| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | nuclear receptor subfamily 3, group C, member 2|This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] (NCBI Entrez Gene Database, 4306) |
| External Link | https://ncbi.nlm.nih.gov/gene/4306 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the NR3C2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CA2 | carbonic anhydrase II | 0.0174835 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0143433 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0101377 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.00942717 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.0091894 |
| TPBG | trophoblast glycoprotein | 0.00916117 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.00906253 |
| CNTN1 | contactin 1 | 0.0088172 |
| FOXF1 | forkhead box F1 | 0.00872905 |
| S100A7 | S100 calcium binding protein A7 | 0.00844614 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.00835493 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.00825741 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.00815016 |
| TFRC | transferrin receptor | 0.00801644 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.00801495 |
| MDFIC | MyoD family inhibitor domain containing | 0.00772525 |
| S100A10 | S100 calcium binding protein A10 | 0.00766513 |
| CLDND1 | claudin domain containing 1 | 0.00763526 |
| ACKR3 | atypical chemokine receptor 3 | 0.00762888 |
| AHCYL1 | adenosylhomocysteinase-like 1 | 0.00754532 |
| GNAS | GNAS complex locus | 0.00749636 |
| ABLIM1 | actin binding LIM protein 1 | 0.00731407 |
| EREG | epiregulin | 0.00722861 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00713963 |
| S100A9 | S100 calcium binding protein A9 | 0.00712864 |
| LOX | lysyl oxidase | 0.00711481 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0070708 |
| PSMA1 | proteasome (prosome, macropain) subunit, alpha type, 1 | 0.00705438 |
| SET | SET nuclear proto-oncogene | 0.00705345 |
| SCARB2 | scavenger receptor class B, member 2 | 0.00703809 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.00702501 |
| ANXA1 | annexin A1 | 0.0070212 |
| BTG3 | BTG family, member 3 | 0.00700797 |
| BMP4 | bone morphogenetic protein 4 | 0.00700396 |
| AK4 | adenylate kinase 4 | 0.00699141 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) | 0.00695304 |
| CBX1 | chromobox homolog 1 | 0.0069425 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.00692074 |
| AHNAK | AHNAK nucleoprotein | 0.00690315 |
| PNN | pinin, desmosome associated protein | 0.00681693 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | 0.00676328 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.00676286 |
| RIDA | reactive intermediate imine deaminase A homolog | 0.00673001 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | 0.00671917 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0066256 |
| PPA1 | pyrophosphatase (inorganic) 1 | 0.0065941 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.00655784 |
| RGCC | regulator of cell cycle | 0.00650776 |
| CANX | calnexin | 0.00649954 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.00649928 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | 0.00649375 |
| COL4A5 | collagen, type IV, alpha 5 | 0.00648841 |
| TFDP1 | transcription factor Dp-1 | 0.00644322 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 0.00642955 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0064273 |
| MT1E | metallothionein 1E | 0.00631861 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.00630612 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.00626004 |
| SST | somatostatin | 0.00625382 |
| MXI1 | MAX interactor 1, dimerization protein | 0.00625005 |
| DHFR | dihydrofolate reductase | 0.00623778 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.00622284 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.00620897 |
| TMEM176B | transmembrane protein 176B | 0.00619117 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 0.00618707 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.00615598 |
| SELENBP1 | selenium binding protein 1 | 0.00613763 |
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 0.00610866 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.00610179 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00609988 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.00605286 |
| HNMT | histamine N-methyltransferase | 0.00605254 |
| PCLAF | PCNA clamp associated factor | 0.00604772 |
| LMNB1 | lamin B1 | 0.00604076 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.00597635 |
| CLIC5 | chloride intracellular channel 5 | 0.00597384 |
| EXOC5 | exocyst complex component 5 | 0.00592744 |
| FKBP5 | FK506 binding protein 5 | 0.00591864 |
| GLO1 | glyoxalase I | 0.00590669 |
| CLU | clusterin | 0.0058809 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.00585899 |
| CELSR2 | cadherin, EGF LAG seven-pass G-type receptor 2 | 0.00585426 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.00585391 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.0058438 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | 0.00583743 |
| TNC | tenascin C | 0.00581719 |
| BEX1 | brain expressed, X-linked 1 | 0.00581341 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.00576631 |
| TSPAN3 | tetraspanin 3 | 0.00576579 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.00576527 |
| GLUL | glutamate-ammonia ligase | 0.00573254 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.00571862 |
| APOA1 | apolipoprotein A-I | 0.00568691 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.00568666 |
| RDX | radixin | 0.00567346 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00567224 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00566725 |
| APOC3 | apolipoprotein C-III | 0.00566561 |
| EZR | ezrin | 0.00561821 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | 0.00560023 |
| TUBB6 | tubulin, beta 6 class V | 0.00559296 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.00558018 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.00557673 |
| GLUD2 | glutamate dehydrogenase 2 | 0.00556555 |
| COL3A1 | collagen, type III, alpha 1 | 0.00556448 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.00551041 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00550411 |
| HSPE1 | heat shock 10kDa protein 1 | 0.0055038 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.00549894 |
| CCL14 | chemokine (C-C motif) ligand 14 | 0.00546516 |
| PLPBP | pyridoxal phosphate binding protein | 0.00545651 |
| MYO1C | myosin IC | 0.00545028 |
| PLCG1 | phospholipase C, gamma 1 | 0.0054472 |
| COL5A1 | collagen, type V, alpha 1 | 0.00543358 |
| PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | 0.00541367 |
| MSX1 | msh homeobox 1 | 0.00541261 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.00540111 |
| MYOF | myoferlin | 0.00537732 |
| TMEM176A | transmembrane protein 176A | 0.00537412 |
| FERMT2 | fermitin family member 2 | 0.00537152 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.00535883 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | 0.00532437 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00532415 |
| NARS2 | asparaginyl-tRNA synthetase 2, mitochondrial (putative) | 0.00531437 |
| PAXBP1 | PAX3 and PAX7 binding protein 1 | 0.00531382 |
| LOXL2 | lysyl oxidase-like 2 | 0.00530349 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.00529188 |
| PSRC1 | proline/serine-rich coiled-coil 1 | 0.00527134 |
| FZD5 | frizzled class receptor 5 | 0.00526633 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.00526254 |
| TMEM14A | transmembrane protein 14A | 0.00525759 |
| TCERG1 | transcription elongation regulator 1 | 0.00524165 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 0.0052413 |
| TYMS | thymidylate synthetase | 0.00523197 |
| ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide | 0.0052254 |
| CHN1 | chimerin 1 | 0.00522461 |
| MAIP1 | matrix AAA peptidase interacting protein 1 | 0.00521817 |
| WLS | wntless Wnt ligand secretion mediator | 0.00521297 |
| UBXN4 | UBX domain protein 4 | 0.00520891 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | 0.00520214 |
| FZD6 | frizzled class receptor 6 | 0.00519661 |
| IGSF3 | immunoglobulin superfamily, member 3 | 0.00519051 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.00517754 |
| CDK2 | cyclin-dependent kinase 2 | 0.00517235 |
| CCNL2 | cyclin L2 | 0.00517154 |
| EMC2 | ER membrane protein complex subunit 2 | 0.00516241 |
| HAT1 | histone acetyltransferase 1 | 0.00514409 |
| SLC38A2 | solute carrier family 38, member 2 | 0.00513833 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 0.00512835 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.00509461 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.00508468 |
| SPON1 | spondin 1, extracellular matrix protein | 0.0050755 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.00507117 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00506671 |
| GANAB | glucosidase, alpha; neutral AB | 0.00505432 |
| MATR3 | matrin 3 | 0.00505312 |
| SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 | 0.00503378 |
| FNBP4 | formin binding protein 4 | 0.00502435 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.0050131 |
| MT2A | metallothionein 2A | 0.00501258 |
| SATB2 | SATB homeobox 2 | 0.00501019 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.00500738 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | 0.00498053 |
| KPNA3 | karyopherin alpha 3 (importin alpha 4) | 0.00496428 |
| LRRC17 | leucine rich repeat containing 17 | 0.00496392 |
| RBM39 | RNA binding motif protein 39 | 0.00492901 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00491409 |
| HELLS | helicase, lymphoid-specific | 0.00491278 |
| MST1 | macrophage stimulating 1 | 0.00491111 |
| ACADM | acyl-CoA dehydrogenase, C-4 to C-12 straight chain | 0.00490611 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.00488022 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0048798 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) | 0.00487969 |
| SLC35E2B | solute carrier family 35, member E2B | 0.00486742 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 0.00486221 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 0.00486072 |
| TXN | thioredoxin | 0.00485917 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 0.00485669 |
| BCL6 | B-cell CLL/lymphoma 6 | 0.00485598 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | 0.00485108 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | 0.00483014 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | 0.00481697 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.00480682 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.00480458 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.0047954 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.00477994 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 | 0.00477175 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.00476824 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 | 0.00476542 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.00476191 |
| ENY2 | enhancer of yellow 2 homolog (Drosophila) | 0.00475256 |
| METTL3 | methyltransferase like 3 | 0.00474434 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 0.00473963 |
| CCND1 | cyclin D1 | 0.00473715 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.00473526 |
| PRDX6 | peroxiredoxin 6 | 0.00473404 |
| SLC1A2 | solute carrier family 1 (glial high affinity glutamate transporter), member 2 | 0.00472832 |
| ARMT1 | acidic residue methyltransferase 1 | 0.00472418 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00472392 |
| MAGEA3 | melanoma antigen family A3 | 0.004702 |
| EPHB2 | EPH receptor B2 | 0.00468078 |
| NDFIP1 | Nedd4 family interacting protein 1 | 0.00466436 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.00466193 |
| ELANE | elastase, neutrophil expressed | 0.00466191 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.00465836 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.00465153 |
| EDN3 | endothelin 3 | 0.00465065 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.00464718 |
| APOB | apolipoprotein B | 0.00464495 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | 0.00464155 |
| ASPH | aspartate beta-hydroxylase | 0.00463899 |
| GTF2I | general transcription factor IIi | 0.00462738 |
| MCL1 | myeloid cell leukemia 1 | 0.00461548 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | 0.00459757 |
| CAPRIN1 | cell cycle associated protein 1 | 0.00458999 |
| PRKRA | protein kinase, interferon-inducible double stranded RNA dependent activator | 0.00458287 |
| PRELID3B | PRELI domain containing 3B | 0.00458219 |
| MYO1B | myosin IB | 0.00457787 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 | 0.00456948 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.00454992 |
| CNN3 | calponin 3, acidic | 0.00453678 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.00453541 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | 0.00453267 |
| NAV2 | neuron navigator 2 | 0.00453119 |
| SMC3 | structural maintenance of chromosomes 3 | 0.00452976 |
| PITX3 | paired-like homeodomain 3 | 0.0045289 |
| SYBU | syntabulin (syntaxin-interacting) | 0.00452447 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.00451161 |
| ETNPPL | ethanolamine-phosphate phospho-lyase | 0.00451154 |
| RHOA | ras homolog family member A | 0.00450683 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | 0.00449382 |
| SEPHS1 | selenophosphate synthetase 1 | 0.00448888 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | 0.00448673 |
| MAB21L2 | mab-21-like 2 (C. elegans) | 0.00448185 |
| MECOM | MDS1 and EVI1 complex locus | 0.00447735 |
| PMP22 | peripheral myelin protein 22 | 0.00447414 |
| STOM | stomatin | 0.00447038 |
| CDC42 | cell division cycle 42 | 0.00446721 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.00446657 |
| NEMP1 | nuclear envelope integral membrane protein 1 | 0.00446569 |
| TCF21 | transcription factor 21 | 0.00446307 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00445725 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00442846 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.00442704 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.00442471 |
| ANOS1 | anosmin 1 | 0.00441973 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00439841 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.00439725 |
| MPO | myeloperoxidase | 0.00438262 |
| SRSF6 | serine/arginine-rich splicing factor 6 | 0.00437795 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MMP7 | matrix metallopeptidase 7 | -0.0146883 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | -0.014278 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.014271 |
| AGR2 | anterior gradient 2 | -0.0136348 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.0127634 |
| LTF | lactotransferrin | -0.012678 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.0117191 |
| S100P | S100 calcium binding protein P | -0.0116194 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0111713 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.0107547 |
| WDR7 | WD repeat domain 7 | -0.010706 |
| PROM1 | prominin 1 | -0.0106477 |
| KRT19 | keratin 19, type I | -0.0102519 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00977289 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00961381 |
| LBH | limb bud and heart development | -0.0095796 |
| CYBA | cytochrome b-245, alpha polypeptide | -0.00897947 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.00880052 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.00864344 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.00860633 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.00853368 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.00850139 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00843719 |
| TFF1 | trefoil factor 1 | -0.00843151 |
| GPX3 | glutathione peroxidase 3 | -0.00842651 |
| KRT14 | keratin 14, type I | -0.00837152 |
| APOD | apolipoprotein D | -0.00836467 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.00830252 |
| STK26 | serine/threonine protein kinase 26 | -0.00828397 |
| TESC | tescalcin | -0.0082444 |
| MAGED1 | melanoma antigen family D1 | -0.00807456 |
| NAPA | N-ethylmaleimide-sensitive factor attachment protein, alpha | -0.00804018 |
| HIST1H2BK | histone cluster 1, H2bk | -0.00793383 |
| TSPAN8 | tetraspanin 8 | -0.00780885 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | -0.0077911 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -0.00776661 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00767948 |
| RBM47 | RNA binding motif protein 47 | -0.00761787 |
| HOXC6 | homeobox C6 | -0.00758852 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.00750309 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00742955 |
| MX1 | MX dynamin-like GTPase 1 | -0.00741525 |
| PIP | prolactin-induced protein | -0.00724102 |
| TTC39A | tetratricopeptide repeat domain 39A | -0.00722351 |
| SPON2 | spondin 2, extracellular matrix protein | -0.0072131 |
| TSPAN13 | tetraspanin 13 | -0.00717157 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | -0.00713239 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.00711407 |
| GALC | galactosylceramidase | -0.00711057 |
| PRKCZ | protein kinase C, zeta | -0.00702982 |
| SLC44A4 | solute carrier family 44, member 4 | -0.00682927 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00682246 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | -0.00677535 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.00677251 |
| CNPY3 | canopy FGF signaling regulator 3 | -0.00676655 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.00674791 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00667796 |
| VPS4B | vacuolar protein sorting 4 homolog B (S. cerevisiae) | -0.00666913 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.00657741 |
| C9ORF16 | chromosome 9 open reading frame 16 | -0.00655591 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.00655107 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.00653248 |
| KRT15 | keratin 15, type I | -0.00648783 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00646534 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | -0.00643961 |
| KRT7 | keratin 7, type II | -0.00643857 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.00642777 |
| CRYAB | crystallin, alpha B | -0.00640346 |
| MCOLN1 | mucolipin 1 | -0.00639565 |
| ICAM2 | intercellular adhesion molecule 2 | -0.006387 |
| KYNU | kynureninase | -0.00634908 |
| MGP | matrix Gla protein | -0.00629743 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0062846 |
| NPTX2 | neuronal pentraxin II | -0.00623394 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | -0.00617403 |
| RBPMS | RNA binding protein with multiple splicing | -0.00616633 |
| IPO13 | importin 13 | -0.00615549 |
| CTSK | cathepsin K | -0.00613309 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | -0.00612671 |
| CSTA | cystatin A (stefin A) | -0.00609986 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | -0.00609147 |
| LCN2 | lipocalin 2 | -0.00606163 |
| BAD | BCL2-associated agonist of cell death | -0.00604831 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | -0.00602542 |
| CTSW | cathepsin W | -0.00602209 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -0.00600156 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00597805 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.00597424 |
| NR0B1 | nuclear receptor subfamily 0, group B, member 1 | -0.00597196 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.00592833 |
| ATG101 | autophagy related 101 | -0.00592613 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.00592161 |
| ATP6V0D1 | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 | -0.00590655 |
| RNPS1 | RNA binding protein S1, serine-rich domain | -0.00587865 |
| GSPT2 | G1 to S phase transition 2 | -0.0058547 |
| RNF144A | ring finger protein 144A | -0.00584472 |
| HMOX1 | heme oxygenase 1 | -0.00584266 |
| PNKP | polynucleotide kinase 3'-phosphatase | -0.00580812 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00580284 |
| SERPINB7 | serpin peptidase inhibitor, clade B (ovalbumin), member 7 | -0.00579334 |
| S100A11 | S100 calcium binding protein A11 | -0.00576914 |
| PTN | pleiotrophin | -0.00576812 |
| RABAC1 | Rab acceptor 1 (prenylated) | -0.00576333 |
| GSTT1 | glutathione S-transferase theta 1 | -0.00573248 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.0057044 |
| CCN2 | cellular communication network factor 2 | -0.00561833 |
| WDR45 | WD repeat domain 45 | -0.00561004 |
| VNN1 | vanin 1 | -0.00559712 |
| TXLNA | taxilin alpha | -0.0055912 |
| TAGLN | transgelin | -0.00558371 |
| ING3 | inhibitor of growth family, member 3 | -0.00558346 |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | -0.00557477 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.00556475 |
| MXRA7 | matrix-remodelling associated 7 | -0.00556184 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | -0.00555909 |
| DUSP5 | dual specificity phosphatase 5 | -0.00555663 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) | -0.00553168 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 | -0.00547854 |
| NRBF2 | nuclear receptor binding factor 2 | -0.0054691 |
| HOXC10 | homeobox C10 | -0.00544322 |
| SFRP4 | secreted frizzled-related protein 4 | -0.0054372 |
| MIOS | missing oocyte, meiosis regulator, homolog (Drosophila) | -0.00542126 |
| TSPO | translocator protein (18kDa) | -0.00541337 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00538977 |
| VWA5A | von Willebrand factor A domain containing 5A | -0.0053895 |
| ZNHIT1 | zinc finger, HIT-type containing 1 | -0.00538581 |
| DCLK1 | doublecortin-like kinase 1 | -0.00535916 |
| IL6R | interleukin 6 receptor | -0.00533878 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | -0.00533275 |
| HDAC9 | histone deacetylase 9 | -0.0053271 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.00531804 |
| CD1E | CD1e molecule | -0.0053083 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | -0.00528438 |
| ETNK1 | ethanolamine kinase 1 | -0.00528024 |
| ARMCX6 | armadillo repeat containing, X-linked 6 | -0.00527254 |
| DCN | decorin | -0.00526283 |
| MZB1 | marginal zone B and B1 cell-specific protein | -0.00525194 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.00522106 |
| NID2 | nidogen 2 (osteonidogen) | -0.00521163 |
| FAM53B | family with sequence similarity 53, member B | -0.00519696 |
| UPP1 | uridine phosphorylase 1 | -0.00518573 |
| AGTR1 | angiotensin II receptor, type 1 | -0.00516272 |
| PRELP | proline/arginine-rich end leucine-rich repeat protein | -0.00515517 |
| MMP9 | matrix metallopeptidase 9 | -0.00513249 |
| TIMM13 | translocase of inner mitochondrial membrane 13 homolog (yeast) | -0.00512217 |
| NEU1 | sialidase 1 (lysosomal sialidase) | -0.00512129 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | -0.00511415 |
| HIST1H2BD | histone cluster 1, H2bd | -0.00510035 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.00509907 |
| CTSE | cathepsin E | -0.00509792 |
| EFHD2 | EF-hand domain family, member D2 | -0.00509034 |
| CLDN4 | claudin 4 | -0.00508914 |
| DEF8 | differentially expressed in FDCP 8 homolog (mouse) | -0.00507046 |
| C3ORF52 | chromosome 3 open reading frame 52 | -0.00506631 |
| SCG5 | secretogranin V | -0.00505035 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | -0.00503857 |
| UBXN6 | UBX domain protein 6 | -0.00501962 |
| ORC5 | origin recognition complex, subunit 5 | -0.00501534 |
| CD7 | CD7 molecule | -0.00499293 |
| NOTCH3 | notch 3 | -0.00499175 |
| PYROXD1 | pyridine nucleotide-disulphide oxidoreductase domain 1 | -0.0049903 |
| INAVA | innate immunity activator | -0.00497342 |
| JUNB | jun B proto-oncogene | -0.00497224 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 | -0.00495933 |
| MYO6 | myosin VI | -0.00495193 |
| WDR13 | WD repeat domain 13 | -0.00494966 |
| EGR1 | early growth response 1 | -0.00493998 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00493913 |
| SPAG1 | sperm associated antigen 1 | -0.00493502 |
| CCDC28B | coiled-coil domain containing 28B | -0.00492569 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.00492279 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.00492145 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.0049097 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | -0.00490724 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00490407 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.00490166 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 | -0.00488842 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) | -0.00488758 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 | -0.00488503 |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa | -0.00487199 |
| MAP2K2 | mitogen-activated protein kinase kinase 2 | -0.00487114 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 | -0.00486409 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | -0.00485252 |
| STAP2 | signal transducing adaptor family member 2 | -0.00485175 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) | -0.00483597 |
| TGFA | transforming growth factor, alpha | -0.00483406 |
| CD320 | CD320 molecule | -0.00481777 |
| PTK2B | protein tyrosine kinase 2 beta | -0.00479912 |
| COCH | cochlin | -0.00478145 |
| PLXNC1 | plexin C1 | -0.00477637 |
| PERP | PERP, TP53 apoptosis effector | -0.00477506 |
| MRPL23 | mitochondrial ribosomal protein L23 | -0.00474987 |
| TFPT | TCF3 (E2A) fusion partner (in childhood Leukemia) | -0.00474525 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.00474111 |
| CHMP4A | charged multivesicular body protein 4A | -0.00474045 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00471881 |
| ERCC1 | excision repair cross-complementation group 1 | -0.00471737 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | -0.0047094 |
| POU2AF1 | POU class 2 associating factor 1 | -0.00470395 |
| GPX2 | glutathione peroxidase 2 | -0.00468143 |
| FA2H | fatty acid 2-hydroxylase | -0.00465877 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.00465365 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00464693 |
| GCHFR | GTP cyclohydrolase I feedback regulator | -0.00463293 |
| DGKZ | diacylglycerol kinase, zeta | -0.00463108 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | -0.00462675 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00461701 |
| PLPP2 | phospholipid phosphatase 2 | -0.00461468 |
| MSMB | microseminoprotein, beta- | -0.00459905 |
| KIAA0930 | KIAA0930 | -0.00459406 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -0.0045844 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.00457551 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.00457235 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.00457157 |
| TSPYL5 | TSPY-like 5 | -0.00456546 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 | -0.00455546 |
| CCDC69 | coiled-coil domain containing 69 | -0.00455149 |
| GLB1L2 | galactosidase, beta 1-like 2 | -0.00454929 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.00454279 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | -0.00452298 |
| CCDC22 | coiled-coil domain containing 22 | -0.00452185 |
| ZNF329 | zinc finger protein 329 | -0.00451511 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.00451461 |
| MAP9 | microtubule-associated protein 9 | -0.00450437 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 | -0.00450124 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | -0.00449924 |
| RGS2 | regulator of G-protein signaling 2 | -0.00448272 |
| BAX | BCL2-associated X protein | -0.0044752 |
| NKX3-1 | NK3 homeobox 1 | -0.00447238 |
| BUD31 | BUD31 homolog (S. cerevisiae) | -0.00445838 |
| MXD4 | MAX dimerization protein 4 | -0.00444947 |
| RETREG1 | reticulophagy regulator 1 | -0.00444542 |
| VGLL4 | vestigial-like family member 4 | -0.0044431 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.0044423 |
| LAMC2 | laminin, gamma 2 | -0.00443176 |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) | -0.00441446 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.00440617 |
| RRAS | related RAS viral (r-ras) oncogene homolog | -0.00439938 |
| COBL | cordon-bleu WH2 repeat protein | -0.00438462 |
| RTN1 | reticulon 1 | -0.00438227 |
| C8ORF4 | chromosome 8 open reading frame 4 | -0.00438165 |
| COMP | cartilage oligomeric matrix protein | -0.0043666 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | -0.00436246 |
| CTSD | cathepsin D | -0.00435766 |
| YARS1 | tyrosyl-tRNA synthetase 1 | -0.00435663 |
| LSP1 | lymphocyte-specific protein 1 | -0.00434995 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 | -0.00433762 |
| FBLN5 | fibulin 5 | -0.00433432 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00433103 |
