| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | notch 2|This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011] (NCBI Entrez Gene Database, 4853) |
| External Link | https://ncbi.nlm.nih.gov/gene/4853 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the NOTCH2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COG7 | component of oligomeric golgi complex 7 | 0.0200672 |
| S100P | S100 calcium binding protein P | 0.0189527 |
| NEBL | nebulette | 0.0146532 |
| TFF1 | trefoil factor 1 | 0.0142132 |
| LTF | lactotransferrin | 0.0139507 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0135563 |
| AOC1 | amine oxidase, copper containing 1 | 0.0130368 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.012488 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.0120267 |
| AREG | amphiregulin | 0.01192 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.0118609 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0118553 |
| CAPN3 | calpain 3, (p94) | 0.01183 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0118286 |
| INHBA | inhibin, beta A | 0.0116172 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.0115288 |
| LCN2 | lipocalin 2 | 0.0114524 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.0113172 |
| GPX2 | glutathione peroxidase 2 | 0.0113059 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0111944 |
| FERMT1 | fermitin family member 1 | 0.0111227 |
| FAM107A | family with sequence similarity 107, member A | 0.0109448 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0109388 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.0109219 |
| KRT5 | keratin 5, type II | 0.0108773 |
| RGS1 | regulator of G-protein signaling 1 | 0.0107512 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.0107184 |
| CTSS | cathepsin S | 0.010587 |
| TSPAN1 | tetraspanin 1 | 0.0104289 |
| TATDN2 | TatD DNase domain containing 2 | 0.0103745 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.0102908 |
| IL2RG | interleukin 2 receptor, gamma | 0.0102437 |
| ABAT | 4-aminobutyrate aminotransferase | 0.0102126 |
| PADI2 | peptidyl arginine deiminase, type II | 0.0101686 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.01014 |
| TARP | TCR gamma alternate reading frame protein | 0.0101229 |
| KRT14 | keratin 14, type I | 0.0100426 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.010036 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.0100029 |
| ANXA3 | annexin A3 | 0.00993398 |
| RGS10 | regulator of G-protein signaling 10 | 0.00986672 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00981427 |
| FABP7 | fatty acid binding protein 7, brain | 0.00968 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.00962466 |
| LAMC2 | laminin, gamma 2 | 0.00958332 |
| FCGBP | Fc fragment of IgG binding protein | 0.00951356 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | 0.00949206 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | 0.00945146 |
| ITM2C | integral membrane protein 2C | 0.00941155 |
| ADD3 | adducin 3 (gamma) | 0.00940249 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.00939902 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 | 0.00931128 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.00928447 |
| TP53I3 | tumor protein p53 inducible protein 3 | 0.00914117 |
| TRIM29 | tripartite motif containing 29 | 0.00910703 |
| PALLD | palladin, cytoskeletal associated protein | 0.00908194 |
| PROS1 | protein S (alpha) | 0.0090481 |
| DIPK1A | divergent protein kinase domain 1A | 0.00903542 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.0089362 |
| RCAN1 | regulator of calcineurin 1 | 0.00893189 |
| TRIM16 | tripartite motif containing 16 | 0.00892973 |
| MSRB2 | methionine sulfoxide reductase B2 | 0.00890749 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00887589 |
| FBLN5 | fibulin 5 | 0.00886268 |
| LXN | latexin | 0.00885413 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.00885136 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 0.00881692 |
| GPX1 | glutathione peroxidase 1 | 0.0087905 |
| THBS2 | thrombospondin 2 | 0.00877004 |
| ANXA6 | annexin A6 | 0.00875376 |
| MSMB | microseminoprotein, beta- | 0.00871487 |
| THBS1 | thrombospondin 1 | 0.00869472 |
| CES1 | carboxylesterase 1 | 0.008623 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00850521 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0084858 |
| TMEM176A | transmembrane protein 176A | 0.00844637 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.00844337 |
| SDC1 | syndecan 1 | 0.00844033 |
| SMAGP | small cell adhesion glycoprotein | 0.00842541 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00841934 |
| ITGB4 | integrin, beta 4 | 0.00835682 |
| TJP2 | tight junction protein 2 | 0.00833351 |
| RBM34 | RNA binding motif protein 34 | 0.00832394 |
| PYCARD | PYD and CARD domain containing | 0.00830331 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 0.00829844 |
| SLA | Src-like-adaptor | 0.00829244 |
| ACP5 | acid phosphatase 5, tartrate resistant | 0.00828238 |
| SLC35D2 | solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 | 0.00823746 |
| CNTN1 | contactin 1 | 0.00819146 |
| PLAUR | plasminogen activator, urokinase receptor | 0.00815804 |
| KRT6B | keratin 6B, type II | 0.00810999 |
| CCN2 | cellular communication network factor 2 | 0.00809385 |
| KRT6A | keratin 6A, type II | 0.00809314 |
| TNNC1 | troponin C type 1 (slow) | 0.00808936 |
| ECM1 | extracellular matrix protein 1 | 0.00802942 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00799216 |
| MX1 | MX dynamin-like GTPase 1 | 0.0079648 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | 0.00795557 |
| CLIC3 | chloride intracellular channel 3 | 0.0079286 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.00786374 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00782755 |
| RNASET2 | ribonuclease T2 | 0.00778531 |
| PSCA | prostate stem cell antigen | 0.00773049 |
| TADA2A | transcriptional adaptor 2A | 0.00769901 |
| TRIP6 | thyroid hormone receptor interactor 6 | 0.00768493 |
| MSLN | mesothelin | 0.00767314 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.00767143 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | 0.00764579 |
| CLTB | clathrin, light chain B | 0.0076345 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.00758967 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00756639 |
| OPTN | optineurin | 0.00755898 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00755045 |
| PRTN3 | proteinase 3 | 0.00754159 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.0075353 |
| LAPTM5 | lysosomal protein transmembrane 5 | 0.00753046 |
| S100A14 | S100 calcium binding protein A14 | 0.00752537 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.00751668 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00749043 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.00746466 |
| NPC2 | Niemann-Pick disease, type C2 | 0.00744787 |
| CFB | complement factor B | 0.00739892 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00736842 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.00733461 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | 0.00731351 |
| INAVA | innate immunity activator | 0.00730886 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0072971 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | 0.00729349 |
| WASHC4 | WASH complex subunit 4 | 0.0072559 |
| HTRA1 | HtrA serine peptidase 1 | 0.00725228 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | 0.00724529 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00724414 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | 0.00722125 |
| CAPG | capping protein (actin filament), gelsolin-like | 0.00721781 |
| NMRK1 | nicotinamide riboside kinase 1 | 0.00717298 |
| PODXL | podocalyxin-like | 0.00716181 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.0071475 |
| HBEGF | heparin-binding EGF-like growth factor | 0.00714673 |
| FOSL2 | FOS-like antigen 2 | 0.00712202 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.00711359 |
| CFDP1 | craniofacial development protein 1 | 0.00709795 |
| LGALS9 | lectin, galactoside-binding, soluble, 9 | 0.00708183 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.00707767 |
| BPI | bactericidal/permeability-increasing protein | 0.0070683 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.00705125 |
| PRPF4 | pre-mRNA processing factor 4 | 0.00703681 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.00702912 |
| SELPLG | selectin P ligand | 0.00699853 |
| CH25H | cholesterol 25-hydroxylase | 0.00698532 |
| TLK2 | tousled-like kinase 2 | 0.00698148 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00695976 |
| CAST | calpastatin | 0.00695296 |
| PLLP | plasmolipin | 0.00695262 |
| PUF60 | poly-U binding splicing factor 60KDa | 0.00692148 |
| MXRA7 | matrix-remodelling associated 7 | 0.0069135 |
| JMJD6 | jumonji domain containing 6 | 0.00690873 |
| TICAM1 | toll-like receptor adaptor molecule 1 | 0.00690458 |
| IFITM2 | interferon induced transmembrane protein 2 | 0.0068859 |
| RNASE6 | ribonuclease, RNase A family, k6 | 0.00687873 |
| TDRD7 | tudor domain containing 7 | 0.00687757 |
| NRCAM | neuronal cell adhesion molecule | 0.00687068 |
| C3AR1 | complement component 3a receptor 1 | 0.0068454 |
| BCAS1 | breast carcinoma amplified sequence 1 | 0.00683801 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.00683226 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 0.0068283 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00681764 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.00681277 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.00677112 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | 0.00675733 |
| FGF1 | fibroblast growth factor 1 (acidic) | 0.00672621 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase | 0.00672458 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00672406 |
| CHP1 | calcineurin-like EF-hand protein 1 | 0.00671386 |
| PNMA2 | paraneoplastic Ma antigen 2 | 0.006712 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.00670382 |
| MAP7 | microtubule-associated protein 7 | 0.00670033 |
| IRS2 | insulin receptor substrate 2 | 0.00669449 |
| STOM | stomatin | 0.00669002 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | 0.00668053 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.00667938 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | 0.00666938 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00666079 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.00664835 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00663707 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 0.00662632 |
| RTP4 | receptor (chemosensory) transporter protein 4 | 0.00661602 |
| GNAL | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type | 0.00661499 |
| IFI35 | interferon-induced protein 35 | 0.00660612 |
| PERP | PERP, TP53 apoptosis effector | 0.00660215 |
| RNF167 | ring finger protein 167 | 0.00658853 |
| BCL2A1 | BCL2-related protein A1 | 0.00658289 |
| FGFBP1 | fibroblast growth factor binding protein 1 | 0.00654197 |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 | 0.00652794 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00651438 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00649625 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.00649281 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | 0.00647375 |
| CEL | carboxyl ester lipase | 0.00645025 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00644511 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.00642546 |
| NKG7 | natural killer cell granule protein 7 | 0.00641264 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.00640235 |
| EVI2A | ecotropic viral integration site 2A | 0.00640088 |
| PHYH | phytanoyl-CoA 2-hydroxylase | 0.00639061 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D | 0.00639061 |
| TSPAN8 | tetraspanin 8 | 0.00637777 |
| SH3BGR | SH3 domain binding glutamate-rich protein | 0.00637647 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.00635345 |
| TPBG | trophoblast glycoprotein | 0.00634839 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.00633906 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | 0.00631237 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 | 0.00630584 |
| GZMK | granzyme K (granzyme 3; tryptase II) | 0.00630496 |
| HAUS4 | HAUS augmin-like complex, subunit 4 | 0.0063045 |
| IFRD2 | interferon-related developmental regulator 2 | 0.00629124 |
| TRH | thyrotropin-releasing hormone | 0.00628771 |
| PEBP1 | phosphatidylethanolamine binding protein 1 | 0.00628098 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.00625612 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.00625524 |
| CDC20 | cell division cycle 20 | 0.00624481 |
| SLAMF7 | SLAM family member 7 | 0.00623652 |
| ABLIM1 | actin binding LIM protein 1 | 0.0062365 |
| CTSD | cathepsin D | 0.00623131 |
| DPEP1 | dipeptidase 1 (renal) | 0.00622286 |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 | 0.00621664 |
| C3 | complement component 3 | 0.00620361 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.00618978 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.00618173 |
| TRAF3IP2 | TRAF3 interacting protein 2 | 0.00617967 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.00617927 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 0.0061701 |
| KCNQ1 | potassium channel, voltage gated KQT-like subfamily Q, member 1 | 0.00616793 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.00616327 |
| CD38 | CD38 molecule | 0.00616031 |
| IFI44L | interferon-induced protein 44-like | 0.00614681 |
| ACAT1 | acetyl-CoA acetyltransferase 1 | 0.00612086 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | 0.00612001 |
| OTULINL | OTU deubiquitinase with linear linkage specificity like | 0.00610423 |
| CLDN8 | claudin 8 | 0.00607912 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.00606726 |
| IRF1 | interferon regulatory factor 1 | 0.00605614 |
| CDK18 | cyclin-dependent kinase 18 | 0.00604979 |
| PCNA | proliferating cell nuclear antigen | 0.00602157 |
| KIF1C | kinesin family member 1C | 0.00598496 |
| ATRAID | all-trans retinoic acid-induced differentiation factor | 0.0059579 |
| C1ORF54 | chromosome 1 open reading frame 54 | 0.00595482 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00595022 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | 0.00592048 |
| EML2 | echinoderm microtubule associated protein like 2 | 0.00591246 |
| AK1 | adenylate kinase 1 | 0.00591044 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SSBP2 | single-stranded DNA binding protein 2 | -0.0287249 |
| CLU | clusterin | -0.0135937 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.011828 |
| DCLK1 | doublecortin-like kinase 1 | -0.0115849 |
| CNN3 | calponin 3, acidic | -0.0105832 |
| PANK3 | pantothenate kinase 3 | -0.0103786 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.0100162 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00993317 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.00989762 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00980861 |
| TMSB15A | thymosin beta 15a | -0.00947792 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -0.00924984 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0092199 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00919659 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0091851 |
| NTS | neurotensin | -0.00905734 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0090073 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | -0.00882475 |
| ARG2 | arginase 2 | -0.0087505 |
| TCTA | T-cell leukemia translocation altered | -0.00855937 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.00848964 |
| HOXC6 | homeobox C6 | -0.00845274 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.00842305 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | -0.00833832 |
| CCNG2 | cyclin G2 | -0.00833612 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00832658 |
| SYBU | syntabulin (syntaxin-interacting) | -0.00828414 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | -0.00822097 |
| OLFM1 | olfactomedin 1 | -0.00821361 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.00821227 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00816883 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.00809475 |
| SCAF4 | SR-related CTD-associated factor 4 | -0.00805106 |
| CADM1 | cell adhesion molecule 1 | -0.00804932 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.00799311 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | -0.00799111 |
| WT1 | Wilms tumor 1 | -0.00798328 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | -0.00794621 |
| CHN1 | chimerin 1 | -0.00789181 |
| CBX6 | chromobox homolog 6 | -0.00786302 |
| RGS13 | regulator of G-protein signaling 13 | -0.00785012 |
| MB | myoglobin | -0.00781634 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | -0.0077824 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.00768648 |
| CYB5A | cytochrome b5 type A (microsomal) | -0.00767932 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00767602 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | -0.00762158 |
| NDP | Norrie disease (pseudoglioma) | -0.0075905 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00755124 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.00750469 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.00747606 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.00745772 |
| PMP22 | peripheral myelin protein 22 | -0.00740227 |
| CSAD | cysteine sulfinic acid decarboxylase | -0.00735734 |
| ESR1 | estrogen receptor 1 | -0.00732322 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) | -0.00727673 |
| RUFY2 | RUN and FYVE domain containing 2 | -0.00725794 |
| HCRT | hypocretin (orexin) neuropeptide precursor | -0.00725299 |
| ORC1 | origin recognition complex, subunit 1 | -0.00722077 |
| CTSA | cathepsin A | -0.00721293 |
| PRPF4B | pre-mRNA processing factor 4B | -0.00718169 |
| E2F8 | E2F transcription factor 8 | -0.00718109 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00715995 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00710482 |
| RAPSN | receptor-associated protein of the synapse | -0.00705238 |
| CST6 | cystatin E/M | -0.00703581 |
| HIST1H2BD | histone cluster 1, H2bd | -0.00702052 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | -0.00694234 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.00693505 |
| SST | somatostatin | -0.0068978 |
| RAD51AP1 | RAD51 associated protein 1 | -0.00687832 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | -0.00686969 |
| SPC25 | SPC25, NDC80 kinetochore complex component | -0.00682611 |
| FABP6 | fatty acid binding protein 6, ileal | -0.00675622 |
| TSC22D1 | TSC22 domain family, member 1 | -0.00673383 |
| FBXO5 | F-box protein 5 | -0.00673324 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | -0.00669999 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | -0.0066978 |
| MPPED2 | metallophosphoesterase domain containing 2 | -0.00662259 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | -0.00659407 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.00654447 |
| FAM13B | family with sequence similarity 13, member B | -0.00653952 |
| APOB | apolipoprotein B | -0.00653912 |
| HAUS3 | HAUS augmin-like complex, subunit 3 | -0.00653176 |
| TSPO | translocator protein (18kDa) | -0.00651974 |
| GYG2 | glycogenin 2 | -0.0065181 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 | -0.00649625 |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 | -0.00649623 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.00648618 |
| EDNRB | endothelin receptor type B | -0.00647831 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.00647807 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.00647321 |
| NBEA | neurobeachin | -0.0064569 |
| BCHE | butyrylcholinesterase | -0.00644714 |
| MPHOSPH9 | M-phase phosphoprotein 9 | -0.00643966 |
| MAOA | monoamine oxidase A | -0.00641628 |
| GSTT1 | glutathione S-transferase theta 1 | -0.00639362 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.00635828 |
| STC2 | stanniocalcin 2 | -0.00635563 |
| SPON2 | spondin 2, extracellular matrix protein | -0.00635173 |
| RAI2 | retinoic acid induced 2 | -0.00634205 |
| PCGF3 | polycomb group ring finger 3 | -0.00632582 |
| PLA1A | phospholipase A1 member A | -0.00630038 |
| ZNF304 | zinc finger protein 304 | -0.00627165 |
| CROCCP2 | ciliary rootlet coiled-coil, rootletin pseudogene 2 | -0.00625551 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) | -0.00624601 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00624382 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.00623079 |
| MGLL | monoglyceride lipase | -0.00621838 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.00621817 |
| FADS1 | fatty acid desaturase 1 | -0.00621485 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | -0.00620476 |
| EDRF1 | erythroid differentiation regulatory factor 1 | -0.00619302 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | -0.00618542 |
| FASTKD3 | FAST kinase domains 3 | -0.00618114 |
| COL3A1 | collagen, type III, alpha 1 | -0.00617847 |
| CHKB | choline kinase beta | -0.00616304 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.00615657 |
| REG1B | regenerating islet-derived 1 beta | -0.00614758 |
| KIF18A | kinesin family member 18A | -0.0061417 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific | -0.00613868 |
| FAM13A | family with sequence similarity 13, member A | -0.00613083 |
| H1-2 | H1.2 linker histone, cluster member | -0.00613083 |
| HAPLN1 | hyaluronan and proteoglycan link protein 1 | -0.00611386 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00609715 |
| RGS3 | regulator of G-protein signaling 3 | -0.00607955 |
| BAD | BCL2-associated agonist of cell death | -0.00605324 |
| SHROOM2 | shroom family member 2 | -0.00604855 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | -0.00603785 |
| SC5D | sterol-C5-desaturase | -0.00602823 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.00601362 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.00601067 |
| MMP2 | matrix metallopeptidase 2 | -0.00599205 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.00598287 |
| EFR3A | EFR3 homolog A (S. cerevisiae) | -0.00597068 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.00594131 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.00593809 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | -0.00592266 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.00592206 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.00591555 |
| G0S2 | G0/G1 switch 2 | -0.00591497 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.00590743 |
| TXLNA | taxilin alpha | -0.0058779 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | -0.00587671 |
| ZKSCAN7 | zinc finger with KRAB and SCAN domains 7 | -0.00585763 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00583988 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | -0.00582227 |
| C1ORF115 | chromosome 1 open reading frame 115 | -0.00581515 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.0057942 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00577964 |
| MDM1 | Mdm1 nuclear protein homolog (mouse) | -0.00577558 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | -0.00574714 |
| EZR | ezrin | -0.00572476 |
| FBXO3 | F-box protein 3 | -0.00571126 |
| MAP3K7CL | MAP3K7 C-terminal like | -0.00570032 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | -0.00569293 |
| CREBZF | CREB/ATF bZIP transcription factor | -0.00568109 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | -0.0056806 |
| KIF23 | kinesin family member 23 | -0.00566695 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.00565234 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.00564128 |
| ASPH | aspartate beta-hydroxylase | -0.00564032 |
| NDUFB6 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa | -0.00563154 |
| FADS3 | fatty acid desaturase 3 | -0.00562368 |
| EFNA5 | ephrin-A5 | -0.00561588 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | -0.00560409 |
| MRPL49 | mitochondrial ribosomal protein L49 | -0.00559816 |
| TFRC | transferrin receptor | -0.00559787 |
| GPAA1 | glycosylphosphatidylinositol anchor attachment 1 | -0.00558102 |
| NRN1 | neuritin 1 | -0.0055803 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | -0.00557999 |
| FAM193A | family with sequence similarity 193, member A | -0.00557524 |
| PAEP | progestagen-associated endometrial protein | -0.00557058 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.00556304 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | -0.00555185 |
| OTUD3 | OTU deubiquitinase 3 | -0.00554972 |
| HMGN5 | high mobility group nucleosome binding domain 5 | -0.00554611 |
| RACGAP1 | Rac GTPase activating protein 1 | -0.00554578 |
| RBM26 | RNA binding motif protein 26 | -0.00554419 |
| YEATS4 | YEATS domain containing 4 | -0.00554294 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | -0.00553227 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | -0.00550934 |
| ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A | -0.00550453 |
| ARGLU1 | arginine and glutamate rich 1 | -0.00549615 |
| CD99 | CD99 molecule | -0.00549597 |
| SRP9 | signal recognition particle 9kDa | -0.00549382 |
| REG3A | regenerating islet-derived 3 alpha | -0.00549348 |
| FZD2 | frizzled class receptor 2 | -0.00549302 |
| RUFY3 | RUN and FYVE domain containing 3 | -0.00548088 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | -0.00547204 |
| FOXF1 | forkhead box F1 | -0.00546396 |
| FNBP1L | formin binding protein 1-like | -0.00544545 |
| MECP2 | methyl CpG binding protein 2 | -0.00543069 |
| FAM172A | family with sequence similarity 172, member A | -0.00543023 |
| ATP5ME | ATP synthase membrane subunit e | -0.00542848 |
| HOXD1 | homeobox D1 | -0.00542704 |
| TUSC3 | tumor suppressor candidate 3 | -0.0054203 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | -0.00540999 |
| NHLRC2 | NHL repeat containing 2 | -0.00538175 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00537885 |
| KPNA6 | karyopherin alpha 6 (importin alpha 7) | -0.00537761 |
| SDC3 | syndecan 3 | -0.00537601 |
| YTHDC2 | YTH domain containing 2 | -0.00537514 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.00536738 |
| GAL | galanin/GMAP prepropeptide | -0.00536527 |
| LOX | lysyl oxidase | -0.00536269 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.00535231 |
| DICER1 | dicer 1, ribonuclease type III | -0.0053503 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.00534914 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.00534855 |
| SAC3D1 | SAC3 domain containing 1 | -0.00533964 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.00532681 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00532302 |
| PSPH | phosphoserine phosphatase | -0.00532011 |
| PIGG | phosphatidylinositol glycan anchor biosynthesis, class G | -0.00531443 |
| SLC33A1 | solute carrier family 33 (acetyl-CoA transporter), member 1 | -0.00531314 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.00529692 |
| PRAME | preferentially expressed antigen in melanoma | -0.00529057 |
| SEPHS2 | selenophosphate synthetase 2 | -0.00528792 |
| JADE1 | jade family PHD finger 1 | -0.00528709 |
| ZNF83 | zinc finger protein 83 | -0.00527378 |
| AADAC | arylacetamide deacetylase | -0.00526094 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | -0.00525305 |
| INHBB | inhibin, beta B | -0.00525261 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | -0.00525021 |
| ZNF12 | zinc finger protein 12 | -0.00524191 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 | -0.00523487 |
| ZNF711 | zinc finger protein 711 | -0.00520869 |
| TMEM70 | transmembrane protein 70 | -0.0052027 |
| ATP8A2 | ATPase, aminophospholipid transporter, class I, type 8A, member 2 | -0.00520047 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00519716 |
| TTTY15 | testis-specific transcript, Y-linked 15 (non-protein coding) | -0.00519714 |
| APOA1 | apolipoprotein A-I | -0.00519397 |
| LOXL1 | lysyl oxidase-like 1 | -0.00517577 |
| SHCBP1 | SHC SH2-domain binding protein 1 | -0.00517065 |
| ZNF551 | zinc finger protein 551 | -0.00516953 |
| MREG | melanoregulin | -0.00516492 |
| WBP5 | WW domain binding protein 5 | -0.00516432 |
| KLF3-AS1 | KLF3 antisense RNA 1 | -0.00513221 |
| HTR3A | 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic | -0.00511105 |
| NVL | nuclear VCP-like | -0.00510732 |
| ELOC | elongin C | -0.0051034 |
| SETMAR | SET domain and mariner transposase fusion gene | -0.00509548 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.0050884 |
| WWC3 | WWC family member 3 | -0.00507517 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00505951 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | -0.00505595 |
| OBSL1 | obscurin-like 1 | -0.00505048 |
| EML3 | echinoderm microtubule associated protein like 3 | -0.00504988 |
