NR1H4 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description nuclear receptor subfamily 1, group H, member 4|This gene encodes a ligand-activated transcription factor, which shares structural features in common with nuclear hormone receptor family, such as a DNA-binding domain that targets the receptor to specific DNA sequences, and a ligand-binding domain, which interacts directly with the ligand and contains a ligand-dependent transcriptional activation domain. This protein functions as a receptor for bile acids, and when bound to bile acids, regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011] (NCBI Entrez Gene Database, 9971)
External Link http://www.ncbi.nlm.nih.gov/gene/9971
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Genes

44 interacting proteins for NR1H4 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ACTN2 actinin, alpha 2
AKAP9 A kinase (PRKA) anchor protein 9
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CARM1 coactivator-associated arginine methyltransferase 1
CASP8 caspase 8, apoptosis-related cysteine peptidase
DLG4 discs, large homolog 4 (Drosophila)
EP300 E1A binding protein p300
ESR1 estrogen receptor 1
FABP6 fatty acid binding protein 6, ileal
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GPS2 G protein pathway suppressor 2
GRB2 growth factor receptor-bound protein 2
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D
HDAC6 histone deacetylase 6
HIST1H3B histone cluster 1, H3b
HIST1H4F histone cluster 1, H4f
NCOA1 nuclear receptor coactivator 1
NCOA6 nuclear receptor coactivator 6
NCOR1 nuclear receptor corepressor 1
NCOR2 nuclear receptor corepressor 2
NEFL neurofilament, light polypeptide
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRKCA protein kinase C, alpha
PRKCZ protein kinase C, zeta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRMT1 protein arginine methyltransferase 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RRM2 ribonucleotide reductase M2
RXRA retinoid X receptor, alpha
RXRG retinoid X receptor, gamma
SIRT1 sirtuin 1
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SUMO1 small ubiquitin-like modifier 1
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6