| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | neurotrophic tyrosine kinase, receptor, type 2|This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] (NCBI Entrez Gene Database, 4915) |
| External Link | https://ncbi.nlm.nih.gov/gene/4915 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the NTRK2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AQP3 | aquaporin 3 (Gill blood group) | 0.0131479 |
| TXLNA | taxilin alpha | 0.0105148 |
| TSPAN8 | tetraspanin 8 | 0.0104372 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0102806 |
| SFN | stratifin | 0.00994726 |
| CCND1 | cyclin D1 | 0.00994514 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.00949676 |
| INSR | insulin receptor | 0.00918868 |
| TFF3 | trefoil factor 3 (intestinal) | 0.00889076 |
| DIPK1A | divergent protein kinase domain 1A | 0.0085906 |
| LRP4 | low density lipoprotein receptor-related protein 4 | 0.00841162 |
| MYO1D | myosin ID | 0.00830629 |
| GNAS | GNAS complex locus | 0.0082018 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00797333 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00793961 |
| S100A2 | S100 calcium binding protein A2 | 0.00783594 |
| TFF1 | trefoil factor 1 | 0.00774906 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.00763444 |
| GOLGA8A | golgin A8 family, member A | 0.00759594 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | 0.00751047 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | 0.00748386 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | 0.0074282 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.00739774 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | 0.00736028 |
| NPEPL1 | aminopeptidase-like 1 | 0.00716611 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 0.00715178 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00705343 |
| YBX3 | Y box binding protein 3 | 0.00683007 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0068292 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific | 0.00681443 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 0.00681164 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.00679242 |
| CPE | carboxypeptidase E | 0.0067546 |
| PLXNA1 | plexin A1 | 0.00673643 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.00671187 |
| RRBP1 | ribosome binding protein 1 | 0.00671186 |
| CIT | citron rho-interacting serine/threonine kinase | 0.0066296 |
| TPD52 | tumor protein D52 | 0.00660795 |
| JPT2 | Jupiter microtubule associated homolog 2 | 0.00660752 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.00642001 |
| DHCR24 | 24-dehydrocholesterol reductase | 0.00641233 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00636523 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.00633897 |
| MELK | maternal embryonic leucine zipper kinase | 0.0063208 |
| MARCKSL1 | MARCKS-like 1 | 0.00627883 |
| RNF43 | ring finger protein 43 | 0.00626707 |
| DSC2 | desmocollin 2 | 0.00623029 |
| DACH1 | dachshund family transcription factor 1 | 0.00623011 |
| GPX2 | glutathione peroxidase 2 | 0.00616177 |
| HEPH | hephaestin | 0.00612233 |
| ABHD2 | abhydrolase domain containing 2 | 0.0061122 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | 0.00609667 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.00606263 |
| KCTD14 | potassium channel tetramerization domain containing 14 | 0.00598329 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.00597685 |
| SPATA20 | spermatogenesis associated 20 | 0.00596465 |
| DMBT1 | deleted in malignant brain tumors 1 | 0.00595181 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | 0.00594795 |
| MX1 | MX dynamin-like GTPase 1 | 0.00593871 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.00591395 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00591203 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | 0.00591126 |
| SMTN | smoothelin | 0.00588438 |
| ESRP2 | epithelial splicing regulatory protein 2 | 0.00587346 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | 0.00586747 |
| A2M | alpha-2-macroglobulin | 0.00586345 |
| COPS7A | COP9 signalosome subunit 7A | 0.00585873 |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | 0.00582477 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.00582334 |
| SDC1 | syndecan 1 | 0.00582118 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.00580199 |
| CD320 | CD320 molecule | 0.00579019 |
| NAV2 | neuron navigator 2 | 0.00578144 |
| TBX3 | T-box 3 | 0.00577744 |
| FABP1 | fatty acid binding protein 1, liver | 0.00576886 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 | 0.00576655 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | 0.00574939 |
| CDC25B | cell division cycle 25B | 0.00572903 |
| MMP3 | matrix metallopeptidase 3 | 0.00572707 |
| NCOR2 | nuclear receptor corepressor 2 | 0.00571117 |
| RGS5 | regulator of G-protein signaling 5 | 0.00571076 |
| NOP2 | NOP2 nucleolar protein | 0.00569772 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.00567384 |
| PTCH1 | patched 1 | 0.00565022 |
| HDAC1 | histone deacetylase 1 | 0.00563369 |
| TGM2 | transglutaminase 2 | 0.00560734 |
| COL4A2 | collagen, type IV, alpha 2 | 0.00560259 |
| BRD4 | bromodomain containing 4 | 0.00560194 |
| PCDH17 | protocadherin 17 | 0.00559942 |
| SPEN | spen family transcriptional repressor | 0.00557729 |
| FOXA1 | forkhead box A1 | 0.00557374 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.00557275 |
| NONO | non-POU domain containing, octamer-binding | 0.00554937 |
| ATP10B | ATPase, class V, type 10B | 0.00554415 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.00554342 |
| HELZ | helicase with zinc finger | 0.00552501 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00552195 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 | 0.00548631 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.00547509 |
| FOXF1 | forkhead box F1 | 0.00542996 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.00542843 |
| SH3BP4 | SH3-domain binding protein 4 | 0.00542696 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.00542258 |
| SFTPA2 | surfactant protein A2 | 0.00540524 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.00538484 |
| SIRT3 | sirtuin 3 | 0.00537275 |
| MYH11 | myosin, heavy chain 11, smooth muscle | 0.00531457 |
| RBM26 | RNA binding motif protein 26 | 0.00531252 |
| WDR6 | WD repeat domain 6 | 0.00531247 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.00530254 |
| FOXM1 | forkhead box M1 | 0.00530161 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00530003 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.00529473 |
| EPHB2 | EPH receptor B2 | 0.00527965 |
| NR1I2 | nuclear receptor subfamily 1, group I, member 2 | 0.00527856 |
| PCDH9 | protocadherin 9 | 0.00524456 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.00524013 |
| VWF | von Willebrand factor | 0.00523946 |
| CCDC22 | coiled-coil domain containing 22 | 0.00522713 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.00521762 |
| MAGEA3 | melanoma antigen family A3 | 0.00521429 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.00518508 |
| FKBP9 | FK506 binding protein 9, 63 kDa | 0.00518276 |
| PHF10 | PHD finger protein 10 | 0.00517137 |
| GNMT | glycine N-methyltransferase | 0.00516529 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | 0.0051642 |
| DEFA6 | defensin, alpha 6, Paneth cell-specific | 0.00515859 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | 0.00515767 |
| SS18L1 | synovial sarcoma translocation gene on chromosome 18-like 1 | 0.00514383 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.00514317 |
| ANKRD10 | ankyrin repeat domain 10 | 0.00511864 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | 0.0051151 |
| CLCA1 | chloride channel accessory 1 | 0.00509373 |
| KRT6A | keratin 6A, type II | 0.00508949 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | 0.00507332 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | 0.00506817 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | 0.00506508 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.00505522 |
| CCNF | cyclin F | 0.00505261 |
| CCND2 | cyclin D2 | 0.00503943 |
| SPRR1B | small proline-rich protein 1B | 0.00502481 |
| ELAC2 | elaC ribonuclease Z 2 | 0.00502371 |
| SFTPC | surfactant protein C | 0.005005 |
| PRKCA | protein kinase C, alpha | 0.00500178 |
| NELL2 | NEL-like 2 (chicken) | 0.00498024 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit | 0.00497735 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.00497612 |
| PRAME | preferentially expressed antigen in melanoma | 0.00497235 |
| TMEM204 | transmembrane protein 204 | 0.00495005 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.00494447 |
| CNTNAP2 | contactin associated protein-like 2 | 0.00493693 |
| KIF5B | kinesin family member 5B | 0.00492999 |
| PHB2 | prohibitin 2 | 0.00492666 |
| ARG2 | arginase 2 | 0.00492646 |
| VCP | valosin containing protein | 0.00491219 |
| CRTC3 | CREB regulated transcription coactivator 3 | 0.00488342 |
| CALML3 | calmodulin-like 3 | 0.00487889 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | 0.00487165 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.00487037 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00485273 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 | 0.00484657 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.00483788 |
| EDNRA | endothelin receptor type A | 0.00483769 |
| GAA | glucosidase, alpha; acid | 0.00482519 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 | 0.00481545 |
| HEATR1 | HEAT repeat containing 1 | 0.00481501 |
| TIMELESS | timeless circadian clock | 0.00481321 |
| RBM6 | RNA binding motif protein 6 | 0.00480525 |
| ENO3 | enolase 3 (beta, muscle) | 0.00477832 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00477424 |
| RAPSN | receptor-associated protein of the synapse | 0.00476087 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.00475205 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0047469 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00474582 |
| TRIM44 | tripartite motif containing 44 | 0.00473736 |
| HMGB3 | high mobility group box 3 | 0.00472951 |
| CYP39A1 | cytochrome P450, family 39, subfamily A, polypeptide 1 | 0.00470434 |
| CST1 | cystatin SN | 0.00470319 |
| SLC25A1 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | 0.00469992 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.00469457 |
| KPNB1 | karyopherin (importin) beta 1 | 0.00469323 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.00468588 |
| CBX1 | chromobox homolog 1 | 0.00467746 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0046759 |
| DSG1 | desmoglein 1 | 0.00466756 |
| GOT2 | glutamic-oxaloacetic transaminase 2, mitochondrial | 0.00466689 |
| IRS2 | insulin receptor substrate 2 | 0.00466143 |
| HDAC6 | histone deacetylase 6 | 0.00466004 |
| TUG1 | taurine up-regulated 1 (non-protein coding) | 0.00464221 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.004641 |
| KCTD3 | potassium channel tetramerization domain containing 3 | 0.00463229 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 | 0.0046276 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00462409 |
| COL16A1 | collagen, type XVI, alpha 1 | 0.00461878 |
| C19ORF54 | chromosome 19 open reading frame 54 | 0.00461695 |
| LMNB2 | lamin B2 | 0.00461633 |
| COL4A6 | collagen, type IV, alpha 6 | 0.00461282 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.00460623 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.00460397 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | 0.00459895 |
| GUSB | glucuronidase, beta | 0.00459792 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 0.00458945 |
| GPSM2 | G-protein signaling modulator 2 | 0.00457745 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00457719 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.00456983 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | 0.00456403 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 | 0.00456288 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0045589 |
| LONP2 | lon peptidase 2, peroxisomal | 0.00455747 |
| PNN | pinin, desmosome associated protein | 0.00454904 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | 0.0045481 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.00454572 |
| CSAD | cysteine sulfinic acid decarboxylase | 0.00454303 |
| USP11 | ubiquitin specific peptidase 11 | 0.00453904 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 | 0.00453626 |
| AUTS2 | autism susceptibility candidate 2 | 0.00453547 |
| ADAR | adenosine deaminase, RNA-specific | 0.00453463 |
| SORD | sorbitol dehydrogenase | 0.00452404 |
| MCM3 | minichromosome maintenance complex component 3 | 0.00451809 |
| FAAH | fatty acid amide hydrolase | 0.00451619 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.00450606 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.00450528 |
| SYT17 | synaptotagmin XVII | 0.00450114 |
| REG1A | regenerating islet-derived 1 alpha | 0.00449834 |
| MAGED2 | melanoma antigen family D2 | 0.00448981 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.00448938 |
| PER3 | period circadian clock 3 | 0.00448756 |
| EPHB3 | EPH receptor B3 | 0.00448631 |
| GOLGB1 | golgin B1 | 0.00447416 |
| TRAF5 | TNF receptor-associated factor 5 | 0.00447238 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.00446794 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.00446212 |
| ESYT1 | extended synaptotagmin-like protein 1 | 0.004457 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.00445383 |
| H1-0 | H1.0 linker histone | 0.00445153 |
| ABHD6 | abhydrolase domain containing 6 | 0.00444949 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) | 0.00444568 |
| PNOC | prepronociceptin | 0.00444361 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00443645 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | 0.00442839 |
| CERS6 | ceramide synthase 6 | 0.00442731 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | 0.00441823 |
| PWWP3A | PWWP domain containing 3A, DNA repair factor | 0.0044162 |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 0.00441085 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.00441034 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | 0.00440634 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.00439904 |
| KIF2C | kinesin family member 2C | 0.00439487 |
| PKP1 | plakophilin 1 | 0.00439476 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.00439023 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LTF | lactotransferrin | -0.0194043 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0168411 |
| S100A9 | S100 calcium binding protein A9 | -0.015634 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.0151127 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.0123884 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.0119393 |
| LCN2 | lipocalin 2 | -0.0117922 |
| S100A8 | S100 calcium binding protein A8 | -0.0115894 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0115833 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0111206 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.0110475 |
| H1-2 | H1.2 linker histone, cluster member | -0.0110071 |
| ANXA1 | annexin A1 | -0.0110044 |
| CRYAB | crystallin, alpha B | -0.0103565 |
| C10ORF10 | chromosome 10 open reading frame 10 | -0.00989425 |
| BEX4 | brain expressed, X-linked 4 | -0.00983905 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00983684 |
| CYBB | cytochrome b-245, beta polypeptide | -0.00952597 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.0094245 |
| HIST1H2AC | histone cluster 1, H2ac | -0.00939041 |
| CLU | clusterin | -0.00937221 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | -0.00934003 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.00920724 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00891084 |
| MT1E | metallothionein 1E | -0.0088154 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00872397 |
| CD59 | CD59 molecule, complement regulatory protein | -0.00859859 |
| MT1F | metallothionein 1F | -0.00852541 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -0.00848318 |
| PITX3 | paired-like homeodomain 3 | -0.00846996 |
| MT1X | metallothionein 1X | -0.00843008 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.00833279 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00831136 |
| CTSD | cathepsin D | -0.00822505 |
| GSTO1 | glutathione S-transferase omega 1 | -0.00814442 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | -0.00804996 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00799858 |
| PLIN1 | perilipin 1 | -0.00798539 |
| NRCAM | neuronal cell adhesion molecule | -0.00784697 |
| ATF3 | activating transcription factor 3 | -0.00772187 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | -0.00772059 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | -0.00770728 |
| MT1G | metallothionein 1G | -0.00766394 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.00764519 |
| AK4 | adenylate kinase 4 | -0.00763581 |
| HDAC9 | histone deacetylase 9 | -0.00759623 |
| EVI2A | ecotropic viral integration site 2A | -0.00759057 |
| TPD52L1 | tumor protein D52-like 1 | -0.0075417 |
| DCN | decorin | -0.00753079 |
| KRT15 | keratin 15, type I | -0.00747272 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | -0.00744926 |
| GPX3 | glutathione peroxidase 3 | -0.00739929 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | -0.00737763 |
| HIST1H2BD | histone cluster 1, H2bd | -0.00737048 |
| TMEM14B | transmembrane protein 14B | -0.00723783 |
| HBD | hemoglobin, delta | -0.00721058 |
| TMEM126B | transmembrane protein 126B | -0.00720912 |
| IFT20 | intraflagellar transport 20 | -0.00720232 |
| LRRC17 | leucine rich repeat containing 17 | -0.00714184 |
| S100A12 | S100 calcium binding protein A12 | -0.00709291 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | -0.00709176 |
| CTSS | cathepsin S | -0.00698625 |
| ZNHIT1 | zinc finger, HIT-type containing 1 | -0.00696319 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.00695425 |
| MGST3 | microsomal glutathione S-transferase 3 | -0.00693961 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00692927 |
| CPM | carboxypeptidase M | -0.00687399 |
| NME5 | NME/NM23 family member 5 | -0.00686965 |
| SOX10 | SRY (sex determining region Y)-box 10 | -0.00685855 |
| HTRA1 | HtrA serine peptidase 1 | -0.00685598 |
| LY96 | lymphocyte antigen 96 | -0.00685325 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.00684516 |
| ANXA2P2 | annexin A2 pseudogene 2 | -0.00683285 |
| TSPO | translocator protein (18kDa) | -0.00677872 |
| CHI3L2 | chitinase 3-like 2 | -0.00677534 |
| SLC38A6 | solute carrier family 38, member 6 | -0.00676815 |
| KRT23 | keratin 23, type I | -0.00675428 |
| C1ORF54 | chromosome 1 open reading frame 54 | -0.00674837 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.00672441 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.00670853 |
| SRGN | serglycin | -0.00666258 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | -0.00665628 |
| CYBA | cytochrome b-245, alpha polypeptide | -0.00665614 |
| ACOT13 | acyl-CoA thioesterase 13 | -0.00663156 |
| CEL | carboxyl ester lipase | -0.00661806 |
| BLVRB | biliverdin reductase B | -0.00654629 |
| RGS4 | regulator of G-protein signaling 4 | -0.00654112 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.00651987 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.00651509 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit | -0.00650996 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.0064776 |
| MAL | mal, T-cell differentiation protein | -0.00646232 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00646099 |
| LOX | lysyl oxidase | -0.00645632 |
| METRN | meteorin, glial cell differentiation regulator | -0.00642085 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.00636993 |
| RPL39L | ribosomal protein L39-like | -0.00633768 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | -0.00632051 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.00631467 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | -0.00631015 |
| BCL2A1 | BCL2-related protein A1 | -0.00631002 |
| ADM | adrenomedullin | -0.00630474 |
| CCNG2 | cyclin G2 | -0.00629989 |
| CRYM | crystallin, mu | -0.00626117 |
| TMEM47 | transmembrane protein 47 | -0.00625673 |
| GYPC | glycophorin C (Gerbich blood group) | -0.00621163 |
| FZD6 | frizzled class receptor 6 | -0.00619718 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00618717 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00618463 |
| ZIC1 | Zic family member 1 | -0.00616878 |
| MT1HL1 | metallothionein 1H-like 1 | -0.00615379 |
| TFRC | transferrin receptor | -0.00614331 |
| CIDEC | cell death-inducing DFFA-like effector c | -0.00614314 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.00614015 |
| LSM1 | LSM1, U6 small nuclear RNA associated | -0.00611194 |
| KRCC1 | lysine-rich coiled-coil 1 | -0.00609324 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -0.00608982 |
| TSPAN31 | tetraspanin 31 | -0.00603462 |
| CLDN10 | claudin 10 | -0.0060001 |
| SGCE | sarcoglycan, epsilon | -0.00599213 |
| PFN2 | profilin 2 | -0.00598747 |
| ADD3 | adducin 3 (gamma) | -0.00594158 |
| CETN2 | centrin, EF-hand protein, 2 | -0.00592835 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa | -0.00592698 |
| FAM107A | family with sequence similarity 107, member A | -0.00592679 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00590364 |
| VAMP5 | vesicle-associated membrane protein 5 | -0.00588788 |
| STOM | stomatin | -0.00586791 |
| EGR1 | early growth response 1 | -0.00586786 |
| ATP5MJ | ATP synthase membrane subunit j | -0.0058494 |
| BUD31 | BUD31 homolog (S. cerevisiae) | -0.00583225 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.00582942 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 | -0.00582732 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.00580679 |
| TAGLN3 | transgelin 3 | -0.00580441 |
| CD48 | CD48 molecule | -0.00580003 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | -0.00579967 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00579934 |
| SKP1 | S-phase kinase-associated protein 1 | -0.00578753 |
| GPM6B | glycoprotein M6B | -0.00578441 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | -0.00577953 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.00577214 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | -0.00576284 |
| CRIPT | cysteine-rich PDZ-binding protein | -0.00574333 |
| MLF1 | myeloid leukemia factor 1 | -0.00574242 |
| BST1 | bone marrow stromal cell antigen 1 | -0.00573001 |
| UPK1B | uroplakin 1B | -0.00572975 |
| BET1 | Bet1 golgi vesicular membrane trafficking protein | -0.00572924 |
| SELENOT | selenoprotein T | -0.00571918 |
| FOXD1 | forkhead box D1 | -0.00570946 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.00567822 |
| COMMD10 | COMM domain containing 10 | -0.00566915 |
| G0S2 | G0/G1 switch 2 | -0.00566639 |
| LAMTOR3 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 | -0.00565401 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -0.00565145 |
| RHOBTB1 | Rho-related BTB domain containing 1 | -0.00563281 |
| DOK5 | docking protein 5 | -0.00560193 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.00559623 |
| FGF1 | fibroblast growth factor 1 (acidic) | -0.00559618 |
| NMB | neuromedin B | -0.0055955 |
| MME | membrane metallo-endopeptidase | -0.00556141 |
| NDP | Norrie disease (pseudoglioma) | -0.00552885 |
| PLPP3 | phospholipid phosphatase 3 | -0.00551495 |
| MMP8 | matrix metallopeptidase 8 | -0.00551474 |
| NDUFB5 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa | -0.00550921 |
| TXNDC9 | thioredoxin domain containing 9 | -0.00550137 |
| FABP7 | fatty acid binding protein 7, brain | -0.00548401 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | -0.00547783 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -0.0054775 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 | -0.00547614 |
| S100A7 | S100 calcium binding protein A7 | -0.00547184 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.00546662 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | -0.0054615 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.00545307 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.00543241 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | -0.00542972 |
| MT1M | metallothionein 1M | -0.00542773 |
| CD58 | CD58 molecule | -0.00541891 |
| TPGS2 | tubulin polyglutamylase complex subunit 2 | -0.00540578 |
| TMOD1 | tropomodulin 1 | -0.00540483 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -0.00540325 |
| BAALC | brain and acute leukemia, cytoplasmic | -0.00540119 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.00539648 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | -0.00539579 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.00538494 |
| GLRX | glutaredoxin (thioltransferase) | -0.00536453 |
| CD9 | CD9 molecule | -0.00535717 |
| MIR22HG | MIR22 host gene | -0.0053416 |
| GABARAPL2 | GABA(A) receptor-associated protein-like 2 | -0.00533956 |
| NRIP3 | nuclear receptor interacting protein 3 | -0.0053357 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.00533487 |
| PROM1 | prominin 1 | -0.005334 |
| PDCD10 | programmed cell death 10 | -0.00533036 |
| RAB29 | RAB29, member RAS oncogene family | -0.00532449 |
| BPGM | 2,3-bisphosphoglycerate mutase | -0.00532442 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | -0.0053229 |
| SCPEP1 | serine carboxypeptidase 1 | -0.00532139 |
| IDS | iduronate 2-sulfatase | -0.00532129 |
| IER3IP1 | immediate early response 3 interacting protein 1 | -0.00531933 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.00531425 |
| ACP1 | acid phosphatase 1, soluble | -0.00531009 |
| WDR7 | WD repeat domain 7 | -0.00530508 |
| MPO | myeloperoxidase | -0.00530479 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | -0.00529417 |
| MYNN | myoneurin | -0.00529391 |
| YIPF5 | Yip1 domain family, member 5 | -0.00527799 |
| RPA3 | replication protein A3, 14kDa | -0.00527743 |
| MT1H | metallothionein 1H | -0.00527326 |
| OAT | ornithine aminotransferase | -0.00527031 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | -0.005268 |
| SORT1 | sortilin 1 | -0.00526291 |
| NFU1 | NFU1 iron-sulfur cluster scaffold | -0.0052579 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.00523448 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | -0.00522414 |
| PLBD1 | phospholipase B domain containing 1 | -0.00520881 |
| RCHY1 | ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase | -0.00520625 |
| ANKRD46 | ankyrin repeat domain 46 | -0.00519631 |
| KRT7 | keratin 7, type II | -0.00517805 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00514327 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00513729 |
| MPC2 | mitochondrial pyruvate carrier 2 | -0.00513264 |
| GOLT1B | golgi transport 1B | -0.00512757 |
| CYB5A | cytochrome b5 type A (microsomal) | -0.00511453 |
| MMP9 | matrix metallopeptidase 9 | -0.00510777 |
| ATP5MF | ATP synthase membrane subunit f | -0.00509629 |
| HPGDS | hematopoietic prostaglandin D synthase | -0.00509623 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | -0.00509564 |
| DAZAP2 | DAZ associated protein 2 | -0.00508971 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00507012 |
| MGP | matrix Gla protein | -0.00506324 |
| VNN1 | vanin 1 | -0.00503875 |
| EFHD1 | EF-hand domain family, member D1 | -0.00503366 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00502605 |
| FGF13 | fibroblast growth factor 13 | -0.00501454 |
| KIAA0100 | KIAA0100 | -0.00500594 |
| S100B | S100 calcium binding protein B | -0.00500454 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | -0.00500269 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | -0.00498505 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.00496036 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.00495195 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00494957 |
| PDE8B | phosphodiesterase 8B | -0.00494668 |
| CDO1 | cysteine dioxygenase type 1 | -0.00494617 |
| ZNHIT3 | zinc finger, HIT-type containing 3 | -0.00494265 |
| GFAP | glial fibrillary acidic protein | -0.004931 |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) | -0.00493032 |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | -0.00492554 |
| LAMTOR5 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 | -0.00492011 |
| COMMD8 | COMM domain containing 8 | -0.00491756 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00491363 |
