NOS1AP Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description nitric oxide synthase 1 (neuronal) adaptor protein|This gene encodes a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS). This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 9722)
External Link http://www.ncbi.nlm.nih.gov/gene/9722
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10 interacting proteins for NOS1AP from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
APP amyloid beta (A4) precursor protein
LRP1 low density lipoprotein receptor-related protein 1
LRP2 low density lipoprotein receptor-related protein 2
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
NOS1 nitric oxide synthase 1 (neuronal)
PTPRN protein tyrosine phosphatase, receptor type, N
RASD1 RAS, dexamethasone-induced 1
SYN1 synapsin I
SYN2 synapsin II
SYN3 synapsin III