NS-398-6892 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the NS-398-6892 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AASS aminoadipate-semialdehyde synthase
AGMAT agmatine ureohydrolase (agmatinase)
AHI1 Abelson helper integration site 1
AKAP7 A kinase (PRKA) anchor protein 7
ARMC6 armadillo repeat containing 6
ATAT1 alpha tubulin acetyltransferase 1
ATXN7L1 ataxin 7-like 1
BMP7 bone morphogenetic protein 7
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CALHM2 calcium homeostasis modulator 2
CD4 CD4 molecule
CDC5L cell division cycle 5-like
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEP85 centrosomal protein 85kDa
CLCN7 chloride channel, voltage-sensitive 7
CREB5 cAMP responsive element binding protein 5
CRYBA2 crystallin, beta A2
CSF1 colony stimulating factor 1 (macrophage)
CXCL5 chemokine (C-X-C motif) ligand 5
DST dystonin
DVL3 dishevelled segment polarity protein 3
ETNK1 ethanolamine kinase 1
GALT galactose-1-phosphate uridylyltransferase
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GK glycerol kinase
GSK3A glycogen synthase kinase 3 alpha
HAP1 huntingtin-associated protein 1
HEG1 heart development protein with EGF-like domains 1
HLA-DMA major histocompatibility complex, class II, DM alpha
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
ICA1 islet cell autoantigen 1, 69kDa
IFI6 interferon, alpha-inducible protein 6
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL11 interleukin 11
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KDM7A lysine (K)-specific demethylase 7A
KIAA0040 KIAA0040
KIAA1107 KIAA1107
KRT17 keratin 17, type I
KYNU kynureninase
LOC730101 uncharacterized LOC730101
LPAR2 lysophosphatidic acid receptor 2
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAP2K7 mitogen-activated protein kinase kinase 7
MFAP3L microfibrillar-associated protein 3-like
MGC12488
MN1 meningioma (disrupted in balanced translocation) 1
MSI1 musashi RNA-binding protein 1
MTM1 myotubularin 1
MUC5B mucin 5B, oligomeric mucus/gel-forming
MX1 MX dynamin-like GTPase 1
NF1 neurofibromin 1
NUDCD3 NudC domain containing 3
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
OPRL1 opiate receptor-like 1
PDE4D phosphodiesterase 4D, cAMP-specific
PER3 period circadian clock 3
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PICK1 protein interacting with PRKCA 1
PIDD1 p53-induced death domain protein 1
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
POMT2 protein-O-mannosyltransferase 2
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
PTPN2 protein tyrosine phosphatase, non-receptor type 2
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RNF126P1 ring finger protein 126 pseudogene 1
RNFT1 ring finger protein, transmembrane 1
RPAIN RPA interacting protein
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEC23A Sec23 homolog A (S. cerevisiae)
SGK2 serum/glucocorticoid regulated kinase 2
SGSM2 small G protein signaling modulator 2
SH2B1 SH2B adaptor protein 1
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLMO1 slowmo homolog 1 (Drosophila)
SNORA21 small nucleolar RNA, H/ACA box 21
STARD5 StAR-related lipid transfer (START) domain containing 5
STAT1 signal transducer and activator of transcription 1, 91kDa
STC1 stanniocalcin 1
TCF3 transcription factor 3
TCTN2 tectonic family member 2
TMEM212 transmembrane protein 212
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRAPPC13 trafficking protein particle complex 13
TRIO trio Rho guanine nucleotide exchange factor
UGT8 UDP glycosyltransferase 8
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VASH1 vasohibin 1
WAS Wiskott-Aldrich syndrome
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
YY2 YY2 transcription factor
ZNF280B zinc finger protein 280B
ZNF518A zinc finger protein 518A
ZNF75D zinc finger protein 75D

decreased expression

Symbol Name
ADAM29 ADAM metallopeptidase domain 29
ADGRE2 adhesion G protein-coupled receptor E2
AHSP alpha hemoglobin stabilizing protein
AIM2 absent in melanoma 2
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AMH anti-Mullerian hormone
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APH1A APH1A gamma secretase subunit
APOH apolipoprotein H (beta-2-glycoprotein I)
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ARSA arylsulfatase A
AURKC aurora kinase C
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BATF3 basic leucine zipper transcription factor, ATF-like 3
BOLA1 bolA family member 1
C11ORF68 chromosome 11 open reading frame 68
C17ORF80 chromosome 17 open reading frame 80
C3 complement component 3
CCDC132 coiled-coil domain containing 132
CCDC71 coiled-coil domain containing 71
CCR9 chemokine (C-C motif) receptor 9
CEL carboxyl ester lipase
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CPNE7 copine VII
DLK2 delta-like 2 homolog (Drosophila)
DTX2 deltex 2, E3 ubiquitin ligase
EGFL7 EGF-like-domain, multiple 7
EXOC6B exocyst complex component 6B
EYA4 EYA transcriptional coactivator and phosphatase 4
F13A1 coagulation factor XIII, A1 polypeptide
F3 coagulation factor III (thromboplastin, tissue factor)
FBXO22 F-box protein 22
FKRP fukutin related protein
FRS2 fibroblast growth factor receptor substrate 2
GALK1 galactokinase 1
GGTLC1 gamma-glutamyltransferase light chain 1
HDAC11 histone deacetylase 11
HIST1H3B histone cluster 1, H3b
HMOX1 heme oxygenase 1
KCNK5 potassium channel, two pore domain subfamily K, member 5
KIFC1 kinesin family member C1
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MBD5 methyl-CpG binding domain protein 5
MMP13 matrix metallopeptidase 13
MMP9 matrix metallopeptidase 9
MMRN2 multimerin 2
MOXD1 monooxygenase, DBH-like 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTERF4 mitochondrial transcription termination factor 4
MYL9 myosin, light chain 9, regulatory
NABP1 nucleic acid binding protein 1
NACAD NAC alpha domain containing
NPIPB15 nuclear pore complex interacting protein family, member B15
NSUN6 NOP2/Sun domain family, member 6
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PARP3 poly (ADP-ribose) polymerase family, member 3
PARP6 poly (ADP-ribose) polymerase family, member 6
PDE12 phosphodiesterase 12
PGLYRP4 peptidoglycan recognition protein 4
PHEX phosphate regulating endopeptidase homolog, X-linked
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PIP prolactin-induced protein
PLAG1 pleiomorphic adenoma gene 1
PODXL2 podocalyxin-like 2
PRAMEF11 PRAME family member 11
PSKH1 protein serine kinase H1
RHCG Rh family, C glycoprotein
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
SAMD9 sterile alpha motif domain containing 9
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
STARD3 StAR-related lipid transfer (START) domain containing 3
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
THBS3 thrombospondin 3
TICAM1 toll-like receptor adaptor molecule 1
TM6SF1 transmembrane 6 superfamily member 1
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TXNL4B thioredoxin-like 4B
UNC119 unc-119 homolog (C. elegans)
UPK3B uroplakin 3B
USP21 ubiquitin specific peptidase 21
UTF1 undifferentiated embryonic cell transcription factor 1
WDR25 WD repeat domain 25
WT1-AS WT1 antisense RNA
YPEL1 yippee-like 1 (Drosophila)
ZFP30 ZFP30 zinc finger protein
ZNF253 zinc finger protein 253
ZNF408 zinc finger protein 408
ZNF41 zinc finger protein 41
ZNF446 zinc finger protein 446
ZNF574 zinc finger protein 574
ZNF671 zinc finger protein 671
ZNF702P zinc finger protein 702, pseudogene
ZNF74 zinc finger protein 74
ZNF76 zinc finger protein 76
ZNF862 zinc finger protein 862