NU-1025-608 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the NU-1025-608 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ACACA acetyl-CoA carboxylase alpha
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
AJAP1 adherens junctions associated protein 1
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARRB2 arrestin, beta 2
ATG4B autophagy related 4B, cysteine peptidase
ATXN8OS ATXN8 opposite strand (non-protein coding)
AXIN1 axin 1
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C2ORF72 chromosome 2 open reading frame 72
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CCDC40 coiled-coil domain containing 40
CCNT1 cyclin T1
CD84 CD84 molecule
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CIR1 corepressor interacting with RBPJ, 1
COX15 cytochrome c oxidase assembly homolog 15 (yeast)
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CTAGE9 CTAGE family, member 9
CTC1 CTS telomere maintenance complex component 1
CTIF CBP80/20-dependent translation initiation factor
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DCP1A decapping mRNA 1A
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
DYSF dysferlin
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ELF4 E74-like factor 4 (ets domain transcription factor)
FAM153A family with sequence similarity 153, member A
FBXO38 F-box protein 38
FKBP8 FK506 binding protein 8, 38kDa
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FRMD8 FERM domain containing 8
GAB1 GRB2-associated binding protein 1
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GFOD2 glucose-fructose oxidoreductase domain containing 2
GJB3 gap junction protein, beta 3, 31kDa
GMIP GEM interacting protein
GRK6 G protein-coupled receptor kinase 6
GRM1 glutamate receptor, metabotropic 1
GYPC glycophorin C (Gerbich blood group)
HDC histidine decarboxylase
HOXA7 homeobox A7
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
HUS1 HUS1 checkpoint homolog (S. pombe)
IGKC immunoglobulin kappa constant
IL7R interleukin 7 receptor
KDM4B lysine (K)-specific demethylase 4B
LMAN1 lectin, mannose-binding, 1
LPAR1 lysophosphatidic acid receptor 1
MAGOH2P mago-nashi homolog 2, pseudogene
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MARC1 mitochondrial amidoxime reducing component 1
MAST2 microtubule associated serine/threonine kinase 2
MTF1 metal-regulatory transcription factor 1
MZF1 myeloid zinc finger 1
NEU3 sialidase 3 (membrane sialidase)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NUPL2 nucleoporin like 2
OR10H3 olfactory receptor, family 10, subfamily H, member 3
OSBPL7 oxysterol binding protein-like 7
PCGF1 polycomb group ring finger 1
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLK3 polo-like kinase 3
PRB1 proline-rich protein BstNI subfamily 1
PRKCA protein kinase C, alpha
PRPF18 pre-mRNA processing factor 18
RANBP10 RAN binding protein 10
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
SBNO2 strawberry notch homolog 2 (Drosophila)
SGSH N-sulfoglucosamine sulfohydrolase
SH3GL3 SH3-domain GRB2-like 3
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SIL1 SIL1 nucleotide exchange factor
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLPI secretory leukocyte peptidase inhibitor
SPN sialophorin
STAB1 stabilin 1
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TGM5 transglutaminase 5
TP53I11 tumor protein p53 inducible protein 11
TPMT thiopurine S-methyltransferase
TREX1 three prime repair exonuclease 1
TRPA1 transient receptor potential cation channel, subfamily A, member 1
UBE4B ubiquitination factor E4B
ULK2 unc-51 like autophagy activating kinase 2
USP2 ubiquitin specific peptidase 2
WDTC1 WD and tetratricopeptide repeats 1
WWC2 WW and C2 domain containing 2
ZFP36 ZFP36 ring finger protein
ZNF428 zinc finger protein 428
ZNF668 zinc finger protein 668

decreased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ABHD3 abhydrolase domain containing 3
ADGRB1 adhesion G protein-coupled receptor B1
ADGRE5 adhesion G protein-coupled receptor E5
ADM2 adrenomedullin 2
AIM2 absent in melanoma 2
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALX3 ALX homeobox 3
ANKRD36B ankyrin repeat domain 36B
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ARSE arylsulfatase E (chondrodysplasia punctata 1)
AURKC aurora kinase C
BAGE B melanoma antigen
C4ORF29 chromosome 4 open reading frame 29
CAPG capping protein (actin filament), gelsolin-like
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBX8 chromobox homolog 8
CCDC7 coiled-coil domain containing 7
CCDC70 coiled-coil domain containing 70
CCK cholecystokinin
CCNO cyclin O
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD5 CD5 molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CHKB choline kinase beta
CLEC4E C-type lectin domain family 4, member E
CPB1 carboxypeptidase B1 (tissue)
CST4 cystatin S
CUBN cubilin (intrinsic factor-cobalamin receptor)
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DENND4C DENN/MADD domain containing 4C
DEPDC5 DEP domain containing 5
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
DPEP1 dipeptidase 1 (renal)
DRP2 dystrophin related protein 2
DSCAM Down syndrome cell adhesion molecule
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
FBXO31 F-box protein 31
FOXO3 forkhead box O3
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GAREM GRB2 associated, regulator of MAPK1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR35 G protein-coupled receptor 35
GRIP2 glutamate receptor interacting protein 2
H2AFY2 H2A histone family, member Y2
HIST1H3G histone cluster 1, H3g
HIST1H4E histone cluster 1, H4e
HPX hemopexin
IFNA4 interferon, alpha 4
IL12RB1 interleukin 12 receptor, beta 1
IL36RN interleukin 36 receptor antagonist
INSL4 insulin-like 4 (placenta)
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KLHL36 kelch-like family member 36
KRI1 KRI1 homolog (S. cerevisiae)
KRT75 keratin 75, type II
LARP6 La ribonucleoprotein domain family, member 6
LOC100272216 uncharacterized LOC100272216
LPAR3 lysophosphatidic acid receptor 3
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
MFGE8 milk fat globule-EGF factor 8 protein
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
NELL2 NEL-like 2 (chicken)
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NLRX1 NLR family member X1
NPY1R neuropeptide Y receptor Y1
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
POGLUT1 protein O-glucosyltransferase 1
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
POMT2 protein-O-mannosyltransferase 2
PPAN peter pan homolog (Drosophila)
PPP1R26 protein phosphatase 1, regulatory subunit 26
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene)
RCAN2 regulator of calcineurin 2
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF141 ring finger protein 141
SCAI suppressor of cancer cell invasion
SELL selectin L
SLC17A4 solute carrier family 17, member 4
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMCO4 single-pass membrane protein with coiled-coil domains 4
SND1-IT1 SND1 intronic transcript 1
SNX10 sorting nexin 10
SUSD4 sushi domain containing 4
TM6SF1 transmembrane 6 superfamily member 1
TMEM209 transmembrane protein 209
TRBV10-2 T cell receptor beta variable 10-2
TREM2 triggering receptor expressed on myeloid cells 2
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSPAN32 tetraspanin 32
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
XYLT2 xylosyltransferase II
ZBED1 zinc finger, BED-type containing 1
ZBTB16 zinc finger and BTB domain containing 16
ZNF219 zinc finger protein 219
ZNF652 zinc finger protein 652