NOS3 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description nitric oxide synthase 3 (endothelial cell)|Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009] (NCBI Entrez Gene Database, 4846)
External Link http://www.ncbi.nlm.nih.gov/gene/4846
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126 interacting proteins for NOS3 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
A2M alpha-2-macroglobulin
ACTB actin, beta
ACTN2 actinin, alpha 2
ACTN4 actinin, alpha 4
AGTR1 angiotensin II receptor, type 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
BDKRB2 bradykinin receptor B2
BDNF brain-derived neurotrophic factor
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAV1 caveolin 1, caveolae protein, 22kDa
CCL11 chemokine (C-C motif) ligand 11
CD247 CD247 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD4 CD4 molecule
CDC37 cell division cycle 37
CDK5 cyclin-dependent kinase 5
CEP55 centrosomal protein 55kDa
CNGA1 cyclic nucleotide gated channel alpha 1
CNGA3 cyclic nucleotide gated channel alpha 3
CNGB1 cyclic nucleotide gated channel beta 1
CNGB3 cyclic nucleotide gated channel beta 3
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR3 chemokine (C-X-C motif) receptor 3
DHFR dihydrofolate reductase
EDNRB endothelin receptor type B
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
ELAVL1 ELAV like RNA binding protein 1
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
EXOC6 exocyst complex component 6
EXOSC1 exosome component 1
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
FLNA filamin A, alpha
FZD2 frizzled class receptor 2
GCDH glutaryl-CoA dehydrogenase
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNG2 guanine nucleotide binding protein (G protein), gamma 2
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
GUCY1B3 guanylate cyclase 1, soluble, beta 3
H3F3A H3 histone, family 3A
HBA2 hemoglobin, alpha 2
HDAC3 histone deacetylase 3
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HTRA1 HtrA serine peptidase 1
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IMMT inner membrane protein, mitochondrial
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JAK1 Janus kinase 1
JAK2 Janus kinase 2
KANK2 KN motif and ankyrin repeat domains 2
KDR kinase insert domain receptor
LCK LCK proto-oncogene, Src family tyrosine kinase
LYPLA1 lysophospholipase I
MAST1 microtubule associated serine/threonine kinase 1
MPRIP myosin phosphatase Rho interacting protein
NMT1 N-myristoyltransferase 1
NOSIP nitric oxide synthase interacting protein
NOSTRIN nitric oxide synthase trafficking
NRG1 neuregulin 1
ORAI1 ORAI calcium release-activated calcium modulator 1
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PF4 platelet factor 4
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKCQ protein kinase C, theta
PRKG1 protein kinase, cGMP-dependent, type I
PRKG2 protein kinase, cGMP-dependent, type II
PSEN1 presenilin 1
PSEN2 presenilin 2
PTK2B protein tyrosine kinase 2 beta
QDPR quinoid dihydropteridine reductase
RNF31 ring finger protein 31
RNF32 ring finger protein 32
SH3BP2 SH3-domain binding protein 2
SIRT1 sirtuin 1
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SP1 Sp1 transcription factor
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
TECR trans-2,3-enoyl-CoA reductase
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TXNDC11 thioredoxin domain containing 11
UBC ubiquitin C
UMPS uridine monophosphate synthetase
VEGFA vascular endothelial growth factor A
WNT5A wingless-type MMTV integration site family, member 5A
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZDHHC21 zinc finger, DHHC-type containing 21