NOS2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description nitric oxide synthase 2, inducible|Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4843)
External Link https://ncbi.nlm.nih.gov/gene/4843
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Genes

498 genes differentially expressed following the NOS2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 0.0247918
SPRED2 sprouty-related, EVH1 domain containing 2 0.0138041
KYNU kynureninase 0.0130265
ETFB electron-transfer-flavoprotein, beta polypeptide 0.0123247
GPX3 glutathione peroxidase 3 0.011798
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.0110311
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 0.0107206
TFF1 trefoil factor 1 0.0105932
STC1 stanniocalcin 1 0.0105563
IFI16 interferon, gamma-inducible protein 16 0.0104716
MAL mal, T-cell differentiation protein 0.0103281
BIRC3 baculoviral IAP repeat containing 3 0.0100659
ALDOB aldolase B, fructose-bisphosphate 0.00976668
PDZK1IP1 PDZK1 interacting protein 1 0.00973305
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.00973277
GALC galactosylceramidase 0.00963492
AOC1 amine oxidase, copper containing 1 0.00950943
ZFP36L2 ZFP36 ring finger protein-like 2 0.00941432
TM4SF1 transmembrane 4 L six family member 1 0.00921671
ANXA1 annexin A1 0.0092035
PRKCA protein kinase C, alpha 0.00914646
CXCL12 chemokine (C-X-C motif) ligand 12 0.00904817
DEFB1 defensin, beta 1 0.0090042
PTHLH parathyroid hormone-like hormone 0.00896368
WT1 Wilms tumor 1 0.00887862
AK4 adenylate kinase 4 0.00878187
MDK midkine (neurite growth-promoting factor 2) 0.00872335
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.00869438
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00864813
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.00864757
VNN1 vanin 1 0.00862421
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 0.00854785
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.00845246
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.00845236
SEPP1 selenoprotein P, plasma, 1 0.00843611
ETHE1 ethylmalonic encephalopathy 1 0.00841411
ADM adrenomedullin 0.00821964
SFRP1 secreted frizzled-related protein 1 0.008187
MMD monocyte to macrophage differentiation-associated 0.00815918
FCGBP Fc fragment of IgG binding protein 0.00808285
BEX4 brain expressed, X-linked 4 0.00807414
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 0.00799465
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 0.00792291
FABP6 fatty acid binding protein 6, ileal 0.00791701
DEPTOR DEP domain containing MTOR-interacting protein 0.00786947
TUBB2A tubulin, beta 2A class IIa 0.00772562
CALB1 calbindin 1, 28kDa 0.00770927
CD1E CD1e molecule 0.00767206
IL15 interleukin 15 0.00754364
SELENBP1 selenium binding protein 1 0.00753633
MAN1C1 mannosidase, alpha, class 1C, member 1 0.00751272
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.00747098
ESD esterase D 0.00739582
TFPI2 tissue factor pathway inhibitor 2 0.00739519
AREG amphiregulin 0.00737399
YPEL5 yippee-like 5 (Drosophila) 0.00735786
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.00732996
CXCL5 chemokine (C-X-C motif) ligand 5 0.00732282
MT1X metallothionein 1X 0.00731274
CLTB clathrin, light chain B 0.00728807
CNN1 calponin 1, basic, smooth muscle 0.00728599
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 0.00724026
ZMAT3 zinc finger, matrin-type 3 0.00723197
CRYBG1 crystallin beta-gamma domain containing 1 0.00722281
RCAN1 regulator of calcineurin 1 0.00721664
FOLR1 folate receptor 1 (adult) 0.00712238
TARBP1 TAR (HIV-1) RNA binding protein 1 0.00708497
SLC22A18 solute carrier family 22, member 18 0.00705714
DHRS9 dehydrogenase/reductase (SDR family) member 9 0.00700953
ADD3 adducin 3 (gamma) 0.00700883
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00697136
CLIC2 chloride intracellular channel 2 0.00696962
CD59 CD59 molecule, complement regulatory protein 0.00695536
MVP major vault protein 0.00694387
CRYAB crystallin, alpha B 0.00690771
UFC1 ubiquitin-fold modifier conjugating enzyme 1 0.00685266
FGF13 fibroblast growth factor 13 0.00682571
ASS1 argininosuccinate synthase 1 0.00677444
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.00674374
TMX4 thioredoxin-related transmembrane protein 4 0.00672453
DAXX death-domain associated protein 0.00670522
LGALS4 lectin, galactoside-binding, soluble, 4 0.00669525
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 0.00666673
GRB7 growth factor receptor-bound protein 7 0.00663168
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.00661825
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.00659847
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.00659103
TGFBI transforming growth factor, beta-induced, 68kDa 0.00655625
TP53I3 tumor protein p53 inducible protein 3 0.00655568
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.00649459
PHLDA2 pleckstrin homology-like domain, family A, member 2 0.0064917
FABP1 fatty acid binding protein 1, liver 0.00648766
TUBB2B tubulin, beta 2B class IIb 0.00647419
C6ORF48 chromosome 6 open reading frame 48 0.00647314
MRPS16 mitochondrial ribosomal protein S16 0.00646002
HEPH hephaestin 0.00644123
RSL1D1 ribosomal L1 domain containing 1 0.00643545
CD3D CD3d molecule, delta (CD3-TCR complex) 0.00641787
RHOC ras homolog family member C 0.00641199
LY75 lymphocyte antigen 75 0.0064088
BLVRB biliverdin reductase B 0.00640069
MLF1 myeloid leukemia factor 1 0.00639692
CHGB chromogranin B 0.00639595
UGP2 UDP-glucose pyrophosphorylase 2 0.00638149
CCL20 chemokine (C-C motif) ligand 20 0.00636529
REG1A regenerating islet-derived 1 alpha 0.00636322
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 0.00635978
CD1B CD1b molecule 0.0063384
ANPEP alanyl (membrane) aminopeptidase 0.00633556
FAR2 fatty acyl CoA reductase 2 0.00629791
GLIPR1 GLI pathogenesis-related 1 0.00628445
S100A9 S100 calcium binding protein A9 0.00628383
KRT20 keratin 20, type I 0.00622801
LGALS13 lectin, galactoside-binding, soluble, 13 0.00622679
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.00622259
CETN2 centrin, EF-hand protein, 2 0.00621277
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 0.00620981
STK17A serine/threonine kinase 17a 0.00618109
ACOX2 acyl-CoA oxidase 2, branched chain 0.00617568
S100A8 S100 calcium binding protein A8 0.00617442
CYBRD1 cytochrome b reductase 1 0.00616028
RTN1 reticulon 1 0.00613983
RTCA RNA 3'-terminal phosphate cyclase 0.00611572
HSPA8 heat shock 70kDa protein 8 0.00609979
MXI1 MAX interactor 1, dimerization protein 0.00609333
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.00607069
RAB21 RAB21, member RAS oncogene family 0.00603747
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.0060337
CD86 CD86 molecule 0.00602193
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.00600137
PSAP prosaposin 0.0059973
KRT81 keratin 81, type II 0.00598867
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.00598546
ALB albumin 0.0059816
TPD52L1 tumor protein D52-like 1 0.00596694
HCRT hypocretin (orexin) neuropeptide precursor 0.00596575
LCN2 lipocalin 2 0.00595352
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00593835
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.00592254
ZNF185 zinc finger protein 185 (LIM domain) 0.00590531
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.00590505
HOXB7 homeobox B7 0.00590246
ITGAV integrin, alpha V 0.00589806
DDIT3 DNA-damage-inducible transcript 3 0.00589076
PRR13 proline rich 13 0.00588979
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.00587597
HDDC2 HD domain containing 2 0.00586662
AFP alpha-fetoprotein 0.00586445
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 0.00586262
IL2RG interleukin 2 receptor, gamma 0.00585702
HIST1H2AC histone cluster 1, H2ac 0.00584832
LAMP3 lysosomal-associated membrane protein 3 0.00583652
TM4SF20 transmembrane 4 L six family member 20 0.00582907
SPATA2L spermatogenesis associated 2-like 0.00579004
NMD3 NMD3 ribosome export adaptor 0.00578874
STON1 stonin 1 0.00578745
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.00578279
GLDC glycine dehydrogenase (decarboxylating) 0.0057647
GDI2 GDP dissociation inhibitor 2 0.0057597
MCTS1 malignant T cell amplified sequence 1 0.005753
PFKP phosphofructokinase, platelet 0.00575137
TSPAN8 tetraspanin 8 0.00573872
GPR137B G protein-coupled receptor 137B 0.00573819
KLK8 kallikrein-related peptidase 8 0.00573517
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 0.00571681
MGLL monoglyceride lipase 0.00571517
PDE8B phosphodiesterase 8B 0.00569584
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.00567507
PTEN phosphatase and tensin homolog 0.00566335
INAVA innate immunity activator 0.00563637
CCDC6 coiled-coil domain containing 6 0.0056332
ADGRG2 adhesion G protein-coupled receptor G2 0.0055931
GYPC glycophorin C (Gerbich blood group) 0.00558608
ACTG2 actin, gamma 2, smooth muscle, enteric 0.00558516
CP ceruloplasmin (ferroxidase) 0.00556483
APOB apolipoprotein B 0.00555595
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00554515
CHRDL1 chordin-like 1 0.00554511
MME membrane metallo-endopeptidase 0.00552956
MBNL1 muscleblind-like splicing regulator 1 0.00550774
ISG20 interferon stimulated exonuclease gene 20kDa 0.00549096
PCCB propionyl CoA carboxylase, beta polypeptide 0.00548699
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.00548112
STOM stomatin 0.00547016
CHIC2 cysteine-rich hydrophobic domain 2 0.00547004
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 0.00544807
UST uronyl-2-sulfotransferase 0.00544386
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.00543074
DHRS11 dehydrogenase/reductase (SDR family) member 11 0.00541808
NT5E 5'-nucleotidase, ecto (CD73) 0.00541598
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 0.00540833
SH3TC1 SH3 domain and tetratricopeptide repeats 1 0.00540136
IL13RA2 interleukin 13 receptor, alpha 2 0.00535819
GBP2 guanylate binding protein 2, interferon-inducible 0.00534544
FOXG1 forkhead box G1 0.00533921
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.00533622
ARL4A ADP-ribosylation factor-like 4A 0.00533292
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.00529498
NEBL nebulette 0.00529057
APOA1 apolipoprotein A-I 0.00527799
DEFA5 defensin, alpha 5, Paneth cell-specific 0.0052599
HOXC6 homeobox C6 0.005256
LINC00623 long intergenic non-protein coding RNA 623 0.00525345
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.00525277
LGALS9 lectin, galactoside-binding, soluble, 9 0.00524966
FTH1 ferritin, heavy polypeptide 1 0.00524548
HSPB1 heat shock 27kDa protein 1 0.00524153
RALB v-ral simian leukemia viral oncogene homolog B 0.00523536
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 0.00523035
RNASET2 ribonuclease T2 0.00522249
IGBP1 immunoglobulin (CD79A) binding protein 1 0.00520567
TRAF5 TNF receptor-associated factor 5 0.00519168
DNTT DNA nucleotidylexotransferase 0.00518855
DUOX2 dual oxidase 2 0.00517826
YBX3 Y box binding protein 3 0.00517296
ACVR1B activin A receptor, type IB 0.00515726
HHLA3 HERV-H LTR-associating 3 0.0051535
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 0.0051494
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 0.00514539
ZNF318 zinc finger protein 318 0.00514086
OGA O-GlcNAcase 0.00513396
FTSJ3 FtsJ homolog 3 (E. coli) 0.00512833
ADA adenosine deaminase 0.0051277
MYB v-myb avian myeloblastosis viral oncogene homolog 0.00512165
PLP1 proteolipid protein 1 0.00511376
LETMD1 LETM1 domain containing 1 0.00511066
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.00510164
REG1B regenerating islet-derived 1 beta 0.00509543
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 0.00507858
DLG5 discs, large homolog 5 (Drosophila) 0.00507172
RHOF ras homolog family member F (in filopodia) 0.00506774
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 0.00506375
IGFBP5 insulin-like growth factor binding protein 5 0.00506371
SF3A1 splicing factor 3a, subunit 1, 120kDa 0.00506224
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.00505949
ZNF277 zinc finger protein 277 0.00505666
CHD1 chromodomain helicase DNA binding protein 1 0.0050322
CD96 CD96 molecule 0.00502343
HOXB2 homeobox B2 0.00501297
CTSC cathepsin C 0.00501092
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.00500224
RRAD Ras-related associated with diabetes 0.00500007
HNMT histamine N-methyltransferase 0.0049976
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.00499668
MFAP5 microfibrillar associated protein 5 0.00498955
C10ORF10 chromosome 10 open reading frame 10 0.00496148
DHRS7 dehydrogenase/reductase (SDR family) member 7 0.00496011
CFI complement factor I 0.00494658
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.00494544

decreased expression

Symbol Name Standardized Value
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0220306
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -0.0217184
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.0127467
TIMP3 TIMP metallopeptidase inhibitor 3 -0.0121015
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.0111252
S100A2 S100 calcium binding protein A2 -0.0105632
MNAT1 MNAT CDK-activating kinase assembly factor 1 -0.0098626
ASPN asporin -0.00947865
LRRC17 leucine rich repeat containing 17 -0.00938689
FASN fatty acid synthase -0.00932921
KRT5 keratin 5, type II -0.00920264
COMP cartilage oligomeric matrix protein -0.00916617
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.00913105
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.00907027
RAPSN receptor-associated protein of the synapse -0.00870641
CCND1 cyclin D1 -0.00868579
TACSTD2 tumor-associated calcium signal transducer 2 -0.00863622
CCNA2 cyclin A2 -0.00829558
SFRP4 secreted frizzled-related protein 4 -0.00825149
KRT17 keratin 17, type I -0.00810581
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -0.00786982
LRRC15 leucine rich repeat containing 15 -0.0078168
ENO3 enolase 3 (beta, muscle) -0.00777467
DSP desmoplakin -0.00773413
DYNLL1 dynein, light chain, LC8-type 1 -0.0076806
KIF5B kinesin family member 5B -0.00765205
POSTN periostin, osteoblast specific factor -0.00759805
TNNI2 troponin I type 2 (skeletal, fast) -0.00751111
MFAP2 microfibrillar-associated protein 2 -0.00731866
PKM pyruvate kinase, muscle -0.00726414
H1-0 H1.0 linker histone -0.00721706
ELN elastin -0.00718845
PTPRD protein tyrosine phosphatase, receptor type, D -0.00708851
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 -0.00707326
SIX1 SIX homeobox 1 -0.00699597
PILRB paired immunoglobin-like type 2 receptor beta -0.00698644
PLD3 phospholipase D family, member 3 -0.00694658
TPSAB1 tryptase alpha/beta 1 -0.00694447
MMP1 matrix metallopeptidase 1 -0.00694107
CXCL9 chemokine (C-X-C motif) ligand 9 -0.00691578
CIT citron rho-interacting serine/threonine kinase -0.00691259
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -0.00687282
KRAS Kirsten rat sarcoma viral oncogene homolog -0.00683789
FSTL1 follistatin-like 1 -0.00682724
COL3A1 collagen, type III, alpha 1 -0.00682547
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor -0.00682271
PCLAF PCNA clamp associated factor -0.00682228
LUM lumican -0.00681592
NBPF10 neuroblastoma breakpoint family, member 10 -0.00677513
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -0.00675025
ABHD17A abhydrolase domain containing 17A -0.00674822
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 -0.00672784
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00668318
SLIT2 slit homolog 2 (Drosophila) -0.00666968
PDPK1 3-phosphoinositide dependent protein kinase 1 -0.00666866
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00664917
HELLS helicase, lymphoid-specific -0.00662432
MMP11 matrix metallopeptidase 11 -0.00660674
COL2A1 collagen, type II, alpha 1 -0.00655928
FUS FUS RNA binding protein -0.006543
MYBPC1 myosin binding protein C, slow type -0.00654098
WDR7 WD repeat domain 7 -0.00653925
TTN titin -0.00649892
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00648763
KLF2 Kruppel-like factor 2 -0.0064669
WSB1 WD repeat and SOCS box containing 1 -0.00645364
FN1 fibronectin 1 -0.00645149
FKBP11 FK506 binding protein 11, 19 kDa -0.00642915
COL16A1 collagen, type XVI, alpha 1 -0.00634437
MSX1 msh homeobox 1 -0.00631665
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.00631223
CKM creatine kinase, muscle -0.00628565
CCNL2 cyclin L2 -0.00628105
TMSB15A thymosin beta 15a -0.0062777
SFN stratifin -0.00626614
ABHD3 abhydrolase domain containing 3 -0.006246
INSIG1 insulin induced gene 1 -0.00618999
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -0.00616693
TNNI1 troponin I type 1 (skeletal, slow) -0.00616459
ZBTB20 zinc finger and BTB domain containing 20 -0.00614524
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -0.00612646
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 -0.00611249
PRDX2 peroxiredoxin 2 -0.00610392
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase -0.00609752
SIGLEC15 sialic acid binding Ig-like lectin 15 -0.00605389
RAD23B RAD23 homolog B (S. cerevisiae) -0.00602831
MYL1 myosin, light chain 1, alkali; skeletal, fast -0.00602145
MFSD10 major facilitator superfamily domain containing 10 -0.00602137
PRR11 proline rich 11 -0.00601768
RTN2 reticulon 2 -0.00600051
PSRC1 proline/serine-rich coiled-coil 1 -0.00599539
RGS16 regulator of G-protein signaling 16 -0.00597822
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -0.00596292
AURKB aurora kinase B -0.00594865
WASL Wiskott-Aldrich syndrome-like -0.00594463
SLC38A2 solute carrier family 38, member 2 -0.00588026
JCHAIN joining chain of multimeric IgA and IgM -0.00587874
CADM1 cell adhesion molecule 1 -0.00584736
NOTCH2NL notch 2 N-terminal like -0.00583628
CPA3 carboxypeptidase A3 (mast cell) -0.00582239
NPEPL1 aminopeptidase-like 1 -0.0058042
COL10A1 collagen, type X, alpha 1 -0.00579761
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -0.00575255
PDLIM5 PDZ and LIM domain 5 -0.00574259
CALR calreticulin -0.00574096
STK10 serine/threonine kinase 10 -0.00572328
PPL periplakin -0.00572015
SNX7 sorting nexin 7 -0.00571608
MBL2 mannose-binding lectin (protein C) 2, soluble -0.00570215
SIKE1 suppressor of IKBKE 1 -0.00570212
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -0.00570167
KRT23 keratin 23, type I -0.00568085
SMAD7 SMAD family member 7 -0.00567916
PGC progastricsin (pepsinogen C) -0.00566729
ALPK3 alpha-kinase 3 -0.00566117
GINS1 GINS complex subunit 1 (Psf1 homolog) -0.00562605
TAGLN transgelin -0.00561821
TYMS thymidylate synthetase -0.00560965
BGN biglycan -0.00560377
CRLF1 cytokine receptor-like factor 1 -0.00559832
MTCL1 microtubule crosslinking factor 1 -0.00557709
NPIPB3 nuclear pore complex interacting protein family, member B3 -0.00556547
MB myoglobin -0.00555385
TSPAN12 tetraspanin 12 -0.00553357
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.00550107
HMGB3 high mobility group box 3 -0.00547269
PRC1 protein regulator of cytokinesis 1 -0.00546543
SLC16A6 solute carrier family 16, member 6 -0.00545946
PPP1R10 protein phosphatase 1, regulatory subunit 10 -0.00545307
H2AZ1 H2A.Z variant histone 1 -0.00545295
SFTPD surfactant protein D -0.00542992
FBXO2 F-box protein 2 -0.00542912
TK1 thymidine kinase 1, soluble -0.00541525
LOXL2 lysyl oxidase-like 2 -0.00538892
TPD52 tumor protein D52 -0.00538632
CALCA calcitonin-related polypeptide alpha -0.00538459
CSK c-src tyrosine kinase -0.00535454
NXN nucleoredoxin -0.00534273
MCM2 minichromosome maintenance complex component 2 -0.00534147
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00532925
ZNF512B zinc finger protein 512B -0.00532643
FBXW12 F-box and WD repeat domain containing 12 -0.00530731
ZNF160 zinc finger protein 160 -0.00529881
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00529822
SCGN secretagogin, EF-hand calcium binding protein -0.00529578
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0052939
TNNT1 troponin T type 1 (skeletal, slow) -0.00529108
BCHE butyrylcholinesterase -0.005278
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle -0.00527784
SNAI2 snail family zinc finger 2 -0.00527182
KIF20A kinesin family member 20A -0.00526747
FOXM1 forkhead box M1 -0.00526677
LOXL1 lysyl oxidase-like 1 -0.0052239
TMEM41B transmembrane protein 41B -0.00522263
PDIA3 protein disulfide isomerase family A, member 3 -0.00522033
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.00521772
DACH1 dachshund family transcription factor 1 -0.00521057
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 -0.00520451
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) -0.00519532
ANKRD10 ankyrin repeat domain 10 -0.00518431
GNAS GNAS complex locus -0.00518118
NELFB negative elongation factor complex member B -0.00518117
CREB1 cAMP responsive element binding protein 1 -0.00515726
THAP12 THAP domain containing 12 -0.00514903
AMIGO2 adhesion molecule with Ig-like domain 2 -0.0051471
TMEM184B transmembrane protein 184B -0.00513604
SFTPA2 surfactant protein A2 -0.00512093
RHOB ras homolog family member B -0.00511672
CLUH clustered mitochondria (cluA/CLU1) homolog -0.00510754
SRRM2 serine/arginine repetitive matrix 2 -0.0050947
MECOM MDS1 and EVI1 complex locus -0.00508701
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -0.00508298
PLXNA2 plexin A2 -0.00503971
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor -0.00501425
THBS4 thrombospondin 4 -0.0050118
MMP9 matrix metallopeptidase 9 -0.00500112
BTBD3 BTB (POZ) domain containing 3 -0.00498041
TNNT3 troponin T type 3 (skeletal, fast) -0.00496037
DAPK1 death-associated protein kinase 1 -0.00495853
LMNB2 lamin B2 -0.00495411
ATAD3A ATPase family, AAA domain containing 3A -0.00495016
MCM4 minichromosome maintenance complex component 4 -0.00494617
NR4A1 nuclear receptor subfamily 4, group A, member 1 -0.00494158
COL5A2 collagen, type V, alpha 2 -0.00494031
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha -0.00493628
ZWINT ZW10 interacting kinetochore protein -0.00493257
PRKCZ protein kinase C, zeta -0.0049265
FABP4 fatty acid binding protein 4, adipocyte -0.0049259
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.00492051
TNK2 tyrosine kinase, non-receptor, 2 -0.00491505
PHACTR2 phosphatase and actin regulator 2 -0.00491424
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) -0.00490815
KIF18B kinesin family member 18B -0.00490808
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 -0.00490421
DUT deoxyuridine triphosphatase -0.00490161
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -0.00489739
ESRP2 epithelial splicing regulatory protein 2 -0.00489344
COL11A1 collagen, type XI, alpha 1 -0.00489019
CAPN15 calpain 15 -0.00488521
CPB1 carboxypeptidase B1 (tissue) -0.00488508
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial -0.00488472
UPK1A uroplakin 1A -0.00488237
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -0.00487566
PLXNB1 plexin B1 -0.00487303
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) -0.00486249
TFF3 trefoil factor 3 (intestinal) -0.00486065
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 -0.00485849
FOXC1 forkhead box C1 -0.00485783
MYBPC2 myosin binding protein C, fast type -0.00485655
CCND2 cyclin D2 -0.00485573
DCK deoxycytidine kinase -0.0048422
SCD5 stearoyl-CoA desaturase 5 -0.00484057
RUFY3 RUN and FYVE domain containing 3 -0.00483754
KLHL41 kelch-like family member 41 -0.00483136
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -0.00482733
TBX3 T-box 3 -0.00481649
FXYD6 FXYD domain containing ion transport regulator 6 -0.00481597
GLO1 glyoxalase I -0.00481536
PKP1 plakophilin 1 -0.00480906
CLEC7A C-type lectin domain family 7, member A -0.00479416
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) -0.00478595
TSPO translocator protein (18kDa) -0.00478089
KIF1A kinesin family member 1A -0.0047716
DPT dermatopontin -0.00476937
EXPH5 exophilin 5 -0.00476083
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 -0.00476019
CERS4 ceramide synthase 4 -0.00475208
PFAS phosphoribosylformylglycinamidine synthase -0.00474117
CRTAC1 cartilage acidic protein 1 -0.00473988
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha -0.0047327
CGA glycoprotein hormones, alpha polypeptide -0.00472424
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 -0.0047167
FRY furry homolog (Drosophila) -0.00471612
ANAPC2 anaphase promoting complex subunit 2 -0.00470879
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.00470851
AMOTL2 angiomotin like 2 -0.00470718
GLRX2 glutaredoxin 2 -0.00470531
CCN2 cellular communication network factor 2 -0.00469851
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.00468398
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -0.00467057
CD9 CD9 molecule -0.00466113
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -0.00464513
BPIFA1 BPI fold containing family A, member 1 -0.00464376
RCAN2 regulator of calcineurin 2 -0.00462943
NADK NAD kinase -0.00462523
CENPT centromere protein T -0.00462457
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 -0.00462072
ACTN4 actinin, alpha 4 -0.00461906
GNG10 guanine nucleotide binding protein (G protein), gamma 10 -0.00459872