NPC2 Gene Set

Dataset	Pathway Commons Protein-Protein Interactions
Category	physical interactions
Type	interacting protein
Description	Niemann-Pick disease, type C2\|This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 10577)
External Link	http://www.ncbi.nlm.nih.gov/gene/10577
Similar Terms
Downloads & Tools

Genes

13 interacting proteins for NPC2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol	Name
BARD1	BRCA1 associated RING domain 1
BRCA1	breast cancer 1, early onset
DHDDS	dehydrodolichyl diphosphate synthase
ECT2	epithelial cell transforming 2
LIG4	ligase IV, DNA, ATP-dependent
NDUFV2	NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NPC1	Niemann-Pick disease, type C1
NUDT19	nudix (nucleoside diphosphate linked moiety X)-type motif 19
PAXIP1	PAX interacting (with transcription-activation domain) protein 1
SLC9A3R2	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
UBC	ubiquitin C
USP4	ubiquitin specific peptidase 4 (proto-oncogene)