NR4A2 Gene Set

Dataset ChEA Transcription Factor Targets
Category genomics
Type transcription factor
Description nuclear receptor subfamily 4, group A, member 2|This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4929)
External Link http://www.ncbi.nlm.nih.gov/gene/4929
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Genes

167 target genes of the NR4A2 transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.

Symbol Name
ACSL3 acyl-CoA synthetase long-chain family member 3
ADAM12 ADAM metallopeptidase domain 12
ADGRB3 adhesion G protein-coupled receptor B3
ADGRD1 adhesion G protein-coupled receptor D1
ADGRF2 adhesion G protein-coupled receptor F2
ADGRL3 adhesion G protein-coupled receptor L3
AMDHD2 amidohydrolase domain containing 2
ANLN anillin, actin binding protein
ARHGAP22 Rho GTPase activating protein 22
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARID5B AT rich interactive domain 5B (MRF1-like)
ARL9 ADP-ribosylation factor-like 9
ARPP21 cAMP-regulated phosphoprotein, 21kDa
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
ATF5 activating transcription factor 5
ATN1 atrophin 1
ATP13A2 ATPase type 13A2
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
AURKC aurora kinase C
BCCIP BRCA2 and CDKN1A interacting protein
BOLA3 bolA family member 3
BRD2 bromodomain containing 2
BRSK1 BR serine/threonine kinase 1
CARTPT CART prepropeptide
CBX7 chromobox homolog 7
CCDC7 coiled-coil domain containing 7
CCL21 chemokine (C-C motif) ligand 21
CD200R1L CD200 receptor 1-like
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CELF2 CUGBP, Elav-like family member 2
CHM choroideremia (Rab escort protein 1)
CHN1 chimerin 1
CPE carboxypeptidase E
CXXC4 CXXC finger protein 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DCXR dicarbonyl/L-xylulose reductase
DKKL1 dickkopf-like 1
DPP6 dipeptidyl-peptidase 6
DPYS dihydropyrimidinase
DYNLRB2 dynein, light chain, roadblock-type 2
DYNLT1 dynein, light chain, Tctex-type 1
EFCAB5 EF-hand calcium binding domain 5
ELAVL4 ELAV like neuron-specific RNA binding protein 4
ELOVL6 ELOVL fatty acid elongase 6
FAM156A family with sequence similarity 156, member A
FBF1 Fas (TNFRSF6) binding factor 1
FBXO36 F-box protein 36
FDXR ferredoxin reductase
FGD5 FYVE, RhoGEF and PH domain containing 5
FGF12 fibroblast growth factor 12
FOXRED1 FAD-dependent oxidoreductase domain containing 1
FSHB follicle stimulating hormone, beta polypeptide
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GKAP1 G kinase anchoring protein 1
GPC2 glypican 2
GPM6A glycoprotein M6A
GRB10 growth factor receptor-bound protein 10
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D
HAPLN4 hyaluronan and proteoglycan link protein 4
HRH4 histamine receptor H4
IFT20 intraflagellar transport 20
IL4I1 interleukin 4 induced 1
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KARS lysyl-tRNA synthetase
KCTD15 potassium channel tetramerization domain containing 15
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KLF7 Kruppel-like factor 7 (ubiquitous)
KLHL26 kelch-like family member 26
LHX5 LIM homeobox 5
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LMTK3 lemur tyrosine kinase 3
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase
MAGEA2 melanoma antigen family A2
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAP2 microtubule-associated protein 2
MARCKS myristoylated alanine-rich protein kinase C substrate
MAST1 microtubule associated serine/threonine kinase 1
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MRGPRX3 MAS-related GPR, member X3
MRPS18B mitochondrial ribosomal protein S18B
MTUS1 microtubule associated tumor suppressor 1
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYT1L myelin transcription factor 1-like
NEU2 sialidase 2 (cytosolic sialidase)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NLRP4 NLR family, pyrin domain containing 4
NUP62 nucleoporin 62kDa
OR52K2 olfactory receptor, family 52, subfamily K, member 2
OR6X1 olfactory receptor, family 6, subfamily X, member 1
PDLIM5 PDZ and LIM domain 5
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PHB prohibitin
PHLDB2 pleckstrin homology-like domain, family B, member 2
PLD3 phospholipase D family, member 3
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PON1 paraoxonase 1
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPP1R10 protein phosphatase 1, regulatory subunit 10
PRCP prolylcarboxypeptidase (angiotensinase C)
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PTPRU protein tyrosine phosphatase, receptor type, U
PXDN peroxidasin
RAB3C RAB3C, member RAS oncogene family
RBM15 RNA binding motif protein 15
REEP3 receptor accessory protein 3
REXO2 RNA exonuclease 2
RGS2 regulator of G-protein signaling 2
RPL26 ribosomal protein L26
RTN1 reticulon 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SASH3 SAM and SH3 domain containing 3
SCML2 sex comb on midleg-like 2 (Drosophila)
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIRT2 sirtuin 2
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein
SNAP25 synaptosomal-associated protein, 25kDa
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
SRP9 signal recognition particle 9kDa
SRPR signal recognition particle receptor (docking protein)
SRSF3 serine/arginine-rich splicing factor 3
SSBP3 single stranded DNA binding protein 3
STAG3 stromal antigen 3
STMN4 stathmin-like 4
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TEAD2 TEA domain family member 2
TMED6 transmembrane emp24 protein transport domain containing 6
TMEM98 transmembrane protein 98
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNRC18 trinucleotide repeat containing 18
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRIB2 tribbles pseudokinase 2
TRIP12 thyroid hormone receptor interactor 12
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TSC22D1 TSC22 domain family, member 1
TSN translin
TUBA4A tubulin, alpha 4a
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb
UBAP2L ubiquitin associated protein 2-like
UBASH3A ubiquitin associated and SH3 domain containing A
UBQLN2 ubiquilin 2
UBTF upstream binding transcription factor, RNA polymerase I
UGT1A5 UDP glucuronosyltransferase 1 family, polypeptide A5
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9
UPB1 ureidopropionase, beta
UROS uroporphyrinogen III synthase
WDR13 WD repeat domain 13
WDR45B WD repeat domain 45B
WSB2 WD repeat and SOCS box containing 2
ZBTB18 zinc finger and BTB domain containing 18
ZBTB38 zinc finger and BTB domain containing 38
ZFP37 ZFP37 zinc finger protein
ZMYM2 zinc finger, MYM-type 2
ZNF146 zinc finger protein 146
ZNF260 zinc finger protein 260
ZNF383 zinc finger protein 383
ZNF566 zinc finger protein 566
ZNF580 zinc finger protein 580
ZNF585A zinc finger protein 585A
ZNF608 zinc finger protein 608
ZWINT ZW10 interacting kinetochore protein