| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | nuclear receptor subfamily 4, group A, member 2|This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4929) |
| External Link | https://ncbi.nlm.nih.gov/gene/4929 |
| Similar Terms | |
| Downloads & Tools |
497 genes differentially expressed following the NR4A2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.0200079 |
| PLK2 | polo-like kinase 2 | 0.0181943 |
| MAP7 | microtubule-associated protein 7 | 0.0180513 |
| HTRA1 | HtrA serine peptidase 1 | 0.0176507 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.016855 |
| CFB | complement factor B | 0.0164669 |
| IFI44L | interferon-induced protein 44-like | 0.0163832 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.0157716 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.0148668 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0148517 |
| CTSD | cathepsin D | 0.014777 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.01465 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0146241 |
| IPO13 | importin 13 | 0.0144912 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0144747 |
| TPSAB1 | tryptase alpha/beta 1 | 0.0141734 |
| GNAS | GNAS complex locus | 0.0139311 |
| PTK2B | protein tyrosine kinase 2 beta | 0.0136478 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.0134552 |
| WDR7 | WD repeat domain 7 | 0.0134214 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.0133259 |
| APOD | apolipoprotein D | 0.0126689 |
| GPNMB | glycoprotein (transmembrane) nmb | 0.0125786 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0125526 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0125226 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.0124256 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.012375 |
| MX1 | MX dynamin-like GTPase 1 | 0.0122191 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.0121587 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0121468 |
| KRT7 | keratin 7, type II | 0.0121122 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.0118906 |
| KAZN | kazrin, periplakin interacting protein | 0.0118606 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0113693 |
| COG7 | component of oligomeric golgi complex 7 | 0.0113059 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.0112968 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | 0.0111536 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.0111238 |
| H1-2 | H1.2 linker histone, cluster member | 0.011102 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0110918 |
| ZNF91 | zinc finger protein 91 | 0.0110839 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0110293 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | 0.0109314 |
| FOLR1 | folate receptor 1 (adult) | 0.0108252 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.0106741 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.010618 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.0105351 |
| PDGFC | platelet derived growth factor C | 0.0105152 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.0104803 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0104444 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0103445 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 | 0.0103439 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | 0.010342 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.0103391 |
| MMP7 | matrix metallopeptidase 7 | 0.0102809 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0101873 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0101849 |
| DEPTOR | DEP domain containing MTOR-interacting protein | 0.0101721 |
| CLU | clusterin | 0.00998722 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00996783 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00996617 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.00983192 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00968595 |
| NCDN | neurochondrin | 0.00960928 |
| CRYAB | crystallin, alpha B | 0.00960716 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00958626 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.0095322 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0094993 |
| SLC44A4 | solute carrier family 44, member 4 | 0.00948055 |
| RND3 | Rho family GTPase 3 | 0.0094794 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.00945065 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.0094347 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00937161 |
| CD38 | CD38 molecule | 0.00932924 |
| IER5 | immediate early response 5 | 0.00931767 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00923835 |
| CP | ceruloplasmin (ferroxidase) | 0.00922759 |
| IRF7 | interferon regulatory factor 7 | 0.00920124 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 0.00917418 |
| HBD | hemoglobin, delta | 0.00911096 |
| PLD3 | phospholipase D family, member 3 | 0.00907107 |
| GPX3 | glutathione peroxidase 3 | 0.00901893 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.00901818 |
| SQSTM1 | sequestosome 1 | 0.00900066 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.00896962 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00895466 |
| FKBP11 | FK506 binding protein 11, 19 kDa | 0.00890261 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00886695 |
| ADIRF | adipogenesis regulatory factor | 0.00880785 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | 0.00875268 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.00872074 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00870682 |
| CLGN | calmegin | 0.00864892 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | 0.00863073 |
| PXDC1 | PX domain containing 1 | 0.00860623 |
| TLE5 | TLE family member 5, transcriptional modulator | 0.00858352 |
| BEX4 | brain expressed, X-linked 4 | 0.00856074 |
| EFNB2 | ephrin-B2 | 0.00855271 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.00852671 |
| DCN | decorin | 0.00850352 |
| MT1E | metallothionein 1E | 0.00849407 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0084938 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | 0.00848638 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0084799 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00846385 |
| CCND3 | cyclin D3 | 0.00842934 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00842188 |
| NPY | neuropeptide Y | 0.00842181 |
| GGT1 | gamma-glutamyltransferase 1 | 0.00841346 |
| CLDN3 | claudin 3 | 0.00839598 |
| WASL | Wiskott-Aldrich syndrome-like | 0.00835891 |
| NKX3-1 | NK3 homeobox 1 | 0.00829228 |
| PMP22 | peripheral myelin protein 22 | 0.0082912 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00828916 |
| CLDN4 | claudin 4 | 0.00827565 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.00827535 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | 0.0082451 |
| TUFT1 | tuftelin 1 | 0.0082279 |
| CTSK | cathepsin K | 0.00822279 |
| IL7R | interleukin 7 receptor | 0.00822171 |
| RBPMS | RNA binding protein with multiple splicing | 0.0082208 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.00820146 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00818455 |
| KIF5B | kinesin family member 5B | 0.00818286 |
| IFI44 | interferon-induced protein 44 | 0.00815402 |
| KYNU | kynureninase | 0.0081457 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.00813622 |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 | 0.00813033 |
| SNAI2 | snail family zinc finger 2 | 0.00812901 |
| ST18 | suppression of tumorigenicity 18, zinc finger | 0.00812736 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.0080954 |
| NEU1 | sialidase 1 (lysosomal sialidase) | 0.00806457 |
| S100A8 | S100 calcium binding protein A8 | 0.00805488 |
| DUSP5 | dual specificity phosphatase 5 | 0.00799031 |
| SIK1 | salt-inducible kinase 1 | 0.00795055 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.00794883 |
| HIST1H2BK | histone cluster 1, H2bk | 0.00794578 |
| EMP3 | epithelial membrane protein 3 | 0.00794421 |
| ZNF264 | zinc finger protein 264 | 0.00794086 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | 0.00792283 |
| PIP | prolactin-induced protein | 0.00789944 |
| VEGFC | vascular endothelial growth factor C | 0.00788896 |
| PRSS8 | protease, serine, 8 | 0.00788373 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.00788361 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.00787003 |
| LMNA | lamin A/C | 0.00778379 |
| MSLN | mesothelin | 0.00776825 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.00776648 |
| TRIB2 | tribbles pseudokinase 2 | 0.00775497 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.00774905 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.00772348 |
| MANSC1 | MANSC domain containing 1 | 0.00769891 |
| FRMD4B | FERM domain containing 4B | 0.00767481 |
| ZBED2 | zinc finger, BED-type containing 2 | 0.00767294 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00765671 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.0076379 |
| PERP | PERP, TP53 apoptosis effector | 0.0076064 |
| LCN2 | lipocalin 2 | 0.00760244 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.00758902 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | 0.00758728 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.00753729 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | 0.00752765 |
| CD9 | CD9 molecule | 0.00749864 |
| HIST1H2AE | histone cluster 1, H2ae | 0.00747874 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.00746566 |
| RPS27L | ribosomal protein S27-like | 0.0074437 |
| AUTS2 | autism susceptibility candidate 2 | 0.00743532 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | 0.0074327 |
| HIST2H2BE | histone cluster 2, H2be | 0.00742832 |
| IRF9 | interferon regulatory factor 9 | 0.00740262 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 | 0.00740192 |
| SYNGR3 | synaptogyrin 3 | 0.00739783 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.00739638 |
| METRN | meteorin, glial cell differentiation regulator | 0.00739576 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.007383 |
| EHF | ets homologous factor | 0.00737423 |
| IRS2 | insulin receptor substrate 2 | 0.00733416 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00731903 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | 0.00731716 |
| HDAC9 | histone deacetylase 9 | 0.00730041 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 | 0.00729957 |
| FAM46C | family with sequence similarity 46, member C | 0.00728929 |
| SCG5 | secretogranin V | 0.00728284 |
| C2 | complement component 2 | 0.0072766 |
| TRIP6 | thyroid hormone receptor interactor 6 | 0.00727622 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.00727257 |
| TXLNA | taxilin alpha | 0.00726928 |
| RGS16 | regulator of G-protein signaling 16 | 0.00724636 |
| PNMA8A | PNMA family member 8A | 0.00724385 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.00721749 |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa | 0.00721381 |
| KRT14 | keratin 14, type I | 0.00720697 |
| MEIS2 | Meis homeobox 2 | 0.00719061 |
| DCLK1 | doublecortin-like kinase 1 | 0.00718923 |
| KLF10 | Kruppel-like factor 10 | 0.00714373 |
| TRIM22 | tripartite motif containing 22 | 0.00713785 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | 0.00712146 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.0070877 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | 0.00708044 |
| ZNF512B | zinc finger protein 512B | 0.0070657 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | 0.00703259 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.00702723 |
| TOX3 | TOX high mobility group box family member 3 | 0.00701622 |
| PKM | pyruvate kinase, muscle | 0.00700585 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | 0.00699368 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | 0.00698641 |
| NAPA | N-ethylmaleimide-sensitive factor attachment protein, alpha | 0.00696612 |
| GAS1 | growth arrest-specific 1 | 0.00695125 |
| HMOX1 | heme oxygenase 1 | 0.00694412 |
| FN1 | fibronectin 1 | 0.00694321 |
| MX2 | MX dynamin-like GTPase 2 | 0.00691895 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00686394 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.00685668 |
| AREG | amphiregulin | 0.00684727 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.00684169 |
| ECM1 | extracellular matrix protein 1 | 0.00683655 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.00682881 |
| SMAD7 | SMAD family member 7 | 0.00681649 |
| MT1M | metallothionein 1M | 0.00680939 |
| PPL | periplakin | 0.00677635 |
| ITGAV | integrin, alpha V | 0.00676671 |
| APOC1 | apolipoprotein C-I | 0.00676138 |
| TLK2 | tousled-like kinase 2 | 0.00670302 |
| RNF19B | ring finger protein 19B | 0.00668825 |
| MT1G | metallothionein 1G | 0.00666334 |
| VLDLR | very low density lipoprotein receptor | 0.00664985 |
| ING3 | inhibitor of growth family, member 3 | 0.0066384 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.00663825 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | 0.0066095 |
| SYT1 | synaptotagmin I | 0.00660864 |
| TRIM29 | tripartite motif containing 29 | 0.00660261 |
| NXN | nucleoredoxin | 0.00658735 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | 0.00658068 |
| XAF1 | XIAP associated factor 1 | 0.00657554 |
| PEG10 | paternally expressed 10 | 0.00657271 |
| BCL7B | B-cell CLL/lymphoma 7B | 0.00656205 |
| QDPR | quinoid dihydropteridine reductase | 0.00656151 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | 0.00655318 |
| RTP4 | receptor (chemosensory) transporter protein 4 | 0.00654542 |
| LBH | limb bud and heart development | 0.0065374 |
| CDR2L | cerebellar degeneration-related protein 2-like | 0.00650683 |
| TRAPPC6A | trafficking protein particle complex 6A | 0.00650211 |
| PIGR | polymeric immunoglobulin receptor | 0.00649794 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.00646534 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | 0.0064593 |
| OTUD4 | OTU deubiquitinase 4 | 0.00640927 |
| STK26 | serine/threonine protein kinase 26 | 0.0064054 |
| ITGB4 | integrin, beta 4 | 0.00634906 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -0.0147766 |
| LY6D | lymphocyte antigen 6 complex, locus D | -0.0132081 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.0125083 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.012101 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | -0.0120402 |
| SIRT3 | sirtuin 3 | -0.0116626 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0109839 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.0106337 |
| POSTN | periostin, osteoblast specific factor | -0.0105011 |
| MSX1 | msh homeobox 1 | -0.0104413 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0104033 |
| GPC3 | glypican 3 | -0.0104018 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) | -0.0103848 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -0.0103103 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.010236 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0101824 |
| CDCA4 | cell division cycle associated 4 | -0.00969602 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00965089 |
| PSAT1 | phosphoserine aminotransferase 1 | -0.00950819 |
| IL1R2 | interleukin 1 receptor, type II | -0.00913576 |
| HAL | histidine ammonia-lyase | -0.00913295 |
| MAGEA3 | melanoma antigen family A3 | -0.00902193 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | -0.00902171 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -0.00889682 |
| SPC25 | SPC25, NDC80 kinetochore complex component | -0.00888748 |
| MYBPC1 | myosin binding protein C, slow type | -0.00871425 |
| AURKB | aurora kinase B | -0.0086409 |
| OIP5 | Opa interacting protein 5 | -0.00862507 |
| G0S2 | G0/G1 switch 2 | -0.00861646 |
| OLFM1 | olfactomedin 1 | -0.00859107 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | -0.0085739 |
| ACADM | acyl-CoA dehydrogenase, C-4 to C-12 straight chain | -0.00853258 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.00847678 |
| CLDND1 | claudin domain containing 1 | -0.0083889 |
| MATN2 | matrilin 2 | -0.00837169 |
| GSTA1 | glutathione S-transferase alpha 1 | -0.00835196 |
| RUVBL1 | RuvB-like AAA ATPase 1 | -0.00833318 |
| MAGEA12 | melanoma antigen family A12 | -0.00832754 |
| MDM1 | Mdm1 nuclear protein homolog (mouse) | -0.00831295 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.00826533 |
| GOLM1 | golgi membrane protein 1 | -0.00826313 |
| S100A10 | S100 calcium binding protein A10 | -0.00823075 |
| MPO | myeloperoxidase | -0.00822738 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00816845 |
| TGFB3 | transforming growth factor, beta 3 | -0.00815753 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | -0.00814542 |
| MRPL19 | mitochondrial ribosomal protein L19 | -0.00812436 |
| CALCA | calcitonin-related polypeptide alpha | -0.00798433 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00794593 |
| SLURP1 | secreted LY6/PLAUR domain containing 1 | -0.00793259 |
| APOBEC3A | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A | -0.00792333 |
| SET | SET nuclear proto-oncogene | -0.00791507 |
| KRT1 | keratin 1, type II | -0.00790231 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | -0.00788181 |
| EXOC5 | exocyst complex component 5 | -0.00784635 |
| ACOT7 | acyl-CoA thioesterase 7 | -0.00784137 |
| RAD51AP1 | RAD51 associated protein 1 | -0.00778835 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.007778 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00777056 |
| FERMT1 | fermitin family member 1 | -0.00776376 |
| S100A7 | S100 calcium binding protein A7 | -0.00765474 |
| GRB14 | growth factor receptor-bound protein 14 | -0.00765467 |
| TTN | titin | -0.00763123 |
| COL1A2 | collagen, type I, alpha 2 | -0.00760987 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.00760383 |
| PRKCA | protein kinase C, alpha | -0.00758084 |
| MTARC2 | mitochondrial amidoxime reducing component 2 | -0.00756662 |
| PSMA1 | proteasome (prosome, macropain) subunit, alpha type, 1 | -0.00756274 |
| SRSF6 | serine/arginine-rich splicing factor 6 | -0.00754854 |
| PNN | pinin, desmosome associated protein | -0.00751405 |
| ASF1B | anti-silencing function 1B histone chaperone | -0.007473 |
| YEATS4 | YEATS domain containing 4 | -0.0074248 |
| MXI1 | MAX interactor 1, dimerization protein | -0.00741054 |
| BRCA1 | breast cancer 1, early onset | -0.00740149 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | -0.00739354 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.0073729 |
| TFDP1 | transcription factor Dp-1 | -0.00735385 |
| MKI67 | marker of proliferation Ki-67 | -0.00735285 |
| CDCA3 | cell division cycle associated 3 | -0.00734385 |
| LOR | loricrin | -0.00727218 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.00726469 |
| MBD1 | methyl-CpG binding domain protein 1 | -0.00715832 |
| PRDX2 | peroxiredoxin 2 | -0.00712964 |
| RHOA | ras homolog family member A | -0.00712827 |
| CPOX | coproporphyrinogen oxidase | -0.00712802 |
| TMEM38B | transmembrane protein 38B | -0.007104 |
| DSG1 | desmoglein 1 | -0.0070868 |
| DMD | dystrophin | -0.00707824 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | -0.00707105 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | -0.00705734 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00705696 |
| RNASEH2A | ribonuclease H2, subunit A | -0.00705361 |
| NDC80 | NDC80 kinetochore complex component | -0.00703758 |
| RBBP7 | retinoblastoma binding protein 7 | -0.00701781 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00701453 |
| FZD5 | frizzled class receptor 5 | -0.00694098 |
| FOXF1 | forkhead box F1 | -0.00691754 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0069151 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | -0.00687287 |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 | -0.00686363 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | -0.00686153 |
| KIF18A | kinesin family member 18A | -0.00684192 |
| CD200 | CD200 molecule | -0.00679273 |
| RWDD3 | RWD domain containing 3 | -0.00677086 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.00676444 |
| PXDN | peroxidasin | -0.00675823 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.00674873 |
| ACYP1 | acylphosphatase 1, erythrocyte (common) type | -0.00673856 |
| GYG2 | glycogenin 2 | -0.0067167 |
| SPAG5 | sperm associated antigen 5 | -0.00671641 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.00671587 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | -0.00671288 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.00670999 |
| CALML4 | calmodulin-like 4 | -0.00669533 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.00669366 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | -0.00669184 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | -0.00668217 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.00666823 |
| S100P | S100 calcium binding protein P | -0.00662916 |
| PTCH1 | patched 1 | -0.00662142 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 | -0.00660755 |
| MGP | matrix Gla protein | -0.00660728 |
| ESD | esterase D | -0.00659434 |
| TRAPPC2 | trafficking protein particle complex 2 | -0.00659196 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.00658255 |
| TFRC | transferrin receptor | -0.00657447 |
| BMP2 | bone morphogenetic protein 2 | -0.00656748 |
| SRSF1 | serine/arginine-rich splicing factor 1 | -0.00656013 |
| IL17RB | interleukin 17 receptor B | -0.00655927 |
| CCNE2 | cyclin E2 | -0.0065392 |
| ZDHHC17 | zinc finger, DHHC-type containing 17 | -0.00651289 |
| RBM39 | RNA binding motif protein 39 | -0.00650954 |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein | -0.00649623 |
| KRT2 | keratin 2, type II | -0.0064947 |
| HOXB7 | homeobox B7 | -0.00645876 |
| CDA | cytidine deaminase | -0.00645236 |
| EZR | ezrin | -0.00644672 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -0.00640767 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | -0.00639163 |
| IRF8 | interferon regulatory factor 8 | -0.00639035 |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | -0.00638095 |
| KIF20A | kinesin family member 20A | -0.00637474 |
| CYP2C18 | cytochrome P450, family 2, subfamily C, polypeptide 18 | -0.00633336 |
| FOXO1 | forkhead box O1 | -0.00632993 |
| GDI2 | GDP dissociation inhibitor 2 | -0.00632813 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.00632691 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | -0.00632361 |
| TIA1 | TIA1 cytotoxic granule-associated RNA binding protein | -0.0063091 |
| PDZK1 | PDZ domain containing 1 | -0.00630212 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.00629306 |
| FABP7 | fatty acid binding protein 7, brain | -0.00626417 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | -0.00625332 |
| NUP85 | nucleoporin 85kDa | -0.00623693 |
| ARL14 | ADP-ribosylation factor-like 14 | -0.00622641 |
| HOXC6 | homeobox C6 | -0.00622524 |
| NUTF2 | nuclear transport factor 2 | -0.00622442 |
| TCEA1 | transcription elongation factor A (SII), 1 | -0.00621264 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.00618807 |
| GEMIN2 | gem (nuclear organelle) associated protein 2 | -0.00618066 |
| PUF60 | poly-U binding splicing factor 60KDa | -0.00616766 |
| TNNC1 | troponin C type 1 (slow) | -0.00615824 |
| SYNM | synemin, intermediate filament protein | -0.00615602 |
| B4GALT6 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 | -0.00615222 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | -0.00614689 |
| FBXO5 | F-box protein 5 | -0.00613795 |
| CCKBR | cholecystokinin B receptor | -0.00613503 |
| GLO1 | glyoxalase I | -0.00612906 |
| CNTN1 | contactin 1 | -0.00612777 |
| EDNRB | endothelin receptor type B | -0.00612416 |
| CALML3 | calmodulin-like 3 | -0.00612327 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.00612292 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0061208 |
| TRH | thyrotropin-releasing hormone | -0.00610928 |
| GSTA4 | glutathione S-transferase alpha 4 | -0.00610513 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | -0.00610307 |
| LMNB1 | lamin B1 | -0.00606711 |
| RHCG | Rh family, C glycoprotein | -0.00606336 |
| PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | -0.00606045 |
| TMEM176B | transmembrane protein 176B | -0.0060517 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.00601667 |
| SDC2 | syndecan 2 | -0.0060159 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | -0.00600217 |
| LIG1 | ligase I, DNA, ATP-dependent | -0.00598371 |
| DICER1 | dicer 1, ribonuclease type III | -0.00597719 |
| MDFIC | MyoD family inhibitor domain containing | -0.00596095 |
| TFF1 | trefoil factor 1 | -0.00595851 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0059562 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00594102 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | -0.00592942 |
| IFT52 | intraflagellar transport 52 | -0.0059208 |
| IDE | insulin-degrading enzyme | -0.00591246 |
| E2F8 | E2F transcription factor 8 | -0.00588828 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 | -0.00588056 |
| SPRR2B | small proline-rich protein 2B | -0.00587324 |
| ARG1 | arginase 1 | -0.00586805 |
| IPO5 | importin 5 | -0.00586645 |
| PLCG1 | phospholipase C, gamma 1 | -0.00586622 |
| PDE6D | phosphodiesterase 6D, cGMP-specific, rod, delta | -0.00586298 |
| TSPAN3 | tetraspanin 3 | -0.0058587 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.00585249 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | -0.00585014 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.00584941 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | -0.00584733 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.00584348 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.00584123 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.00583625 |
| MTMR11 | myotubularin related protein 11 | -0.00582798 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.00581449 |
| MST1 | macrophage stimulating 1 | -0.00580928 |
| PMCH | pro-melanin-concentrating hormone | -0.00579975 |
| FHL1 | four and a half LIM domains 1 | -0.00578844 |
| PCOLCE | procollagen C-endopeptidase enhancer | -0.00578785 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -0.00576979 |
| STX10 | syntaxin 10 | -0.00575906 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | -0.00575896 |
| SORD | sorbitol dehydrogenase | -0.00575649 |
| CHEK1 | checkpoint kinase 1 | -0.00575005 |
| BEX1 | brain expressed, X-linked 1 | -0.00574948 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -0.00574926 |
| NCAPG | non-SMC condensin I complex, subunit G | -0.0057456 |
| HAPLN1 | hyaluronan and proteoglycan link protein 1 | -0.00574196 |
| KLF6 | Kruppel-like factor 6 | -0.00572985 |
| GSTM2 | glutathione S-transferase mu 2 (muscle) | -0.00572884 |
| C11ORF58 | chromosome 11 open reading frame 58 | -0.00572717 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00571192 |
| SLC35E2B | solute carrier family 35, member E2B | -0.00570587 |
| AKTIP | AKT interacting protein | -0.00570135 |
| FABP1 | fatty acid binding protein 1, liver | -0.00569074 |
| POU4F1 | POU class 4 homeobox 1 | -0.00569047 |
| CD93 | CD93 molecule | -0.0056827 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.00568159 |
| PODXL | podocalyxin-like | -0.00568012 |
| ANXA3 | annexin A3 | -0.00566803 |
| GLMN | glomulin, FKBP associated protein | -0.00565677 |
| C4BPB | complement component 4 binding protein, beta | -0.0056483 |
| ZNF516 | zinc finger protein 516 | -0.00564585 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.00564102 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | -0.00563935 |
| VTI1B | vesicle transport through interaction with t-SNAREs 1B | -0.00563817 |
| KIF15 | kinesin family member 15 | -0.00563793 |
| CA2 | carbonic anhydrase II | -0.00563779 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.00563382 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.00562824 |
| INHBB | inhibin, beta B | -0.00562782 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 | -0.00562717 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0056216 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.00561758 |
| TPX2 | TPX2, microtubule-associated | -0.0056101 |
| COL3A1 | collagen, type III, alpha 1 | -0.00560655 |
