NUCKS1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description nuclear casein kinase and cyclin-dependent kinase substrate 1|This gene encodes a nuclear protein that is highly conserved in vertebrates. The conserved regions of the protein contain several consensus phosphorylation sites for casein kinase II and cyclin-dependent kinases, two putative nuclear localization signals, and a basic DNA-binding domain. It is phosphorylated in vivo by Cdk1 during mitosis of the cell cycle. [provided by RefSeq, Aug 2010] (NCBI Entrez Gene Database, 64710)
External Link https://ncbi.nlm.nih.gov/gene/64710
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Genes

499 genes differentially expressed following the NUCKS1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
LCN2 lipocalin 2 0.0105476
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.0100454
HTRA1 HtrA serine peptidase 1 0.00913726
PLBD1 phospholipase B domain containing 1 0.00906352
PITX3 paired-like homeodomain 3 0.008564
CD9 CD9 molecule 0.00834326
QPCT glutaminyl-peptide cyclotransferase 0.00816764
TFPI2 tissue factor pathway inhibitor 2 0.00748643
TUBB2B tubulin, beta 2B class IIb 0.00740258
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.00735202
PRUNE2 prune homolog 2 (Drosophila) 0.00730566
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.00728908
SCG5 secretogranin V 0.00727388
ADD3 adducin 3 (gamma) 0.00722664
MCOLN1 mucolipin 1 0.00718857
FAM171A1 family with sequence similarity 171, member A1 0.00711879
C5AR1 complement component 5a receptor 1 0.00709514
CXCL3 chemokine (C-X-C motif) ligand 3 0.00680808
DDIT4 DNA-damage-inducible transcript 4 0.00680657
PF4 platelet factor 4 0.00677901
CXCL2 chemokine (C-X-C motif) ligand 2 0.00674852
JCHAIN joining chain of multimeric IgA and IgM 0.00661191
ALOX5 arachidonate 5-lipoxygenase 0.00660353
MSLN mesothelin 0.00658344
DIRAS3 DIRAS family, GTP-binding RAS-like 3 0.0064962
BPHL biphenyl hydrolase-like (serine hydrolase) 0.00649162
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 0.006449
NPC2 Niemann-Pick disease, type C2 0.00640982
MBNL2 muscleblind-like splicing regulator 2 0.00639497
COCH cochlin 0.00634896
ALCAM activated leukocyte cell adhesion molecule 0.00634303
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.00632361
UROD uroporphyrinogen decarboxylase 0.00628315
DIPK1A divergent protein kinase domain 1A 0.00620364
HSPA2 heat shock 70kDa protein 2 0.00618703
ENO2 enolase 2 (gamma, neuronal) 0.00598021
CLC Charcot-Leyden crystal galectin 0.00592261
GDF15 growth differentiation factor 15 0.00589777
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase 0.00589392
NPTX2 neuronal pentraxin II 0.00589237
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.00587202
CXCR4 chemokine (C-X-C motif) receptor 4 0.00574312
CLDN3 claudin 3 0.00571719
LEFTY1 left-right determination factor 1 0.00566144
WNT5B wingless-type MMTV integration site family, member 5B 0.00565492
KRAS Kirsten rat sarcoma viral oncogene homolog 0.00565178
ACP3 acid phosphatase 3 0.00564423
SV2A synaptic vesicle glycoprotein 2A 0.0056315
PRAME preferentially expressed antigen in melanoma 0.00555274
TUBB2A tubulin, beta 2A class IIa 0.00553455
DEFB1 defensin, beta 1 0.00542063
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog 0.00541301
LYPD1 LY6/PLAUR domain containing 1 0.00538739
IFI6 interferon, alpha-inducible protein 6 0.00538396
PCCA propionyl CoA carboxylase, alpha polypeptide 0.00538276
CRELD2 cysteine-rich with EGF-like domains 2 0.00537969
MAL mal, T-cell differentiation protein 0.00536275
TP53I3 tumor protein p53 inducible protein 3 0.00535454
ZNF395 zinc finger protein 395 0.00533535
C9ORF16 chromosome 9 open reading frame 16 0.00531647
MT1X metallothionein 1X 0.00530472
TUBA1A tubulin, alpha 1a 0.00530098
TPSAB1 tryptase alpha/beta 1 0.0052878
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 0.00527539
SC5D sterol-C5-desaturase 0.00526996
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 0.00525801
SCN3A sodium channel, voltage gated, type III alpha subunit 0.00525171
FPR1 formyl peptide receptor 1 0.00524281
SPAG16 sperm associated antigen 16 0.00517399
PTK2B protein tyrosine kinase 2 beta 0.00514609
PDGFC platelet derived growth factor C 0.0051271
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00511788
SIRT3 sirtuin 3 0.00510374
C10ORF10 chromosome 10 open reading frame 10 0.00506722
RHOB ras homolog family member B 0.00506092
GCA grancalcin, EF-hand calcium binding protein 0.00505623
NAMPT nicotinamide phosphoribosyltransferase 0.00504451
SRPX sushi-repeat containing protein, X-linked 0.00502133
GMPR guanosine monophosphate reductase 0.00500691
FCN1 ficolin (collagen/fibrinogen domain containing) 1 0.00489574
FOXG1 forkhead box G1 0.00488538
ZFP36L1 ZFP36 ring finger protein-like 1 0.00487055
TRIB2 tribbles pseudokinase 2 0.00487009
ACSM3 acyl-CoA synthetase medium-chain family member 3 0.00485279
PHACTR1 phosphatase and actin regulator 1 0.00484808
RNF167 ring finger protein 167 0.00483625
MUC4 mucin 4, cell surface associated 0.00479872
MDK midkine (neurite growth-promoting factor 2) 0.0047745
JPT2 Jupiter microtubule associated homolog 2 0.0047615
GNAS GNAS complex locus 0.00474467
PFKM phosphofructokinase, muscle 0.00473685
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 0.00471281
KLK3 kallikrein-related peptidase 3 0.0047068
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00469558
RNF144A ring finger protein 144A 0.00468781
CIAO3 cytosolic iron-sulfur assembly component 3 0.00468302
AQP9 aquaporin 9 0.00465878
NOSIP nitric oxide synthase interacting protein 0.00465673
GLOD4 glyoxalase domain containing 4 0.00465518
ARMCX2 armadillo repeat containing, X-linked 2 0.00464464
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 0.00463645
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.00463496
SYT11 synaptotagmin XI 0.00462215
GSTM3 glutathione S-transferase mu 3 (brain) 0.0046128
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.0045991
DPEP1 dipeptidase 1 (renal) 0.00457304
BHLHE41 basic helix-loop-helix family, member e41 0.00455361
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 0.00453187
TXNDC9 thioredoxin domain containing 9 0.0045236
AKAP12 A kinase (PRKA) anchor protein 12 0.00452265
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00451947
MOK MOK protein kinase 0.00451742
PARD3 par-3 family cell polarity regulator 0.00451418
MX1 MX dynamin-like GTPase 1 0.00449248
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.00448716
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 0.00447346
RNASE6 ribonuclease, RNase A family, k6 0.00447109
PRKCI protein kinase C, iota 0.0044647
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 0.0044501
LST1 leukocyte specific transcript 1 0.00444506
ACP5 acid phosphatase 5, tartrate resistant 0.00443723
LEPROT leptin receptor overlapping transcript 0.00442412
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 0.00442235
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.00440867
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.00439658
EPHB2 EPH receptor B2 0.00439376
GSTZ1 glutathione S-transferase zeta 1 0.0043899
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.00436505
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.00435016
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 0.00433148
PNMA8A PNMA family member 8A 0.00431307
PRKCA protein kinase C, alpha 0.0043074
S100A12 S100 calcium binding protein A12 0.00429873
GADD45A growth arrest and DNA-damage-inducible, alpha 0.00428886
AUTS2 autism susceptibility candidate 2 0.00427897
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 0.00425546
NMU neuromedin U 0.00424644
MT1G metallothionein 1G 0.00423896
OLFM4 olfactomedin 4 0.00422208
PTPRO protein tyrosine phosphatase, receptor type, O 0.00421799
PRKD1 protein kinase D1 0.00420142
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 0.00420124
BMP7 bone morphogenetic protein 7 0.0041878
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.00418326
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.00417727
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 0.00417029
LRRC17 leucine rich repeat containing 17 0.00414326
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 0.004142
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 0.00413829
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.0041345
CRYM crystallin, mu 0.00411434
WBP5 WW domain binding protein 5 0.00411279
PENK proenkephalin 0.00409904
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 0.00408937
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 0.00408917
WDR13 WD repeat domain 13 0.00406251
VCAM1 vascular cell adhesion molecule 1 0.00405843
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.00405724
AOC1 amine oxidase, copper containing 1 0.00405407
DLK1 delta-like 1 homolog (Drosophila) 0.00404972
MT1HL1 metallothionein 1H-like 1 0.00404356
AK4 adenylate kinase 4 0.00402918
COL9A2 collagen, type IX, alpha 2 0.00401874
WDR45 WD repeat domain 45 0.00400857
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 0.00400742
FOS FBJ murine osteosarcoma viral oncogene homolog 0.00400585
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 0.00397619
ISOC2 isochorismatase domain containing 2 0.00396656
COL18A1 collagen, type XVIII, alpha 1 0.00395943
MLF1 myeloid leukemia factor 1 0.00395424
DEFA4 defensin, alpha 4, corticostatin 0.00394605
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.00394072
IL1R1 interleukin 1 receptor, type I 0.00393128
TCL1A T-cell leukemia/lymphoma 1A 0.00393027
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial 0.00392324
CLGN calmegin 0.00392055
DACH1 dachshund family transcription factor 1 0.0039201
PCDH9 protocadherin 9 0.00391162
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 0.00390802
KRCC1 lysine-rich coiled-coil 1 0.00389495
RAP2A RAP2A, member of RAS oncogene family 0.00389199
H1-0 H1.0 linker histone 0.00388901
MSRB1 methionine sulfoxide reductase B1 0.00387703
ZIC1 Zic family member 1 0.0038715
CDK14 cyclin-dependent kinase 14 0.00386873
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase 0.00386447
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 0.00385215
YPEL1 yippee-like 1 (Drosophila) 0.00385117
QPRT quinolinate phosphoribosyltransferase 0.0038472
HIST3H2A histone cluster 3, H2a 0.00384444
CREBL2 cAMP responsive element binding protein-like 2 0.00383767
RAI14 retinoic acid induced 14 0.00383179
RRBP1 ribosome binding protein 1 0.00382725
RCAN1 regulator of calcineurin 1 0.0038168
BCAS3 breast carcinoma amplified sequence 3 0.00381561
BCHE butyrylcholinesterase 0.00381324
BPI bactericidal/permeability-increasing protein 0.00380695
MARCH2 membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase 0.00380592
FGR FGR proto-oncogene, Src family tyrosine kinase 0.00379687
ZBTB16 zinc finger and BTB domain containing 16 0.00379049
ZNF91 zinc finger protein 91 0.00378998
EMX2 empty spiracles homeobox 2 0.00377343
G0S2 G0/G1 switch 2 0.00376968
ACP6 acid phosphatase 6, lysophosphatidic 0.00376615
ACOT9 acyl-CoA thioesterase 9 0.00376337
ZSCAN18 zinc finger and SCAN domain containing 18 0.00376276
RNF43 ring finger protein 43 0.003759
TMEM8A transmembrane protein 8A 0.00375409
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.00375362
PHYH phytanoyl-CoA 2-hydroxylase 0.00374755
NAV2 neuron navigator 2 0.0037468
TRAF4 TNF receptor-associated factor 4 0.0037465
TCEAL1 transcription elongation factor A (SII)-like 1 0.00373459
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 0.00371973
PLEKHA5 pleckstrin homology domain containing, family A member 5 0.00371953
TARP TCR gamma alternate reading frame protein 0.00371502
TWIST1 twist family bHLH transcription factor 1 0.00371442
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00371053
ACTN1 actinin, alpha 1 0.00370621
ZNF274 zinc finger protein 274 0.00370594
STYXL1 serine/threonine/tyrosine interacting-like 1 0.00368654
DDAH2 dimethylarginine dimethylaminohydrolase 2 0.00368304
CTNS cystinosin, lysosomal cystine transporter 0.00368107
BCR breakpoint cluster region 0.00367681
RAB13 RAB13, member RAS oncogene family 0.00367575
DHCR24 24-dehydrocholesterol reductase 0.00366879
THBS4 thrombospondin 4 0.00366067
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.00365904
SURF1 surfeit 1 0.00365784
MUC16 mucin 16, cell surface associated 0.00365692
ARG1 arginase 1 0.00365561
RTN1 reticulon 1 0.00365046
KDM3A lysine (K)-specific demethylase 3A 0.0036485
OSBPL8 oxysterol binding protein-like 8 0.00364779
ADGRG1 adhesion G protein-coupled receptor G1 0.00364088
TM7SF2 transmembrane 7 superfamily member 2 0.0036347
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 0.00363457
TREM1 triggering receptor expressed on myeloid cells 1 0.00363253
CUX2 cut-like homeobox 2 0.00362801
EFNB2 ephrin-B2 0.00362053
ARL4C ADP-ribosylation factor-like 4C 0.00361628
KLK2 kallikrein-related peptidase 2 0.00360652
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 0.00360397
TRIM8 tripartite motif containing 8 0.00360288
ERCC1 excision repair cross-complementation group 1 0.00359965
CEP70 centrosomal protein 70kDa 0.00359233
RTN3 reticulon 3 0.00359082
BIN1 bridging integrator 1 0.00358472
CTBS chitobiase, di-N-acetyl- 0.00357725

decreased expression

Symbol Name Standardized Value
CLU clusterin -0.0133298
MAP7 microtubule-associated protein 7 -0.0114552
MTUS1 microtubule associated tumor suppressor 1 -0.00915394
MGP matrix Gla protein -0.00893872
POSTN periostin, osteoblast specific factor -0.00881152
CAV1 caveolin 1, caveolae protein, 22kDa -0.0082138
ADAMDEC1 ADAM-like, decysin 1 -0.00820895
CAV2 caveolin 2 -0.00805797
PBX1 pre-B-cell leukemia homeobox 1 -0.00802279
MAOB monoamine oxidase B -0.00792834
ITM2A integral membrane protein 2A -0.00792123
OLFM1 olfactomedin 1 -0.00768475
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 -0.00764444
STOM stomatin -0.00757064
PHACTR2 phosphatase and actin regulator 2 -0.00752828
PCLAF PCNA clamp associated factor -0.00750514
TFRC transferrin receptor -0.00748065
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -0.00724617
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.00709309
CCL19 chemokine (C-C motif) ligand 19 -0.00689153
RDX radixin -0.00685417
NPR3 natriuretic peptide receptor 3 -0.0068119
REEP1 receptor accessory protein 1 -0.00672282
CHI3L2 chitinase 3-like 2 -0.00666873
FGFR2 fibroblast growth factor receptor 2 -0.00664233
PEG3 paternally expressed 3 -0.00664017
MDFIC MyoD family inhibitor domain containing -0.00659488
KRT7 keratin 7, type II -0.00656776
CD44 CD44 molecule (Indian blood group) -0.0065676
PMP22 peripheral myelin protein 22 -0.00656195
SCGB2A2 secretoglobin, family 2A, member 2 -0.00652718
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00647342
SPARCL1 SPARC-like 1 (hevin) -0.00643709
MALL mal, T-cell differentiation protein-like -0.00638403
LMO2 LIM domain only 2 (rhombotin-like 1) -0.00637953
EFHD1 EF-hand domain family, member D1 -0.00635128
PDE4B phosphodiesterase 4B, cAMP-specific -0.00618856
PTK2 protein tyrosine kinase 2 -0.00612628
PCNA proliferating cell nuclear antigen -0.00602258
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.00601342
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -0.00599014
ASPN asporin -0.0059757
CRIP1 cysteine-rich protein 1 (intestinal) -0.00597232
PRNP prion protein -0.00596332
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -0.0059316
HSPB8 heat shock 22kDa protein 8 -0.00590873
PIP prolactin-induced protein -0.00584268
HACD3 3-hydroxyacyl-CoA dehydratase 3 -0.00583871
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 -0.00583542
ACTA2 actin, alpha 2, smooth muscle, aorta -0.00583109
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00572713
TNC tenascin C -0.00568922
CPS1 carbamoyl-phosphate synthase 1, mitochondrial -0.00567084
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00566394
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 -0.00563519
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 -0.00557345
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 -0.00553737
DKK2 dickkopf WNT signaling pathway inhibitor 2 -0.00552687
C4BPA complement component 4 binding protein, alpha -0.00544487
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) -0.00544417
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.00541437
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.0054057
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein -0.00535328
PDZK1 PDZ domain containing 1 -0.00528448
SCGB1D2 secretoglobin, family 1D, member 2 -0.00526027
NR2F1 nuclear receptor subfamily 2, group F, member 1 -0.00523912
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 -0.00523695
RBPMS RNA binding protein with multiple splicing -0.00522593
RGS13 regulator of G-protein signaling 13 -0.0052194
HHEX hematopoietically expressed homeobox -0.00521275
LUM lumican -0.00520784
TYMS thymidylate synthetase -0.00518204
ADIRF adipogenesis regulatory factor -0.00517846
COL5A2 collagen, type V, alpha 2 -0.00515332
ASPH aspartate beta-hydroxylase -0.0051523
RFTN1 raftlin, lipid raft linker 1 -0.00514533
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.00511743
TAGLN transgelin -0.00511218
RAB25 RAB25, member RAS oncogene family -0.00508309
BMP4 bone morphogenetic protein 4 -0.00508149
CFH complement factor H -0.00507966
PROM1 prominin 1 -0.00507232
DKFZP586I1420 uncharacterized protein DKFZp586I1420 -0.00505482
TFDP1 transcription factor Dp-1 -0.00499093
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta -0.00499012
COL3A1 collagen, type III, alpha 1 -0.00498655
RAB1A RAB1A, member RAS oncogene family -0.00496692
TPM2 tropomyosin 2 (beta) -0.00496316
ADGRF5 adhesion G protein-coupled receptor F5 -0.00491018
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) -0.00486444
PPP1R3C protein phosphatase 1, regulatory subunit 3C -0.00485979
RGCC regulator of cell cycle -0.0048407
SAP30 Sin3A-associated protein, 30kDa -0.00483972
CALD1 caldesmon 1 -0.00482896
KRT17 keratin 17, type I -0.0048231
CBX1 chromobox homolog 1 -0.00481849
PNN pinin, desmosome associated protein -0.00481765
KCNK1 potassium channel, two pore domain subfamily K, member 1 -0.00480268
RHOA ras homolog family member A -0.00479668
SUB1 SUB1 homolog (S. cerevisiae) -0.00476332
RGS5 regulator of G-protein signaling 5 -0.00473322
TENT4A terminal nucleotidyltransferase 4A -0.00473199
FOXF1 forkhead box F1 -0.0047264
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -0.00472429
NDP Norrie disease (pseudoglioma) -0.00470889
TOX3 TOX high mobility group box family member 3 -0.00469239
LYZ lysozyme -0.00468848
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.00467044
LIMCH1 LIM and calponin homology domains 1 -0.00466819
MMP12 matrix metallopeptidase 12 -0.00465275
TRAM1 translocation associated membrane protein 1 -0.00463431
HOPX HOP homeobox -0.00463181
HSPA4L heat shock 70kDa protein 4-like -0.00461445
PALLD palladin, cytoskeletal associated protein -0.00460894
HOXC6 homeobox C6 -0.00460589
STK17A serine/threonine kinase 17a -0.00459979
LRP2 low density lipoprotein receptor-related protein 2 -0.00459813
LGALS2 lectin, galactoside-binding, soluble, 2 -0.00458788
SDC2 syndecan 2 -0.00457958
MREG melanoregulin -0.00457948
DUSP5 dual specificity phosphatase 5 -0.00457168
CXCL9 chemokine (C-X-C motif) ligand 9 -0.00454073
ARHGAP29 Rho GTPase activating protein 29 -0.0045097
CCNB1 cyclin B1 -0.00450104
ENPEP glutamyl aminopeptidase (aminopeptidase A) -0.00448389
CYB5R2 cytochrome b5 reductase 2 -0.00448184
FNBP1 formin binding protein 1 -0.00447294
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -0.00447042
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 -0.00445671
SRSF1 serine/arginine-rich splicing factor 1 -0.00445034
PITX1 paired-like homeodomain 1 -0.00444887
ATXN1 ataxin 1 -0.00442968
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.00442692
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00442252
TFF3 trefoil factor 3 (intestinal) -0.0044224
COL15A1 collagen, type XV, alpha 1 -0.00442131
TENT5A terminal nucleotidyltransferase 5A -0.00442083
CCT3 chaperonin containing TCP1, subunit 3 (gamma) -0.00441871
SCD5 stearoyl-CoA desaturase 5 -0.00441639
AKAP8 A kinase (PRKA) anchor protein 8 -0.00440543
GOLM1 golgi membrane protein 1 -0.00440081
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00438176
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.00437415
FGF13 fibroblast growth factor 13 -0.00437083
GCH1 GTP cyclohydrolase 1 -0.00436053
CALCRL calcitonin receptor-like -0.00435698
UBE2G2 ubiquitin-conjugating enzyme E2G 2 -0.00435303
HSPE1 heat shock 10kDa protein 1 -0.00434935
MSX1 msh homeobox 1 -0.00434313
TSPO translocator protein (18kDa) -0.00434245
RHOH ras homolog family member H -0.00433816
CTSC cathepsin C -0.00433726
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 -0.00433356
C4BPB complement component 4 binding protein, beta -0.00432898
CLCA4 chloride channel accessory 4 -0.00432782
GNPAT glyceronephosphate O-acyltransferase -0.00432687
ANOS1 anosmin 1 -0.00432326
CEP43 centrosomal protein 43 -0.00431605
HBB hemoglobin, beta -0.00429853
C8ORF33 chromosome 8 open reading frame 33 -0.00429065
PCSK6 proprotein convertase subtilisin/kexin type 6 -0.00428734
AHCYL2 adenosylhomocysteinase-like 2 -0.00428615
MAB21L2 mab-21-like 2 (C. elegans) -0.00428576
DSG3 desmoglein 3 -0.00427599
NR1H3 nuclear receptor subfamily 1, group H, member 3 -0.0042682
CFD complement factor D (adipsin) -0.00426634
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 -0.00425416
TMPRSS4 transmembrane protease, serine 4 -0.00424484
DPP8 dipeptidyl-peptidase 8 -0.00424055
CRABP2 cellular retinoic acid binding protein 2 -0.00424032
SCRG1 stimulator of chondrogenesis 1 -0.00423678
MAN2A1 mannosidase, alpha, class 2A, member 1 -0.0042087
TXN thioredoxin -0.00420358
HSPA4 heat shock 70kDa protein 4 -0.00420285
NTS neurotensin -0.00418708
NIT1 nitrilase 1 -0.00417744
NFASC neurofascin -0.00417519
TCTA T-cell leukemia translocation altered -0.00417118
CD99 CD99 molecule -0.00416207
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon -0.00414618
KIAA0040 KIAA0040 -0.00413657
PNISR PNN-interacting serine/arginine-rich protein -0.00412827
TMEM204 transmembrane protein 204 -0.00412648
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase -0.00411973
ORM1 orosomucoid 1 -0.00411721
MTCL1 microtubule crosslinking factor 1 -0.00410765
NCK1 NCK adaptor protein 1 -0.00409741
GAS1 growth arrest-specific 1 -0.00409505
EGLN3 egl-9 family hypoxia-inducible factor 3 -0.00409218
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 -0.00407315
SRSF10 serine/arginine-rich splicing factor 10 -0.00406301
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -0.00404869
SFTPB surfactant protein B -0.00404674
APOB apolipoprotein B -0.00403846
ADGRG2 adhesion G protein-coupled receptor G2 -0.00399911
CCN2 cellular communication network factor 2 -0.00397364
PHIP pleckstrin homology domain interacting protein -0.0039705
EREG epiregulin -0.00396998
DLG1 discs, large homolog 1 (Drosophila) -0.00396923
CHN1 chimerin 1 -0.00395496
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.00395308
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 -0.00394974
CDH5 cadherin 5, type 2 (vascular endothelium) -0.00394589
CKS1B CDC28 protein kinase regulatory subunit 1B -0.00394315
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.00393977
GRB14 growth factor receptor-bound protein 14 -0.00393974
NNMT nicotinamide N-methyltransferase -0.00393525
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 -0.00393292
PROCR protein C receptor, endothelial -0.0039296
PIR pirin (iron-binding nuclear protein) -0.0039232
TP63 tumor protein p63 -0.00392066
TPM4 tropomyosin 4 -0.00392006
FABP4 fatty acid binding protein 4, adipocyte -0.00391827
HOXA11 homeobox A11 -0.00391757
FHL2 four and a half LIM domains 2 -0.00390459
TIMP1 TIMP metallopeptidase inhibitor 1 -0.00389815
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -0.00389683
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme -0.00389341
MFAP4 microfibrillar-associated protein 4 -0.00388706
ZNF207 zinc finger protein 207 -0.00388609
KBTBD11 kelch repeat and BTB (POZ) domain containing 11 -0.00387743
FASTKD3 FAST kinase domains 3 -0.00386977
AGR2 anterior gradient 2 -0.00386845
TBX3 T-box 3 -0.00386735
EZR ezrin -0.00386624
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 -0.00386572
PAXBP1 PAX3 and PAX7 binding protein 1 -0.00385723
DUSP12 dual specificity phosphatase 12 -0.00385332
PRPF3 pre-mRNA processing factor 3 -0.00384843
PXMP2 peroxisomal membrane protein 2, 22kDa -0.00383333
KRT23 keratin 23, type I -0.00383135
SETD5 SET domain containing 5 -0.00382989
DRAM1 DNA-damage regulated autophagy modulator 1 -0.00382847
CARTPT CART prepropeptide -0.00382616
PUDP pseudouridine 5'-phosphatase -0.00382518
GREM1 gremlin 1, DAN family BMP antagonist -0.0038239
HAPLN1 hyaluronan and proteoglycan link protein 1 -0.00381269
GSTA4 glutathione S-transferase alpha 4 -0.00381225
TMEM70 transmembrane protein 70 -0.00381071
RIDA reactive intermediate imine deaminase A homolog -0.00380402
CKS2 CDC28 protein kinase regulatory subunit 2 -0.00379345
LPCAT1 lysophosphatidylcholine acyltransferase 1 -0.00378541
PLPP2 phospholipid phosphatase 2 -0.00378273
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.00378203
ZNF532 zinc finger protein 532 -0.00378022
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.00376912
EN1 engrailed homeobox 1 -0.00376854
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.00376754
RFX5 regulatory factor X, 5 (influences HLA class II expression) -0.00376501
RAN RAN, member RAS oncogene family -0.00376467