NRP1 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description neuropilin 1|This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011] (NCBI Entrez Gene Database, 8829)
External Link http://www.ncbi.nlm.nih.gov/gene/8829
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Genes

104 interacting proteins for NRP1 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AUTS2 autism susceptibility candidate 2
BCAS2 breast carcinoma amplified sequence 2
BCR breakpoint cluster region
BRD2 bromodomain containing 2
C11ORF57 chromosome 11 open reading frame 57
C18ORF25 chromosome 18 open reading frame 25
CCDC59 coiled-coil domain containing 59
CCNL1 cyclin L1
CCNL2 cyclin L2
CDC5L cell division cycle 5-like
CDK11A cyclin-dependent kinase 11A
CDK11B cyclin-dependent kinase 11B
CDK5 cyclin-dependent kinase 5
COIL coilin
CRMP1 collapsin response mediator protein 1
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2A2 casein kinase 2, alpha prime polypeptide
CSNK2B casein kinase 2, beta polypeptide
DCAF7 DDB1 and CUL4 associated factor 7
DEK DEK proto-oncogene
DPYSL2 dihydropyrimidinase-like 2
DPYSL3 dihydropyrimidinase-like 3
DPYSL4 dihydropyrimidinase-like 4
DPYSL5 dihydropyrimidinase-like 5
EFCAB14 EF-hand calcium binding domain 14
EIF3B eukaryotic translation initiation factor 3, subunit B
EIF3J eukaryotic translation initiation factor 3, subunit J
FBRS fibrosin
FBRSL1 fibrosin-like 1
FES FES proto-oncogene, tyrosine kinase
FGF1 fibroblast growth factor 1 (acidic)
FGF2 fibroblast growth factor 2 (basic)
FGF4 fibroblast growth factor 4
FGF7 fibroblast growth factor 7
FGFR1 fibroblast growth factor receptor 1
FLNA filamin A, alpha
FLT1 fms-related tyrosine kinase 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GIPC1 GIPC PDZ domain containing family, member 1
GPATCH2 G patch domain containing 2
GPC4 glypican 4
GSK3B glycogen synthase kinase 3 beta
GTPBP4 GTP binding protein 4
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HAGHL hydroxyacylglutathione hydrolase-like
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIRIP3 HIRA interacting protein 3
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KDR kinase insert domain receptor
KMT2A lysine (K)-specific methyltransferase 2A
L1CAM L1 cell adhesion molecule
LIMK1 LIM domain kinase 1
NKAP NFKB activating protein
NOLC1 nucleolar and coiled-body phosphoprotein 1
NRP2 neuropilin 2
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PCGF3 polycomb group ring finger 3
PCGF5 polycomb group ring finger 5
PDGFB platelet-derived growth factor beta polypeptide
PGF placental growth factor
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PLRG1 pleiotropic regulator 1
PLVAP plasmalemma vesicle associated protein
PLXNA1 plexin A1
PLXNA2 plexin A2
PNN pinin, desmosome associated protein
PRMT1 protein arginine methyltransferase 1
PRPF19 pre-mRNA processing factor 19
PRRC2C proline-rich coiled-coil 2C
RHOA ras homolog family member A
RING1 ring finger protein 1
RNF111 ring finger protein 111
RNF2 ring finger protein 2
RPL27 ribosomal protein L27
RRAS related RAS viral (r-ras) oncogene homolog
RRP1B ribosomal RNA processing 1B
RYBP RING1 and YY1 binding protein
SAP18 Sin3A-associated protein, 18kDa
SAP30BP SAP30 binding protein
SDAD1 SDA1 domain containing 1
SDC2 syndecan 2
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SQSTM1 sequestosome 1
SRRM1 serine/arginine repetitive matrix 1
TCOF1 Treacher Collins-Franceschetti syndrome 1
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
THRAP3 thyroid hormone receptor associated protein 3
UBC ubiquitin C
VEGFA vascular endothelial growth factor A
VEGFB vascular endothelial growth factor B
WDR5 WD repeat domain 5
YAF2 YY1 associated factor 2
ZC3H18 zinc finger CCCH-type containing 18
ZNF687 zinc finger protein 687