| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | neurotrophic tyrosine kinase, receptor, type 3|This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011] (NCBI Entrez Gene Database, 4916) |
| External Link | https://ncbi.nlm.nih.gov/gene/4916 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the NTRK3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0325686 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.0190943 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.0166974 |
| S100A10 | S100 calcium binding protein A10 | 0.0128829 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0122684 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.0116079 |
| A2M | alpha-2-macroglobulin | 0.011573 |
| NID1 | nidogen 1 | 0.0114214 |
| RAI14 | retinoic acid induced 14 | 0.0112101 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0107295 |
| GNAS | GNAS complex locus | 0.0103439 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0102998 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00960774 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0093846 |
| SYNM | synemin, intermediate filament protein | 0.00929663 |
| HOPX | HOP homeobox | 0.00924803 |
| MARCKSL1 | MARCKS-like 1 | 0.00923534 |
| VDAC1 | voltage-dependent anion channel 1 | 0.00888377 |
| RTN1 | reticulon 1 | 0.00858012 |
| FGG | fibrinogen gamma chain | 0.00856571 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00855811 |
| PMP22 | peripheral myelin protein 22 | 0.00824703 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00819957 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | 0.00809765 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.00808882 |
| OLFM4 | olfactomedin 4 | 0.00807861 |
| IFI44L | interferon-induced protein 44-like | 0.00798288 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.00796614 |
| CAST | calpastatin | 0.00785745 |
| DMD | dystrophin | 0.00784993 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | 0.00783827 |
| PRKCA | protein kinase C, alpha | 0.00768822 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.00768722 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00765028 |
| APOB | apolipoprotein B | 0.0076402 |
| VWF | von Willebrand factor | 0.00755007 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.00748509 |
| NRCAM | neuronal cell adhesion molecule | 0.00747828 |
| BAG3 | BCL2-associated athanogene 3 | 0.0074753 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | 0.00746567 |
| KIF20A | kinesin family member 20A | 0.00735023 |
| PLPP3 | phospholipid phosphatase 3 | 0.00719712 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.00715681 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 0.00709891 |
| CD320 | CD320 molecule | 0.00700945 |
| PLXND1 | plexin D1 | 0.0069816 |
| HNMT | histamine N-methyltransferase | 0.00697489 |
| ORM1 | orosomucoid 1 | 0.00691504 |
| SNX10 | sorting nexin 10 | 0.00690793 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00678596 |
| PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | 0.00671195 |
| FZD5 | frizzled class receptor 5 | 0.00669603 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.00666141 |
| APOC3 | apolipoprotein C-III | 0.00659229 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00650064 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | 0.00649373 |
| CD93 | CD93 molecule | 0.00644576 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.00641164 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00637953 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.00636193 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) | 0.00636136 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | 0.0063409 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.00632171 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00629317 |
| NELL1 | NEL-like 1 (chicken) | 0.00628671 |
| ITGA7 | integrin, alpha 7 | 0.00626269 |
| AGR2 | anterior gradient 2 | 0.00624329 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.00623136 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.00622952 |
| HOMER1 | homer scaffolding protein 1 | 0.00618935 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.00617066 |
| PLK2 | polo-like kinase 2 | 0.00615254 |
| TGM2 | transglutaminase 2 | 0.00615037 |
| NFIB | nuclear factor I/B | 0.00613127 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | 0.00613119 |
| DPYD | dihydropyrimidine dehydrogenase | 0.00611592 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 | 0.00605362 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.00603738 |
| NPY1R | neuropeptide Y receptor Y1 | 0.00601489 |
| COL21A1 | collagen, type XXI, alpha 1 | 0.00601107 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | 0.00600083 |
| MATN2 | matrilin 2 | 0.00599005 |
| CDO1 | cysteine dioxygenase type 1 | 0.00597794 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.00595257 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | 0.00595055 |
| TBX2 | T-box 2 | 0.00593496 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00593108 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | 0.00591618 |
| TYMP | thymidine phosphorylase | 0.00590423 |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | 0.00589355 |
| ELP1 | elongator acetyltransferase complex subunit 1 | 0.00589092 |
| REG1A | regenerating islet-derived 1 alpha | 0.00588922 |
| TFF1 | trefoil factor 1 | 0.00587882 |
| MMP12 | matrix metallopeptidase 12 | 0.00586593 |
| MAP1B | microtubule-associated protein 1B | 0.00585075 |
| COCH | cochlin | 0.00582668 |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 | 0.00582068 |
| PNMA1 | paraneoplastic Ma antigen 1 | 0.00581423 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | 0.00579757 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00579363 |
| QKI | QKI, KH domain containing, RNA binding | 0.00578816 |
| CHRDL1 | chordin-like 1 | 0.00577934 |
| TCTA | T-cell leukemia translocation altered | 0.00577019 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.00576562 |
| FZD7 | frizzled class receptor 7 | 0.00574382 |
| WASHC4 | WASH complex subunit 4 | 0.00572244 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | 0.00570453 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0057038 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0056954 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00569036 |
| FOXF1 | forkhead box F1 | 0.00568566 |
| MSX1 | msh homeobox 1 | 0.00566828 |
| FGA | fibrinogen alpha chain | 0.00566322 |
| CCNB1 | cyclin B1 | 0.00564412 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.00563962 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.00560663 |
| TTTY15 | testis-specific transcript, Y-linked 15 (non-protein coding) | 0.00560577 |
| FCGBP | Fc fragment of IgG binding protein | 0.00559424 |
| PDGFD | platelet derived growth factor D | 0.0055895 |
| PTCH1 | patched 1 | 0.00555519 |
| CD99 | CD99 molecule | 0.0055402 |
| INHBB | inhibin, beta B | 0.00553342 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | 0.00551948 |
| EDNRB | endothelin receptor type B | 0.00551533 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.00550963 |
| CNR1 | cannabinoid receptor 1 (brain) | 0.00547386 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.00546112 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00545105 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00544538 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 0.00544455 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | 0.00542927 |
| NES | nestin | 0.0054089 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00537837 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.0053632 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 0.00535267 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.00535029 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00533712 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00533598 |
| COL14A1 | collagen, type XIV, alpha 1 | 0.00533255 |
| PPAP2A | phosphatidic acid phosphatase type 2A | 0.00531656 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.00528593 |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.00528579 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00528338 |
| APOA2 | apolipoprotein A-II | 0.00526877 |
| REG3A | regenerating islet-derived 3 alpha | 0.00525695 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | 0.00525606 |
| TSC22D2 | TSC22 domain family, member 2 | 0.00525047 |
| MGLL | monoglyceride lipase | 0.00524792 |
| TRIB2 | tribbles pseudokinase 2 | 0.00522923 |
| AHR | aryl hydrocarbon receptor | 0.00521925 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.00520635 |
| ENOPH1 | enolase-phosphatase 1 | 0.00519826 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00516453 |
| ASPH | aspartate beta-hydroxylase | 0.00515833 |
| GPX3 | glutathione peroxidase 3 | 0.00514007 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.0051218 |
| C4BPA | complement component 4 binding protein, alpha | 0.00510301 |
| CAV2 | caveolin 2 | 0.00509695 |
| LRRC8B | leucine rich repeat containing 8 family, member B | 0.00509548 |
| DMXL1 | Dmx-like 1 | 0.00508569 |
| TUBB2B | tubulin, beta 2B class IIb | 0.0050829 |
| RBPMS | RNA binding protein with multiple splicing | 0.00507374 |
| KIF14 | kinesin family member 14 | 0.00506855 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.00503698 |
| ELOVL2 | ELOVL fatty acid elongase 2 | 0.0050331 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00503027 |
| MIA | melanoma inhibitory activity | 0.00501508 |
| CCL21 | chemokine (C-C motif) ligand 21 | 0.00501122 |
| LRP4 | low density lipoprotein receptor-related protein 4 | 0.0050054 |
| S100P | S100 calcium binding protein P | 0.00500046 |
| DCHS1 | dachsous cadherin-related 1 | 0.004999 |
| NELL2 | NEL-like 2 (chicken) | 0.00499477 |
| ALDOB | aldolase B, fructose-bisphosphate | 0.00496204 |
| EPAS1 | endothelial PAS domain protein 1 | 0.00492854 |
| FGF13 | fibroblast growth factor 13 | 0.00491832 |
| PRSS8 | protease, serine, 8 | 0.00489677 |
| MDFIC | MyoD family inhibitor domain containing | 0.00489399 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00488888 |
| FABP1 | fatty acid binding protein 1, liver | 0.00488638 |
| NPTX1 | neuronal pentraxin I | 0.00486881 |
| GPM6A | glycoprotein M6A | 0.00486842 |
| PLCB4 | phospholipase C, beta 4 | 0.00484775 |
| PDE8B | phosphodiesterase 8B | 0.00484101 |
| MGP | matrix Gla protein | 0.0048343 |
| OPN3 | opsin 3 | 0.00482404 |
| TAOK3 | TAO kinase 3 | 0.00479963 |
| GIMAP6 | GTPase, IMAP family member 6 | 0.00479188 |
| ANOS1 | anosmin 1 | 0.00478002 |
| CLIC3 | chloride intracellular channel 3 | 0.0047589 |
| RHOA | ras homolog family member A | 0.00474921 |
| LYVE1 | lymphatic vessel endothelial hyaluronan receptor 1 | 0.00474737 |
| AOC3 | amine oxidase, copper containing 3 | 0.00473547 |
| BZW2 | basic leucine zipper and W2 domains 2 | 0.00473429 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.00472057 |
| DPP4 | dipeptidyl-peptidase 4 | 0.00471785 |
| FDX1 | ferredoxin 1 | 0.00471524 |
| PLA1A | phospholipase A1 member A | 0.00470288 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00470241 |
| TM4SF4 | transmembrane 4 L six family member 4 | 0.00470149 |
| CFHR2 | complement factor H-related 2 | 0.00469632 |
| LEPR | leptin receptor | 0.00469458 |
| SMAD6 | SMAD family member 6 | 0.00469168 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 0.00468965 |
| COLEC12 | collectin sub-family member 12 | 0.00468928 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | 0.00467507 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.00467063 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.00466875 |
| PGAP3 | post-GPI attachment to proteins 3 | 0.00465972 |
| ARL4A | ADP-ribosylation factor-like 4A | 0.00465309 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | 0.00463673 |
| FOXN3 | forkhead box N3 | 0.00462204 |
| EFNA1 | ephrin-A1 | 0.00461719 |
| GALC | galactosylceramidase | 0.0046148 |
| SCRG1 | stimulator of chondrogenesis 1 | 0.00461315 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.00461112 |
| HEPH | hephaestin | 0.00459999 |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 | 0.00459934 |
| KRT17 | keratin 17, type I | 0.00459288 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | 0.00459075 |
| FHL1 | four and a half LIM domains 1 | 0.00458543 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.00457458 |
| COBL | cordon-bleu WH2 repeat protein | 0.00457308 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0045701 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.00456971 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.00456538 |
| CD200 | CD200 molecule | 0.00456447 |
| MAGEA3 | melanoma antigen family A3 | 0.00456036 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.00454071 |
| TIMP4 | TIMP metallopeptidase inhibitor 4 | 0.00453968 |
| CD209 | CD209 molecule | 0.00453427 |
| SIDT2 | SID1 transmembrane family, member 2 | 0.00451852 |
| ZW10 | zw10 kinetochore protein | 0.0045082 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.00450812 |
| CD163 | CD163 molecule | 0.0045065 |
| TUBA1A | tubulin, alpha 1a | 0.00450209 |
| WFDC1 | WAP four-disulfide core domain 1 | 0.00450145 |
| EHBP1 | EH domain binding protein 1 | 0.00450121 |
| PLVAP | plasmalemma vesicle associated protein | 0.0044992 |
| APOD | apolipoprotein D | 0.00448558 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.00447719 |
| CD14 | CD14 molecule | 0.00447576 |
| SFTPC | surfactant protein C | 0.00447488 |
| GPM6B | glycoprotein M6B | 0.00446564 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 | 0.00444962 |
| COL4A2 | collagen, type IV, alpha 2 | 0.00444934 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.00444277 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.00442989 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.00442624 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.0044215 |
| Symbol | Name | Standardized Value |
|---|---|---|
| XIC | X chromosome inactivation center | -0.0249527 |
| TXNDC9 | thioredoxin domain containing 9 | -0.0163596 |
| STK10 | serine/threonine kinase 10 | -0.0117639 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0109741 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.0107275 |
| COL11A1 | collagen, type XI, alpha 1 | -0.00998949 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | -0.00981363 |
| CSTA | cystatin A (stefin A) | -0.00963351 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.00933228 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.00931383 |
| ASS1 | argininosuccinate synthase 1 | -0.0091725 |
| PRPF4 | pre-mRNA processing factor 4 | -0.00896218 |
| CDC20 | cell division cycle 20 | -0.00891941 |
| SLC44A4 | solute carrier family 44, member 4 | -0.00886735 |
| CEL | carboxyl ester lipase | -0.00885746 |
| THBS2 | thrombospondin 2 | -0.00878925 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00876158 |
| ESR1 | estrogen receptor 1 | -0.00874292 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.00819535 |
| IFRD2 | interferon-related developmental regulator 2 | -0.00805929 |
| CDC42 | cell division cycle 42 | -0.00802707 |
| CTSK | cathepsin K | -0.00767171 |
| SLC25A46 | solute carrier family 25, member 46 | -0.00764205 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | -0.00761206 |
| TPM2 | tropomyosin 2 (beta) | -0.00757627 |
| BTG2 | BTG family, member 2 | -0.00752892 |
| INHBA | inhibin, beta A | -0.00741531 |
| LCN2 | lipocalin 2 | -0.0074109 |
| COL16A1 | collagen, type XVI, alpha 1 | -0.00736587 |
| AEBP1 | AE binding protein 1 | -0.0073204 |
| MMP9 | matrix metallopeptidase 9 | -0.00729444 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.00720651 |
| TPM4 | tropomyosin 4 | -0.00717013 |
| HOXC6 | homeobox C6 | -0.00704534 |
| AK1 | adenylate kinase 1 | -0.00696195 |
| SCG5 | secretogranin V | -0.00690178 |
| SPON1 | spondin 1, extracellular matrix protein | -0.00685254 |
| TMEM45A | transmembrane protein 45A | -0.00683733 |
| SULF1 | sulfatase 1 | -0.0068089 |
| MYL6B | myosin, light chain 6B, alkali, smooth muscle and non-muscle | -0.00677524 |
| LUM | lumican | -0.00675904 |
| NOX4 | NADPH oxidase 4 | -0.00671244 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -0.00670595 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | -0.00665368 |
| COPS7A | COP9 signalosome subunit 7A | -0.00662049 |
| KRT7 | keratin 7, type II | -0.00660569 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00658526 |
| ITM2C | integral membrane protein 2C | -0.00651487 |
| EMX2 | empty spiracles homeobox 2 | -0.00651233 |
| MT1E | metallothionein 1E | -0.00643938 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.00643121 |
| CA12 | carbonic anhydrase XII | -0.00642775 |
| BEX4 | brain expressed, X-linked 4 | -0.0064175 |
| SMC1A | structural maintenance of chromosomes 1A | -0.00639705 |
| MMP3 | matrix metallopeptidase 3 | -0.00633214 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00632475 |
| GAS6 | growth arrest-specific 6 | -0.00625891 |
| ZNF652 | zinc finger protein 652 | -0.00624233 |
| CA2 | carbonic anhydrase II | -0.00619905 |
| CFB | complement factor B | -0.00619564 |
| COMP | cartilage oligomeric matrix protein | -0.00617521 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00615233 |
| IL1A | interleukin 1, alpha | -0.00613766 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.00612289 |
| NVL | nuclear VCP-like | -0.00605849 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.0060452 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | -0.00603788 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00603047 |
| IL32 | interleukin 32 | -0.00601856 |
| MICU2 | mitochondrial calcium uptake 2 | -0.00595715 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.00593006 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -0.00591188 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | -0.00587794 |
| GSTP1 | glutathione S-transferase pi 1 | -0.00585906 |
| WT1 | Wilms tumor 1 | -0.00585374 |
| DUSP5 | dual specificity phosphatase 5 | -0.00582131 |
| SORBS3 | sorbin and SH3 domain containing 3 | -0.00577599 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.00577287 |
| CTSS | cathepsin S | -0.00576916 |
| SLC38A2 | solute carrier family 38, member 2 | -0.00576606 |
| ACP5 | acid phosphatase 5, tartrate resistant | -0.00576182 |
| TCL1A | T-cell leukemia/lymphoma 1A | -0.00575576 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.00572411 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.00571768 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.00571171 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | -0.00567495 |
| PFKM | phosphofructokinase, muscle | -0.00566227 |
| C3ORF14 | chromosome 3 open reading frame 14 | -0.0056586 |
| LRRC15 | leucine rich repeat containing 15 | -0.00565053 |
| UNC50 | unc-50 homolog (C. elegans) | -0.0056355 |
| MT1F | metallothionein 1F | -0.00560785 |
| AMH | anti-Mullerian hormone | -0.00558759 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.00557688 |
| FAM107A | family with sequence similarity 107, member A | -0.00553987 |
| CDK14 | cyclin-dependent kinase 14 | -0.00553934 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 | -0.00553673 |
| DSE | dermatan sulfate epimerase | -0.00549956 |
| TSPAN1 | tetraspanin 1 | -0.00546996 |
| LSP1 | lymphocyte-specific protein 1 | -0.00546386 |
| LIPT1 | lipoyltransferase 1 | -0.00544676 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00539411 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | -0.0053888 |
| LPXN | leupaxin | -0.00538769 |
| LTF | lactotransferrin | -0.00537059 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.00533271 |
| MFAP2 | microfibrillar-associated protein 2 | -0.00532631 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.00532399 |
| AMPD3 | adenosine monophosphate deaminase 3 | -0.00531627 |
| TAGLN | transgelin | -0.00530458 |
| ZNF430 | zinc finger protein 430 | -0.00527553 |
| ZNF160 | zinc finger protein 160 | -0.00527026 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.00526353 |
| RNF6 | ring finger protein (C3H2C3 type) 6 | -0.00525491 |
| IPO13 | importin 13 | -0.00523233 |
| KDM5C | lysine (K)-specific demethylase 5C | -0.00520926 |
| LYPLA1 | lysophospholipase I | -0.00519061 |
| EIF4A3 | eukaryotic translation initiation factor 4A3 | -0.00516892 |
| HOXC10 | homeobox C10 | -0.00513878 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.00513113 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | -0.00512833 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.00508939 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.00508519 |
| PREPL | prolyl endopeptidase-like | -0.0050597 |
| INTS6 | integrator complex subunit 6 | -0.00505252 |
| PLAUR | plasminogen activator, urokinase receptor | -0.00504305 |
| EHF | ets homologous factor | -0.00503898 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00503778 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.00503555 |
| ZBED2 | zinc finger, BED-type containing 2 | -0.00503305 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.00502608 |
| GRAMD2B | GRAM domain containing 2B | -0.00502137 |
| MXRA5 | matrix-remodelling associated 5 | -0.00501357 |
| ZNF117 | zinc finger protein 117 | -0.00499533 |
| GCH1 | GTP cyclohydrolase 1 | -0.00497967 |
| CCP110 | centriolar coiled coil protein 110kDa | -0.00497596 |
| ELANE | elastase, neutrophil expressed | -0.00497539 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00495084 |
| ZNF721 | zinc finger protein 721 | -0.00494437 |
| WBP5 | WW domain binding protein 5 | -0.0049344 |
| PDGFRL | platelet-derived growth factor receptor-like | -0.00493411 |
| PILRB | paired immunoglobin-like type 2 receptor beta | -0.00493331 |
| SLC43A3 | solute carrier family 43, member 3 | -0.00493103 |
| RETREG1 | reticulophagy regulator 1 | -0.0049219 |
| MTG1 | mitochondrial ribosome-associated GTPase 1 | -0.00492146 |
| PIP | prolactin-induced protein | -0.00492027 |
| GAS1 | growth arrest-specific 1 | -0.0049178 |
| DYRK4 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 | -0.00490845 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00490713 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.00490236 |
| ZNF44 | zinc finger protein 44 | -0.00487853 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | -0.0048772 |
| THBS1 | thrombospondin 1 | -0.00487531 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | -0.00487371 |
| EPYC | epiphycan | -0.00487121 |
| SGCE | sarcoglycan, epsilon | -0.00487061 |
| GPX1 | glutathione peroxidase 1 | -0.004859 |
| FOLR1 | folate receptor 1 (adult) | -0.00485258 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | -0.00481834 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | -0.00479915 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | -0.0047898 |
| PTK7 | protein tyrosine kinase 7 (inactive) | -0.00477756 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | -0.00477753 |
| CNTN1 | contactin 1 | -0.00476477 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | -0.00474022 |
| FRMD4B | FERM domain containing 4B | -0.0047376 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00473248 |
| MED13L | mediator complex subunit 13-like | -0.00467832 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | -0.0046588 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | -0.00464271 |
| PYCARD | PYD and CARD domain containing | -0.00464234 |
| TSPYL5 | TSPY-like 5 | -0.00463449 |
| BPI | bactericidal/permeability-increasing protein | -0.00462904 |
| COL10A1 | collagen, type X, alpha 1 | -0.00462327 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | -0.00462266 |
| TMEM260 | transmembrane protein 260 | -0.00462204 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.00462166 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | -0.00461325 |
| PTK2 | protein tyrosine kinase 2 | -0.00458557 |
| HBD | hemoglobin, delta | -0.00458386 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | -0.00457295 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00456251 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.00455774 |
| DMAC2L | distal membrane arm assembly component 2 like | -0.00455602 |
| UPK1B | uroplakin 1B | -0.00454873 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | -0.00454411 |
| CLGN | calmegin | -0.00454217 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | -0.00453036 |
| IRF4 | interferon regulatory factor 4 | -0.00452116 |
| GFRA1 | GDNF family receptor alpha 1 | -0.00451151 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.00450892 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00450215 |
| PUDP | pseudouridine 5'-phosphatase | -0.00449943 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | -0.00449273 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | -0.00448067 |
| CCN2 | cellular communication network factor 2 | -0.00447904 |
| KRT5 | keratin 5, type II | -0.00446891 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa | -0.00445565 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | -0.00445538 |
| EIF1AX | eukaryotic translation initiation factor 1A, X-linked | -0.00445028 |
| CYBB | cytochrome b-245, beta polypeptide | -0.00444798 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.00444746 |
| ARL3 | ADP-ribosylation factor-like 3 | -0.00443859 |
| MIR22HG | MIR22 host gene | -0.0044279 |
| MMP1 | matrix metallopeptidase 1 | -0.00441731 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -0.00441412 |
| ODC1 | ornithine decarboxylase 1 | -0.00441202 |
| SERPINB7 | serpin peptidase inhibitor, clade B (ovalbumin), member 7 | -0.00439964 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | -0.00439952 |
| HOXC4 | homeobox C4 | -0.00439817 |
| ALOX15B | arachidonate 15-lipoxygenase, type B | -0.00439811 |
| MPO | myeloperoxidase | -0.0043981 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | -0.004375 |
| TMEM50B | transmembrane protein 50B | -0.00437456 |
| PFN2 | profilin 2 | -0.00437032 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.00435089 |
| TPBG | trophoblast glycoprotein | -0.00435057 |
| WISP2 | WNT1 inducible signaling pathway protein 2 | -0.00434603 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.0043391 |
| CHGB | chromogranin B | -0.00433606 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00433238 |
| EGLN2 | egl-9 family hypoxia-inducible factor 2 | -0.00430094 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | -0.00429997 |
| RNPS1 | RNA binding protein S1, serine-rich domain | -0.00429375 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta | -0.00427898 |
| ADM | adrenomedullin | -0.00427358 |
| PXDN | peroxidasin | -0.00427271 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.00426484 |
| SLC25A12 | solute carrier family 25 (aspartate/glutamate carrier), member 12 | -0.0042646 |
| ORC4 | origin recognition complex, subunit 4 | -0.00425413 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.00425114 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | -0.00425077 |
| CLEC11A | C-type lectin domain family 11, member A | -0.00424328 |
| PCNA | proliferating cell nuclear antigen | -0.00423522 |
| IL6R | interleukin 6 receptor | -0.00423076 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00422834 |
| HMOX1 | heme oxygenase 1 | -0.00421449 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.00419715 |
| DNALI1 | dynein, axonemal, light intermediate chain 1 | -0.00418887 |
| ZNF91 | zinc finger protein 91 | -0.00418864 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) | -0.00418864 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.00416668 |
| MSRB1 | methionine sulfoxide reductase B1 | -0.00415023 |
| CD22 | CD22 molecule | -0.00415022 |
| RSL24D1 | ribosomal L24 domain containing 1 | -0.0041488 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.00413275 |
| BPIFA1 | BPI fold containing family A, member 1 | -0.00413131 |
| PEG10 | paternally expressed 10 | -0.00412931 |
| MSL1 | male-specific lethal 1 homolog (Drosophila) | -0.00412203 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.00410804 |
| DCUN1D1 | DCN1, defective in cullin neddylation 1, domain containing 1 | -0.00410425 |
