NOD1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description nucleotide-binding oligomerization domain containing 1|This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Oct 2009] (NCBI Entrez Gene Database, 10392)
External Link https://ncbi.nlm.nih.gov/gene/10392
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Genes

498 genes differentially expressed following the NOD1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 0.0159136
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.0138023
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.0132026
HOPX HOP homeobox 0.0128892
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.0125857
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.0117199
APOD apolipoprotein D 0.011631
WASHC4 WASH complex subunit 4 0.0113001
BASP1 brain abundant, membrane attached signal protein 1 0.0110855
PIEZO1 piezo-type mechanosensitive ion channel component 1 0.0108062
TPSAB1 tryptase alpha/beta 1 0.0106034
GUSB glucuronidase, beta 0.0102037
KRT7 keratin 7, type II 0.00969939
NAV2 neuron navigator 2 0.00968654
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 0.00962951
FASN fatty acid synthase 0.00962449
DEGS1 delta(4)-desaturase, sphingolipid 1 0.00959882
ADAT1 adenosine deaminase, tRNA-specific 1 0.00951261
RABEP2 rabaptin, RAB GTPase binding effector protein 2 0.00911397
AQP3 aquaporin 3 (Gill blood group) 0.00907724
PRKCZ protein kinase C, zeta 0.00907086
CCL19 chemokine (C-C motif) ligand 19 0.009017
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2 0.00898639
PLXNA1 plexin A1 0.00892157
PYGB phosphorylase, glycogen; brain 0.00861205
RIN2 Ras and Rab interactor 2 0.00858376
AMIGO2 adhesion molecule with Ig-like domain 2 0.0085738
TGFB1 transforming growth factor, beta 1 0.00854483
SAMD4A sterile alpha motif domain containing 4A 0.00850709
IFI6 interferon, alpha-inducible protein 6 0.00844634
TBX3 T-box 3 0.00839002
KRT17 keratin 17, type I 0.00836039
CCNA2 cyclin A2 0.00835919
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.0083291
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 0.0083237
DGKD diacylglycerol kinase, delta 130kDa 0.00830776
PRAME preferentially expressed antigen in melanoma 0.00821518
PROS1 protein S (alpha) 0.00814449
GSDME gasdermin E 0.00810446
DKFZP586I1420 uncharacterized protein DKFZp586I1420 0.0080699
MSMB microseminoprotein, beta- 0.008002
IRS2 insulin receptor substrate 2 0.00798411
MMP1 matrix metallopeptidase 1 0.00797525
GOLGA8A golgin A8 family, member A 0.00796564
ENAH enabled homolog (Drosophila) 0.00796437
PMP22 peripheral myelin protein 22 0.00796013
MET MET proto-oncogene, receptor tyrosine kinase 0.00793471
KRT14 keratin 14, type I 0.0079081
VEGFA vascular endothelial growth factor A 0.00789912
COCH cochlin 0.0078244
TIMP1 TIMP metallopeptidase inhibitor 1 0.00781093
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.00779446
TXLNA taxilin alpha 0.00777844
GGT1 gamma-glutamyltransferase 1 0.00777335
KLK2 kallikrein-related peptidase 2 0.00776025
NSUN5P1 NOP2/Sun domain family, member 5 pseudogene 1 0.0077557
BGN biglycan 0.00774351
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.00771161
LBH limb bud and heart development 0.00768016
CD320 CD320 molecule 0.00766507
MICALL2 MICAL-like 2 0.00766281
PLXNB2 plexin B2 0.00766015
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 0.00765701
PTK2 protein tyrosine kinase 2 0.00759675
BCL7B B-cell CLL/lymphoma 7B 0.00759416
PLA1A phospholipase A1 member A 0.00758642
NNMT nicotinamide N-methyltransferase 0.00756611
PKP1 plakophilin 1 0.00753759
PXDC1 PX domain containing 1 0.00752467
DOCK9 dedicator of cytokinesis 9 0.00748771
STK25 serine/threonine kinase 25 0.00748659
COL7A1 collagen, type VII, alpha 1 0.00748343
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 0.00747302
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 0.00746531
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 0.00740178
RFTN1 raftlin, lipid raft linker 1 0.00740076
PRKCSH protein kinase C substrate 80K-H 0.00739345
MXRA7 matrix-remodelling associated 7 0.00735564
SFTPA2 surfactant protein A2 0.00727613
MMP7 matrix metallopeptidase 7 0.00727268
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 0.00724555
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.00722892
SPON2 spondin 2, extracellular matrix protein 0.00722199
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 0.00719963
ADARB1 adenosine deaminase, RNA-specific, B1 0.00718818
SPATA20 spermatogenesis associated 20 0.00715676
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 0.0071238
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.0071211
SH3BGRL SH3 domain binding glutamate-rich protein like 0.00711488
PAX5 paired box 5 0.0071105
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.00710813
TAGLN transgelin 0.00709133
NPIPA1 nuclear pore complex interacting protein family, member A1 0.00700595
ZNF512B zinc finger protein 512B 0.00699342
EFR3A EFR3 homolog A (S. cerevisiae) 0.00694605
CCL5 chemokine (C-C motif) ligand 5 0.00693696
GPNMB glycoprotein (transmembrane) nmb 0.00693354
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.0069319
TGM2 transglutaminase 2 0.00693182
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 0.0069231
LY6E lymphocyte antigen 6 complex, locus E 0.00691799
HIP1R huntingtin interacting protein 1 related 0.00688357
ACSL1 acyl-CoA synthetase long-chain family member 1 0.00686259
CLCN7 chloride channel, voltage-sensitive 7 0.00683865
CD81 CD81 molecule 0.00683698
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.00682704
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.00681901
SAFB2 scaffold attachment factor B2 0.00681376
CTBP2 C-terminal binding protein 2 0.00680783
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 0.00680093
ECM1 extracellular matrix protein 1 0.00679748
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.00679647
SLC38A10 solute carrier family 38, member 10 0.0067916
TMEM63A transmembrane protein 63A 0.00678113
CD40 CD40 molecule, TNF receptor superfamily member 5 0.00677093
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.0067435
INTS1 integrator complex subunit 1 0.00673176
SIK1 salt-inducible kinase 1 0.00672091
RAB29 RAB29, member RAS oncogene family 0.00671697
FKBP11 FK506 binding protein 11, 19 kDa 0.00671635
EIF3B eukaryotic translation initiation factor 3, subunit B 0.00671541
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.00670486
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.00669577
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.00668067
TACC2 transforming, acidic coiled-coil containing protein 2 0.00666431
JAG1 jagged 1 0.00665045
CENPT centromere protein T 0.00662153
NFIB nuclear factor I/B 0.00661154
DGKZ diacylglycerol kinase, zeta 0.00660903
KLK3 kallikrein-related peptidase 3 0.00659615
SOCS1 suppressor of cytokine signaling 1 0.00659226
ITGAV integrin, alpha V 0.00658002
EML3 echinoderm microtubule associated protein like 3 0.0065745
LMO3 LIM domain only 3 (rhombotin-like 2) 0.00656908
ESYT1 extended synaptotagmin-like protein 1 0.00656615
TES testin LIM domain protein 0.00656566
LIMCH1 LIM and calponin homology domains 1 0.00654528
CXCL9 chemokine (C-X-C motif) ligand 9 0.00654207
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 0.00654061
RBM26 RNA binding motif protein 26 0.00652968
MAGED1 melanoma antigen family D1 0.00649892
KANK1 KN motif and ankyrin repeat domains 1 0.00649018
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 0.00647402
GNG11 guanine nucleotide binding protein (G protein), gamma 11 0.00645801
COL10A1 collagen, type X, alpha 1 0.00643694
PRUNE2 prune homolog 2 (Drosophila) 0.00642784
TGFBI transforming growth factor, beta-induced, 68kDa 0.00641109
PDE10A phosphodiesterase 10A 0.00640318
GDF15 growth differentiation factor 15 0.00638887
SFTPB surfactant protein B 0.00636982
ACADVL acyl-CoA dehydrogenase, very long chain 0.00636621
DYNLL1 dynein, light chain, LC8-type 1 0.00635943
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 0.00632923
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 0.0063245
LAMA5 laminin, alpha 5 0.00631883
SYNE1 spectrin repeat containing, nuclear envelope 1 0.00631024
STAG3 stromal antigen 3 0.00630609
IPO13 importin 13 0.00627954
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.00626906
PERP PERP, TP53 apoptosis effector 0.00625457
SPHK1 sphingosine kinase 1 0.00624607
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 0.00623749
RPS4Y1 ribosomal protein S4, Y-linked 1 0.00623703
GGTLC1 gamma-glutamyltransferase light chain 1 0.00621915
PNISR PNN-interacting serine/arginine-rich protein 0.00621735
SLCO3A1 solute carrier organic anion transporter family, member 3A1 0.00621095
HSPA1A heat shock 70kDa protein 1A 0.00620192
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.00619781
HOMER3 homer scaffolding protein 3 0.00619509
TSPYL5 TSPY-like 5 0.00618026
OFD1 oral-facial-digital syndrome 1 0.0061689
TSPAN4 tetraspanin 4 0.00615603
SGK1 serum/glucocorticoid regulated kinase 1 0.00615471
TP63 tumor protein p63 0.00615241
COMP cartilage oligomeric matrix protein 0.00615108
PILRB paired immunoglobin-like type 2 receptor beta 0.00614922
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.0061472
NOTCH2NL notch 2 N-terminal like 0.0061445
AEBP1 AE binding protein 1 0.00614159
FOLH1B folate hydrolase 1B 0.00613355
CORO1B coronin, actin binding protein, 1B 0.00612737
NBL1 neuroblastoma 1, DAN family BMP antagonist 0.00611902
LDOC1 leucine zipper, down-regulated in cancer 1 0.00611674
WDR13 WD repeat domain 13 0.00611503
FN1 fibronectin 1 0.00611422
QSOX1 quiescin Q6 sulfhydryl oxidase 1 0.00611119
TUFT1 tuftelin 1 0.00609086
LTBP2 latent transforming growth factor beta binding protein 2 0.00608669
RGS16 regulator of G-protein signaling 16 0.00608189
SIDT2 SID1 transmembrane family, member 2 0.0060792
NPY neuropeptide Y 0.00607646
RANGAP1 Ran GTPase activating protein 1 0.00602873
PLXND1 plexin D1 0.0060058
PLAAT3 phospholipase A and acyltransferase 3 0.00598171
AP1G2 adaptor-related protein complex 1, gamma 2 subunit 0.00597768
FAM53B family with sequence similarity 53, member B 0.00597061
NUPR1 nuclear protein, transcriptional regulator, 1 0.00596505
ATG4B autophagy related 4B, cysteine peptidase 0.00595817
PLSCR3 phospholipid scramblase 3 0.00595571
DVL1 dishevelled segment polarity protein 1 0.00594785
CCN3 cellular communication network factor 3 0.00593233
PARP8 poly (ADP-ribose) polymerase family, member 8 0.00592909
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.00592751
EFHD2 EF-hand domain family, member D2 0.0059265
MARCKSL1 MARCKS-like 1 0.00591699
AGR2 anterior gradient 2 0.00591286
STXBP2 syntaxin binding protein 2 0.00590084
TMC6 transmembrane channel-like 6 0.00589197
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 0.00587581
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 0.00587058
CLDN1 claudin 1 0.00586972
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 0.00586266
MAOA monoamine oxidase A 0.00586122
SLC4A2 solute carrier family 4 (anion exchanger), member 2 0.00585832
GOLGA8H golgin A8 family, member H 0.00584784
MTCL1 microtubule crosslinking factor 1 0.00580688
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 0.00579679
CSPG4 chondroitin sulfate proteoglycan 4 0.00579215
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.00579151
ADCY1 adenylate cyclase 1 (brain) 0.00577734
RGL2 ral guanine nucleotide dissociation stimulator-like 2 0.0057629
NSUN5 NOP2/Sun domain family, member 5 0.00576044
UXT ubiquitously-expressed, prefoldin-like chaperone 0.00575862
TARP TCR gamma alternate reading frame protein 0.00575161
LONP1 lon peptidase 1, mitochondrial 0.00574133
MYO6 myosin VI 0.00572028
GZMK granzyme K (granzyme 3; tryptase II) 0.00571735
TGFB1I1 transforming growth factor beta 1 induced transcript 1 0.00571277
SFI1 Sfi1 homolog, spindle assembly associated (yeast) 0.00571224
LUM lumican 0.0056991
CAPN2 calpain 2, (m/II) large subunit 0.00569825
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 0.00568345
ZMIZ1 zinc finger, MIZ-type containing 1 0.00567657
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 0.00567025
ZBTB20 zinc finger and BTB domain containing 20 0.00566828
PDLIM5 PDZ and LIM domain 5 0.0056664
HCRT hypocretin (orexin) neuropeptide precursor 0.00565314
SLC38A1 solute carrier family 38, member 1 0.00565075
BCHE butyrylcholinesterase 0.00565028
SLCO1B3 solute carrier organic anion transporter family, member 1B3 0.00564478
LCAT lecithin-cholesterol acyltransferase 0.0056409
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase 0.00563881
PLCB4 phospholipase C, beta 4 0.00563751
PAN2 PAN2 poly(A) specific ribonuclease subunit 0.00563153
GLS glutaminase 0.00563077
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 0.00562439
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.00561393
NUMA1 nuclear mitotic apparatus protein 1 0.00560319
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 0.00560196

decreased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 -0.0266043
DEFB1 defensin, beta 1 -0.0156306
SEPP1 selenoprotein P, plasma, 1 -0.0146173
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -0.0142479
BEX1 brain expressed, X-linked 1 -0.014152
MAL mal, T-cell differentiation protein -0.0139372
DOK5 docking protein 5 -0.0122369
SPON1 spondin 1, extracellular matrix protein -0.0119585
SST somatostatin -0.0115985
AK4 adenylate kinase 4 -0.0114331
CA2 carbonic anhydrase II -0.0113007
CXCL12 chemokine (C-X-C motif) ligand 12 -0.0111311
EXOC5 exocyst complex component 5 -0.0109309
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 -0.0107456
NREP neuronal regeneration related protein -0.0105799
AZIN1 antizyme inhibitor 1 -0.0103141
FABP5 fatty acid binding protein 5 (psoriasis-associated) -0.0102434
AKR1C3 aldo-keto reductase family 1, member C3 -0.0102392
S100A7 S100 calcium binding protein A7 -0.010198
CRABP2 cellular retinoic acid binding protein 2 -0.0101797
S100A9 S100 calcium binding protein A9 -0.0101689
PEG3 paternally expressed 3 -0.00997645
F2RL1 coagulation factor II (thrombin) receptor-like 1 -0.00988163
ITM2A integral membrane protein 2A -0.00985887
SCNN1A sodium channel, non voltage gated 1 alpha subunit -0.00977921
PITX3 paired-like homeodomain 3 -0.00965737
CD200 CD200 molecule -0.00959657
YIPF5 Yip1 domain family, member 5 -0.00956694
MAP2K6 mitogen-activated protein kinase kinase 6 -0.00949626
HIGD1A HIG1 hypoxia inducible domain family, member 1A -0.00926186
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00921232
PEX2 peroxisomal biogenesis factor 2 -0.00914514
OLFML3 olfactomedin-like 3 -0.00900174
BMP4 bone morphogenetic protein 4 -0.00885706
GLUL glutamate-ammonia ligase -0.00881454
PI3 peptidase inhibitor 3, skin-derived -0.00876403
SLPI secretory leukocyte peptidase inhibitor -0.00871421
ARID4A AT rich interactive domain 4A (RBP1-like) -0.00866148
BCAT1 branched chain amino-acid transaminase 1, cytosolic -0.00860924
TANK TRAF family member-associated NFKB activator -0.00857783
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa -0.00854511
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -0.00853906
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -0.00853087
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -0.00849724
AGPS alkylglycerone phosphate synthase -0.00847401
TSPAN7 tetraspanin 7 -0.00847376
SELL selectin L -0.00846809
MECOM MDS1 and EVI1 complex locus -0.00844385
CGRRF1 cell growth regulator with ring finger domain 1 -0.00842383
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) -0.00841874
KLK8 kallikrein-related peptidase 8 -0.00830211
CPVL carboxypeptidase, vitellogenic-like -0.00828323
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -0.00825125
HILPDA hypoxia inducible lipid droplet-associated -0.00825018
C5ORF30 chromosome 5 open reading frame 30 -0.00819015
PLBD1 phospholipase B domain containing 1 -0.00818052
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -0.00816543
SCAMP1 secretory carrier membrane protein 1 -0.00811494
AP1S2 adaptor-related protein complex 1, sigma 2 subunit -0.00810936
PELI2 pellino E3 ubiquitin protein ligase family member 2 -0.00808888
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -0.00807946
COMMD10 COMM domain containing 10 -0.00806056
KLK6 kallikrein-related peptidase 6 -0.00804562
IL6ST interleukin 6 signal transducer -0.00799468
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00795374
HACD3 3-hydroxyacyl-CoA dehydratase 3 -0.0079163
BEX4 brain expressed, X-linked 4 -0.00789734
AOC1 amine oxidase, copper containing 1 -0.00786996
CLDN10 claudin 10 -0.00786119
SKP1 S-phase kinase-associated protein 1 -0.00785375
COX7B cytochrome c oxidase subunit VIIb -0.00781257
KCTD20 potassium channel tetramerization domain containing 20 -0.0078027
KCTD12 potassium channel tetramerization domain containing 12 -0.00777925
TXN thioredoxin -0.00777131
FAM198B family with sequence similarity 198, member B -0.0077645
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -0.00775233
FCGBP Fc fragment of IgG binding protein -0.0077345
SELENOT selenoprotein T -0.00772464
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -0.00771456
GCA grancalcin, EF-hand calcium binding protein -0.0077052
GPM6B glycoprotein M6B -0.00769942
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00769748
FAR2 fatty acyl CoA reductase 2 -0.007678
HIST1H2AC histone cluster 1, H2ac -0.00765753
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -0.00764133
CFI complement factor I -0.00762539
CA12 carbonic anhydrase XII -0.00760707
GPC3 glypican 3 -0.00759273
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 -0.00755348
EAPP E2F-associated phosphoprotein -0.00751131
CEL carboxyl ester lipase -0.00750546
STMN2 stathmin 2 -0.00749587
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.00749501
ACOX2 acyl-CoA oxidase 2, branched chain -0.00747226
PLIN3 perilipin 3 -0.00745775
ARMCX2 armadillo repeat containing, X-linked 2 -0.00745598
CDC42 cell division cycle 42 -0.00744787
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.0074
OXTR oxytocin receptor -0.00738641
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -0.00736768
DPYD dihydropyrimidine dehydrogenase -0.00735445
PTBP3 polypyrimidine tract binding protein 3 -0.00734997
KLK7 kallikrein-related peptidase 7 -0.00734537
TMOD3 tropomodulin 3 (ubiquitous) -0.00734228
GNA13 guanine nucleotide binding protein (G protein), alpha 13 -0.00727623
CLCA4 chloride channel accessory 4 -0.00726841
WFDC2 WAP four-disulfide core domain 2 -0.00726268
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial -0.00724888
MUC16 mucin 16, cell surface associated -0.00724204
LSM1 LSM1, U6 small nuclear RNA associated -0.00720301
UBE2E3 ubiquitin-conjugating enzyme E2E 3 -0.00719583
DHRS9 dehydrogenase/reductase (SDR family) member 9 -0.00717105
ELL2 elongation factor, RNA polymerase II, 2 -0.00713205
ANPEP alanyl (membrane) aminopeptidase -0.00712754
TSPAN31 tetraspanin 31 -0.00712469
CLIC5 chloride intracellular channel 5 -0.00711698
TLR4 toll-like receptor 4 -0.00705174
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.00704755
TSPAN3 tetraspanin 3 -0.00703906
NR1D2 nuclear receptor subfamily 1, group D, member 2 -0.00703373
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 -0.00701335
SGPP1 sphingosine-1-phosphate phosphatase 1 -0.00700891
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -0.00700495
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00698969
PADI2 peptidyl arginine deiminase, type II -0.00697687
EIF5 eukaryotic translation initiation factor 5 -0.00696386
BTG3 BTG family, member 3 -0.0069468
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) -0.00690806
ICAM3 intercellular adhesion molecule 3 -0.00688932
MED6 mediator complex subunit 6 -0.00686418
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -0.00685981
ESR1 estrogen receptor 1 -0.00685846
TNIP1 TNFAIP3 interacting protein 1 -0.00684915
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -0.00684419
LRRC17 leucine rich repeat containing 17 -0.00683785
GHITM growth hormone inducible transmembrane protein -0.00681678
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 -0.00680512
NRN1 neuritin 1 -0.0067956
FGL2 fibrinogen-like 2 -0.0067808
LDB2 LIM domain binding 2 -0.00676582
GAB2 GRB2-associated binding protein 2 -0.00674315
AK2 adenylate kinase 2 -0.00671504
MRPL22 mitochondrial ribosomal protein L22 -0.00671184
MAPK14 mitogen-activated protein kinase 14 -0.00670101
TMEM47 transmembrane protein 47 -0.00668264
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha -0.00668021
LASP1 LIM and SH3 protein 1 -0.00668002
PJA2 praja ring finger 2, E3 ubiquitin protein ligase -0.00666246
CHMP2B charged multivesicular body protein 2B -0.00664793
UQCRC2 ubiquinol-cytochrome c reductase core protein II -0.00660966
EMX2 empty spiracles homeobox 2 -0.0066003
EMP1 epithelial membrane protein 1 -0.00658561
BAMBI BMP and activin membrane-bound inhibitor -0.00657848
OLFM1 olfactomedin 1 -0.00657442
HIPK3 homeodomain interacting protein kinase 3 -0.00656886
TFDP1 transcription factor Dp-1 -0.00655399
DLAT dihydrolipoamide S-acetyltransferase -0.0065339
CES1 carboxylesterase 1 -0.00651584
KLK10 kallikrein-related peptidase 10 -0.00649223
MEN1 multiple endocrine neoplasia I -0.00648118
JPT1 Jupiter microtubule associated homolog 1 -0.00647862
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) -0.00647579
MAGT1 magnesium transporter 1 -0.00646989
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -0.00646588
S100A14 S100 calcium binding protein A14 -0.00646516
XPO7 exportin 7 -0.00645967
MOCS2 molybdenum cofactor synthesis 2 -0.00645705
DCTN4 dynactin 4 (p62) -0.00644214
ATP5F1C ATP synthase F1 subunit gamma -0.00643945
CLEC2B C-type lectin domain family 2, member B -0.00643841
S1PR1 sphingosine-1-phosphate receptor 1 -0.00642983
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.00642976
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) -0.00640217
MARCKS myristoylated alanine-rich protein kinase C substrate -0.00640023
CHEK1 checkpoint kinase 1 -0.00637068
NOLC1 nucleolar and coiled-body phosphoprotein 1 -0.00636631
PRKCQ protein kinase C, theta -0.00635406
GPR183 G protein-coupled receptor 183 -0.00635395
TPBG trophoblast glycoprotein -0.00633319
TMEM176B transmembrane protein 176B -0.00632576
RPA3 replication protein A3, 14kDa -0.00631637
DAZAP2 DAZ associated protein 2 -0.00630507
MAN1A1 mannosidase, alpha, class 1A, member 1 -0.00626351
DNTT DNA nucleotidylexotransferase -0.00625979
CRK v-crk avian sarcoma virus CT10 oncogene homolog -0.00623758
SLC39A9 solute carrier family 39, member 9 -0.00622996
WDR61 WD repeat domain 61 -0.0062291
FKBP5 FK506 binding protein 5 -0.00620558
CLU clusterin -0.00619686
ARL3 ADP-ribosylation factor-like 3 -0.00618594
CRYZ crystallin, zeta (quinone reductase) -0.0061835
SRSF1 serine/arginine-rich splicing factor 1 -0.00618023
WDR48 WD repeat domain 48 -0.00614707
RPL26L1 ribosomal protein L26-like 1 -0.00613201
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.00612937
TXNIP thioredoxin interacting protein -0.00611943
LYPLA1 lysophospholipase I -0.00610964
RHOH ras homolog family member H -0.00608645
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 -0.00608586
SPINK5 serine peptidase inhibitor, Kazal type 5 -0.00608162
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.00608139
CD59 CD59 molecule, complement regulatory protein -0.00607766
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.00607408
STEAP1 six transmembrane epithelial antigen of the prostate 1 -0.00607295
TSPAN6 tetraspanin 6 -0.00605444
SIRT3 sirtuin 3 -0.00604428
CTSS cathepsin S -0.00604068
DCK deoxycytidine kinase -0.00602953
RBBP4 retinoblastoma binding protein 4 -0.00602655
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.00602035
TTC1 tetratricopeptide repeat domain 1 -0.00599753
TUBB2A tubulin, beta 2A class IIa -0.00599423
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -0.00599169
CHODL chondrolectin -0.00598651
TMEM176A transmembrane protein 176A -0.0059779
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 -0.00597492
RPP14 ribonuclease P/MRP 14kDa subunit -0.00596574
RIMBP2 RIMS binding protein 2 -0.00596455
TSLIG2 tRNA splicing ligase complex subunit 2 -0.00594105
GEMIN2 gem (nuclear organelle) associated protein 2 -0.00593925
MRPL18 mitochondrial ribosomal protein L18 -0.00593672
CD86 CD86 molecule -0.00593055
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 -0.00592574
CCL14 chemokine (C-C motif) ligand 14 -0.00591995
MARCHF7 membrane associated ring-CH-type finger 7 -0.00591864
REEP5 receptor accessory protein 5 -0.00590327
POT1 protection of telomeres 1 -0.00589777
RCAN1 regulator of calcineurin 1 -0.00588947
KPNA4 karyopherin alpha 4 (importin alpha 3) -0.00588566
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.00588471
HSPA12A heat shock 70kDa protein 12A -0.00588145
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 -0.00587872
HSBP1 heat shock factor binding protein 1 -0.00587423
CHMP1B charged multivesicular body protein 1B -0.00586642
IRF4 interferon regulatory factor 4 -0.00586492
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 -0.00585539
NAV3 neuron navigator 3 -0.00585149
CCDC6 coiled-coil domain containing 6 -0.00584784
PDK1 pyruvate dehydrogenase kinase, isozyme 1 -0.00582859
RBX1 ring-box 1, E3 ubiquitin protein ligase -0.00577881
TPM4 tropomyosin 4 -0.00577222
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -0.00576218
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.00576215
FZD6 frizzled class receptor 6 -0.00576009
SOX17 SRY (sex determining region Y)-box 17 -0.0057552
COX5B cytochrome c oxidase subunit Vb -0.00575188
FLI1 Fli-1 proto-oncogene, ETS transcription factor -0.00574971
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -0.0057474
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 -0.00574283