NOSIP Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description nitric oxide synthase interacting protein|The protein encoded by this gene may modulate the activity and localization of nitric oxide synthase (endothelial and neuronal) and thus nitric oxide production. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2012] (NCBI Entrez Gene Database, 51070)
Similar Terms
Downloads & Tools

Genes

337 genes differentially expressed following the NOSIP gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
TMEM71 transmembrane protein 71 2.69029
PON3 paraoxonase 3 2.69029
ZNF726 zinc finger protein 726 2.69029
LRRIQ4 leucine-rich repeats and IQ motif containing 4 2.69029
WDR64 WD repeat domain 64 2.69029
TAS2R5 taste receptor, type 2, member 5 2.69029
GJA9 gap junction protein, alpha 9, 59kDa 2.69029
DPF3 D4, zinc and double PHD fingers, family 3 2.69029
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 2.69029
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 2.69029
FBLN7 fibulin 7 2.69029
FIBIN fin bud initiation factor homolog (zebrafish) 2.69029
PODNL1 podocan-like 1 2.69029
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 2.69029
OR52E5 olfactory receptor, family 52, subfamily E, member 5 2.69029
CNTN3 contactin 3 (plasmacytoma associated) 2.69029
CLIC5 chloride intracellular channel 5 2.69029
KYNU kynureninase 2.69029
S100B S100 calcium binding protein B 2.69029
UFSP1 UFM1-specific peptidase 1 (non-functional) 2.69029
PTGFR prostaglandin F receptor (FP) 2.69029
MFAP4 microfibrillar-associated protein 4 2.69029
IRF8 interferon regulatory factor 8 2.69029
IZUMO1 izumo sperm-egg fusion 1 2.69029
CPN2 carboxypeptidase N, polypeptide 2 2.69029
PTGER3 prostaglandin E receptor 3 (subtype EP3) 2.69029
RACK1 receptor for activated C kinase 1 2.69029
ARHGAP20 Rho GTPase activating protein 20 2.69029
ASIC3 acid sensing (proton gated) ion channel 3 2.58368
NXPE1 neurexophilin and PC-esterase domain family, member 1 2.58368
TEX101 testis expressed 101 2.58368
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung) 2.58368
HNF4A hepatocyte nuclear factor 4, alpha 2.58368
FAM3D family with sequence similarity 3, member D 2.58368
CPLX1 complexin 1 2.58368
SLC35D3 solute carrier family 35, member D3 2.58368
SLC22A16 solute carrier family 22 (organic cation/carnitine transporter), member 16 2.58368
LOX lysyl oxidase 2.58368
KLF17 Kruppel-like factor 17 2.58368
ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 2.58368
AGTR1 angiotensin II receptor, type 1 2.58368
UNC13C unc-13 homolog C (C. elegans) 2.58368
NKAPL NFKB activating protein-like 2.58368
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 2.58368
C8ORF48 chromosome 8 open reading frame 48 2.58368
TKTL1 transketolase-like 1 2.58368
LRRC52 leucine rich repeat containing 52 2.58368
DHH desert hedgehog 2.58368
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 2.58368
SPINT3 serine peptidase inhibitor, Kunitz type, 3 2.58368
DEGS2 delta(4)-desaturase, sphingolipid 2 2.58368
DCAF4L1 DDB1 and CUL4 associated factor 4-like 1 2.58368
LY86 lymphocyte antigen 86 2.58368
MYBPHL myosin binding protein H-like 2.58368
RELL2 RELT-like 2 2.58368
NXPH3 neurexophilin 3 2.58368
CARD18 caspase recruitment domain family, member 18 2.58368
ENTHD1 ENTH domain containing 1 2.58368
BSND barttin CLCNK-type chloride channel accessory beta subunit 2.58368
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 2.58368
MUC1 mucin 1, cell surface associated 2.58368
KCNRG potassium channel regulator 2.58368
EDAR ectodysplasin A receptor 2.58368
DNAAF19 dynein axonemal assembly factor 19 2.58368
ANGPTL8 angiopoietin like 8 2.58368
H1-6 H1.6 linker histone, cluster member 2.58368
SEPTIN14 septin 14 2.58368
ERVW-1 endogenous retrovirus group W, member 1 2.58368
YIPF7 Yip1 domain family, member 7 2.58368
AVPR1B arginine vasopressin receptor 1B 2.58368
CAPN9 calpain 9 2.58368
CATSPERH catsper channel auxiliary subunit eta 2.58368
FMO2 flavin containing monooxygenase 2 (non-functional) 2.58368
MLN motilin 2.58368
MINAR2 membrane integral NOTCH2 associated receptor 2 2.58368
CCDC187 coiled-coil domain containing 187 2.58368
TBC1D3I TBC1 domain family member 3I 2.58368
ADAMTSL4-AS2 ADAMTSL4 antisense RNA 2 2.58368
C17ORF113 chromosome 17 open reading frame 113 2.58368
LOC122526780 uncharacterized LOC122526780 2.58368
RHEX regulator of hemoglobinization and erythroid cell expansion 2.58368
SMIM31 small integral membrane protein 31 2.58368
SERTM2 serine rich and transmembrane domain containing 2 2.58368
CFAP107 cilia and flagella associated protein 107 2.58368
H4C13 H4 clustered histone 13 2.58368
TERB1 telomere repeat binding bouquet formation protein 1 2.58368
OR6F1 olfactory receptor, family 6, subfamily F, member 1 2.58368
TMPRSS7 transmembrane protease, serine 7 2.58368
C7 complement component 7 2.58368
PTCHD3 patched domain containing 3 2.58368
C7ORF57 chromosome 7 open reading frame 57 2.58368
CREB3L3 cAMP responsive element binding protein 3-like 3 2.58368
PRRT4 proline-rich transmembrane protein 4 2.58368
TLR8 toll-like receptor 8 2.58368
NPIPB9 nuclear pore complex interacting protein family, member B9 2.58368
UROC1 urocanate hydratase 1 2.58368
CBLN3 cerebellin 3 precursor 2.58368
AKR1D1 aldo-keto reductase family 1, member D1 2.58368
PGA3 pepsinogen 3, group I (pepsinogen A) 2.58368
VCX3A variable charge, X-linked 3A 2.58368
NEURL3 neuralized E3 ubiquitin protein ligase 3 2.58368
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1 2.58368
SAG S-antigen; retina and pineal gland (arrestin) 2.58368
MYEOV myeloma overexpressed 2.58368
TSPAN8 tetraspanin 8 2.58368
NDP Norrie disease (pseudoglioma) 2.58368
CCDC42 coiled-coil domain containing 42 2.58368
CNTN6 contactin 6 2.58368
FGFBP2 fibroblast growth factor binding protein 2 2.58368
FAM131C family with sequence similarity 131, member C 2.58368
DSG1 desmoglein 1 2.58368
GAL3ST2 galactose-3-O-sulfotransferase 2 2.58368
CT55 cancer/testis antigen 55 2.58368
CLDN34 claudin 34 2.58368
THTPA thiamine triphosphatase 2.58368
BTNL2 butyrophilin-like 2 2.58368
ETNPPL ethanolamine-phosphate phospho-lyase 2.58368
CDHR4 cadherin-related family member 4 2.58368
JSRP1 junctional sarcoplasmic reticulum protein 1 2.58368
WFDC8 WAP four-disulfide core domain 8 2.58368
RAD21L1 RAD21-like 1 (S. pombe) 2.58368
BRDT bromodomain, testis-specific 2.58368
LRRC43 leucine rich repeat containing 43 2.58368
RHAG Rh-associated glycoprotein 2.58368
RERGL RERG/RAS-like 2.58368
ZNF534 zinc finger protein 534 2.58368
POTEI POTE ankyrin domain family, member I 2.58368
PAGE2B P antigen family, member 2B 2.58368
ZMYND15 zinc finger, MYND-type containing 15 2.58368
CIDEA cell death-inducing DFFA-like effector a 2.58368
MOS v-mos Moloney murine sarcoma viral oncogene homolog 2.58368
TDRD10 tudor domain containing 10 2.58368
HUS1B HUS1 checkpoint homolog b (S. pombe) 2.58368
IL36R interleukin 36 receptor 2.58368
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 2.58368
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 2.58368
DDI1 DNA-damage inducible 1 homolog 1 (S. cerevisiae) 2.58368
IL25 interleukin 25 2.58368
CXORF58 chromosome X open reading frame 58 2.58368
MB myoglobin 2.58368
GOLGA8R golgin A8 family, member R 2.58368
NLRP14 NLR family, pyrin domain containing 14 2.58368
LHX2 LIM homeobox 2 2.58368
LHX9 LIM homeobox 9 2.58368
ATP10B ATPase, class V, type 10B 2.58368
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa 2.58368
MUCL1 mucin-like 1 2.58368
RGCC regulator of cell cycle 2.58368
EMILIN1 elastin microfibril interfacer 1 2.58368
VSTM1 V-set and transmembrane domain containing 1 2.58368
EPHA5 EPH receptor A5 2.58368
NT5DC4 5'-nucleotidase domain containing 4 2.58368
CTSE cathepsin E 2.58368
ITGA8 integrin, alpha 8 2.58368
TMPRSS13 transmembrane protease, serine 13 2.58368
DLL4 delta-like 4 (Drosophila) 2.58368
MNX1 motor neuron and pancreas homeobox 1 2.58368
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 2.58368
FGF7 fibroblast growth factor 7 2.58368
FABP12 fatty acid binding protein 12 2.58368
TRPV6 transient receptor potential cation channel, subfamily V, member 6 2.58368
SP5 Sp5 transcription factor 2.58368
CACNG1 calcium channel, voltage-dependent, gamma subunit 1 2.58368
TMC2 transmembrane channel-like 2 2.58368
RSPH1 radial spoke head 1 homolog (Chlamydomonas) 2.58368
VSX1 visual system homeobox 1 2.58368
B3GNT8 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 2.58368
S100A3 S100 calcium binding protein A3 2.58368
TDRD9 tudor domain containing 9 2.58368
UBE2W ubiquitin-conjugating enzyme E2W (putative) 2.58368
SLC5A11 solute carrier family 5 (sodium/inositol cotransporter), member 11 2.58368
AMDHD1 amidohydrolase domain containing 1 2.58368
BANF2 barrier to autointegration factor 2 2.58368
ADAM20 ADAM metallopeptidase domain 20 2.58368
ANGPTL3 angiopoietin-like 3 2.58368
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 2.58368
CDCP2 CUB domain containing protein 2 2.58368
ST18 suppression of tumorigenicity 18, zinc finger 2.58368
PITX3 paired-like homeodomain 3 2.58368
SLC9C2 solute carrier family 9, member C2 (putative) 2.58368
ZNF648 zinc finger protein 648 2.58368
SCAND1 SCAN domain containing 1 2.51247
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 2.45993
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 2.45462
NUP93 nucleoporin 93kDa 2.44724
EPN1 epsin 1 2.44006
CRHR2 corticotropin releasing hormone receptor 2 2.43808
LDLRAP1 low density lipoprotein receptor adaptor protein 1 2.43808
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 2.43808
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 2.4205
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1 2.38615
DLEU7 deleted in lymphocytic leukemia, 7 2.38615
MADD MAP-kinase activating death domain 2.37487
TMEM268 transmembrane protein 268 2.35351
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 2.34772
RFC3 replication factor C (activator 1) 3, 38kDa 2.34601
ARRB2 arrestin, beta 2 2.34151
HSPA8 heat shock 70kDa protein 8 2.32024
LOC390937 Ets2 repressor factor-like 2.30304
RRP1B ribosomal RNA processing 1B 2.30286
MT1X metallothionein 1X 2.30081
TAMM41 TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae) 2.25284
WHR1 winged helix repair factor 1 2.25284
UBE2T ubiquitin-conjugating enzyme E2T 2.24281
ARID1B AT rich interactive domain 1B (SWI1-like) 2.24168
ENSA endosulfine alpha 2.21453
RPL15 ribosomal protein L15 2.19621
FAM13C family with sequence similarity 13, member C 2.19429
SV2B synaptic vesicle glycoprotein 2B 2.18548
FGFR4 fibroblast growth factor receptor 4 2.18502
PPIL1 peptidylprolyl isomerase (cyclophilin)-like 1 2.18347
APLP2 amyloid beta (A4) precursor-like protein 2 2.17425
SAMD4A sterile alpha motif domain containing 4A 2.17313
GSDMB gasdermin B 2.17118
PIGC phosphatidylinositol glycan anchor biosynthesis, class C 2.15928
RPL19 ribosomal protein L19 2.15274
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 2.15274
SIK2 salt-inducible kinase 2 2.11589
GAREM2 GRB2 associated regulator of MAPK1 subtype 2 2.11589
SALL4 spalt-like transcription factor 4 2.10986
MYDGF myeloid-derived growth factor 2.10063
CLSTN2 calsyntenin 2 2.09303
WDR81 WD repeat domain 81 2.09303
OR3A2 olfactory receptor, family 3, subfamily A, member 2 2.09303
HHAT hedgehog acyltransferase 2.09303
ZNF879 zinc finger protein 879 2.07072
DGKE diacylglycerol kinase, epsilon 64kDa 2.06542
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 2.05535
ADCY5 adenylate cyclase 5 2.05535
CERS4 ceramide synthase 4 2.03707
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 2.03707
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8 2.03322
STARD7 StAR-related lipid transfer (START) domain containing 7 2.00913
ARG2 arginase 2 2.00913
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha 2.00913

decreased expression

Symbol Name Standardized Value
SBSPON somatomedin B and thrombospondin, type 1 domain containing -2.69029
CR2 complement component (3d/Epstein Barr virus) receptor 2 -2.69029
SEPTIN4 septin 4 -2.69029
TMEM234 transmembrane protein 234 -2.69029
STAT4 signal transducer and activator of transcription 4 -2.58368
CD200R1L CD200 receptor 1-like -2.58368
RGS20 regulator of G-protein signaling 20 -2.58368
ZXDB zinc finger, X-linked, duplicated B -2.58368
DZIP3 DAZ interacting zinc finger protein 3 -2.58368
GOLGA6L10 golgin A6 family-like 10 -2.58368
MUC16 mucin 16, cell surface associated -2.58368
TNRC18 trinucleotide repeat containing 18 -2.58368
XPO1 exportin 1 -2.58368
ZBTB22 zinc finger and BTB domain containing 22 -2.58368
INSYN2B inhibitory synaptic factor family member 2B -2.58368
MARCHF9 membrane associated ring-CH-type finger 9 -2.58368
FCHSD2 FCH and double SH3 domains 2 -2.58368
ADCK5 aarF domain containing kinase 5 -2.58368
ILDR2 immunoglobulin-like domain containing receptor 2 -2.58368
ZNF763 zinc finger protein 763 -2.58368
ZNF343 zinc finger protein 343 -2.58368
STBD1 starch binding domain 1 -2.57672
RUMY1 regulator of UNG2 and MKLN1 interacting yippee protein 1 -2.57672
EOLA1 endothelium and lymphocyte associated ASCH domain 1 -2.57672
TMPRSS11D transmembrane protease, serine 11D -2.57672
PIH1D1 PIH1 domain containing 1 -2.57469
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa -2.57462
CLTRN collectrin, amino acid transport regulator -2.54686
FEZF1 FEZ family zinc finger 1 -2.47704
DLG3 discs, large homolog 3 (Drosophila) -2.44006
NAPSA napsin A aspartic peptidase -2.43808
GPT glutamic-pyruvate transaminase (alanine aminotransferase) -2.43808
NELL1 NEL-like 1 (chicken) -2.43808
PFDN5 prefoldin subunit 5 -2.43808
COL7A1 collagen, type VII, alpha 1 -2.43808
NLRP10 NLR family, pyrin domain containing 10 -2.43808
SLC46A3 solute carrier family 46, member 3 -2.43808
RAI2 retinoic acid induced 2 -2.43808
IL2RB interleukin 2 receptor, beta -2.43808
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 -2.43808
TUBA3D tubulin, alpha 3d -2.43808
SP6 Sp6 transcription factor -2.43808
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 -2.43808
OR51M1 olfactory receptor, family 51, subfamily M, member 1 -2.43808
GAB3 GRB2-associated binding protein 3 -2.43808
ZDHHC11B zinc finger, DHHC-type containing 11B -2.43808
CCN5 cellular communication network factor 5 -2.43808
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 -2.43808
C2CD4C C2 calcium-dependent domain containing 4C -2.43808
RRH retinal pigment epithelium-derived rhodopsin homolog -2.43808
CHIT1 chitinase 1 (chitotriosidase) -2.43808
CFAP100 cilia and flagella associated protein 100 -2.43808
ABI3 ABI family, member 3 -2.43808
GPAT3 glycerol-3-phosphate acyltransferase 3 -2.43808
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 -2.43808
RIMOC1 RAB7A interacting MON1-CCZ1 complex subunit 1 -2.43808
NANOS2 nanos homolog 2 (Drosophila) -2.43808
GALNT9 polypeptide N-acetylgalactosaminyltransferase 9 -2.43808
BATF2 basic leucine zipper transcription factor, ATF-like 2 -2.43808
RAD1 RAD1 checkpoint DNA exonuclease -2.37487
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 -2.35351
P3H1 prolyl 3-hydroxylase 1 -2.33679
TCEANC transcription elongation factor A (SII) N-terminal and central domain containing -2.33679
SRRM5 serine/arginine repetitive matrix 5 -2.33679
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -2.32681
PRPF31 pre-mRNA processing factor 31 -2.31549
NSUN6 NOP2/Sun domain family, member 6 -2.31333
CGGBP1 CGG triplet repeat binding protein 1 -2.30286
MECP2 methyl CpG binding protein 2 -2.29154
IL18BP interleukin 18 binding protein -2.25284
ROR1 receptor tyrosine kinase-like orphan receptor 1 -2.25284
SECISBP2 SECIS binding protein 2 -2.24048
NBEAL2 neurobeachin-like 2 -2.2172
HRK harakiri, BCL2 interacting protein -2.21497
UTP23 UTP23, small subunit (SSU) processome component, homolog (yeast) -2.20627
HLTF helicase-like transcription factor -2.20486
ACAD8 acyl-CoA dehydrogenase family, member 8 -2.19831
OSBPL1A oxysterol binding protein-like 1A -2.19429
GABARAPL2 GABA(A) receptor-associated protein-like 2 -2.1797
C15ORF40 chromosome 15 open reading frame 40 -2.17624
PRKDC protein kinase, DNA-activated, catalytic polypeptide -2.16717
ZNF652 zinc finger protein 652 -2.13897
MID2 midline 2 -2.12544
CHRM5 cholinergic receptor, muscarinic 5 -2.10725
SFRP1 secreted frizzled-related protein 1 -2.0953
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 -2.09303
ERBB2 erb-b2 receptor tyrosine kinase 2 -2.09303
KLHL9 kelch-like family member 9 -2.09303
SURF1 surfeit 1 -2.07072
MPC2 mitochondrial pyruvate carrier 2 -2.06718
KIF15 kinesin family member 15 -2.06412
GTF3C6 general transcription factor IIIC, polypeptide 6, alpha 35kDa -2.06378
CLDN11 claudin 11 -2.05543
RTCB RNA 2',3'-cyclic phosphate and 5'-OH ligase -2.05158
NDUFB10 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa -2.0462
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2 -2.03968
TRIB3 tribbles pseudokinase 3 -2.03968
MAGEL2 melanoma antigen family L2 -2.03968
SLC61A1 solute carrier family 61 member 1 -2.03707
MAST2 microtubule associated serine/threonine kinase 2 -2.0248
ZDHHC5 zinc finger, DHHC-type containing 5 -2.00913
CDH7 cadherin 7, type 2 -2.00913