NS-398-6897 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the NS-398-6897 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ALMS1 Alstrom syndrome protein 1
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
APLP2 amyloid beta (A4) precursor-like protein 2
ARHGAP35 Rho GTPase activating protein 35
ATP7A ATPase, Cu++ transporting, alpha polypeptide
BAGE B melanoma antigen
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BPHL biphenyl hydrolase-like (serine hydrolase)
BST2 bone marrow stromal cell antigen 2
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C11ORF80 chromosome 11 open reading frame 80
C14ORF93 chromosome 14 open reading frame 93
C17ORF80 chromosome 17 open reading frame 80
C2CD2 C2 calcium-dependent domain containing 2
CACYBP calcyclin binding protein
CCDC69 coiled-coil domain containing 69
CCHCR1 coiled-coil alpha-helical rod protein 1
CD44 CD44 molecule (Indian blood group)
CDK19 cyclin-dependent kinase 19
CENPI centromere protein I
CHMP1B charged multivesicular body protein 1B
CLASP2 cytoplasmic linker associated protein 2
COPA coatomer protein complex, subunit alpha
COPS8 COP9 signalosome subunit 8
DCAF15 DDB1 and CUL4 associated factor 15
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DXO decapping exoribonuclease
EPHB2 EPH receptor B2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERO1L ERO1-like (S. cerevisiae)
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GOSR2 golgi SNAP receptor complex member 2
GTDC1 glycosyltransferase-like domain containing 1
GTF2I general transcription factor IIi
HIST1H1E histone cluster 1, H1e
HOXA4 homeobox A4
IFITM1 interferon induced transmembrane protein 1
IFT38 intraflagellar transport 38
ING1 inhibitor of growth family, member 1
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
ITPK1 inositol-tetrakisphosphate 1-kinase
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KIAA0895 KIAA0895
LOC647070 uncharacterized LOC647070
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LYPD1 LY6/PLAUR domain containing 1
MAP2K3 mitogen-activated protein kinase kinase 3
MAPK11 mitogen-activated protein kinase 11
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCM3AP minichromosome maintenance complex component 3 associated protein
METTL8 methyltransferase like 8
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MIIP migration and invasion inhibitory protein
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MMP17 matrix metallopeptidase 17 (membrane-inserted)
NEK9 NIMA-related kinase 9
NFYA nuclear transcription factor Y, alpha
NR2F6 nuclear receptor subfamily 2, group F, member 6
NUMA1 nuclear mitotic apparatus protein 1
NUP62CL nucleoporin 62kDa C-terminal like
PACS1 phosphofurin acidic cluster sorting protein 1
PAX5 paired box 5
PELI1 pellino E3 ubiquitin protein ligase 1
PPP1R7 protein phosphatase 1, regulatory subunit 7
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RECQL5 RecQ protein-like 5
REST RE1-silencing transcription factor
RGS12 regulator of G-protein signaling 12
RPAP1 RNA polymerase II associated protein 1
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RPS3A ribosomal protein S3A
SCAPER S-phase cyclin A-associated protein in the ER
SCN1B sodium channel, voltage gated, type I beta subunit
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SOCS2 suppressor of cytokine signaling 2
SPIDR scaffolding protein involved in DNA repair
ST5 suppression of tumorigenicity 5
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STAT5B signal transducer and activator of transcription 5B
STK16 serine/threonine kinase 16
STK24 serine/threonine kinase 24
TBC1D4 TBC1 domain family, member 4
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TMED2 transmembrane emp24 domain trafficking protein 2
TRAIP TRAF interacting protein
TUBGCP5 tubulin, gamma complex associated protein 5
TWF2 twinfilin actin binding protein 2
WDR59 WD repeat domain 59
WWOX WW domain containing oxidoreductase
ZER1 zyg-11 related, cell cycle regulator
ZNF34 zinc finger protein 34

decreased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANKHD1 ankyrin repeat and KH domain containing 1
ARRB1 arrestin, beta 1
ATG2A autophagy related 2A
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
AXIN1 axin 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C1ORF54 chromosome 1 open reading frame 54
C2ORF44 chromosome 2 open reading frame 44
CLGN calmegin
CNR2 cannabinoid receptor 2 (macrophage)
CRELD1 cysteine-rich with EGF-like domains 1
CRLF1 cytokine receptor-like factor 1
CRYBB2P1 crystallin, beta B2 pseudogene 1
CXORF56 chromosome X open reading frame 56
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DBF4B DBF4 zinc finger B
DHODH dihydroorotate dehydrogenase (quinone)
DMTN dematin actin binding protein
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EPHB6 EPH receptor B6
FAM131A family with sequence similarity 131, member A
FBXO46 F-box protein 46
FRMPD1 FERM and PDZ domain containing 1
FRS2 fibroblast growth factor receptor substrate 2
GADD45G growth arrest and DNA-damage-inducible, gamma
GBP2 guanylate binding protein 2, interferon-inducible
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR19 G protein-coupled receptor 19
GPR68 G protein-coupled receptor 68
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIST1H2AG histone cluster 1, H2ag
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXB2 homeobox B2
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HYAL1 hyaluronoglucosaminidase 1
IP6K1 inositol hexakisphosphate kinase 1
IQSEC2 IQ motif and Sec7 domain 2
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KDM5C lysine (K)-specific demethylase 5C
KLF13 Kruppel-like factor 13
KLHL25 kelch-like family member 25
KLHL28 kelch-like family member 28
KREMEN2 kringle containing transmembrane protein 2
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MGC12488
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MVP major vault protein
MYO19 myosin XIX
NKRF NFKB repressing factor
NLRX1 NLR family member X1
OGFRL1 opioid growth factor receptor-like 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PADI1 peptidyl arginine deiminase, type I
PARP16 poly (ADP-ribose) polymerase family, member 16
PGP phosphoglycolate phosphatase
PLCD1 phospholipase C, delta 1
PORCN porcupine homolog (Drosophila)
PPT2 palmitoyl-protein thioesterase 2
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PTDSS2 phosphatidylserine synthase 2
PTPRM protein tyrosine phosphatase, receptor type, M
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RFTN1 raftlin, lipid raft linker 1
RIN2 Ras and Rab interactor 2
RNF121 ring finger protein 121
SCNN1B sodium channel, non voltage gated 1 beta subunit
SIX1 SIX homeobox 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SMYD5 SMYD family member 5
SND1-IT1 SND1 intronic transcript 1
SPAG7 sperm associated antigen 7
SPON2 spondin 2, extracellular matrix protein
SRD5A3 steroid 5 alpha-reductase 3
STRA6 stimulated by retinoic acid 6
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
TCTA T-cell leukemia translocation altered
TGFB3 transforming growth factor, beta 3
TMEM53 transmembrane protein 53
TRAF2 TNF receptor-associated factor 2
TRIOBP TRIO and F-actin binding protein
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TRPM8 transient receptor potential cation channel, subfamily M, member 8
ULBP2 UL16 binding protein 2
USP19 ubiquitin specific peptidase 19
VIPR1 vasoactive intestinal peptide receptor 1
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
XAB2 XPA binding protein 2
ZBTB22 zinc finger and BTB domain containing 22
ZDHHC14 zinc finger, DHHC-type containing 14
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF675 zinc finger protein 675
ZNF862 zinc finger protein 862