NOBOX Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description NOBOX oogenesis homeobox|This homeobox gene encodes a transcription factor that is thought to play a role in oogenesis. In mice, it is essential for folliculogenesis and regulation of oocyte-specific genes. Defects in this gene result in premature ovarian failure type 5.[provided by RefSeq, May 2011] (NCBI Entrez Gene Database, 135935)
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Genes

275 genes differentially expressed following the NOBOX gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
TBX20 T-box 20 3.10526
TBX15 T-box 15 3.10526
SLC25A41 solute carrier family 25, member 41 3.10526
CXORF65 chromosome X open reading frame 65 3.10526
SH2D7 SH2 domain containing 7 3.10526
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 3.10526
PAX3 paired box 3 3.10526
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13 3.10526
PLCH2 phospholipase C, eta 2 3.10526
CELA3B chymotrypsin-like elastase family, member 3B 3.10526
TMEM176B transmembrane protein 176B 3.10526
NANOS3 nanos homolog 3 (Drosophila) 3.10526
MEP1A meprin A, alpha (PABA peptide hydrolase) 3.10526
TAS2R5 taste receptor, type 2, member 5 3.10526
PDILT protein disulfide isomerase-like, testis expressed 3.10526
COL19A1 collagen, type XIX, alpha 1 3.10526
TMEM212 transmembrane protein 212 3.10526
DNAJC5G DnaJ (Hsp40) homolog, subfamily C, member 5 gamma 3.10526
SLC46A2 solute carrier family 46, member 2 3.10526
IGFL2 IGF-like family member 2 3.10526
FOLR3 folate receptor 3 (gamma) 3.10526
KCNRG potassium channel regulator 3.10526
MPO myeloperoxidase 3.10526
SLC39A12 solute carrier family 39 (zinc transporter), member 12 3.10526
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 3.10526
MRC1 mannose receptor, C type 1 3.10526
VCX variable charge, X-linked 3.10526
CPLX1 complexin 1 3.10526
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 3.10526
NWD1 NACHT and WD repeat domain containing 1 3.10526
ATOH1 atonal homolog 1 (Drosophila) 3.10526
MMP20 matrix metallopeptidase 20 3.10526
WNT8B wingless-type MMTV integration site family, member 8B 3.10526
BIRC7 baculoviral IAP repeat containing 7 3.10526
SFTPC surfactant protein C 3.10526
PTGER4 prostaglandin E receptor 4 (subtype EP4) 3.10526
MOGAT3 monoacylglycerol O-acyltransferase 3 3.10526
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3 3.10526
FABP12 fatty acid binding protein 12 3.10526
S100A9 S100 calcium binding protein A9 3.10526
TMEM121 transmembrane protein 121 3.10526
SPAG8 sperm associated antigen 8 3.10526
INO80D INO80 complex subunit D 3.10526
CSNK2A2IP casein kinase 2 subunit alpha' interacting protein 3.10526
GPR35 G protein-coupled receptor 35 3.10526
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal 3.10526
FIMP1 fertilization-influencing membrane protein 1 3.10526
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 3.10526
LMNTD2 lamin tail domain containing 2 3.10526
PIRT phosphoinositide-interacting regulator of transient receptor potential channels 3.10526
ASB4 ankyrin repeat and SOCS box containing 4 3.10526
DOK2 docking protein 2, 56kDa 3.10526
GBP3 guanylate binding protein 3 3.10526
H2BC1 H2B clustered histone 1 3.10526
FYB1 FYN binding protein 1 3.10526
SPEGNB SPEG neighbor 3.10526
DPEP2NB DPEP2 neighbor 3.10526
LRRC8C-DT LRRC8C divergent transcript 3.10526
CFAP97D2 CFAP97 domain containing 2 3.10526
SRARP steroid receptor associated and regulated protein 3.10526
CD8B2 CD8b2 molecule 3.10526
MEIOSIN meiosis initiator 3.10526
CABCOCO1 ciliary associated calcium binding coiled-coil 1 3.10526
GCSAM germinal center-associated, signaling and motility 3.10526
HTR3C 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic 3.10526
TLR4 toll-like receptor 4 3.10526
SCRT2 scratch family zinc finger 2 3.10526
SIM2 single-minded family bHLH transcription factor 2 3.10526
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 3.10526
MSX2 msh homeobox 2 3.10526
CATSPER3 cation channel, sperm associated 3 3.10526
LOC124906892 uncharacterized LOC124906892 3.10526
THPO thrombopoietin 3.10526
MIP major intrinsic protein of lens fiber 3.10526
TBX3 T-box 3 3.10526
C1QL2 complement component 1, q subcomponent-like 2 3.10526
SYT15 synaptotagmin XV 3.10526
CNTN6 contactin 6 3.10526
DLK2 delta-like 2 homolog (Drosophila) 3.10526
GDF9 growth differentiation factor 9 3.10526
PLEK2 pleckstrin 2 3.10526
FGFBP1 fibroblast growth factor binding protein 1 3.10526
TIMD4 T-cell immunoglobulin and mucin domain containing 4 3.10526
S100B S100 calcium binding protein B 3.10526
DAO D-amino-acid oxidase 3.10526
FAM9C family with sequence similarity 9, member C 3.10526
MAGEA2B melanoma antigen family A2B 3.10526
DMTN dematin actin binding protein 3.10526
RNASE11 ribonuclease, RNase A family, 11 (non-active) 3.10526
GOLGA6B golgin A6 family, member B 3.10526
OR13A1 olfactory receptor, family 13, subfamily A, member 1 3.10526
C11ORF16 chromosome 11 open reading frame 16 3.10526
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 3.10526
NUTM2B NUT family member 2B 3.10526
NUTM2A NUT family member 2A 3.10526
APOC2 apolipoprotein C-II 3.10526
CLCA4 chloride channel accessory 4 3.10526
APOL6 apolipoprotein L, 6 3.10526
APOC4 apolipoprotein C-IV 3.10526
DHRS7C dehydrogenase/reductase (SDR family) member 7C 3.10526
NANOGNB NANOG neighbor homeobox 3.10526
LRRC4C leucine rich repeat containing 4C 3.10526
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 3.10526
PCDHGB2 protocadherin gamma subfamily B, 2 3.10526
LRRC46 leucine rich repeat containing 46 3.10526
KCNK7 potassium channel, two pore domain subfamily K, member 7 3.10526
ZNF132 zinc finger protein 132 3.10526
IGFBP1 insulin-like growth factor binding protein 1 3.10526
ERICH3 glutamate-rich 3 3.10526
OR6C75 olfactory receptor, family 6, subfamily C, member 75 3.10526
ZMYND15 zinc finger, MYND-type containing 15 3.10526
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6 3.10526
TSPAN32 tetraspanin 32 3.10526
MAMLD1 mastermind-like domain containing 1 3.10526
DRD2 dopamine receptor D2 3.10526
ZBED6 zinc finger, BED-type containing 6 3.10526
NLRP9 NLR family, pyrin domain containing 9 3.10526
ASCL5 achaete-scute family bHLH transcription factor 5 3.10526
ADGRD1 adhesion G protein-coupled receptor D1 3.10526
AMPD1 adenosine monophosphate deaminase 1 3.10526
BCL2L15 BCL2-like 15 3.10526
RGS4 regulator of G-protein signaling 4 3.10526
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 3.10526
OPALIN oligodendrocytic myelin paranodal and inner loop protein 3.10526
LHX1 LIM homeobox 1 3.10526
CLEC18B C-type lectin domain family 18, member B 3.10526
PMCH pro-melanin-concentrating hormone 3.10526
KRTAP5-7 keratin associated protein 5-7 3.10526
GPR61 G protein-coupled receptor 61 3.10526
CLDN34 claudin 34 3.10526
GRAPL GRB2-related adaptor protein-like 3.10526
DMRTC2 DMRT-like family C2 3.10526
PCDHGA4 protocadherin gamma subfamily A, 4 3.10526
ISLR immunoglobulin superfamily containing leucine-rich repeat 3.10526
MSLN mesothelin 3.10526
THEM5 thioesterase superfamily member 5 3.10526
ZNF80 zinc finger protein 80 3.10526
FBXO40 F-box protein 40 3.10526
PPP1R3G protein phosphatase 1, regulatory subunit 3G 3.10526
GSTA2 glutathione S-transferase alpha 2 3.10526
CRHBP corticotropin releasing hormone binding protein 3.10526
TRAF3IP3 TRAF3 interacting protein 3 3.10526
LRRC26 leucine rich repeat containing 26 3.10526
NIPA2 non imprinted in Prader-Willi/Angelman syndrome 2 3.07323
MID1IP1 MID1 interacting protein 1 3.06797
IGSF10 immunoglobulin superfamily, member 10 3.04986
CCDC50 coiled-coil domain containing 50 2.92589
PDLIM5 PDZ and LIM domain 5 2.90587
CREG1 cellular repressor of E1A-stimulated genes 1 2.81548
UBAP1 ubiquitin associated protein 1 2.6558
NOL9 nucleolar protein 9 2.64537
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 2.50586
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 2.49002
LARP6 La ribonucleoprotein domain family, member 6 2.47646
ACSS3 acyl-CoA synthetase short-chain family member 3 2.45398
DNAH9 dynein, axonemal, heavy chain 9 2.41446
TAFAZZIN tafazzin, phospholipid-lysophospholipid transacylase 2.40496
OXTR oxytocin receptor 2.36736
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 2.36428
NMBR neuromedin B receptor 2.36428
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 2.35686
USP38 ubiquitin specific peptidase 38 2.35225
ZNF804B zinc finger protein 804B 2.32551
PITX2 paired-like homeodomain 2 2.32551
TMEM86B transmembrane protein 86B 2.32551
MASTL microtubule associated serine/threonine kinase-like 2.32551
PADI1 peptidyl arginine deiminase, type I 2.32551
C2ORF92 chromosome 2 open reading frame 92 2.31307
LMNA lamin A/C 2.30168
ZNF546 zinc finger protein 546 2.28474
STAB2 stabilin 2 2.28072
NES nestin 2.28072
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma 2.25741
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 2.25741
HAVCR2 hepatitis A virus cellular receptor 2 2.2271
ZYG11B zyg-11 family member B, cell cycle regulator 2.20679
PHAF1 phagosome assembly factor 1 2.20679
MIA2 melanoma inhibitory activity 2 2.19931
SPATC1 spermatogenesis and centriole associated 1 2.1904
SIX1 SIX homeobox 1 2.1904
VENTX VENT homeobox 2.1904
FKBP6 FK506 binding protein 6, 36kDa 2.1904
POU5F1 POU class 5 homeobox 1 2.17164
MXD3 MAX dimerization protein 3 2.17043
MPHOSPH6 M-phase phosphoprotein 6 2.17043
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase 2.13178
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 2.12314
NOTCH1 notch 1 2.10911
ITFG2 integrin alpha FG-GAP repeat containing 2 2.09472
SLC35A5 solute carrier family 35, member A5 2.07197
FANCG Fanconi anemia, complementation group G 2.07197
KIAA2012 KIAA2012 2.06541
ZNF248 zinc finger protein 248 2.0517
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 2.04322
CDC34 cell division cycle 34 2.04241
WRAP73 WD repeat containing, antisense to TP73 2.0339
LOXL1 lysyl oxidase-like 1 2.0339
BEGAIN brain-enriched guanylate kinase-associated 2.03358
EXO1 exonuclease 1 2.01954

decreased expression

Symbol Name Standardized Value
SMKR1 small lysine-rich protein 1 -3.10526
AKAP5 A kinase (PRKA) anchor protein 5 -3.10526
ECSIT ECSIT signalling integrator -3.10526
TBX6 T-box 6 -3.10526
MATK megakaryocyte-associated tyrosine kinase -3.10526
TGM2 transglutaminase 2 -3.10526
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha -3.10526
IPO8 importin 8 -2.98691
RAPSN receptor-associated protein of the synapse -2.96392
KLHL34 kelch-like family member 34 -2.96392
PRSS21 protease, serine, 21 (testisin) -2.96392
VSTM2A V-set and transmembrane domain containing 2A -2.96392
FGF23 fibroblast growth factor 23 -2.96392
TMEM151A transmembrane protein 151A -2.96392
SCN2B sodium channel, voltage gated, type II beta subunit -2.96392
AKR1C2 aldo-keto reductase family 1, member C2 -2.96392
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) -2.96392
PLIN4 perilipin 4 -2.96392
GLRA3 glycine receptor, alpha 3 -2.96392
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 -2.96392
LRRIQ4 leucine-rich repeats and IQ motif containing 4 -2.96392
TMEM215 transmembrane protein 215 -2.96392
ELAVL4 ELAV like neuron-specific RNA binding protein 4 -2.96392
BNC1 basonuclin 1 -2.96392
MYPN myopalladin -2.96392
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -2.96392
PRDM6 PR domain containing 6 -2.96392
ZGLP1 zinc finger, GATA-like protein 1 -2.96392
C11ORF96 chromosome 11 open reading frame 96 -2.96392
PRAP1 proline-rich acidic protein 1 -2.96392
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 -2.96392
ACSM1 acyl-CoA synthetase medium-chain family member 1 -2.96392
IAPP islet amyloid polypeptide -2.96392
IRF4 interferon regulatory factor 4 -2.96392
SP100 SP100 nuclear antigen -2.96392
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic -2.96392
VPS26B vacuolar protein sorting 26 homolog B (S. pombe) -2.96045
SMC6 structural maintenance of chromosomes 6 -2.96045
PCDHGA6 protocadherin gamma subfamily A, 6 -2.94311
ZBTB48 zinc finger and BTB domain containing 48 -2.85934
ZNHIT6 zinc finger, HIT-type containing 6 -2.64593
NKD2 naked cuticle homolog 2 (Drosophila) -2.62742
PPP1R9B protein phosphatase 1, regulatory subunit 9B -2.55148
CLEC2L C-type lectin domain family 2, member L -2.53512
TEN1 TEN1 CST complex subunit -2.53168
DCDC2 doublecortin domain containing 2 -2.47646
LYSMD1 LysM, putative peptidoglycan-binding, domain containing 1 -2.44281
PCP4L1 Purkinje cell protein 4 like 1 -2.43804
CCDC170 coiled-coil domain containing 170 -2.43804
CCDC60 coiled-coil domain containing 60 -2.43804
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta -2.40496
TYRO3 TYRO3 protein tyrosine kinase -2.35644
AFG2A AFG2 AAA ATPase homolog A -2.35206
METTL24 methyltransferase like 24 -2.32002
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa -2.32002
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 -2.32002
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) -2.29188
DAXX death-domain associated protein -2.28758
WTAP Wilms tumor 1 associated protein -2.24846
PKD1L3 polycystic kidney disease 1-like 3 -2.2273
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) -2.21772
FAM168A family with sequence similarity 168, member A -2.20679
PPM1N protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative) -2.20309
MRPL3 mitochondrial ribosomal protein L3 -2.19931
SEPTIN6 septin 6 -2.17167
INTS12 integrator complex subunit 12 -2.15297
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) -2.12064
ZMYND8 zinc finger, MYND-type containing 8 -2.11165
PLPP6 phospholipid phosphatase 6 -2.11137
YIF1B Yip1 interacting factor homolog B (S. cerevisiae) -2.07197
TFAP2E transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon) -2.06165
COL8A1 collagen, type VIII, alpha 1 -2.06165
SGCZ sarcoglycan, zeta -2.05423
NEDD1 neural precursor cell expressed, developmentally down-regulated 1 -2.0517
ANAPC4 anaphase promoting complex subunit 4 -2.0462
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 -2.01334