NTRK2_drugactivation_66_GSE20358 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Kinase Perturbations
Category transcriptomics
Type kinase perturbation
Description kinase perturbation identified as [kinase gene symbol]_[perturbation]_[perturbation ID]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE20358
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Genes

600 genes differentially expressed following the NTRK2_drugactivation_66_GSE20358 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

increased expression

Symbol Name Standardized Value
TSPAN3 tetraspanin 3 5.96615
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 3.42693
DCTN3 dynactin 3 (p22) 3.02174
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit 2.98346
TFDP1 transcription factor Dp-1 2.92435
CNOT2 CCR4-NOT transcription complex, subunit 2 2.8527
PHLDA1 pleckstrin homology-like domain, family A, member 1 2.81409
MMS22L MMS22-like, DNA repair protein 2.78316
LAPTM5 lysosomal protein transmembrane 5 2.77356
NTAN1 N-terminal asparagine amidase 2.7344
MATR3 matrin 3 2.6441
CCNG1 cyclin G1 2.42523
HSPA14 heat shock 70kDa protein 14 2.41856
WDR45B WD repeat domain 45B 2.39083
WRNIP1 Werner helicase interacting protein 1 2.37747
FPGS folylpolyglutamate synthase 2.28192
SLC25A29 solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 2.22721
FAM227A family with sequence similarity 227, member A 2.21622
ZNF322 zinc finger protein 322 2.14751
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic) 2.06823
COPB2 coatomer protein complex, subunit beta 2 (beta prime) 2.04374
DYNLL1 dynein, light chain, LC8-type 1 2.03961
FDFT1 farnesyl-diphosphate farnesyltransferase 1 2.02027
ACAA2 acetyl-CoA acyltransferase 2 1.96554
TMEM184B transmembrane protein 184B 1.9062
STK39 serine threonine kinase 39 1.88558
TRAPPC13 trafficking protein particle complex 13 1.88243
KLF15 Kruppel-like factor 15 1.83585
ITM2B integral membrane protein 2B 1.81193
GLCCI1 glucocorticoid induced 1 1.8035
NUP205 nucleoporin 205kDa 1.79062
NOX1 NADPH oxidase 1 1.68293
CABLES2 Cdk5 and Abl enzyme substrate 2 1.673
SIRT5 sirtuin 5 1.63297
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 1.60936
HHEX hematopoietically expressed homeobox 1.60752
TMEM37 transmembrane protein 37 1.57784
DPH7 diphthamide biosynthesis 7 1.55999
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 1.55905
MYO1C myosin IC 1.55543
MALSU1 mitochondrial assembly of ribosomal large subunit 1 1.51592
TPRA1 transmembrane protein, adipocyte asscociated 1 1.51223
EID1 EP300 interacting inhibitor of differentiation 1 1.50171
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26 1.50085
DENND2D DENN/MADD domain containing 2D 1.48633
ENO1 enolase 1, (alpha) 1.48519
MDH1 malate dehydrogenase 1, NAD (soluble) 1.47931
VDAC3 voltage-dependent anion channel 3 1.47019
PHF2 PHD finger protein 2 1.46126
TXNDC12 thioredoxin domain containing 12 (endoplasmic reticulum) 1.4449
FBN1 fibrillin 1 1.41669
PLAUR plasminogen activator, urokinase receptor 1.39087
TMEM87B transmembrane protein 87B 1.38384
FGL1 fibrinogen-like 1 1.35629
UGP2 UDP-glucose pyrophosphorylase 2 1.35475
KLC4 kinesin light chain 4 1.33156
DOCK1 dedicator of cytokinesis 1 1.32953
OARD1 O-acyl-ADP-ribose deacylase 1 1.31485
LAMP2 lysosomal-associated membrane protein 2 1.30428
ZNF131 zinc finger protein 131 1.29333
PRTG protogenin 1.29164
COL13A1 collagen, type XIII, alpha 1 1.28928
STOML2 stomatin (EPB72)-like 2 1.28715
CCNE2 cyclin E2 1.28608
BAIAP2L1 BAI1-associated protein 2-like 1 1.25794
NUCB2 nucleobindin 2 1.25576
IFI30 interferon, gamma-inducible protein 30 1.2502
FBXO33 F-box protein 33 1.22664
COX18 COX18 cytochrome c oxidase assembly factor 1.21703
PCYOX1 prenylcysteine oxidase 1 1.20825
SARM1 sterile alpha and TIR motif containing 1 1.20818
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 1.2005
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 1.19269
CNIH1 cornichon family AMPA receptor auxiliary protein 1 1.18843
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 1.1841
FAM104A family with sequence similarity 104, member A 1.17944
TMEM14C transmembrane protein 14C 1.17255
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial 1.16713
TECR trans-2,3-enoyl-CoA reductase 1.15515
ZBTB41 zinc finger and BTB domain containing 41 1.15194
IFNAR2 interferon (alpha, beta and omega) receptor 2 1.15063
RAD21 RAD21 homolog (S. pombe) 1.14178
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 1.13574
SYNDIG1 synapse differentiation inducing 1 1.1357
POGLUT1 protein O-glucosyltransferase 1 1.12753
TNC tenascin C 1.12358
FUNDC2 FUN14 domain containing 2 1.12016
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 1.11898
PKD2L2 polycystic kidney disease 2-like 2 1.11109
CTSS cathepsin S 1.09429
FAM89B family with sequence similarity 89, member B 1.09344
ADNP2 ADNP homeobox 2 1.09194
GALP galanin-like peptide 1.08878
TEX261 testis expressed 261 1.08832
PPT1 palmitoyl-protein thioesterase 1 1.08581
PSPH phosphoserine phosphatase 1.08244
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 1.08196
RNPEP arginyl aminopeptidase (aminopeptidase B) 1.07944
HEXB hexosaminidase B (beta polypeptide) 1.07488
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 1.07123
POLR3H polymerase (RNA) III (DNA directed) polypeptide H (22.9kD) 1.06954
EPS8 epidermal growth factor receptor pathway substrate 8 1.06688
LIN37 lin-37 DREAM MuvB core complex component 1.06613
TSN translin 1.06587
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 1.06578
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 1.06424
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 1.06388
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 1.06308
GCSH glycine cleavage system protein H (aminomethyl carrier) 1.05777
WDR13 WD repeat domain 13 1.04872
RNGTT RNA guanylyltransferase and 5'-phosphatase 1.04072
BLVRA biliverdin reductase A 1.04053
CHCHD4 coiled-coil-helix-coiled-coil-helix domain containing 4 1.03966
RAB3IL1 RAB3A interacting protein (rabin3)-like 1 1.03784
NUDT22 nudix (nucleoside diphosphate linked moiety X)-type motif 22 1.03698
IRGQ immunity-related GTPase family, Q 1.03457
CLEC10A C-type lectin domain family 10, member A 1.03406
ANAPC1 anaphase promoting complex subunit 1 1.03063
PARP8 poly (ADP-ribose) polymerase family, member 8 1.03028
SLC35E4 solute carrier family 35, member E4 1.02657
GBA2 glucosidase, beta (bile acid) 2 1.02374
RARS2 arginyl-tRNA synthetase 2, mitochondrial 1.02012
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 1.01867
COL3A1 collagen, type III, alpha 1 1.01773
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 1.00905
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.00762
GPSM2 G-protein signaling modulator 2 1.00609
USP31 ubiquitin specific peptidase 31 1.00505
SRR serine racemase 1.0046
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 1.00335
WDR77 WD repeat domain 77 0.997679
NSFL1C NSFL1 (p97) cofactor (p47) 0.995236
UBE2E3 ubiquitin-conjugating enzyme E2E 3 0.995155
ACSS2 acyl-CoA synthetase short-chain family member 2 0.994236
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) 0.993953
CYC1 cytochrome c-1 0.992559
ENO2 enolase 2 (gamma, neuronal) 0.991213
MANF mesencephalic astrocyte-derived neurotrophic factor 0.986143
COL14A1 collagen, type XIV, alpha 1 0.98589
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha 0.985289
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 0.985215
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like 0.977507
APTX aprataxin 0.975084
DMTN dematin actin binding protein 0.97089
CPOX coproporphyrinogen oxidase 0.963847
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) 0.963578
SLC38A2 solute carrier family 38, member 2 0.961131
ATRN attractin 0.957172
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) 0.957171
HEBP2 heme binding protein 2 0.944389
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 0.942686
NDUFAF3 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 0.933857
YBX3 Y box binding protein 3 0.933403
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase 0.932754
LMO2 LIM domain only 2 (rhombotin-like 1) 0.930885
TACC1 transforming, acidic coiled-coil containing protein 1 0.930857
MAOA monoamine oxidase A 0.929317
LAMA2 laminin, alpha 2 0.92768
LTA4H leukotriene A4 hydrolase 0.923473
RASSF6 Ras association (RalGDS/AF-6) domain family member 6 0.922399
CBX1 chromobox homolog 1 0.919436
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal) 0.918473
KLHL24 kelch-like family member 24 0.915071
MANBAL mannosidase, beta A, lysosomal-like 0.914201
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1) 0.913597
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.912589
NRBF2 nuclear receptor binding factor 2 0.911834
SNX9 sorting nexin 9 0.908527
LEMD2 LEM domain containing 2 0.906241
DPY19L1 dpy-19-like 1 (C. elegans) 0.905775
CNRIP1 cannabinoid receptor interacting protein 1 0.904349
ELMO2 engulfment and cell motility 2 0.897743
NFU1 NFU1 iron-sulfur cluster scaffold 0.896015
CERS2 ceramide synthase 2 0.893732
TBRG1 transforming growth factor beta regulator 1 0.892473
MBOAT1 membrane bound O-acyltransferase domain containing 1 0.892042
NSUN4 NOP2/Sun domain family, member 4 0.888195
FLCN folliculin 0.883345
TMOD3 tropomodulin 3 (ubiquitous) 0.880596
DKC1 dyskeratosis congenita 1, dyskerin 0.875101
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial 0.874979
MAPK3 mitogen-activated protein kinase 3 0.8749
STON2 stonin 2 0.874534
CR1L complement component (3b/4b) receptor 1-like 0.873676
PLSCR1 phospholipid scramblase 1 0.87297
TMX1 thioredoxin-related transmembrane protein 1 0.872385
MAOB monoamine oxidase B 0.867034
IFT43 intraflagellar transport 43 0.862712
FCHSD2 FCH and double SH3 domains 2 0.862045
TLCD1 TLC domain containing 1 0.861119
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 0.858054
FBXO4 F-box protein 4 0.857601
PRDX3 peroxiredoxin 3 0.856849
MRPS31 mitochondrial ribosomal protein S31 0.853308
GRIPAP1 GRIP1 associated protein 1 0.850367
TUBGCP4 tubulin, gamma complex associated protein 4 0.84927
SMIM8 small integral membrane protein 8 0.844759
ACVR2A activin A receptor, type IIA 0.842824
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.836208
DGKA diacylglycerol kinase, alpha 80kDa 0.83161
TMEM203 transmembrane protein 203 0.830397
CCDC125 coiled-coil domain containing 125 0.830128
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 0.829755
FBXL5 F-box and leucine-rich repeat protein 5 0.829643
COL5A2 collagen, type V, alpha 2 0.829598
PGAM1 phosphoglycerate mutase 1 (brain) 0.827702
COL4A1 collagen, type IV, alpha 1 0.823882
CDIP1 cell death-inducing p53 target 1 0.82271
RBBP7 retinoblastoma binding protein 7 0.822433
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) 0.822313
NCAPH2 non-SMC condensin II complex, subunit H2 0.821244
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit 0.81698
PRRX2 paired related homeobox 2 0.813378
SFXN5 sideroflexin 5 0.813163
RAB32 RAB32, member RAS oncogene family 0.811705
CST3 cystatin C 0.809621
NID2 nidogen 2 (osteonidogen) 0.807357
CWC27 CWC27 spliceosome-associated protein homolog (S. cerevisiae) 0.806795
RBM11 RNA binding motif protein 11 0.800142
PELI1 pellino E3 ubiquitin protein ligase 1 0.799824
MYADM myeloid-associated differentiation marker 0.79079
LRRK1 leucine-rich repeat kinase 1 0.789592
MEX3D mex-3 RNA binding family member D 0.789363
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 0.785205
CDK11A cyclin-dependent kinase 11A 0.784085
OPTN optineurin 0.782646
ARL4A ADP-ribosylation factor-like 4A 0.781897
KCTD4 potassium channel tetramerization domain containing 4 0.778502
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2 0.776217
MTIF2 mitochondrial translational initiation factor 2 0.774232
ARFIP2 ADP-ribosylation factor interacting protein 2 0.773035
JOSD2 Josephin domain containing 2 0.772818
RNF115 ring finger protein 115 0.772654
SNX16 sorting nexin 16 0.772549
CHKB choline kinase beta 0.772149
PGRMC1 progesterone receptor membrane component 1 0.771181
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 0.770415
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 0.769709
SEC62 SEC62 homolog (S. cerevisiae) 0.768411
DCUN1D5 DCN1, defective in cullin neddylation 1, domain containing 5 0.767564
GLIPR1 GLI pathogenesis-related 1 0.767239
ANKFY1 ankyrin repeat and FYVE domain containing 1 0.766947
KLC2 kinesin light chain 2 0.766856
USO1 USO1 vesicle transport factor 0.766441
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 0.765412
YBEY ybeY metallopeptidase (putative) 0.764177
VCPKMT valosin containing protein lysine (K) methyltransferase 0.76235
ERMARD ER membrane-associated RNA degradation 0.761095
WBP11 WW domain binding protein 11 0.760272
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3 0.760092
ARMC1 armadillo repeat containing 1 0.759898
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae) 0.759075
TRNAU1AP tRNA selenocysteine 1 associated protein 1 0.757653
SEPHS1 selenophosphate synthetase 1 0.755547
RNASEK ribonuclease, RNase K 0.7548
LRRC17 leucine rich repeat containing 17 0.754327
NGLY1 N-glycanase 1 0.754223
PRSS23 protease, serine, 23 0.753858
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 0.752856
RHPN2 rhophilin, Rho GTPase binding protein 2 0.751193
KIAA1217 KIAA1217 0.750131
OLFML2A olfactomedin-like 2A 0.749289
KIF18B kinesin family member 18B 0.746487
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 0.745218
CLCN3 chloride channel, voltage-sensitive 3 0.744964
ZNF189 zinc finger protein 189 0.744637
PGM1 phosphoglucomutase 1 0.744413
FMR1 fragile X mental retardation 1 0.743952
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 0.742615
GSTO1 glutathione S-transferase omega 1 0.740542
SLC35E3 solute carrier family 35, member E3 0.739641
PCSK6 proprotein convertase subtilisin/kexin type 6 0.737023
MTCH2 mitochondrial carrier 2 0.736589
UBR1 ubiquitin protein ligase E3 component n-recognin 1 0.73624
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.73599
COPG1 coatomer protein complex, subunit gamma 1 0.734851
CCNF cyclin F 0.73261
JADE1 jade family PHD finger 1 0.73245
SAT2 spermidine/spermine N1-acetyltransferase family member 2 0.731039
EIF4E3 eukaryotic translation initiation factor 4E family member 3 0.730662
NECAP1 NECAP endocytosis associated 1 0.72874
RAP2A RAP2A, member of RAS oncogene family 0.722399
WBP5 WW domain binding protein 5 0.722053
ZNF652 zinc finger protein 652 0.718778
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 0.717277
ICE1 interactor of little elongation complex ELL subunit 1 0.716229
RIOK2 RIO kinase 2 0.715362
RABL6 RAB, member RAS oncogene family-like 6 0.713527
TFG TRK-fused gene 0.713352
NDUFB10 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa 0.713165
TPBG trophoblast glycoprotein 0.712254
PHIP pleckstrin homology domain interacting protein 0.712113
RFX4 regulatory factor X, 4 (influences HLA class II expression) 0.709441
HIRIP3 HIRA interacting protein 3 0.707895
TIMP2 TIMP metallopeptidase inhibitor 2 0.706842
SPNS1 spinster homolog 1 (Drosophila) 0.705622
ST7 suppression of tumorigenicity 7 0.704476
SCFD2 sec1 family domain containing 2 0.704254
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase 0.702491
RGS8 regulator of G-protein signaling 8 0.701679

decreased expression

Symbol Name Standardized Value
OXSR1 oxidative stress responsive 1 -3.55322
SERTAD4 SERTA domain containing 4 -3.53871
EXOC3L2 exocyst complex component 3-like 2 -2.91677
RLIM ring finger protein, LIM domain interacting -2.83734
TMEM51 transmembrane protein 51 -2.74086
RASL12 RAS-like, family 12 -2.62273
RFWD3 ring finger and WD repeat domain 3 -2.61726
TBC1D22A TBC1 domain family, member 22A -2.40044
PPP5C protein phosphatase 5, catalytic subunit -2.28241
FCGBP Fc fragment of IgG binding protein -2.23925
ERLIN2 ER lipid raft associated 2 -2.23144
INSR insulin receptor -2.22814
TUSC3 tumor suppressor candidate 3 -2.17321
PPP2R1B protein phosphatase 2, regulatory subunit A, beta -2.14738
ZW10 zw10 kinetochore protein -2.13049
PARP1 poly (ADP-ribose) polymerase 1 -2.07821
C2CD2 C2 calcium-dependent domain containing 2 -2.0679
FASTKD5 FAST kinase domains 5 -2.05918
EXOC2 exocyst complex component 2 -2.05844
TM2D1 TM2 domain containing 1 -2.05587
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa -2.03452
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase -2.03078
WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 -2.0075
GLG1 golgi glycoprotein 1 -1.98245
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) -1.94274
TSPAN15 tetraspanin 15 -1.86955
IFT140 intraflagellar transport 140 -1.85441
TMA16 translation machinery associated 16 homolog (S. cerevisiae) -1.81484
JAG1 jagged 1 -1.81237
PFDN2 prefoldin subunit 2 -1.8057
TEX14 testis expressed 14 -1.80517
PCBP1 poly(rC) binding protein 1 -1.78145
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 -1.77537
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast) -1.75557
TTC22 tetratricopeptide repeat domain 22 -1.7355
FRMD6 FERM domain containing 6 -1.72145
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) -1.6631
SRPK2 SRSF protein kinase 2 -1.60519
MSRB2 methionine sulfoxide reductase B2 -1.57625
SEPW1 selenoprotein W, 1 -1.5752
ZNF830 zinc finger protein 830 -1.57092
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -1.56336
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa -1.5459
THADA thyroid adenoma associated -1.53424
NKAIN3 Na+/K+ transporting ATPase interacting 3 -1.50926
TEFM transcription elongation factor, mitochondrial -1.48617
ARID1B AT rich interactive domain 1B (SWI1-like) -1.4846
NXPE3 neurexophilin and PC-esterase domain family, member 3 -1.48421
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4 -1.47431
PEX26 peroxisomal biogenesis factor 26 -1.46165
AP5B1 adaptor-related protein complex 5, beta 1 subunit -1.45216
ICOS inducible T-cell co-stimulator -1.38773
RPA1 replication protein A1, 70kDa -1.38249
RNF26 ring finger protein 26 -1.38229
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 -1.37449
ECH1 enoyl CoA hydratase 1, peroxisomal -1.37024
PPME1 protein phosphatase methylesterase 1 -1.36952
MMGT1 membrane magnesium transporter 1 -1.36498
OLFM1 olfactomedin 1 -1.35908
WIPI1 WD repeat domain, phosphoinositide interacting 1 -1.33828
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) -1.32878
NELFA negative elongation factor complex member A -1.31507
GABPB1 GA binding protein transcription factor, beta subunit 1 -1.31491
TSEN2 TSEN2 tRNA splicing endonuclease subunit -1.30102
ZC3H11A zinc finger CCCH-type containing 11A -1.2981
ZFC3H1 zinc finger, C3H1-type containing -1.29564
ZDHHC3 zinc finger, DHHC-type containing 3 -1.28746
CDX2 caudal type homeobox 2 -1.28692
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase -1.28017
PTGR1 prostaglandin reductase 1 -1.27165
GAA glucosidase, alpha; acid -1.26891
ATP11B ATPase, class VI, type 11B -1.26873
HHIPL1 HHIP-like 1 -1.26637
SPRY4 sprouty homolog 4 (Drosophila) -1.26495
BSDC1 BSD domain containing 1 -1.2626
SCMH1 sex comb on midleg homolog 1 (Drosophila) -1.26142
GMIP GEM interacting protein -1.24882
CCDC96 coiled-coil domain containing 96 -1.24107
CTNNBL1 catenin, beta like 1 -1.23824
MAGIX MAGI family member, X-linked -1.23546
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 -1.2334
GNPTG N-acetylglucosamine-1-phosphate transferase, gamma subunit -1.23063
POLM polymerase (DNA directed), mu -1.22273
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 -1.21981
ACSF3 acyl-CoA synthetase family member 3 -1.20882
MSX1 msh homeobox 1 -1.20433
PDCD7 programmed cell death 7 -1.20253
FOPNL FGFR1OP N-terminal like -1.19837
MRRF mitochondrial ribosome recycling factor -1.19209
SNX6 sorting nexin 6 -1.18871
CAPN1 calpain 1, (mu/I) large subunit -1.18391
KARS lysyl-tRNA synthetase -1.18156
IGBP1 immunoglobulin (CD79A) binding protein 1 -1.17078
FAM71E1 family with sequence similarity 71, member E1 -1.16642
WARS tryptophanyl-tRNA synthetase -1.16459
CARKD carbohydrate kinase domain containing -1.16432
RNF217 ring finger protein 217 -1.15568
PDE7A phosphodiesterase 7A -1.15483
ASF1B anti-silencing function 1B histone chaperone -1.15444
NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa -1.15097
ACTR10 actin-related protein 10 homolog (S. cerevisiae) -1.15066
CNN1 calponin 1, basic, smooth muscle -1.14722
KAT7 K(lysine) acetyltransferase 7 -1.14631
PTBP1 polypyrimidine tract binding protein 1 -1.142
TKT transketolase -1.13296
DDHD1 DDHD domain containing 1 -1.12849
NAGK N-acetylglucosamine kinase -1.11838
NKAP NFKB activating protein -1.11237
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1 -1.10341
STIM1 stromal interaction molecule 1 -1.1018
TMOD4 tropomodulin 4 (muscle) -1.10178
RPP30 ribonuclease P/MRP 30kDa subunit -1.09911
LYPD3 LY6/PLAUR domain containing 3 -1.09723
GABARAPL1 GABA(A) receptor-associated protein like 1 -1.09713
QSOX1 quiescin Q6 sulfhydryl oxidase 1 -1.09478
LHFPL2 lipoma HMGIC fusion partner-like 2 -1.09408
DTD1 D-tyrosyl-tRNA deacylase 1 -1.09092
MINK1 misshapen-like kinase 1 -1.09038
CTNND1 catenin (cadherin-associated protein), delta 1 -1.08878
TSPAN9 tetraspanin 9 -1.08847
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic) -1.08679
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 -1.08509
FAM13B family with sequence similarity 13, member B -1.08437
STRADA STE20-related kinase adaptor alpha -1.08268
SRC SRC proto-oncogene, non-receptor tyrosine kinase -1.0808
TEAD2 TEA domain family member 2 -1.07918
PARG poly (ADP-ribose) glycohydrolase -1.07878
C1QTNF5 C1q and tumor necrosis factor related protein 5 -1.07442
SUMF2 sulfatase modifying factor 2 -1.07263
CNOT1 CCR4-NOT transcription complex, subunit 1 -1.06913
SAYSD1 SAYSVFN motif domain containing 1 -1.06539
ZNF180 zinc finger protein 180 -1.06113
KIFAP3 kinesin-associated protein 3 -1.05667
AAR2 AAR2 splicing factor homolog (S. cerevisiae) -1.05272
DLG4 discs, large homolog 4 (Drosophila) -1.05134
PROKR1 prokineticin receptor 1 -1.04956
TPGS2 tubulin polyglutamylase complex subunit 2 -1.04876
IL18BP interleukin 18 binding protein -1.0434
UBAC1 UBA domain containing 1 -1.04332
GRWD1 glutamate-rich WD repeat containing 1 -1.03972
KLHL8 kelch-like family member 8 -1.0376
LYRM9 LYR motif containing 9 -1.0275
PEF1 penta-EF-hand domain containing 1 -1.02042
TAS2R41 taste receptor, type 2, member 41 -1.01257
COPS7B COP9 signalosome subunit 7B -1.00831
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) -1.00794
NUB1 negative regulator of ubiquitin-like proteins 1 -1.00566
MCM3AP minichromosome maintenance complex component 3 associated protein -1.00379
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase -1.00166
MEP1A meprin A, alpha (PABA peptide hydrolase) -1.001
ZNF354A zinc finger protein 354A -1.00067
COMMD8 COMM domain containing 8 -1.0003
GOLGA2 golgin A2 -0.990768
SPATS2 spermatogenesis associated, serine-rich 2 -0.986688
TJAP1 tight junction associated protein 1 (peripheral) -0.977562
CKM creatine kinase, muscle -0.977424
ZBTB22 zinc finger and BTB domain containing 22 -0.975828
RPUSD4 RNA pseudouridylate synthase domain containing 4 -0.973398
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) -0.973372
ADRA1B adrenoceptor alpha 1B -0.973316
SOCS6 suppressor of cytokine signaling 6 -0.971351
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 -0.970095
RNF167 ring finger protein 167 -0.964673
SCLY selenocysteine lyase -0.96235
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -0.960488
PRCC papillary renal cell carcinoma (translocation-associated) -0.95964
BCL2L13 BCL2-like 13 (apoptosis facilitator) -0.959319
TMCC2 transmembrane and coiled-coil domain family 2 -0.959039
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 -0.956795
NF1 neurofibromin 1 -0.953064
C2CD2L C2CD2-like -0.950923
GAB1 GRB2-associated binding protein 1 -0.949482
SNRNP48 small nuclear ribonucleoprotein 48kDa (U11/U12) -0.946776
SYS1 Sys1 golgi trafficking protein -0.94576
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.944475
GOLM1 golgi membrane protein 1 -0.94424
TEN1 TEN1 CST complex subunit -0.939909
HELB helicase (DNA) B -0.939575
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.939292
WDR73 WD repeat domain 73 -0.938714
TMEM41B transmembrane protein 41B -0.936045
KBTBD4 kelch repeat and BTB (POZ) domain containing 4 -0.935107
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 -0.934965
GRHPR glyoxylate reductase/hydroxypyruvate reductase -0.933869
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa -0.924084
RFC3 replication factor C (activator 1) 3, 38kDa -0.923068
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 -0.921237
EI24 etoposide induced 2.4 -0.918613
MFSD11 major facilitator superfamily domain containing 11 -0.918547
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) -0.906045
HDDC2 HD domain containing 2 -0.90535
CAMKV CaM kinase-like vesicle-associated -0.901161
CD79B CD79b molecule, immunoglobulin-associated beta -0.900124
ATG4D autophagy related 4D, cysteine peptidase -0.899858
NIPAL2 NIPA-like domain containing 2 -0.898909
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2 -0.898523
FES FES proto-oncogene, tyrosine kinase -0.897357
WDPCP WD repeat containing planar cell polarity effector -0.896891
GIPC3 GIPC PDZ domain containing family, member 3 -0.896638
PPAPDC2 phosphatidic acid phosphatase type 2 domain containing 2 -0.890442
NARFL nuclear prelamin A recognition factor-like -0.890329
POLD2 polymerase (DNA directed), delta 2, accessory subunit -0.886633
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase -0.881032
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -0.880558
ELMO1 engulfment and cell motility 1 -0.879544
TCTEX1D2 Tctex1 domain containing 2 -0.877648
CLCC1 chloride channel CLIC-like 1 -0.876394
ALPI alkaline phosphatase, intestinal -0.873989
TRMT6 tRNA methyltransferase 6 -0.87338
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 -0.869851
KATNB1 katanin p80 (WD repeat containing) subunit B 1 -0.869718
CADPS2 Ca++-dependent secretion activator 2 -0.867492
GFER growth factor, augmenter of liver regeneration -0.866469
MRPL55 mitochondrial ribosomal protein L55 -0.865538
PIGO phosphatidylinositol glycan anchor biosynthesis, class O -0.865109
STX8 syntaxin 8 -0.864689
SDAD1 SDA1 domain containing 1 -0.864067
PHF7 PHD finger protein 7 -0.861037
UBE2J1 ubiquitin-conjugating enzyme E2, J1 -0.854878
MRPL2 mitochondrial ribosomal protein L2 -0.851613
NEMF nuclear export mediator factor -0.851405
HDAC7 histone deacetylase 7 -0.851264
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B -0.851097
ATCAY ataxia, cerebellar, Cayman type -0.850634
TLR7 toll-like receptor 7 -0.843579
KDM3B lysine (K)-specific demethylase 3B -0.843249
ZBTB24 zinc finger and BTB domain containing 24 -0.840361
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 -0.838643
ACIN1 apoptotic chromatin condensation inducer 1 -0.83554
CANT1 calcium activated nucleotidase 1 -0.835516
RBM22 RNA binding motif protein 22 -0.834998
ZHX2 zinc fingers and homeoboxes 2 -0.834926
IHH indian hedgehog -0.833847
PURG purine-rich element binding protein G -0.833034
EXOC3 exocyst complex component 3 -0.830686
SDSL serine dehydratase-like -0.827926
TMEM106C transmembrane protein 106C -0.82456
ACP2 acid phosphatase 2, lysosomal -0.823865
BDH2 3-hydroxybutyrate dehydrogenase, type 2 -0.822756
GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae) -0.8225
OXNAD1 oxidoreductase NAD-binding domain containing 1 -0.822062
CNKSR3 CNKSR family member 3 -0.820247
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 -0.819312
GNAS GNAS complex locus -0.816671
AHDC1 AT hook, DNA binding motif, containing 1 -0.815806
TMEM74B transmembrane protein 74B -0.815142
FAM134A family with sequence similarity 134, member A -0.814806
ICE2 interactor of little elongation complex ELL subunit 2 -0.812253
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa -0.811037
TPST2 tyrosylprotein sulfotransferase 2 -0.808267
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 -0.804877
PTCD3 pentatricopeptide repeat domain 3 -0.804262
RNMTL1 RNA methyltransferase like 1 -0.803993
USPL1 ubiquitin specific peptidase like 1 -0.803375
RNF43 ring finger protein 43 -0.80337
ESR1 estrogen receptor 1 -0.803232
YPEL2 yippee-like 2 (Drosophila) -0.802387
SCCPDH saccharopine dehydrogenase (putative) -0.799753
ALK anaplastic lymphoma receptor tyrosine kinase -0.799711
NFE2L1 nuclear factor, erythroid 2-like 1 -0.798649
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) -0.798548
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 -0.798265
PEMT phosphatidylethanolamine N-methyltransferase -0.79523
GJA1 gap junction protein, alpha 1, 43kDa -0.794889
FABP3 fatty acid binding protein 3, muscle and heart -0.793817
TMEM101 transmembrane protein 101 -0.792522
PHB prohibitin -0.792335
GLE1 GLE1 RNA export mediator -0.79022
WNK4 WNK lysine deficient protein kinase 4 -0.788803
FAM20C family with sequence similarity 20, member C -0.786799
DUT deoxyuridine triphosphatase -0.785913
WDR81 WD repeat domain 81 -0.785094
TMEM178B transmembrane protein 178B -0.782515
MSRB1 methionine sulfoxide reductase B1 -0.782421
ACO2 aconitase 2, mitochondrial -0.778976
HNRNPM heterogeneous nuclear ribonucleoprotein M -0.77871
RAD52 RAD52 homolog (S. cerevisiae) -0.777669
MED10 mediator complex subunit 10 -0.775808
AKAP8 A kinase (PRKA) anchor protein 8 -0.775701
EXOC6B exocyst complex component 6B -0.773032
DEK DEK proto-oncogene -0.769242
CCAR2 cell cycle and apoptosis regulator 2 -0.768242
ANKRD46 ankyrin repeat domain 46 -0.765696
ZNF142 zinc finger protein 142 -0.76558
PTPRA protein tyrosine phosphatase, receptor type, A -0.763631
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.763569
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 -0.761019
NUP188 nucleoporin 188kDa -0.76026
ELP6 elongator acetyltransferase complex subunit 6 -0.760094
WASH1 WAS protein family homolog 1 -0.759883
MYO5B myosin VB -0.758376
IL2RG interleukin 2 receptor, gamma -0.757832
AAGAB alpha- and gamma-adaptin binding protein -0.757125
POGZ pogo transposable element with ZNF domain -0.755254
CDC37 cell division cycle 37 -0.752455
MYPOP Myb-related transcription factor, partner of profilin -0.751037
RANBP6 RAN binding protein 6 -0.749642
EED embryonic ectoderm development -0.749303
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) -0.748897
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 -0.748721