NU-1025-313 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the NU-1025-313 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
ACOT11 acyl-CoA thioesterase 11
ADAM22 ADAM metallopeptidase domain 22
AGFG2 ArfGAP with FG repeats 2
AGRN agrin
ARSA arylsulfatase A
ASCL3 achaete-scute family bHLH transcription factor 3
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
B3GAT3 beta-1,3-glucuronyltransferase 3
BICD2 bicaudal D homolog 2 (Drosophila)
C16ORF59 chromosome 16 open reading frame 59
C21ORF2 chromosome 21 open reading frame 2
C4BPA complement component 4 binding protein, alpha
CA11 carbonic anhydrase XI
CBX2 chromobox homolog 2
CDC14A cell division cycle 14A
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHRM4 cholinergic receptor, muscarinic 4
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DENND3 DENN/MADD domain containing 3
DGCR2 DiGeorge syndrome critical region gene 2
DLEC1 deleted in lung and esophageal cancer 1
DST dystonin
DVL2 dishevelled segment polarity protein 2
ERCC2 excision repair cross-complementation group 2
FBXO38 F-box protein 38
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FXR2 fragile X mental retardation, autosomal homolog 2
FXYD1 FXYD domain containing ion transport regulator 1
GAS7 growth arrest-specific 7
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GRM2 glutamate receptor, metabotropic 2
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HMHA1 histocompatibility (minor) HA-1
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IL11 interleukin 11
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
ITFG2 integrin alpha FG-GAP repeat containing 2
ITGB5 integrin, beta 5
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KCTD13 potassium channel tetramerization domain containing 13
KDM4B lysine (K)-specific demethylase 4B
KHNYN KH and NYN domain containing
KIAA0141 KIAA0141
KRI1 KRI1 homolog (S. cerevisiae)
LGALS8 lectin, galactoside-binding, soluble, 8
LINC00574 long intergenic non-protein coding RNA 574
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
MALT1 MALT1 paracaspase
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MEP1B meprin A, beta
MYL1 myosin, light chain 1, alkali; skeletal, fast
MYL10 myosin, light chain 10, regulatory
MYO1F myosin IF
MYO7A myosin VIIA
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NPAT nuclear protein, ataxia-telangiectasia locus
NR4A1 nuclear receptor subfamily 4, group A, member 1
ODF2 outer dense fiber of sperm tails 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PCGF1 polycomb group ring finger 1
PIEZO2 piezo-type mechanosensitive ion channel component 2
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PKD2L1 polycystic kidney disease 2-like 1
PLEK2 pleckstrin 2
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PRKD3 protein kinase D3
PRSS53 protease, serine, 53
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RBMS2 RNA binding motif, single stranded interacting protein 2
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RPAIN RPA interacting protein
RUNDC3A RUN domain containing 3A
SAP18 Sin3A-associated protein, 18kDa
SBNO2 strawberry notch homolog 2 (Drosophila)
SPTB spectrin, beta, erythrocytic
SPTBN1 spectrin, beta, non-erythrocytic 1
TBC1D30 TBC1 domain family, member 30
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
TCL1A T-cell leukemia/lymphoma 1A
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast)
TMC6 transmembrane channel-like 6
TMEM161A transmembrane protein 161A
TRADD TNFRSF1A-associated via death domain
TRIL TLR4 interactor with leucine-rich repeats
TTC39A tetratricopeptide repeat domain 39A
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
VARS valyl-tRNA synthetase
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WDR91 WD repeat domain 91
ZCCHC24 zinc finger, CCHC domain containing 24
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ADM2 adrenomedullin 2
ALPK1 alpha-kinase 1
ALX3 ALX homeobox 3
AMOT angiomotin
AMOTL2 angiomotin like 2
AMPH amphiphysin
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
AQP8 aquaporin 8
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
ATXN8OS ATXN8 opposite strand (non-protein coding)
BAGE B melanoma antigen
C2 complement component 2
CCBL2 cysteine conjugate-beta lyase 2
CCDC87 coiled-coil domain containing 87
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CHODL chondrolectin
CRYGA crystallin, gamma A
CYB5R2 cytochrome b5 reductase 2
EFCAB1 EF-hand calcium binding domain 1
EGLN3 egl-9 family hypoxia-inducible factor 3
ELOVL4 ELOVL fatty acid elongase 4
FANCF Fanconi anemia, complementation group F
GAS8-AS1 GAS8 antisense RNA 1
GLRA2 glycine receptor, alpha 2
GPX5 glutathione peroxidase 5
GSTA4 glutathione S-transferase alpha 4
HCG4B HLA complex group 4B (non-protein coding)
HOXB9 homeobox B9
HOXD11 homeobox D11
HPX hemopexin
IFI27 interferon, alpha-inducible protein 27
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFNA5 interferon, alpha 5
IHH indian hedgehog
IL13 interleukin 13
ISG15 ISG15 ubiquitin-like modifier
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KDM8 lysine (K)-specific demethylase 8
KIFC3 kinesin family member C3
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KLHL3 kelch-like family member 3
KRT85 keratin 85, type II
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LIN7A lin-7 homolog A (C. elegans)
LINC00339 long intergenic non-protein coding RNA 339
LOC100286895 cell division cycle 27 homolog pseudogene
LOC145678 uncharacterized LOC145678
MMP8 matrix metallopeptidase 8
MNMIP1 manchette microtubule inner protein 1
MSL2 male-specific lethal 2 homolog (Drosophila)
MTERF4 mitochondrial transcription termination factor 4
NAT8B N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene)
NOL12 nucleolar protein 12
NPY6R neuropeptide Y receptor Y6 (pseudogene)
OR52A1 olfactory receptor, family 52, subfamily A, member 1
OR7A17 olfactory receptor, family 7, subfamily A, member 17
PDCD1 programmed cell death 1
PECR peroxisomal trans-2-enoyl-CoA reductase
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
POLI polymerase (DNA directed) iota
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PRSS2 protease, serine, 2 (trypsin 2)
PTPRT protein tyrosine phosphatase, receptor type, T
RAB33A RAB33A, member RAS oncogene family
RASL10A RAS-like, family 10, member A
RDH8 retinol dehydrogenase 8 (all-trans)
ROPN1B rhophilin associated tail protein 1B
RSPH6A radial spoke head 6 homolog A (Chlamydomonas)
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SIGLEC5 sialic acid binding Ig-like lectin 5
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC39A2 solute carrier family 39 (zinc transporter), member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SOX18 SRY (sex determining region Y)-box 18
SPRR1B small proline-rich protein 1B
TEX13B testis expressed 13B
THBS2 thrombospondin 2
TMEM209 transmembrane protein 209
TMPRSS5 transmembrane protease, serine 5
TNNC2 troponin C type 2 (fast)
TSHZ2 teashirt zinc finger homeobox 2
TSPAN7 tetraspanin 7
UBTD1 ubiquitin domain containing 1
UNC93B1 unc-93 homolog B1 (C. elegans)
VASP vasodilator-stimulated phosphoprotein
VEZT vezatin, adherens junctions transmembrane protein
VIM vimentin
VSIG4 V-set and immunoglobulin domain containing 4
ZC4H2 zinc finger, C4H2 domain containing
ZNF211 zinc finger protein 211
ZNF286A zinc finger protein 286A
ZNF358 zinc finger protein 358