| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | nuclear receptor subfamily 1, group I, member 2|This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 8856) |
| External Link | https://ncbi.nlm.nih.gov/gene/8856 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the NR1I2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TFF1 | trefoil factor 1 | 0.0175672 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.016096 |
| SFRP1 | secreted frizzled-related protein 1 | 0.0158863 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.0151952 |
| OLFM4 | olfactomedin 4 | 0.0132536 |
| RRAGA | Ras-related GTP binding A | 0.0127861 |
| LTF | lactotransferrin | 0.0116254 |
| S100P | S100 calcium binding protein P | 0.0115216 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.0110552 |
| TFF3 | trefoil factor 3 (intestinal) | 0.0109436 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.010855 |
| NEBL | nebulette | 0.0106882 |
| METRN | meteorin, glial cell differentiation regulator | 0.0105561 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.0101384 |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 | 0.00993249 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.00992048 |
| MAP7 | microtubule-associated protein 7 | 0.00961526 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.00951332 |
| GSTT1 | glutathione S-transferase theta 1 | 0.00949155 |
| TGM2 | transglutaminase 2 | 0.00924431 |
| MMP7 | matrix metallopeptidase 7 | 0.0089768 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00894787 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.00887567 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.00884312 |
| GPX2 | glutathione peroxidase 2 | 0.00872759 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00868733 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.00854074 |
| EFNB2 | ephrin-B2 | 0.00852357 |
| DIXDC1 | DIX domain containing 1 | 0.00849907 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00844216 |
| ELAPOR1 | endosome-lysosome associated apoptosis and autophagy regulator 1 | 0.00839059 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | 0.00837343 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.00831435 |
| MLPH | melanophilin | 0.00823425 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.0081739 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 0.00813479 |
| MMP3 | matrix metallopeptidase 3 | 0.00811972 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0081104 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.00808099 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.00806291 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.00805359 |
| OSR2 | odd-skipped related transciption factor 2 | 0.00804357 |
| CARD10 | caspase recruitment domain family, member 10 | 0.00793347 |
| SQLE | squalene epoxidase | 0.00776806 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.00776317 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0077411 |
| KRT19 | keratin 19, type I | 0.00769546 |
| APOD | apolipoprotein D | 0.00768428 |
| EFHD2 | EF-hand domain family, member D2 | 0.00768302 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.00767426 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00767066 |
| MGLL | monoglyceride lipase | 0.0076106 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.00760263 |
| TST | thiosulfate sulfurtransferase (rhodanese) | 0.00754538 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00749314 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.00743332 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.00736281 |
| PLPP2 | phospholipid phosphatase 2 | 0.0073592 |
| G6PD | glucose-6-phosphate dehydrogenase | 0.00734569 |
| BCR | breakpoint cluster region | 0.00730561 |
| HIP1R | huntingtin interacting protein 1 related | 0.00722245 |
| MYO5C | myosin VC | 0.00720526 |
| SLC25A1 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | 0.00719739 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.00718055 |
| PROM1 | prominin 1 | 0.00715709 |
| ACTA1 | actin, alpha 1, skeletal muscle | 0.00711663 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.00708301 |
| PAX5 | paired box 5 | 0.00705852 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.00705462 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.00703288 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.00702316 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00694981 |
| TGFA | transforming growth factor, alpha | 0.00693709 |
| TBC1D16 | TBC1 domain family, member 16 | 0.00693517 |
| ACTC1 | actin, alpha, cardiac muscle 1 | 0.00691459 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.00690493 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.00688895 |
| HEPH | hephaestin | 0.00687393 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.00685777 |
| RHOB | ras homolog family member B | 0.00682596 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.00680311 |
| CST3 | cystatin C | 0.00678546 |
| MB | myoglobin | 0.00673446 |
| TRIB2 | tribbles pseudokinase 2 | 0.00671244 |
| STC1 | stanniocalcin 1 | 0.00668785 |
| XYLT1 | xylosyltransferase I | 0.00663416 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00662802 |
| MSMB | microseminoprotein, beta- | 0.00660065 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | 0.00659548 |
| FLNA | filamin A, alpha | 0.00659082 |
| XIC | X chromosome inactivation center | 0.00656959 |
| UBE2S | ubiquitin-conjugating enzyme E2S | 0.00654787 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.00653843 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | 0.00653227 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.00651967 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.006489 |
| AOC1 | amine oxidase, copper containing 1 | 0.00646697 |
| PRR7 | proline rich 7 (synaptic) | 0.00644993 |
| GATA2 | GATA binding protein 2 | 0.0064467 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) | 0.0064366 |
| JAK1 | Janus kinase 1 | 0.00641915 |
| SMTN | smoothelin | 0.0064156 |
| VWF | von Willebrand factor | 0.00640843 |
| REG3A | regenerating islet-derived 3 alpha | 0.00640732 |
| MPST | mercaptopyruvate sulfurtransferase | 0.00638814 |
| PLXNB2 | plexin B2 | 0.00638361 |
| AKAP1 | A kinase (PRKA) anchor protein 1 | 0.00637248 |
| LMOD1 | leiomodin 1 (smooth muscle) | 0.00636844 |
| DES | desmin | 0.00635942 |
| SYNM | synemin, intermediate filament protein | 0.00634773 |
| PRSS8 | protease, serine, 8 | 0.00633261 |
| SORD | sorbitol dehydrogenase | 0.00632771 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.00631593 |
| RTN2 | reticulon 2 | 0.00630423 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00629769 |
| IL7R | interleukin 7 receptor | 0.00629496 |
| MAGED1 | melanoma antigen family D1 | 0.00629033 |
| CD79A | CD79a molecule, immunoglobulin-associated alpha | 0.00624334 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.00620301 |
| H1-0 | H1.0 linker histone | 0.00619914 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | 0.00619886 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) | 0.00619564 |
| PDLIM5 | PDZ and LIM domain 5 | 0.00619459 |
| DGKZ | diacylglycerol kinase, zeta | 0.00619343 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | 0.00618817 |
| GLB1L2 | galactosidase, beta 1-like 2 | 0.00618509 |
| CNN1 | calponin 1, basic, smooth muscle | 0.00616653 |
| CORO1B | coronin, actin binding protein, 1B | 0.00614638 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.00614627 |
| ABHD2 | abhydrolase domain containing 2 | 0.00611885 |
| LDB3 | LIM domain binding 3 | 0.00609873 |
| STK26 | serine/threonine protein kinase 26 | 0.00608269 |
| FASN | fatty acid synthase | 0.00607847 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.00602153 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.00600044 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.00598567 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.00597409 |
| COL14A1 | collagen, type XIV, alpha 1 | 0.00597132 |
| HMG20B | high mobility group 20B | 0.00595022 |
| FILIP1L | filamin A interacting protein 1-like | 0.00594759 |
| TWF2 | twinfilin actin binding protein 2 | 0.00591963 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00591892 |
| PLK1 | polo-like kinase 1 | 0.0059071 |
| FHL1 | four and a half LIM domains 1 | 0.00589922 |
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | 0.00588286 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.00587845 |
| FBLN5 | fibulin 5 | 0.00586217 |
| MAP2K2 | mitogen-activated protein kinase kinase 2 | 0.00585849 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.00585159 |
| TRIM28 | tripartite motif containing 28 | 0.00584805 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 0.00584162 |
| VARS | valyl-tRNA synthetase | 0.00584108 |
| SPAG1 | sperm associated antigen 1 | 0.00582442 |
| CFD | complement factor D (adipsin) | 0.00581624 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00581544 |
| HIRA | histone cell cycle regulator | 0.00580892 |
| EXOSC4 | exosome component 4 | 0.00579856 |
| KHK | ketohexokinase (fructokinase) | 0.0057889 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | 0.00578371 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00577844 |
| CD81 | CD81 molecule | 0.00577826 |
| BIN1 | bridging integrator 1 | 0.00577394 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.00577091 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.00575324 |
| TOB1 | transducer of ERBB2, 1 | 0.00574251 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | 0.00571315 |
| CARM1 | coactivator-associated arginine methyltransferase 1 | 0.00570885 |
| ABLIM1 | actin binding LIM protein 1 | 0.00570144 |
| NEK2 | NIMA-related kinase 2 | 0.00567547 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | 0.0056624 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.00565435 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 0.00565301 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.00565098 |
| PNKP | polynucleotide kinase 3'-phosphatase | 0.00563539 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.00563104 |
| POR | P450 (cytochrome) oxidoreductase | 0.00563077 |
| LIPG | lipase, endothelial | 0.00562856 |
| CLDN3 | claudin 3 | 0.00562394 |
| LMNB2 | lamin B2 | 0.0056066 |
| MARCKSL1 | MARCKS-like 1 | 0.00560504 |
| IRF6 | interferon regulatory factor 6 | 0.00560459 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00559474 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 0.00559368 |
| NELFB | negative elongation factor complex member B | 0.00559086 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 0.00557975 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific | 0.00557302 |
| MCM7 | minichromosome maintenance complex component 7 | 0.00555832 |
| TLCD3A | TLC domain containing 3A | 0.00553016 |
| WSB2 | WD repeat and SOCS box containing 2 | 0.00552422 |
| H1-10 | H1.10 linker histone | 0.00552077 |
| ICA1 | islet cell autoantigen 1, 69kDa | 0.00551171 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 0.00550596 |
| KIAA0930 | KIAA0930 | 0.00548022 |
| ALDOB | aldolase B, fructose-bisphosphate | 0.00547493 |
| LCN2 | lipocalin 2 | 0.00545591 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00544344 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00544042 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | 0.0054387 |
| ISOC2 | isochorismatase domain containing 2 | 0.00543313 |
| TRAF5 | TNF receptor-associated factor 5 | 0.0054295 |
| SLC44A4 | solute carrier family 44, member 4 | 0.00541579 |
| MANSC1 | MANSC domain containing 1 | 0.00541479 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.00540138 |
| ZNF652 | zinc finger protein 652 | 0.00538748 |
| STXBP2 | syntaxin binding protein 2 | 0.00538027 |
| KLK11 | kallikrein-related peptidase 11 | 0.00537865 |
| TSPYL5 | TSPY-like 5 | 0.00534292 |
| PALLD | palladin, cytoskeletal associated protein | 0.0053409 |
| ZNF12 | zinc finger protein 12 | 0.00533349 |
| BLNK | B-cell linker | 0.00533337 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.00532841 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 0.00532176 |
| SCAMP4 | secretory carrier membrane protein 4 | 0.00531762 |
| UBE2M | ubiquitin-conjugating enzyme E2M | 0.00529909 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 0.00529215 |
| PDE4A | phosphodiesterase 4A, cAMP-specific | 0.00528989 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00528612 |
| TNNC1 | troponin C type 1 (slow) | 0.00527399 |
| IFT122 | intraflagellar transport 122 | 0.00526932 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.00526016 |
| PRKCZ | protein kinase C, zeta | 0.00525181 |
| CTBP2 | C-terminal binding protein 2 | 0.00524957 |
| NKX3-1 | NK3 homeobox 1 | 0.00522465 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.00520658 |
| SAMM50 | SAMM50 sorting and assembly machinery component | 0.00518776 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00518199 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | 0.00518073 |
| ZSWIM8 | zinc finger, SWIM-type containing 8 | 0.00516715 |
| GALC | galactosylceramidase | 0.00516548 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 0.00516101 |
| AGBL5 | ATP/GTP binding protein-like 5 | 0.00516051 |
| PIGB | phosphatidylinositol glycan anchor biosynthesis, class B | 0.00516024 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.00514916 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | 0.00514835 |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.00514541 |
| MED22 | mediator complex subunit 22 | 0.0051445 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) | 0.00514294 |
| KRT23 | keratin 23, type I | 0.00513977 |
| TSPAN1 | tetraspanin 1 | 0.00513222 |
| GPX3 | glutathione peroxidase 3 | 0.00511621 |
| MED13 | mediator complex subunit 13 | 0.00510891 |
| SPON2 | spondin 2, extracellular matrix protein | 0.0051079 |
| PYCARD | PYD and CARD domain containing | 0.00510123 |
| TRAPPC12 | trafficking protein particle complex 12 | 0.00510034 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | 0.00510012 |
| LONP1 | lon peptidase 1, mitochondrial | 0.00509821 |
| AK1 | adenylate kinase 1 | 0.00509405 |
| HOXC6 | homeobox C6 | 0.00509039 |
| IQCE | IQ motif containing E | 0.00508925 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.0187427 |
| XPO7 | exportin 7 | -0.0131068 |
| EIF5 | eukaryotic translation initiation factor 5 | -0.011647 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.0115363 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0111895 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0109143 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0108916 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0105939 |
| HOPX | HOP homeobox | -0.0104618 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.00965008 |
| BEX1 | brain expressed, X-linked 1 | -0.00964884 |
| FN1 | fibronectin 1 | -0.00956367 |
| LRRC17 | leucine rich repeat containing 17 | -0.00919648 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -0.00919572 |
| PITX3 | paired-like homeodomain 3 | -0.00903743 |
| MEN1 | multiple endocrine neoplasia I | -0.00894958 |
| BTG3 | BTG family, member 3 | -0.00887773 |
| CADM1 | cell adhesion molecule 1 | -0.00873514 |
| CA2 | carbonic anhydrase II | -0.00864151 |
| BCHE | butyrylcholinesterase | -0.00853496 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00848005 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00844422 |
| HSPA13 | heat shock protein 70kDa family, member 13 | -0.00834281 |
| APOC1 | apolipoprotein C-I | -0.00806019 |
| MT1F | metallothionein 1F | -0.00794829 |
| SRGN | serglycin | -0.0079368 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00784132 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00769318 |
| RGS4 | regulator of G-protein signaling 4 | -0.00766568 |
| MCL1 | myeloid cell leukemia 1 | -0.00755825 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | -0.00754383 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.00750767 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | -0.00746438 |
| TRAM1 | translocation associated membrane protein 1 | -0.00742095 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00739737 |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) | -0.00738175 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.00728036 |
| REEP5 | receptor accessory protein 5 | -0.00726527 |
| CEL | carboxyl ester lipase | -0.0072002 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00711939 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00708537 |
| SELENOF | selenoprotein F | -0.00708232 |
| MOCS2 | molybdenum cofactor synthesis 2 | -0.00703749 |
| SCG5 | secretogranin V | -0.00701214 |
| THBS2 | thrombospondin 2 | -0.00699082 |
| HAL | histidine ammonia-lyase | -0.00694853 |
| MYH10 | myosin, heavy chain 10, non-muscle | -0.0069247 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | -0.0069059 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.00678728 |
| IL6ST | interleukin 6 signal transducer | -0.00675167 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | -0.0067143 |
| HIST1H2AC | histone cluster 1, H2ac | -0.00667069 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00666573 |
| NREP | neuronal regeneration related protein | -0.00657104 |
| CTBS | chitobiase, di-N-acetyl- | -0.00656488 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 | -0.00652595 |
| FGG | fibrinogen gamma chain | -0.00649361 |
| CD200 | CD200 molecule | -0.00647709 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -0.0064621 |
| S100A2 | S100 calcium binding protein A2 | -0.00641706 |
| SPRR1B | small proline-rich protein 1B | -0.00640178 |
| ATF3 | activating transcription factor 3 | -0.00638671 |
| EVI2A | ecotropic viral integration site 2A | -0.00637863 |
| WT1 | Wilms tumor 1 | -0.00637813 |
| CNPY3 | canopy FGF signaling regulator 3 | -0.00635159 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | -0.00631654 |
| GMFG | glia maturation factor, gamma | -0.00627265 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -0.00624883 |
| DCTN6 | dynactin 6 | -0.00623049 |
| TYRP1 | tyrosinase-related protein 1 | -0.00622557 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00619822 |
| CTH | cystathionine gamma-lyase | -0.00616796 |
| THBS1 | thrombospondin 1 | -0.00616686 |
| RGS1 | regulator of G-protein signaling 1 | -0.00616272 |
| COL3A1 | collagen, type III, alpha 1 | -0.00613331 |
| MIR22HG | MIR22 host gene | -0.00613013 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | -0.00612377 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | -0.00611795 |
| ZNF415 | zinc finger protein 415 | -0.00610911 |
| NARS2 | asparaginyl-tRNA synthetase 2, mitochondrial (putative) | -0.0060853 |
| IFI44L | interferon-induced protein 44-like | -0.0060772 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.00605308 |
| LAPTM5 | lysosomal protein transmembrane 5 | -0.0060399 |
| MRPL18 | mitochondrial ribosomal protein L18 | -0.00601048 |
| SCARB2 | scavenger receptor class B, member 2 | -0.00600857 |
| SFTPA2 | surfactant protein A2 | -0.00600499 |
| MT1E | metallothionein 1E | -0.00599031 |
| CD53 | CD53 molecule | -0.00599006 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.00597661 |
| HLA-C | major histocompatibility complex, class I, C | -0.00596207 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -0.00595979 |
| MAL | mal, T-cell differentiation protein | -0.00593619 |
| SLC38A2 | solute carrier family 38, member 2 | -0.00592541 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00580381 |
| GAP43 | growth associated protein 43 | -0.00579992 |
| TMEM50B | transmembrane protein 50B | -0.0057985 |
| KLF6 | Kruppel-like factor 6 | -0.00579268 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.00577844 |
| EPYC | epiphycan | -0.0057602 |
| MXRA5 | matrix-remodelling associated 5 | -0.00574858 |
| SSR1 | signal sequence receptor, alpha | -0.00573447 |
| SPRR2B | small proline-rich protein 2B | -0.00572861 |
| TUSC3 | tumor suppressor candidate 3 | -0.00571696 |
| ANOS1 | anosmin 1 | -0.00568834 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | -0.00568208 |
| DCTN4 | dynactin 4 (p62) | -0.00563169 |
| PNO1 | partner of NOB1 homolog (S. cerevisiae) | -0.0056312 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | -0.00562979 |
| HAX1 | HCLS1 associated protein X-1 | -0.00560435 |
| MT2A | metallothionein 2A | -0.00559428 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0055864 |
| RGCC | regulator of cell cycle | -0.00555776 |
| PRDX6 | peroxiredoxin 6 | -0.00554584 |
| PLS3 | plastin 3 | -0.00553693 |
| FOXD1 | forkhead box D1 | -0.00553114 |
| BST2 | bone marrow stromal cell antigen 2 | -0.00552402 |
| RNF14 | ring finger protein 14 | -0.00551247 |
| CD99 | CD99 molecule | -0.00550169 |
| SLC12A8 | solute carrier family 12, member 8 | -0.00550117 |
| PRNP | prion protein | -0.00549992 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.00547573 |
| S100A4 | S100 calcium binding protein A4 | -0.00547435 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0054537 |
| LDHA | lactate dehydrogenase A | -0.00545101 |
| GTF2B | general transcription factor IIB | -0.00544142 |
| SPP1 | secreted phosphoprotein 1 | -0.00543989 |
| HLA-B | major histocompatibility complex, class I, B | -0.00542986 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 | -0.00542889 |
| ENSA | endosulfine alpha | -0.00540975 |
| AP4S1 | adaptor-related protein complex 4, sigma 1 subunit | -0.0053928 |
| AK2 | adenylate kinase 2 | -0.00538091 |
| LYPD1 | LY6/PLAUR domain containing 1 | -0.00536819 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.00535887 |
| TGFB3 | transforming growth factor, beta 3 | -0.00534799 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | -0.0053333 |
| PSMA1 | proteasome (prosome, macropain) subunit, alpha type, 1 | -0.00532593 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00531851 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00531115 |
| MT1HL1 | metallothionein 1H-like 1 | -0.00530785 |
| GLMN | glomulin, FKBP associated protein | -0.00528792 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -0.00528489 |
| KRT5 | keratin 5, type II | -0.00527926 |
| WRN | Werner syndrome, RecQ helicase-like | -0.0052659 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00526461 |
| TREM2 | triggering receptor expressed on myeloid cells 2 | -0.00526327 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00525996 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.00525096 |
| PRPH | peripherin | -0.00524314 |
| TMEM230 | transmembrane protein 230 | -0.00522976 |
| ZNF14 | zinc finger protein 14 | -0.0052263 |
| PSAT1 | phosphoserine aminotransferase 1 | -0.00522375 |
| RAB1A | RAB1A, member RAS oncogene family | -0.00522064 |
| TMEM100 | transmembrane protein 100 | -0.00521806 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.00521645 |
| HOXA1 | homeobox A1 | -0.00521438 |
| CTSB | cathepsin B | -0.00519566 |
| KRT10 | keratin 10, type I | -0.00519125 |
| SFTPB | surfactant protein B | -0.00517028 |
| GMFB | glia maturation factor, beta | -0.00516568 |
| C5ORF15 | chromosome 5 open reading frame 15 | -0.00514773 |
| TMED10 | transmembrane emp24-like trafficking protein 10 (yeast) | -0.00514268 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0051177 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | -0.00511643 |
| KIAA0125 | KIAA0125 | -0.00511246 |
| GPX7 | glutathione peroxidase 7 | -0.00511031 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.00510988 |
| GLO1 | glyoxalase I | -0.00510639 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | -0.00510486 |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit | -0.00507653 |
| SST | somatostatin | -0.0050744 |
| FKBP11 | FK506 binding protein 11, 19 kDa | -0.00507288 |
| SAR1B | secretion associated, Ras related GTPase 1B | -0.00506918 |
| GNG5 | guanine nucleotide binding protein (G protein), gamma 5 | -0.00505972 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.00505405 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -0.00505344 |
| DAPK1 | death-associated protein kinase 1 | -0.00503949 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00503665 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.00503481 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.00503313 |
| COMMD10 | COMM domain containing 10 | -0.00501484 |
| IFI44 | interferon-induced protein 44 | -0.00500144 |
| GLRB | glycine receptor, beta | -0.00499982 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.00498918 |
| MINDY3 | MINDY lysine 48 deubiquitinase 3 | -0.00498643 |
| STAB1 | stabilin 1 | -0.00498186 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.00497582 |
| COL11A1 | collagen, type XI, alpha 1 | -0.00493275 |
| AZU1 | azurocidin 1 | -0.00493121 |
| LYPLA1 | lysophospholipase I | -0.0049266 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | -0.0049236 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | -0.00492235 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | -0.00491681 |
| MT1G | metallothionein 1G | -0.00491216 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00490395 |
| YIPF5 | Yip1 domain family, member 5 | -0.0049036 |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 | -0.00489733 |
| CHIT1 | chitinase 1 (chitotriosidase) | -0.00489535 |
| ATP5F1C | ATP synthase F1 subunit gamma | -0.004893 |
| NVL | nuclear VCP-like | -0.00488674 |
| RDX | radixin | -0.00488611 |
| BEX4 | brain expressed, X-linked 4 | -0.00484888 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.0048349 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.00483162 |
| POLR3G | polymerase (RNA) III (DNA directed) polypeptide G (32kD) | -0.00482222 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.00482137 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | -0.00480629 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0047953 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00479274 |
| TMED5 | transmembrane emp24 protein transport domain containing 5 | -0.00478772 |
| MT1M | metallothionein 1M | -0.00478419 |
| HLA-F | major histocompatibility complex, class I, F | -0.00478398 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) | -0.00478292 |
| RIT1 | Ras-like without CAAX 1 | -0.00477643 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.00476351 |
| KRT17 | keratin 17, type I | -0.00475959 |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A | -0.00475217 |
| TM2D1 | TM2 domain containing 1 | -0.00474783 |
| S100A9 | S100 calcium binding protein A9 | -0.00473841 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -0.00473204 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.00473178 |
| HMBOX1 | homeobox containing 1 | -0.00473165 |
| GGCX | gamma-glutamyl carboxylase | -0.00472764 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.00471766 |
| ARMCX3 | armadillo repeat containing, X-linked 3 | -0.00471393 |
| MAT2B | methionine adenosyltransferase II, beta | -0.00470162 |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta | -0.00469901 |
| MT3 | metallothionein 3 | -0.00469805 |
| GLDC | glycine dehydrogenase (decarboxylating) | -0.00469183 |
| AQP1 | aquaporin 1 (Colton blood group) | -0.00469024 |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 | -0.0046899 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | -0.00468601 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00467451 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | -0.00466635 |
| MTMR9 | myotubularin related protein 9 | -0.00465843 |
| RIDA | reactive intermediate imine deaminase A homolog | -0.00465737 |
| IDH3A | isocitrate dehydrogenase 3 (NAD+) alpha | -0.00464847 |
| GNAS | GNAS complex locus | -0.00464571 |
| GEMIN2 | gem (nuclear organelle) associated protein 2 | -0.00463969 |
| EXOC5 | exocyst complex component 5 | -0.00463365 |
| MPP5 | membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) | -0.0046304 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | -0.00462907 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.00462461 |
| CRIPT | cysteine-rich PDZ-binding protein | -0.00461886 |
| HLA-G | major histocompatibility complex, class I, G | -0.00461687 |
| ZNF43 | zinc finger protein 43 | -0.00460089 |
| MT1H | metallothionein 1H | -0.00459817 |
| SYT11 | synaptotagmin XI | -0.00459695 |
| PER1 | period circadian clock 1 | -0.00458996 |
| PIGK | phosphatidylinositol glycan anchor biosynthesis, class K | -0.00458816 |
| AHR | aryl hydrocarbon receptor | -0.00458675 |
