density lipoprotein receptor-related protein 10 | -0.6 |
| SGCE | sarcoglycan, epsilon | -0.59 |
| TSPAN6 | tetraspanin 6 | -0.59 |
| PHF13 | PHD finger protein 13 | -0.57 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.56 |
| PGK2 | phosphoglycerate kinase 2 | -0.56 |
| CYCS | cytochrome c, somatic | -0.55 |
| C15ORF40 | chromosome 15 open reading frame 40 | -0.54 |
| VWA3B | von Willebrand factor A domain containing 3B | -0.53 |
| ZNF675 | zinc finger protein 675 | -0.53 |
| TMED3 | transmembrane emp24 protein transport domain containing 3 | -0.52 |
| MIEF2 | mitochondrial elongation factor 2 | -0.52 |
| SRSF3 | serine/arginine-rich splicing factor 3 | -0.52 |
| C20ORF27 | chromosome 20 open reading frame 27 | -0.51 |
| RHOC | ras homolog family member C | -0.51 |
| NFIA | nuclear factor I/A | -0.51 |
| SNRPF | small nuclear ribonucleoprotein polypeptide F | -0.51 |
| SET | SET nuclear proto-oncogene | -0.5 |
| ARHGEF35 | Rho guanine nucleotide exchange factor (GEF) 35 | -0.5 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.5 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | -0.5 |
| FGA | fibrinogen alpha chain | -0.49 |
| NEDD8 | neural precursor cell expressed, developmentally down-regulated 8 | -0.49 |
| KIAA0556 | KIAA0556 | -0.49 |
| CTBP2 | C-terminal binding protein 2 | -0.49 |
| EREG | epiregulin | -0.49 |
| YBX3 | Y box binding protein 3 | -0.48 |
| SLC25A52 | solute carrier family 25, member 52 | -0.46 |
| UCK1 | uridine-cytidine kinase 1 | -0.46 |
| DENND3 | DENN/MADD domain containing 3 | -0.46 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.44 |
| PLBD2 | phospholipase B domain containing 2 | -0.44 |
| RPS27A | ribosomal protein S27a | -0.44 |
| SDC4 | syndecan 4 | -0.43 |
| UBE2Z | ubiquitin-conjugating enzyme E2Z | -0.43 |
| TIMM13 | translocase of inner mitochondrial membrane 13 homolog (yeast) | -0.43 |
| FBXL19 | F-box and leucine-rich repeat protein 19 | -0.43 |
| DLG2 | discs, large homolog 2 (Drosophila) | -0.42 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.42 |
| SOCS2 | suppressor of cytokine signaling 2 | -0.42 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.42 |
| HSPA2 | heat shock 70kDa protein 2 | -0.42 |
| ZDHHC23 | zinc finger, DHHC-type containing 23 | -0.41 |
| F2 | coagulation factor II (thrombin) | -0.41 |
| KLHL18 | kelch-like family member 18 | -0.41 |
| ABI1 | abl-interactor 1 | -0.41 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated | -0.41 |
| CCNG1 | cyclin G1 | -0.41 |
| CRYM | crystallin, mu | -0.41 |
| SDC1 | syndecan 1 | -0.4 |
| FBXL6 | F-box and leucine-rich repeat protein 6 | -0.4 |
| ZNF12 | zinc finger protein 12 | -0.4 |
| RBP7 | retinol binding protein 7, cellular | -0.4 |
| GMPR2 | guanosine monophosphate reductase 2 | -0.4 |
| C5ORF30 | chromosome 5 open reading frame 30 | -0.39 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | -0.39 |
| METAP1 | methionyl aminopeptidase 1 | -0.39 |
| RTN2 | reticulon 2 | -0.39 |
| BAK1 | BCL2-antagonist/killer 1 | -0.39 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.39 |
| TK2 | thymidine kinase 2, mitochondrial | -0.39 |
| JOSD1 | Josephin domain containing 1 | -0.39 |
| PRXL2A | peroxiredoxin like 2A | -0.38 |
| COL2A1 | collagen, type II, alpha 1 | -0.38 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | -0.38 |
| FOXM1 | forkhead box M1 | -0.38 |
| CTSV | cathepsin V | -0.38 |
| DYNC2LI1 | dynein, cytoplasmic 2, light intermediate chain 1 | -0.38 |
