NOS2 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description nitric oxide synthase 2, inducible|Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4843)
External Link http://www.ncbi.nlm.nih.gov/gene/4843
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Genes

166 interacting proteins for NOS2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ACTB actin, beta
ACTN4 actinin, alpha 4
ADRM1 adhesion regulating molecule 1
AGR2 anterior gradient 2
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ASPH aspartate beta-hydroxylase
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
BAG2 BCL2-associated athanogene 2
C1QBP complement component 1, q subcomponent binding protein
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CALU calumenin
CAV1 caveolin 1, caveolae protein, 22kDa
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CCT3 chaperonin containing TCP1, subunit 3 (gamma)
CCT4 chaperonin containing TCP1, subunit 4 (delta)
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)
CCT7 chaperonin containing TCP1, subunit 7 (eta)
CCT8 chaperonin containing TCP1, subunit 8 (theta)
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CLNS1A chloride channel, nucleotide-sensitive, 1A
COPRS coordinator of PRMT5, differentiation stimulator
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CUL5 cullin 5
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DICER1 dicer 1, ribonuclease type III
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
EMD emerin
FASN fatty acid synthase
FAT1 FAT atypical cadherin 1
FBXO45 F-box protein 45
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HACD3 3-hydroxyacyl-CoA dehydratase 3
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
HKDC1 hexokinase domain containing 1
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPF heterogeneous nuclear ribonucleoprotein F
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA2 heat shock 70kDa protein 2
HSPA4 heat shock 70kDa protein 4
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPB1 heat shock 27kDa protein 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPH1 heat shock 105kDa/110kDa protein 1
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
ICAM1 intercellular adhesion molecule 1
IL12A interleukin 12A
IL12B interleukin 12B
IL12RB1 interleukin 12 receptor, beta 1
IL12RB2 interleukin 12 receptor, beta 2
JAK2 Janus kinase 2
KPNB1 karyopherin (importin) beta 1
KRT18 keratin 18, type I
KRT8 keratin 8, type II
KRT81 keratin 81, type II
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MAPK3 mitogen-activated protein kinase 3
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase
NAP1L1 nucleosome assembly protein 1-like 1
NME2 NME/NM23 nucleoside diphosphate kinase 2
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
PARP4 poly (ADP-ribose) polymerase family, member 4
PCBP1 poly(rC) binding protein 1
PCBP2 poly(rC) binding protein 2
PEX5 peroxisomal biogenesis factor 5
PLEC plectin
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP6C protein phosphatase 6, catalytic subunit
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRKG1 protein kinase, cGMP-dependent, type I
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PTBP1 polypyrimidine tract binding protein 1
PTGES3 prostaglandin E synthase 3 (cytosolic)
QPCTL glutaminyl-peptide cyclotransferase-like
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RCN2 reticulocalbin 2, EF-hand calcium binding domain
RNF7 ring finger protein 7
RPL23 ribosomal protein L23
RPL31 ribosomal protein L31
RPL5 ribosomal protein L5
RPL7 ribosomal protein L7
RPS17 ribosomal protein S17
RPS18 ribosomal protein S18
RPS27A ribosomal protein S27a
RPS3 ribosomal protein S3
RPS3A ribosomal protein S3A
RPS4X ribosomal protein S4, X-linked
RUVBL2 RuvB-like AAA ATPase 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SKP1 S-phase kinase-associated protein 1
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SMN2 survival of motor neuron 2, centromeric
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SPSB2 splA/ryanodine receptor domain and SOCS box containing 2
SPSB4 splA/ryanodine receptor domain and SOCS box containing 4
SQRDL sulfide quinone reductase-like (yeast)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSBP1 single-stranded DNA binding protein 1, mitochondrial
SSR4 signal sequence receptor, delta
STIP1 stress-induced phosphoprotein 1
STRAP serine/threonine kinase receptor associated protein
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
TCP1 t-complex 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TRIM21 tripartite motif containing 21
TUBB6 tubulin, beta 6 class V
TYK2 tyrosine kinase 2
UBC ubiquitin C
UCHL5 ubiquitin carboxyl-terminal hydrolase L5
VCP valosin containing protein
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
YBX1 Y box binding protein 1
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZSWIM8 zinc finger, SWIM-type containing 8