| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | nucleotide-binding oligomerization domain containing 1|This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Oct 2009] (NCBI Entrez Gene Database, 10392) |
| External Link | https://ncbi.nlm.nih.gov/gene/10392 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the NOD1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | 0.0159136 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0138023 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0132026 |
| HOPX | HOP homeobox | 0.0128892 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.0125857 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.0117199 |
| APOD | apolipoprotein D | 0.011631 |
| WASHC4 | WASH complex subunit 4 | 0.0113001 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0110855 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.0108062 |
| TPSAB1 | tryptase alpha/beta 1 | 0.0106034 |
| GUSB | glucuronidase, beta | 0.0102037 |
| KRT7 | keratin 7, type II | 0.00969939 |
| NAV2 | neuron navigator 2 | 0.00968654 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | 0.00962951 |
| FASN | fatty acid synthase | 0.00962449 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.00959882 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 0.00951261 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 | 0.00911397 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00907724 |
| PRKCZ | protein kinase C, zeta | 0.00907086 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.009017 |
| CROCCP2 | ciliary rootlet coiled-coil, rootletin pseudogene 2 | 0.00898639 |
| PLXNA1 | plexin A1 | 0.00892157 |
| PYGB | phosphorylase, glycogen; brain | 0.00861205 |
| RIN2 | Ras and Rab interactor 2 | 0.00858376 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.0085738 |
| TGFB1 | transforming growth factor, beta 1 | 0.00854483 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00850709 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00844634 |
| TBX3 | T-box 3 | 0.00839002 |
| KRT17 | keratin 17, type I | 0.00836039 |
| CCNA2 | cyclin A2 | 0.00835919 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0083291 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | 0.0083237 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.00830776 |
| PRAME | preferentially expressed antigen in melanoma | 0.00821518 |
| PROS1 | protein S (alpha) | 0.00814449 |
| GSDME | gasdermin E | 0.00810446 |
| DKFZP586I1420 | uncharacterized protein DKFZp586I1420 | 0.0080699 |
| MSMB | microseminoprotein, beta- | 0.008002 |
| IRS2 | insulin receptor substrate 2 | 0.00798411 |
| MMP1 | matrix metallopeptidase 1 | 0.00797525 |
| GOLGA8A | golgin A8 family, member A | 0.00796564 |
| ENAH | enabled homolog (Drosophila) | 0.00796437 |
| PMP22 | peripheral myelin protein 22 | 0.00796013 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.00793471 |
| KRT14 | keratin 14, type I | 0.0079081 |
| VEGFA | vascular endothelial growth factor A | 0.00789912 |
| COCH | cochlin | 0.0078244 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.00781093 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.00779446 |
| TXLNA | taxilin alpha | 0.00777844 |
| GGT1 | gamma-glutamyltransferase 1 | 0.00777335 |
| KLK2 | kallikrein-related peptidase 2 | 0.00776025 |
| NSUN5P1 | NOP2/Sun domain family, member 5 pseudogene 1 | 0.0077557 |
| BGN | biglycan | 0.00774351 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.00771161 |
| LBH | limb bud and heart development | 0.00768016 |
| CD320 | CD320 molecule | 0.00766507 |
| MICALL2 | MICAL-like 2 | 0.00766281 |
| PLXNB2 | plexin B2 | 0.00766015 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 0.00765701 |
| PTK2 | protein tyrosine kinase 2 | 0.00759675 |
| BCL7B | B-cell CLL/lymphoma 7B | 0.00759416 |
| PLA1A | phospholipase A1 member A | 0.00758642 |
| NNMT | nicotinamide N-methyltransferase | 0.00756611 |
| PKP1 | plakophilin 1 | 0.00753759 |
| PXDC1 | PX domain containing 1 | 0.00752467 |
| DOCK9 | dedicator of cytokinesis 9 | 0.00748771 |
| STK25 | serine/threonine kinase 25 | 0.00748659 |
| COL7A1 | collagen, type VII, alpha 1 | 0.00748343 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) | 0.00747302 |
| PKD1P1 | polycystic kidney disease 1 (autosomal dominant) pseudogene 1 | 0.00746531 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | 0.00740178 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.00740076 |
| PRKCSH | protein kinase C substrate 80K-H | 0.00739345 |
| MXRA7 | matrix-remodelling associated 7 | 0.00735564 |
| SFTPA2 | surfactant protein A2 | 0.00727613 |
| MMP7 | matrix metallopeptidase 7 | 0.00727268 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | 0.00724555 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.00722892 |
| SPON2 | spondin 2, extracellular matrix protein | 0.00722199 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 0.00719963 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.00718818 |
| SPATA20 | spermatogenesis associated 20 | 0.00715676 |
| SPG7 | spastic paraplegia 7 (pure and complicated autosomal recessive) | 0.0071238 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | 0.0071211 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | 0.00711488 |
| PAX5 | paired box 5 | 0.0071105 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.00710813 |
| TAGLN | transgelin | 0.00709133 |
| NPIPA1 | nuclear pore complex interacting protein family, member A1 | 0.00700595 |
| ZNF512B | zinc finger protein 512B | 0.00699342 |
| EFR3A | EFR3 homolog A (S. cerevisiae) | 0.00694605 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.00693696 |
| GPNMB | glycoprotein (transmembrane) nmb | 0.00693354 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.0069319 |
| TGM2 | transglutaminase 2 | 0.00693182 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | 0.0069231 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.00691799 |
| HIP1R | huntingtin interacting protein 1 related | 0.00688357 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.00686259 |
| CLCN7 | chloride channel, voltage-sensitive 7 | 0.00683865 |
| CD81 | CD81 molecule | 0.00683698 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.00682704 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.00681901 |
| SAFB2 | scaffold attachment factor B2 | 0.00681376 |
| CTBP2 | C-terminal binding protein 2 | 0.00680783 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | 0.00680093 |
| ECM1 | extracellular matrix protein 1 | 0.00679748 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.00679647 |
| SLC38A10 | solute carrier family 38, member 10 | 0.0067916 |
| TMEM63A | transmembrane protein 63A | 0.00678113 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.00677093 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 0.0067435 |
| INTS1 | integrator complex subunit 1 | 0.00673176 |
| SIK1 | salt-inducible kinase 1 | 0.00672091 |
| RAB29 | RAB29, member RAS oncogene family | 0.00671697 |
| FKBP11 | FK506 binding protein 11, 19 kDa | 0.00671635 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.00671541 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 0.00670486 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.00669577 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.00668067 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.00666431 |
| JAG1 | jagged 1 | 0.00665045 |
| CENPT | centromere protein T | 0.00662153 |
| NFIB | nuclear factor I/B | 0.00661154 |
| DGKZ | diacylglycerol kinase, zeta | 0.00660903 |
| KLK3 | kallikrein-related peptidase 3 | 0.00659615 |
| SOCS1 | suppressor of cytokine signaling 1 | 0.00659226 |
| ITGAV | integrin, alpha V | 0.00658002 |
| EML3 | echinoderm microtubule associated protein like 3 | 0.0065745 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00656908 |
| ESYT1 | extended synaptotagmin-like protein 1 | 0.00656615 |
| TES | testin LIM domain protein | 0.00656566 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00654528 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.00654207 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 | 0.00654061 |
| RBM26 | RNA binding motif protein 26 | 0.00652968 |
| MAGED1 | melanoma antigen family D1 | 0.00649892 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.00649018 |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 | 0.00647402 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00645801 |
| COL10A1 | collagen, type X, alpha 1 | 0.00643694 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.00642784 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00641109 |
| PDE10A | phosphodiesterase 10A | 0.00640318 |
| GDF15 | growth differentiation factor 15 | 0.00638887 |
| SFTPB | surfactant protein B | 0.00636982 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | 0.00636621 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.00635943 |
| SLC22A3 | solute carrier family 22 (organic cation transporter), member 3 | 0.00632923 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 | 0.0063245 |
| LAMA5 | laminin, alpha 5 | 0.00631883 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 0.00631024 |
| STAG3 | stromal antigen 3 | 0.00630609 |
| IPO13 | importin 13 | 0.00627954 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.00626906 |
| PERP | PERP, TP53 apoptosis effector | 0.00625457 |
| SPHK1 | sphingosine kinase 1 | 0.00624607 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | 0.00623749 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00623703 |
| GGTLC1 | gamma-glutamyltransferase light chain 1 | 0.00621915 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.00621735 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | 0.00621095 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00620192 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.00619781 |
| HOMER3 | homer scaffolding protein 3 | 0.00619509 |
| TSPYL5 | TSPY-like 5 | 0.00618026 |
| OFD1 | oral-facial-digital syndrome 1 | 0.0061689 |
| TSPAN4 | tetraspanin 4 | 0.00615603 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00615471 |
| TP63 | tumor protein p63 | 0.00615241 |
| COMP | cartilage oligomeric matrix protein | 0.00615108 |
| PILRB | paired immunoglobin-like type 2 receptor beta | 0.00614922 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0061472 |
| NOTCH2NL | notch 2 N-terminal like | 0.0061445 |
| AEBP1 | AE binding protein 1 | 0.00614159 |
| FOLH1B | folate hydrolase 1B | 0.00613355 |
| CORO1B | coronin, actin binding protein, 1B | 0.00612737 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | 0.00611902 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | 0.00611674 |
| WDR13 | WD repeat domain 13 | 0.00611503 |
| FN1 | fibronectin 1 | 0.00611422 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.00611119 |
| TUFT1 | tuftelin 1 | 0.00609086 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.00608669 |
| RGS16 | regulator of G-protein signaling 16 | 0.00608189 |
| SIDT2 | SID1 transmembrane family, member 2 | 0.0060792 |
| NPY | neuropeptide Y | 0.00607646 |
| RANGAP1 | Ran GTPase activating protein 1 | 0.00602873 |
| PLXND1 | plexin D1 | 0.0060058 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00598171 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit | 0.00597768 |
| FAM53B | family with sequence similarity 53, member B | 0.00597061 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.00596505 |
| ATG4B | autophagy related 4B, cysteine peptidase | 0.00595817 |
| PLSCR3 | phospholipid scramblase 3 | 0.00595571 |
| DVL1 | dishevelled segment polarity protein 1 | 0.00594785 |
| CCN3 | cellular communication network factor 3 | 0.00593233 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.00592909 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.00592751 |
| EFHD2 | EF-hand domain family, member D2 | 0.0059265 |
| MARCKSL1 | MARCKS-like 1 | 0.00591699 |
| AGR2 | anterior gradient 2 | 0.00591286 |
| STXBP2 | syntaxin binding protein 2 | 0.00590084 |
| TMC6 | transmembrane channel-like 6 | 0.00589197 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 0.00587581 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | 0.00587058 |
| CLDN1 | claudin 1 | 0.00586972 |
| HERC2 | HECT and RLD domain containing E3 ubiquitin protein ligase 2 | 0.00586266 |
| MAOA | monoamine oxidase A | 0.00586122 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 | 0.00585832 |
| GOLGA8H | golgin A8 family, member H | 0.00584784 |
| MTCL1 | microtubule crosslinking factor 1 | 0.00580688 |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 | 0.00579679 |
| CSPG4 | chondroitin sulfate proteoglycan 4 | 0.00579215 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.00579151 |
| ADCY1 | adenylate cyclase 1 (brain) | 0.00577734 |
| RGL2 | ral guanine nucleotide dissociation stimulator-like 2 | 0.0057629 |
| NSUN5 | NOP2/Sun domain family, member 5 | 0.00576044 |
| UXT | ubiquitously-expressed, prefoldin-like chaperone | 0.00575862 |
| TARP | TCR gamma alternate reading frame protein | 0.00575161 |
| LONP1 | lon peptidase 1, mitochondrial | 0.00574133 |
| MYO6 | myosin VI | 0.00572028 |
| GZMK | granzyme K (granzyme 3; tryptase II) | 0.00571735 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | 0.00571277 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) | 0.00571224 |
| LUM | lumican | 0.0056991 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.00569825 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 | 0.00568345 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.00567657 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.00567025 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.00566828 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0056664 |
| HCRT | hypocretin (orexin) neuropeptide precursor | 0.00565314 |
| SLC38A1 | solute carrier family 38, member 1 | 0.00565075 |
| BCHE | butyrylcholinesterase | 0.00565028 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.00564478 |
| LCAT | lecithin-cholesterol acyltransferase | 0.0056409 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | 0.00563881 |
| PLCB4 | phospholipase C, beta 4 | 0.00563751 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | 0.00563153 |
| GLS | glutaminase | 0.00563077 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 | 0.00562439 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.00561393 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.00560319 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | 0.00560196 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SSBP2 | single-stranded DNA binding protein 2 | -0.0266043 |
| DEFB1 | defensin, beta 1 | -0.0156306 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.0146173 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0142479 |
| BEX1 | brain expressed, X-linked 1 | -0.014152 |
| MAL | mal, T-cell differentiation protein | -0.0139372 |
| DOK5 | docking protein 5 | -0.0122369 |
| SPON1 | spondin 1, extracellular matrix protein | -0.0119585 |
| SST | somatostatin | -0.0115985 |
| AK4 | adenylate kinase 4 | -0.0114331 |
| CA2 | carbonic anhydrase II | -0.0113007 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.0111311 |
| EXOC5 | exocyst complex component 5 | -0.0109309 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | -0.0107456 |
| NREP | neuronal regeneration related protein | -0.0105799 |
| AZIN1 | antizyme inhibitor 1 | -0.0103141 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -0.0102434 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.0102392 |
| S100A7 | S100 calcium binding protein A7 | -0.010198 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.0101797 |
| S100A9 | S100 calcium binding protein A9 | -0.0101689 |
| PEG3 | paternally expressed 3 | -0.00997645 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.00988163 |
| ITM2A | integral membrane protein 2A | -0.00985887 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.00977921 |
| PITX3 | paired-like homeodomain 3 | -0.00965737 |
| CD200 | CD200 molecule | -0.00959657 |
| YIPF5 | Yip1 domain family, member 5 | -0.00956694 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | -0.00949626 |
| HIGD1A | HIG1 hypoxia inducible domain family, member 1A | -0.00926186 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00921232 |
| PEX2 | peroxisomal biogenesis factor 2 | -0.00914514 |
| OLFML3 | olfactomedin-like 3 | -0.00900174 |
| BMP4 | bone morphogenetic protein 4 | -0.00885706 |
| GLUL | glutamate-ammonia ligase | -0.00881454 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.00876403 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00871421 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00866148 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.00860924 |
| TANK | TRAF family member-associated NFKB activator | -0.00857783 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | -0.00854511 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | -0.00853906 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | -0.00853087 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.00849724 |
| AGPS | alkylglycerone phosphate synthase | -0.00847401 |
| TSPAN7 | tetraspanin 7 | -0.00847376 |
| SELL | selectin L | -0.00846809 |
| MECOM | MDS1 and EVI1 complex locus | -0.00844385 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | -0.00842383 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.00841874 |
| KLK8 | kallikrein-related peptidase 8 | -0.00830211 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.00828323 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.00825125 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.00825018 |
| C5ORF30 | chromosome 5 open reading frame 30 | -0.00819015 |
| PLBD1 | phospholipase B domain containing 1 | -0.00818052 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.00816543 |
| SCAMP1 | secretory carrier membrane protein 1 | -0.00811494 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit | -0.00810936 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | -0.00808888 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -0.00807946 |
| COMMD10 | COMM domain containing 10 | -0.00806056 |
| KLK6 | kallikrein-related peptidase 6 | -0.00804562 |
| IL6ST | interleukin 6 signal transducer | -0.00799468 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00795374 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -0.0079163 |
| BEX4 | brain expressed, X-linked 4 | -0.00789734 |
| AOC1 | amine oxidase, copper containing 1 | -0.00786996 |
| CLDN10 | claudin 10 | -0.00786119 |
| SKP1 | S-phase kinase-associated protein 1 | -0.00785375 |
| COX7B | cytochrome c oxidase subunit VIIb | -0.00781257 |
| KCTD20 | potassium channel tetramerization domain containing 20 | -0.0078027 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.00777925 |
| TXN | thioredoxin | -0.00777131 |
| FAM198B | family with sequence similarity 198, member B | -0.0077645 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.00775233 |
| FCGBP | Fc fragment of IgG binding protein | -0.0077345 |
| SELENOT | selenoprotein T | -0.00772464 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | -0.00771456 |
| GCA | grancalcin, EF-hand calcium binding protein | -0.0077052 |
| GPM6B | glycoprotein M6B | -0.00769942 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00769748 |
| FAR2 | fatty acyl CoA reductase 2 | -0.007678 |
| HIST1H2AC | histone cluster 1, H2ac | -0.00765753 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -0.00764133 |
| CFI | complement factor I | -0.00762539 |
| CA12 | carbonic anhydrase XII | -0.00760707 |
| GPC3 | glypican 3 | -0.00759273 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | -0.00755348 |
| EAPP | E2F-associated phosphoprotein | -0.00751131 |
| CEL | carboxyl ester lipase | -0.00750546 |
| STMN2 | stathmin 2 | -0.00749587 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.00749501 |
| ACOX2 | acyl-CoA oxidase 2, branched chain | -0.00747226 |
| PLIN3 | perilipin 3 | -0.00745775 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | -0.00745598 |
| CDC42 | cell division cycle 42 | -0.00744787 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0074 |
| OXTR | oxytocin receptor | -0.00738641 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.00736768 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00735445 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.00734997 |
| KLK7 | kallikrein-related peptidase 7 | -0.00734537 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.00734228 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -0.00727623 |
| CLCA4 | chloride channel accessory 4 | -0.00726841 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.00726268 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | -0.00724888 |
| MUC16 | mucin 16, cell surface associated | -0.00724204 |
| LSM1 | LSM1, U6 small nuclear RNA associated | -0.00720301 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | -0.00719583 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.00717105 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.00713205 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.00712754 |
| TSPAN31 | tetraspanin 31 | -0.00712469 |
| CLIC5 | chloride intracellular channel 5 | -0.00711698 |
| TLR4 | toll-like receptor 4 | -0.00705174 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.00704755 |
| TSPAN3 | tetraspanin 3 | -0.00703906 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | -0.00703373 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.00701335 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 | -0.00700891 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | -0.00700495 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.00698969 |
| PADI2 | peptidyl arginine deiminase, type II | -0.00697687 |
| EIF5 | eukaryotic translation initiation factor 5 | -0.00696386 |
| BTG3 | BTG family, member 3 | -0.0069468 |
| NDUFS4 | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | -0.00690806 |
| ICAM3 | intercellular adhesion molecule 3 | -0.00688932 |
| MED6 | mediator complex subunit 6 | -0.00686418 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.00685981 |
| ESR1 | estrogen receptor 1 | -0.00685846 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.00684915 |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A | -0.00684419 |
| LRRC17 | leucine rich repeat containing 17 | -0.00683785 |
| GHITM | growth hormone inducible transmembrane protein | -0.00681678 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | -0.00680512 |
| NRN1 | neuritin 1 | -0.0067956 |
| FGL2 | fibrinogen-like 2 | -0.0067808 |
| LDB2 | LIM domain binding 2 | -0.00676582 |
| GAB2 | GRB2-associated binding protein 2 | -0.00674315 |
| AK2 | adenylate kinase 2 | -0.00671504 |
| MRPL22 | mitochondrial ribosomal protein L22 | -0.00671184 |
| MAPK14 | mitogen-activated protein kinase 14 | -0.00670101 |
| TMEM47 | transmembrane protein 47 | -0.00668264 |
| IDH3A | isocitrate dehydrogenase 3 (NAD+) alpha | -0.00668021 |
| LASP1 | LIM and SH3 protein 1 | -0.00668002 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.00666246 |
| CHMP2B | charged multivesicular body protein 2B | -0.00664793 |
| UQCRC2 | ubiquinol-cytochrome c reductase core protein II | -0.00660966 |
| EMX2 | empty spiracles homeobox 2 | -0.0066003 |
| EMP1 | epithelial membrane protein 1 | -0.00658561 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00657848 |
| OLFM1 | olfactomedin 1 | -0.00657442 |
| HIPK3 | homeodomain interacting protein kinase 3 | -0.00656886 |
| TFDP1 | transcription factor Dp-1 | -0.00655399 |
| DLAT | dihydrolipoamide S-acetyltransferase | -0.0065339 |
| CES1 | carboxylesterase 1 | -0.00651584 |
| KLK10 | kallikrein-related peptidase 10 | -0.00649223 |
| MEN1 | multiple endocrine neoplasia I | -0.00648118 |
| JPT1 | Jupiter microtubule associated homolog 1 | -0.00647862 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | -0.00647579 |
| MAGT1 | magnesium transporter 1 | -0.00646989 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | -0.00646588 |
| S100A14 | S100 calcium binding protein A14 | -0.00646516 |
| XPO7 | exportin 7 | -0.00645967 |
| MOCS2 | molybdenum cofactor synthesis 2 | -0.00645705 |
| DCTN4 | dynactin 4 (p62) | -0.00644214 |
| ATP5F1C | ATP synthase F1 subunit gamma | -0.00643945 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00643841 |
| S1PR1 | sphingosine-1-phosphate receptor 1 | -0.00642983 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00642976 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | -0.00640217 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00640023 |
| CHEK1 | checkpoint kinase 1 | -0.00637068 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | -0.00636631 |
| PRKCQ | protein kinase C, theta | -0.00635406 |
| GPR183 | G protein-coupled receptor 183 | -0.00635395 |
| TPBG | trophoblast glycoprotein | -0.00633319 |
| TMEM176B | transmembrane protein 176B | -0.00632576 |
| RPA3 | replication protein A3, 14kDa | -0.00631637 |
| DAZAP2 | DAZ associated protein 2 | -0.00630507 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.00626351 |
| DNTT | DNA nucleotidylexotransferase | -0.00625979 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.00623758 |
| SLC39A9 | solute carrier family 39, member 9 | -0.00622996 |
| WDR61 | WD repeat domain 61 | -0.0062291 |
| FKBP5 | FK506 binding protein 5 | -0.00620558 |
| CLU | clusterin | -0.00619686 |
| ARL3 | ADP-ribosylation factor-like 3 | -0.00618594 |
| CRYZ | crystallin, zeta (quinone reductase) | -0.0061835 |
| SRSF1 | serine/arginine-rich splicing factor 1 | -0.00618023 |
| WDR48 | WD repeat domain 48 | -0.00614707 |
| RPL26L1 | ribosomal protein L26-like 1 | -0.00613201 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.00612937 |
| TXNIP | thioredoxin interacting protein | -0.00611943 |
| LYPLA1 | lysophospholipase I | -0.00610964 |
| RHOH | ras homolog family member H | -0.00608645 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.00608586 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.00608162 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00608139 |
| CD59 | CD59 molecule, complement regulatory protein | -0.00607766 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -0.00607408 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.00607295 |
| TSPAN6 | tetraspanin 6 | -0.00605444 |
| SIRT3 | sirtuin 3 | -0.00604428 |
| CTSS | cathepsin S | -0.00604068 |
| DCK | deoxycytidine kinase | -0.00602953 |
| RBBP4 | retinoblastoma binding protein 4 | -0.00602655 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.00602035 |
| TTC1 | tetratricopeptide repeat domain 1 | -0.00599753 |
| TUBB2A | tubulin, beta 2A class IIa | -0.00599423 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -0.00599169 |
| CHODL | chondrolectin | -0.00598651 |
| TMEM176A | transmembrane protein 176A | -0.0059779 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | -0.00597492 |
| RPP14 | ribonuclease P/MRP 14kDa subunit | -0.00596574 |
| RIMBP2 | RIMS binding protein 2 | -0.00596455 |
| TSLIG2 | tRNA splicing ligase complex subunit 2 | -0.00594105 |
| GEMIN2 | gem (nuclear organelle) associated protein 2 | -0.00593925 |
| MRPL18 | mitochondrial ribosomal protein L18 | -0.00593672 |
| CD86 | CD86 molecule | -0.00593055 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 | -0.00592574 |
| CCL14 | chemokine (C-C motif) ligand 14 | -0.00591995 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.00591864 |
| REEP5 | receptor accessory protein 5 | -0.00590327 |
| POT1 | protection of telomeres 1 | -0.00589777 |
| RCAN1 | regulator of calcineurin 1 | -0.00588947 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.00588566 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.00588471 |
| HSPA12A | heat shock 70kDa protein 12A | -0.00588145 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.00587872 |
| HSBP1 | heat shock factor binding protein 1 | -0.00587423 |
| CHMP1B | charged multivesicular body protein 1B | -0.00586642 |
| IRF4 | interferon regulatory factor 4 | -0.00586492 |
| PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | -0.00585539 |
| NAV3 | neuron navigator 3 | -0.00585149 |
| CCDC6 | coiled-coil domain containing 6 | -0.00584784 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 | -0.00582859 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | -0.00577881 |
| TPM4 | tropomyosin 4 | -0.00577222 |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein | -0.00576218 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.00576215 |
| FZD6 | frizzled class receptor 6 | -0.00576009 |
| SOX17 | SRY (sex determining region Y)-box 17 | -0.0057552 |
| COX5B | cytochrome c oxidase subunit Vb | -0.00575188 |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor | -0.00574971 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.0057474 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | -0.00574283 |