NR2C2 Gene Set

Dataset JASPAR Predicted Transcription Factor Targets
Category genomics
Type transcription factor
Description nuclear receptor subfamily 2, group C, member 2|This gene encodes a protein that belongs to the nuclear hormone receptor family. Members of this family act as ligand-activated transcription factors and function in many biological processes such as development, cellular differentiation and homeostasis. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. The protein encoded by this gene plays a role in protecting cells from oxidative stress and damage induced by ionizing radiation. The lack of a similar gene in mouse results in growth retardation, severe spinal curvature, subfertility, premature aging, and prostatic intraepithelial neoplasia (PIN) development. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014] (NCBI Entrez Gene Database, 7182)
External Link http://www.ncbi.nlm.nih.gov/gene/7182
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Genes

66 target genes of the NR2C2 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.

Symbol Name
AGBL2 ATP/GTP binding protein-like 2
APOE apolipoprotein E
ARMC5 armadillo repeat containing 5
AZIN1 antizyme inhibitor 1
BRD7 bromodomain containing 7
CARD10 caspase recruitment domain family, member 10
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
CCDC71 coiled-coil domain containing 71
CD160 CD160 molecule
CDC34 cell division cycle 34
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CLDN15 claudin 15
CSTA cystatin A (stefin A)
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
EFHC1 EF-hand domain (C-terminal) containing 1
EMC10 ER membrane protein complex subunit 10
EMG1 EMG1 N1-specific pseudouridine methyltransferase
F7 coagulation factor VII (serum prothrombin conversion accelerator)
GALR2 galanin receptor 2
HBP1 HMG-box transcription factor 1
ICMT isoprenylcysteine carboxyl methyltransferase
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IL27RA interleukin 27 receptor, alpha
INSL3 insulin-like 3 (Leydig cell)
ISCA1 iron-sulfur cluster assembly 1
ITFG2 integrin alpha FG-GAP repeat containing 2
LHCGR luteinizing hormone/choriogonadotropin receptor
LINGO1 leucine rich repeat and Ig domain containing 1
MAGEB18 melanoma antigen family B18
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MEN1 multiple endocrine neoplasia I
MMP11 matrix metallopeptidase 11
MTMR8 myotubularin related protein 8
MYOZ1 myozenin 1
NSUN5 NOP2/Sun domain family, member 5
NT5DC1 5'-nucleotidase domain containing 1
NUDT17 nudix (nucleoside diphosphate linked moiety X)-type motif 17
PKD2L1 polycystic kidney disease 2-like 1
PLCH2 phospholipase C, eta 2
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
POLR3GL polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
PRR34 proline rich 34
PSMG4 proteasome (prosome, macropain) assembly chaperone 4
RAD18 RAD18 E3 ubiquitin protein ligase
RBM38 RNA binding motif protein 38
RET ret proto-oncogene
RGS19 regulator of G-protein signaling 19
RP1 retinitis pigmentosa 1 (autosomal dominant)
RPH3A rabphilin 3A
SCAMP3 secretory carrier membrane protein 3
SEH1L SEH1-like (S. cerevisiae)
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC45A3 solute carrier family 45, member 3
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa
SPA17 sperm autoantigenic protein 17
SRP68 signal recognition particle 68kDa
STRN striatin, calmodulin binding protein
TBC1D14 TBC1 domain family, member 14
TPO thyroid peroxidase
TTYH2 tweety family member 2
TULP2 tubby like protein 2
UGT3A1 UDP glycosyltransferase 3 family, polypeptide A1
WDR83 WD repeat domain 83
ZFC3H1 zinc finger, C3H1-type containing
ZFP28 ZFP28 zinc finger protein