NR2E1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description nuclear receptor subfamily 2, group E, member 1| (NCBI Entrez Gene Database, 7101)
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Genes

357 genes differentially expressed following the NR2E1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
DNASE1L2 deoxyribonuclease I-like 2 3.15938
GNAT3 guanine nucleotide binding protein, alpha transducing 3 3.15938
GMFG glia maturation factor, gamma 3.15938
UBA7 ubiquitin-like modifier activating enzyme 7 3.15938
CPB1 carboxypeptidase B1 (tissue) 3.15938
OC90 otoconin 90 3.15938
TAS2R10 taste receptor, type 2, member 10 3.15938
TAS2R19 taste receptor, type 2, member 19 3.15938
LGALS2 lectin, galactoside-binding, soluble, 2 3.15938
CPLX3 complexin 3 3.15938
SPACA3 sperm acrosome associated 3 3.15938
ADAMTSL5 ADAMTS-like 5 3.15938
TRAT1 T cell receptor associated transmembrane adaptor 1 3.15938
GLUD2 glutamate dehydrogenase 2 3.15938
CELA3A chymotrypsin-like elastase family, member 3A 3.15938
PON1 paraoxonase 1 3.15938
SLC35G6 solute carrier family 35, member G6 3.15938
ADTRP androgen-dependent TFPI-regulating protein 3.15938
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene) 3.15938
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 3.15938
FOLR2 folate receptor 2 (fetal) 3.15938
TUBB1 tubulin, beta 1 class VI 3.15938
KCNRG potassium channel regulator 3.15938
NMUR1 neuromedin U receptor 1 3.15938
ARSH arylsulfatase family, member H 3.15938
ANGPTL5 angiopoietin-like 5 3.15938
TRAF3IP3 TRAF3 interacting protein 3 3.15938
OR10G3 olfactory receptor, family 10, subfamily G, member 3 3.15938
TGM6 transglutaminase 6 3.15938
TGM4 transglutaminase 4 3.15938
TTC36 tetratricopeptide repeat domain 36 3.15938
TOMM5 translocase of outer mitochondrial membrane 5 homolog (yeast) 3.15938
A1CF APOBEC1 complementation factor 3.15938
CCNO cyclin O 3.15938
EPN3 epsin 3 3.15938
ACSM2A acyl-CoA synthetase medium-chain family member 2A 3.15938
OXER1 oxoeicosanoid (OXE) receptor 1 3.15938
CNTN2 contactin 2 (axonal) 3.15938
MIXL1 Mix paired-like homeobox 3.15938
MEIG1 meiosis/spermiogenesis associated 1 3.15938
RBP4 retinol binding protein 4, plasma 3.15938
WFDC11 WAP four-disulfide core domain 11 3.15938
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 3.15938
SPINT4 serine peptidase inhibitor, Kunitz type 4 3.15938
C5ORF46 chromosome 5 open reading frame 46 3.15938
OR14A2 olfactory receptor, family 14, subfamily A, member 2 3.15938
IL17B interleukin 17B 3.15938
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 3.15938
CATSPERT catsper channel auxiliary subunit tau 3.15938
AVPR1B arginine vasopressin receptor 1B 3.15938
RSPH4A radial spoke head 4 homolog A (Chlamydomonas) 3.15938
NEURL3 neuralized E3 ubiquitin protein ligase 3 3.15938
ADRB1 adrenoceptor beta 1 3.15938
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 3.15938
SPATA25 spermatogenesis associated 25 3.15938
GPR37L1 G protein-coupled receptor 37 like 1 3.15938
PRDM7 PR domain containing 7 3.15938
HNF1B HNF1 homeobox B 3.15938
TIMD4 T-cell immunoglobulin and mucin domain containing 4 3.15938
ROPN1L rhophilin associated tail protein 1-like 3.15938
HPSE heparanase 3.15938
THSD8 thrombospondin type 1 domain containing 8 3.15938
CIMAP1B ciliary microtubule associated protein 1B 3.15938
LOC124903372 uncharacterized LOC124903372 3.15938
CCDC197 coiled-coil domain containing 197 3.15938
DNAAF6 dynein axonemal assembly factor 6 3.15938
GARIN1A golgi associated RAB2 interactor 1A 3.15938
ELOA2 elongin A2 3.15938
AJM1 apical junction component 1 homolog 3.15938
ALPG alkaline phosphatase, germ cell 3.15938
SAPCD1 suppressor APC domain containing 1 3.15938
RBM44 RNA binding motif protein 44 3.15938
SASH3 SAM and SH3 domain containing 3 3.15938
RGS9BP regulator of G protein signaling 9 binding protein 3.15938
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 3.15938
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 3.15938
LURAP1L leucine rich adaptor protein 1-like 3.15938
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 3.15938
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 3.15938
MC4R melanocortin 4 receptor 3.15938
CABP4 calcium binding protein 4 3.15938
NANOS2 nanos homolog 2 (Drosophila) 3.15938
TMEM176B transmembrane protein 176B 3.15938
ISM2 isthmin 2 3.15938
ELAVL4 ELAV like neuron-specific RNA binding protein 4 3.15938
PIWIL1 piwi-like RNA-mediated gene silencing 1 3.15938
SH3TC2 SH3 domain and tetratricopeptide repeats 2 3.15938
PDE1B phosphodiesterase 1B, calmodulin-dependent 3.15938
S1PR5 sphingosine-1-phosphate receptor 5 3.15938
LRIT3 leucine-rich repeat, immunoglobulin-like and transmembrane domains 3 3.15938
CATSPER3 cation channel, sperm associated 3 3.15938
OLAH oleoyl-ACP hydrolase 3.15938
PCDHB13 protocadherin beta 13 3.15938
IL12RB1 interleukin 12 receptor, beta 1 3.15938
LOC390937 Ets2 repressor factor-like 3.15938
TXNDC8 thioredoxin domain containing 8 (spermatozoa) 3.15938
DEFB107B defensin, beta 107B 3.15938
C2CD4B C2 calcium-dependent domain containing 4B 3.15938
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 3.15938
VWA3B von Willebrand factor A domain containing 3B 3.15938
IL11 interleukin 11 3.15938
HELT helt bHLH transcription factor 3.15938
RGCC regulator of cell cycle 3.15938
GTF2A1L general transcription factor IIA, 1-like 3.15938
CFAP47 cilia and flagella associated protein 47 3.15938
UTS2R urotensin 2 receptor 3.15938
FAM209A family with sequence similarity 209, member A 3.15938
KCTD21 potassium channel tetramerization domain containing 21 3.15938
IRGM immunity-related GTPase family, M 3.15938
DGCR6 DiGeorge syndrome critical region gene 6 3.15938
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 3.15938
FAM163A family with sequence similarity 163, member A 3.15938
KLF1 Kruppel-like factor 1 (erythroid) 3.15938
KLF4 Kruppel-like factor 4 (gut) 3.15938
HOXD3 homeobox D3 3.15938
HAVCR1 hepatitis A virus cellular receptor 1 3.15938
C16ORF78 chromosome 16 open reading frame 78 3.15938
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled 3.15938
HLA-DOA major histocompatibility complex, class II, DO alpha 3.15938
XKR3 XK, Kell blood group complex subunit-related family, member 3 3.15938
LYPD5 LY6/PLAUR domain containing 5 3.15938
TMPPE transmembrane protein with metallophosphoesterase domain 3.15938
NYX nyctalopin 3.15938
CNR2 cannabinoid receptor 2 (macrophage) 3.15938
CNGB1 cyclic nucleotide gated channel beta 1 3.15938
GJC2 gap junction protein, gamma 2, 47kDa 3.15938
BTG4 B-cell translocation gene 4 3.15938
GOLGA8K golgin A8 family, member K 3.15938
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 3.15938
LHX2 LIM homeobox 2 3.15938
NCR3 natural cytotoxicity triggering receptor 3 3.15938
F13B coagulation factor XIII, B polypeptide 3.15938
ACSBG2 acyl-CoA synthetase bubblegum family member 2 3.15938
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 3.15938
GDPD4 glycerophosphodiester phosphodiesterase domain containing 4 3.15938
SIGLEC16 sialic acid binding Ig-like lectin 16 (gene/pseudogene) 3.15938
XIRP2 xin actin binding repeat containing 2 3.15938
PRSS38 protease, serine, 38 3.15938
NR5A1 nuclear receptor subfamily 5, group A, member 1 3.15938
NT5C1B 5'-nucleotidase, cytosolic IB 3.15938
GPR62 G protein-coupled receptor 62 3.15938
MZB1 marginal zone B and B1 cell-specific protein 3.15938
TMEM132E transmembrane protein 132E 3.15938
POU3F3 POU class 3 homeobox 3 3.15938
PRR15L proline rich 15-like 3.15938
SHOX short stature homeobox 3.15938
IL12B interleukin 12B 3.15938
SCUBE2 signal peptide, CUB domain, EGF-like 2 3.15938
ARHGAP20 Rho GTPase activating protein 20 3.15938
HSPB9 heat shock protein, alpha-crystallin-related, B9 3.15938
MAGEB17 melanoma antigen family B17 3.15938
CCL25 chemokine (C-C motif) ligand 25 3.15938
CEACAM16 carcinoembryonic antigen-related cell adhesion molecule 16 3.15938
CCL24 chemokine (C-C motif) ligand 24 3.15938
OR3A1 olfactory receptor, family 3, subfamily A, member 1 3.15938
SP100 SP100 nuclear antigen 3.15938
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 3.15938
TSPAN32 tetraspanin 32 3.15938
MMP1 matrix metallopeptidase 1 3.15938
GH1 growth hormone 1 3.15938
KLHL5 kelch-like family member 5 3.15938
RAD51AP2 RAD51 associated protein 2 3.15938
C18ORF63 chromosome 18 open reading frame 63 3.15938
CRMP1 collapsin response mediator protein 1 3.14968
PRRT1 proline-rich transmembrane protein 1 3.10983
CPLANE2 ciliogenesis and planar polarity effector complex subunit 2 3.10314
ATP5F1D ATP synthase F1 subunit delta 3.07228
ADPRS ADP-ribosylserine hydrolase 3.01344
COL2A1 collagen, type II, alpha 1 2.97434
GOLGA8H golgin A8 family, member H 2.91967
MRPS21 mitochondrial ribosomal protein S21 2.85282
ATP5MC1 ATP synthase membrane subunit c locus 1 2.83963
TMX3 thioredoxin-related transmembrane protein 3 2.81869
TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) 2.81492
NAV1 neuron navigator 1 2.69901
DDT D-dopachrome tautomerase 2.64688
ARHGAP42 Rho GTPase activating protein 42 2.59471
DCDC2 doublecortin domain containing 2 2.59208
KLHL21 kelch-like family member 21 2.55883
MRPS12 mitochondrial ribosomal protein S12 2.55743
L3MBTL4 l(3)mbt-like 4 (Drosophila) 2.49109
EPHB4 EPH receptor B4 2.47906
TSPAN6 tetraspanin 6 2.46003
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit 2.46003
KCNK6 potassium channel, two pore domain subfamily K, member 6 2.43787
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2 2.43787
PIH1D1 PIH1 domain containing 1 2.43212
S100A10 S100 calcium binding protein A10 2.39144
RBM48 RNA binding motif protein 48 2.38461
WBP2NL WBP2 N-terminal like 2.37311
FOLR1 folate receptor 1 (adult) 2.37311
DNAAF3 dynein, axonemal, assembly factor 3 2.37209
SFT2D1 SFT2 domain containing 1 2.36671
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1) 2.36533
MSR1 macrophage scavenger receptor 1 2.35855
RIOK2 RIO kinase 2 2.34246
THUMPD1 THUMP domain containing 1 2.33146
SLK STE20-like kinase 2.33146
CERK ceramide kinase 2.32598
TMEM145 transmembrane protein 145 2.31387
DSEL dermatan sulfate epimerase-like 2.29065
UBR1 ubiquitin protein ligase E3 component n-recognin 1 2.28628
METTL25B methyltransferase like 25B 2.28628
FAM168A family with sequence similarity 168, member A 2.24467
TMEM158 transmembrane protein 158 (gene/pseudogene) 2.23726
RNASEH2C ribonuclease H2, subunit C 2.21636
GNG4 guanine nucleotide binding protein (G protein), gamma 4 2.21352
CD160 CD160 molecule 2.20834
OR6A2 olfactory receptor, family 6, subfamily A, member 2 2.20834
C19ORF84 chromosome 19 open reading frame 84 2.20834
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 2.20834
TMEM229B transmembrane protein 229B 2.20834
ZFP57 ZFP57 zinc finger protein 2.20834
SMNDC1 survival motor neuron domain containing 1 2.20653
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa 2.20573
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 2.20494
SAMHD1 SAM domain and HD domain 1 2.20108
CDC50A cell division cycle 50 P4-ATPase accessory subunit A 2.19658
MAN2A1 mannosidase, alpha, class 2A, member 1 2.19658
ELOVL6 ELOVL fatty acid elongase 6 2.19178
ACAD10 acyl-CoA dehydrogenase family, member 10 2.19178
SCRIB scribbled planar cell polarity protein 2.18605
GLTP glycolipid transfer protein 2.15241
NODAL nodal growth differentiation factor 2.14536
PTEN phosphatase and tensin homolog 2.13753
ALDH1L2 aldehyde dehydrogenase 1 family, member L2 2.11655
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 2.10067
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 2.08528
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 2.06145
GDI2 GDP dissociation inhibitor 2 2.06055
NICOL1 NELL2 interacting cell ontogeny regulator 1 2.05644
ZNF280B zinc finger protein 280B 2.04315
HBQ1 hemoglobin, theta 1 2.03889
ESRRG estrogen-related receptor gamma 2.03889
CC2D1B coiled-coil and C2 domain containing 1B 2.03423
RETREG3 reticulophagy regulator family member 3 2.02052
ANKRD6 ankyrin repeat domain 6 2.00631
LTN1 listerin E3 ubiquitin protein ligase 1 2.00276
NKAPD1 NKAP domain containing 1 2.00276

decreased expression

Symbol Name Standardized Value
SSH1 slingshot protein phosphatase 1 -3.15938
GLIPR1L1 GLI pathogenesis-related 1 like 1 -3.15938
ADPRH ADP-ribosylarginine hydrolase -3.15938
ANAPC2 anaphase promoting complex subunit 2 -3.15938
ISG20 interferon stimulated exonuclease gene 20kDa -3.15938
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein -3.15938
BRICD5 BRICHOS domain containing 5 -3.15938
GGACT gamma-glutamylamine cyclotransferase -3.14968
DES desmin -3.14968
NCR3LG1 natural killer cell cytotoxicity receptor 3 ligand 1 -3.14968
NPIPB15 nuclear pore complex interacting protein family, member B15 -3.14968
LCN2 lipocalin 2 -3.14968
RGL4 ral guanine nucleotide dissociation stimulator-like 4 -3.14968
CALCA calcitonin-related polypeptide alpha -3.14968
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 -3.14968
GFRA3 GDNF family receptor alpha 3 -3.14968
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma -3.14968
RAI2 retinoic acid induced 2 -3.14968
DCST1 DC-STAMP domain containing 1 -3.14968
LTBP2 latent transforming growth factor beta binding protein 2 -3.14968
AMBP alpha-1-microglobulin/bikunin precursor -3.14968
C17ORF100 chromosome 17 open reading frame 100 -3.14968
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4 -3.14968
TRPM1 transient receptor potential cation channel, subfamily M, member 1 -3.14968
PIH1D2 PIH1 domain containing 2 -3.14968
PDZD9 PDZ domain containing 9 -3.14968
ADAP1 ArfGAP with dual PH domains 1 -3.14968
SYTL5 synaptotagmin-like 5 -3.14968
SDS serine dehydratase -3.14968
PCDHAC1 protocadherin alpha subfamily C, 1 -3.14968
LMO1 LIM domain only 1 (rhombotin 1) -3.14968
PNMA8B PNMA family member 8B -3.14968
PCDHA13 protocadherin alpha 13 -3.14968
ALX3 ALX homeobox 3 -3.14968
MSC musculin -3.14968
ZNF835 zinc finger protein 835 -3.14968
TMPRSS4 transmembrane protease, serine 4 -3.14968
ODAD1 outer dynein arm docking complex subunit 1 -3.14968
SUSD2 sushi domain containing 2 -3.14968
FDXACB1 ferredoxin-fold anticodon binding domain containing 1 -3.14968
TAC1 tachykinin, precursor 1 -3.10167
CDNF cerebral dopamine neurotrophic factor -3.01309
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 -2.95948
DLL3 delta-like 3 (Drosophila) -2.87448
NTF3 neurotrophin 3 -2.8506
CEP76 centrosomal protein 76kDa -2.75096
PITPNM3 PITPNM family member 3 -2.68344
ELP5 elongator acetyltransferase complex subunit 5 -2.67831
LAMP1 lysosomal-associated membrane protein 1 -2.65987
PIGV phosphatidylinositol glycan anchor biosynthesis, class V -2.6498
DONSON downstream neighbor of SON -2.54813
ENSA endosulfine alpha -2.54267
WRNIP1 Werner helicase interacting protein 1 -2.54165
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide -2.51876
TTC3 tetratricopeptide repeat domain 3 -2.51876
GRM1 glutamate receptor, metabotropic 1 -2.47698
SPN sialophorin -2.46003
HARS1 histidyl-tRNA synthetase 1 -2.44984
CMC1 C-x(9)-C motif containing 1 -2.44448
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha -2.43787
STK3 serine/threonine kinase 3 -2.43787
TMEM196 transmembrane protein 196 -2.43787
C5ORF58 chromosome 5 open reading frame 58 -2.43787
STS steroid sulfatase (microsomal), isozyme S -2.43787
PCDHGA6 protocadherin gamma subfamily A, 6 -2.43787
TUBA8 tubulin, alpha 8 -2.43787
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) -2.43787
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 -2.43787
DNAJC30 DnaJ (Hsp40) homolog, subfamily C, member 30 -2.43487
DERL1 derlin 1 -2.43142
NONO non-POU domain containing, octamer-binding -2.43142
FADS2 fatty acid desaturase 2 -2.42347
SLC38A5 solute carrier family 38, member 5 -2.37794
ZNF571 zinc finger protein 571 -2.37409
STX12 syntaxin 12 -2.36533
CSNK2B casein kinase 2, beta polypeptide -2.33053
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa -2.31888
TRPC4 transient receptor potential cation channel, subfamily C, member 4 -2.29319
FAM32A family with sequence similarity 32, member A -2.28839
GALNTL6 polypeptide N-acetylgalactosaminyltransferase-like 6 -2.28628
SIAE sialic acid acetylesterase -2.28628
ZNF672 zinc finger protein 672 -2.28628
JAKMIP1 janus kinase and microtubule interacting protein 1 -2.28628
NUDT17 nudix (nucleoside diphosphate linked moiety X)-type motif 17 -2.26842
EMILIN3 elastin microfibril interfacer 3 -2.26842
ZNF300 zinc finger protein 300 -2.26749
BTBD8 BTB (POZ) domain containing 8 -2.26576
MRPL49 mitochondrial ribosomal protein L49 -2.22963
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa -2.22819
MID1IP1 MID1 interacting protein 1 -2.21352
HMOX2 heme oxygenase 2 -2.20834
CD109 CD109 molecule -2.20573
BRCA1 breast cancer 1, early onset -2.197
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -2.17916
AJAP1 adherens junctions associated protein 1 -2.12286
RAB33B RAB33B, member RAS oncogene family -2.12077
CUEDC1 CUE domain containing 1 -2.11617
OSGEP O-sialoglycoprotein endopeptidase -2.11572
HAS2 hyaluronan synthase 2 -2.10909
DPP10 dipeptidyl-peptidase 10 (non-functional) -2.10344
RCN2 reticulocalbin 2, EF-hand calcium binding domain -2.07748
ACTN2 actinin, alpha 2 -2.06593
CCDC146 coiled-coil domain containing 146 -2.05759
CTR9 CTR9, Paf1/RNA polymerase II complex component -2.04925
NUMB numb homolog (Drosophila) -2.04564
LRRIQ1 leucine-rich repeats and IQ motif containing 1 -2.04318
NF1 neurofibromin 1 -2.04315
MANSC4 MANSC domain containing 4 -2.04315
NCMAP noncompact myelin associated protein -2.04315
LDHAL6A lactate dehydrogenase A-like 6A -2.04315
EMILIN1 elastin microfibril interfacer 1 -2.04315
IFT70B intraflagellar transport 70B -2.04315
LRRC28 leucine rich repeat containing 28 -2.03889
SDC1 syndecan 1 -2.0362
ZEB1 zinc finger E-box binding homeobox 1 -2.03341
JDP2 Jun dimerization protein 2 -2.02437
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae) -2.0239
KIFC2 kinesin family member C2 -2.00162