NUDT7 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description nudix (nucleoside diphosphate linked moiety X)-type motif 7|The protein encoded by this gene is a member of the Nudix hydrolase family. Nudix hydrolases eliminate potentially toxic nucleotide metabolites from the cell and regulate the concentrations and availability of many different nucleotide substrates, cofactors, and signaling molecules. Alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. [provided by RefSeq, Aug 2011] (NCBI Entrez Gene Database, 283927)
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Genes

328 genes differentially expressed following the NUDT7 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
NPPC natriuretic peptide C 3.70398
IL5RA interleukin 5 receptor, alpha 3.70398
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 3.70398
AIFM3 apoptosis-inducing factor, mitochondrion-associated, 3 3.70398
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 3.70398
ARHGAP36 Rho GTPase activating protein 36 3.70398
OLIG1 oligodendrocyte transcription factor 1 3.70398
SIGLEC7 sialic acid binding Ig-like lectin 7 3.70398
ASB17 ankyrin repeat and SOCS box containing 17 3.70398
OLFM4 olfactomedin 4 3.70398
RASSF10 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10 3.70398
PNMA5 paraneoplastic Ma antigen family member 5 3.70398
OR7A10 olfactory receptor, family 7, subfamily A, member 10 3.70398
HEATR9 HEAT repeat containing 9 3.70398
CD19 CD19 molecule 3.70398
SPINK4 serine peptidase inhibitor, Kazal type 4 3.70398
TMEM176A transmembrane protein 176A 3.70398
FABP1 fatty acid binding protein 1, liver 3.70398
PCDHB6 protocadherin beta 6 3.70398
SLC35G5 solute carrier family 35, member G5 3.70398
OR2B2 olfactory receptor, family 2, subfamily B, member 2 3.70398
REN renin 3.70398
RFPL3 ret finger protein-like 3 3.70398
NRROS negative regulator of reactive oxygen species 3.70398
THSD1 thrombospondin, type I, domain containing 1 3.70398
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) 3.70398
HIC1 hypermethylated in cancer 1 3.70398
CFAP53 cilia and flagella associated protein 53 3.70398
CLCF1 cardiotrophin-like cytokine factor 1 3.70398
NPB neuropeptide B 3.70398
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 3.70398
PRSS21 protease, serine, 21 (testisin) 3.70398
FAM81B family with sequence similarity 81, member B 3.70398
TMC2 transmembrane channel-like 2 3.70398
PGBD4 piggyBac transposable element derived 4 3.70398
CA7 carbonic anhydrase VII 3.70398
ADAMTSL5 ADAMTS-like 5 3.70398
ADAMTSL2 ADAMTS-like 2 3.70398
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 3.70398
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2 3.70398
ZNF324B zinc finger protein 324B 3.70398
F2 coagulation factor II (thrombin) 3.70398
MEIKIN meiotic kinetochore factor 3.70398
SPMIP9 sperm microtubule inner protein 9 3.70398
NR2F2 nuclear receptor subfamily 2, group F, member 2 3.70398
ADGRE3 adhesion G protein-coupled receptor E3 3.70398
PNMA6E PNMA family member 6E 3.70398
DNAAF8 dynein axonemal assembly factor 8 3.70398
DERPC DERPC proline and glycine rich nuclear protein 3.70398
RAX2 retina and anterior neural fold homeobox 2 3.70398
SCEL sciellin 3.70398
GPR35 G protein-coupled receptor 35 3.70398
RHCG Rh family, C glycoprotein 3.70398
SMLR1 small leucine-rich protein 1 3.70398
LRRC70 leucine rich repeat containing 70 3.70398
SHC4 SHC (Src homology 2 domain containing) family, member 4 3.70398
MSANTD5 Myb/SANT DNA binding domain containing 5 3.70398
DIPK2B divergent protein kinase domain 2B 3.70398
NOTCH2NLB notch 2 N-terminal like B 3.70398
CIMAP1B ciliary microtubule associated protein 1B 3.70398
C20ORF204 chromosome 20 open reading frame 204 3.70398
LY6L lymphocyte antigen 6 family member L 3.70398
CCDC197 coiled-coil domain containing 197 3.70398
ODAPH odontogenesis associated phosphoprotein 3.70398
CHCT1 CHD1 helical C-terminal domain containing 1 3.70398
ELOA2 elongin A2 3.70398
JAML junction adhesion molecule like 3.70398
OR2D2 olfactory receptor, family 2, subfamily D, member 2 3.70398
TIMD4 T-cell immunoglobulin and mucin domain containing 4 3.70398
ALG10B ALG10B, alpha-1,2-glucosyltransferase 3.70398
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 3.70398
PCDHA2 protocadherin alpha 2 3.70398
ATP13A5 ATPase type 13A5 3.70398
LOC390937 Ets2 repressor factor-like 3.70398
CES3 carboxylesterase 3 3.70398
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 3.70398
TPBGL trophoblast glycoprotein-like 3.70398
HRH1 histamine receptor H1 3.70398
RASL10A RAS-like, family 10, member A 3.70398
DMP1 dentin matrix acidic phosphoprotein 1 3.70398
CRLF2 cytokine receptor-like factor 2 3.70398
CCR3 chemokine (C-C motif) receptor 3 3.70398
RASAL3 RAS protein activator like 3 3.70398
ZNF257 zinc finger protein 257 3.70398
OVOL3 ovo-like zinc finger 3 3.70398
CXCL16 chemokine (C-X-C motif) ligand 16 3.70398
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 3.70398
PTP4A1 protein tyrosine phosphatase type IVA, member 1 3.70398
CATSPERD catsper channel auxiliary subunit delta 3.70398
AXDND1 axonemal dynein light chain domain containing 1 3.70398
LCE1C late cornified envelope 1C 3.70398
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 3.70398
ARR3 arrestin 3, retinal (X-arrestin) 3.70398
SLC38A3 solute carrier family 38, member 3 3.70398
RAD51AP2 RAD51 associated protein 2 3.70398
CH25H cholesterol 25-hydroxylase 3.70398
EBF2 early B-cell factor 2 3.70398
NACA2 nascent polypeptide-associated complex alpha subunit 2 3.70398
RPA4 replication protein A4, 30kDa 3.70398
TIGIT T cell immunoreceptor with Ig and ITIM domains 3.70398
HMGB4 high mobility group box 4 3.70398
HS3ST6 heparan sulfate (glucosamine) 3-O-sulfotransferase 6 3.70398
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 3.70398
PLA2G4E phospholipase A2, group IVE 3.70398
GNG8 guanine nucleotide binding protein (G protein), gamma 8 3.70398
PDCD1 programmed cell death 1 3.70398
TBC1D26 TBC1 domain family, member 26 3.70398
LPAR5 lysophosphatidic acid receptor 5 3.70398
ACKR2 atypical chemokine receptor 2 3.70398
SLC38A8 solute carrier family 38, member 8 3.70398
KLHL41 kelch-like family member 41 3.70398
SLCO2B1 solute carrier organic anion transporter family, member 2B1 3.70398
LRRC15 leucine rich repeat containing 15 3.70398
ZCCHC12 zinc finger, CCHC domain containing 12 3.70398
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C 3.70398
COMP cartilage oligomeric matrix protein 3.70398
PCDHGA3 protocadherin gamma subfamily A, 3 3.70398
PRSS33 protease, serine, 33 3.70398
INCA1 inhibitor of CDK, cyclin A1 interacting protein 1 3.70398
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 3.70398
CDH19 cadherin 19, type 2 3.70398
CD5L CD5 molecule-like 3.70398
ARL13A ADP-ribosylation factor-like 13A 3.70398
C11ORF16 chromosome 11 open reading frame 16 3.70398
GOLGA6D golgin A6 family, member D 3.70398
GOLGA6B golgin A6 family, member B 3.70398
NOBOX NOBOX oogenesis homeobox 3.70398
TBC1D10C TBC1 domain family, member 10C 3.70398
TECRL trans-2,3-enoyl-CoA reductase-like 3.70398
SLITRK3 SLIT and NTRK-like family, member 3 3.70398
PPP1R3A protein phosphatase 1, regulatory subunit 3A 3.70398
CD38 CD38 molecule 3.70398
PGPEP1L pyroglutamyl-peptidase I-like 3.70398
BANF2 barrier to autointegration factor 2 3.70398
IL37 interleukin 37 3.70398
PITX3 paired-like homeodomain 3 3.70398
LGALS9 lectin, galactoside-binding, soluble, 9 3.70398
TEX26 testis expressed 26 3.70398
ASCL1 achaete-scute family bHLH transcription factor 1 3.70398
MGP matrix Gla protein 3.70398
NLRP3 NLR family, pyrin domain containing 3 3.70398
CD34 CD34 molecule 3.70398
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 3.70398
PSD2 pleckstrin and Sec7 domain containing 2 3.70398
LST1 leukocyte specific transcript 1 3.70398
SPDEF SAM pointed domain containing ETS transcription factor 3.70398
CLCA1 chloride channel accessory 1 3.70398
DMRTC1 DMRT-like family C1 3.70398
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 3.70398
WFDC13 WAP four-disulfide core domain 13 3.70398
PHACTR3 phosphatase and actin regulator 3 3.70398
NMBR neuromedin B receptor 3.70398
ST18 suppression of tumorigenicity 18, zinc finger 3.70398
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 3.70398
AOC1 amine oxidase, copper containing 1 3.70398
TMEM196 transmembrane protein 196 3.70334
NUDT17 nudix (nucleoside diphosphate linked moiety X)-type motif 17 3.70334
COL8A1 collagen, type VIII, alpha 1 3.70334
STAT5B signal transducer and activator of transcription 5B 3.2156
DDAH2 dimethylarginine dimethylaminohydrolase 2 3.06066
B3GNT9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 3.00249
AKAP14 A kinase (PRKA) anchor protein 14 2.95509
GSKIP GSK3B interacting protein 2.93228
UBAP2L ubiquitin associated protein 2-like 2.89297
IQSEC2 IQ motif and Sec7 domain 2 2.89297
FBXL13 F-box and leucine-rich repeat protein 13 2.72118
DARS1 aspartyl-tRNA synthetase 1 2.70805
BOK BCL2-related ovarian killer 2.69733
CLEC4A C-type lectin domain family 4, member A 2.68047
TEX19 testis expressed 19 2.68047
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB 2.68047
MSX1 msh homeobox 1 2.68047
IL11 interleukin 11 2.68047
RPL39 ribosomal protein L39 2.68047
GOLGA6L10 golgin A6 family-like 10 2.68047
AANAT aralkylamine N-acetyltransferase 2.68047
FRAT1 frequently rearranged in advanced T-cell lymphomas 1 2.68047
KISS1R KISS1 receptor 2.68047
RPL34 ribosomal protein L34 2.64875
E2F2 E2F transcription factor 2 2.63622
WDR4 WD repeat domain 4 2.62905
FRMD8 FERM domain containing 8 2.52944
ZNF689 zinc finger protein 689 2.52944
CHAMP1 chromosome alignment maintaining phosphoprotein 1 2.51743
OGA O-GlcNAcase 2.49902
MOGAT1 monoacylglycerol O-acyltransferase 1 2.47061
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) 2.44599
SCNN1D sodium channel, non voltage gated 1 delta subunit 2.42364
SERINC3 serine incorporator 3 2.3911
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 2.36758
EBLN2 endogenous Bornavirus-like nucleoprotein 2 2.33797
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 2.32831
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type 2.31848
ITGB5 integrin, beta 5 2.31721
SLC25A30 solute carrier family 25, member 30 2.29007
KNTC1 kinetochore associated 1 2.27377
DNA2 DNA replication helicase/nuclease 2 2.27377
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.25319
NBPF8 neuroblastoma breakpoint family, member 8 2.25319
TIGD5 tigger transposable element derived 5 2.22876
LCK LCK proto-oncogene, Src family tyrosine kinase 2.22747
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 2.21792
ZNG1B Zn regulated GTPase metalloprotein activator 1B 2.21792
SPTAN1 spectrin, alpha, non-erythrocytic 1 2.19613
ATP13A2 ATPase type 13A2 2.15985
SDC1 syndecan 1 2.15711
TMEM69 transmembrane protein 69 2.15415
SERP1 stress-associated endoplasmic reticulum protein 1 2.15415
ZNF250 zinc finger protein 250 2.13587
ERI1 exoribonuclease 1 2.11984
MZF1 myeloid zinc finger 1 2.08972
PARS2 prolyl-tRNA synthetase 2, mitochondrial (putative) 2.08167
TRAPPC6B trafficking protein particle complex 6B 2.06375
DENND10 DENN domain containing 10 2.03822
MB21D2 Mab-21 domain containing 2 2.02897
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae) 2.01966
HMGB1 high mobility group box 1 2.00776
KITLG KIT ligand 2.00776
ATG4B autophagy related 4B, cysteine peptidase 2.0043
PIAS2 protein inhibitor of activated STAT, 2 2.00131

decreased expression

Symbol Name Standardized Value
AVP arginine vasopressin -3.70398
JADE1 jade family PHD finger 1 -3.70398
IDO2 indoleamine 2,3-dioxygenase 2 -3.70398
OPN1SW opsin 1 (cone pigments), short-wave-sensitive -3.70398
ECSCR endothelial cell surface expressed chemotaxis and apoptosis regulator -3.70398
TRIM9 tripartite motif containing 9 -3.70398
DOK7 docking protein 7 -3.70334
PRSS51 protease, serine, 51 -3.70334
LHX1 LIM homeobox 1 -3.70334
USP26 ubiquitin specific peptidase 26 -3.70334
CCL25 chemokine (C-C motif) ligand 25 -3.70334
CXORF65 chromosome X open reading frame 65 -3.70334
HCST hematopoietic cell signal transducer -3.70334
MGARP mitochondria-localized glutamic acid-rich protein -3.70334
C1QL3 complement component 1, q subcomponent-like 3 -3.70334
PDE1B phosphodiesterase 1B, calmodulin-dependent -3.70334
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 -3.70334
FXYD2 FXYD domain containing ion transport regulator 2 -3.70334
STKLD1 serine/threonine kinase-like domain containing 1 -3.70334
ITIH6 inter-alpha-trypsin inhibitor heavy chain family, member 6 -3.70334
ETV7 ets variant 7 -3.70334
PCDHGB7 protocadherin gamma subfamily B, 7 -3.70334
ERICH6B glutamate-rich 6B -3.70334
C2CD4B C2 calcium-dependent domain containing 4B -3.70334
CFAP47 cilia and flagella associated protein 47 -3.70334
GBX2 gastrulation brain homeobox 2 -3.70334
KLF4 Kruppel-like factor 4 (gut) -3.70334
PKHD1L1 polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1 -3.70334
NSG2 neuronal vesicle trafficking associated 2 -3.70334
LRRN4 leucine rich repeat neuronal 4 -3.70334
LMO1 LIM domain only 1 (rhombotin 1) -3.70334
CARMIL2 capping protein regulator and myosin 1 linker 2 -3.70334
EDN3 endothelin 3 -3.70334
TTC22 tetratricopeptide repeat domain 22 -3.70334
FNDC9 fibronectin type III domain containing 9 -3.70334
FAM86B1 family with sequence similarity 86, member B1 -3.60431
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa -3.57818
VSIG10L V-set and immunoglobulin domain containing 10 like -3.57106
TOX2 TOX high mobility group box family member 2 -3.47744
UNC5D unc-5 homolog D (C. elegans) -3.45424
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 -3.27015
HUS1 HUS1 checkpoint homolog (S. pombe) -3.15367
YIPF4 Yip1 domain family, member 4 -2.96644
H4C8 H4 clustered histone 8 -2.94335
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) -2.93228
TMEM237 transmembrane protein 237 -2.90307
ANKRD13A ankyrin repeat domain 13A -2.80911
TCEAL2 transcription elongation factor A (SII)-like 2 -2.79529
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 -2.75791
DYNLT2 dynein light chain Tctex-type 2 -2.73583
SMIM15 small integral membrane protein 15 -2.71919
CHAC2 ChaC, cation transport regulator homolog 2 (E. coli) -2.71919
ULK2 unc-51 like autophagy activating kinase 2 -2.65242
ZNF157 zinc finger protein 157 -2.61841
BCL7B B-cell CLL/lymphoma 7B -2.56946
SPDYE12 speedy/RINGO cell cycle regulator family member E12 -2.56658
GAL3ST4 galactose-3-O-sulfotransferase 4 -2.56658
ENO4 enolase family member 4 -2.54636
ZNF470 zinc finger protein 470 -2.51743
TM6SF2 transmembrane 6 superfamily member 2 -2.47904
NAV2 neuron navigator 2 -2.44599
ZNF224 zinc finger protein 224 -2.44599
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) -2.42416
MKI67 marker of proliferation Ki-67 -2.40371
MYCBPAP MYCBP associated protein -2.37122
BCAS3 breast carcinoma amplified sequence 3 -2.35652
ICOSLG inducible T-cell co-stimulator ligand -2.3495
ZNF345 zinc finger protein 345 -2.32612
H4C9 H4 clustered histone 9 -2.32189
CCND3 cyclin D3 -2.31721
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 -2.30596
AKT1 v-akt murine thymoma viral oncogene homolog 1 -2.30452
TRIQK triple QxxK/R motif containing -2.29564
NICN1 nicolin 1 -2.28659
TLCD2 TLC domain containing 2 -2.28659
TMC3 transmembrane channel-like 3 -2.28659
WDR48 WD repeat domain 48 -2.27609
MYH11 myosin, heavy chain 11, smooth muscle -2.26401
SYBU syntabulin (syntaxin-interacting) -2.26401
ZNF225 zinc finger protein 225 -2.26401
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like -2.24293
ROR1 receptor tyrosine kinase-like orphan receptor 1 -2.19921
MAN1A2 mannosidase, alpha, class 1A, member 2 -2.17388
KCTD18 potassium channel tetramerization domain containing 18 -2.16915
POLR2G polymerase (RNA) II (DNA directed) polypeptide G -2.15967
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 -2.15967
ZNF568 zinc finger protein 568 -2.15743
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 -2.15415
HUNK hormonally up-regulated Neu-associated kinase -2.15012
NET1 neuroepithelial cell transforming 1 -2.11278
OXCT1 3-oxoacid CoA transferase 1 -2.10877
ARSB arylsulfatase B -2.10561
GYG1 glycogenin 1 -2.10325
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 -2.06857
MTOR mechanistic target of rapamycin (serine/threonine kinase) -2.06857
POLR3B polymerase (RNA) III (DNA directed) polypeptide B -2.06375
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 -2.05983
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -2.05671
DMKN dermokine -2.05542
CCDC160 coiled-coil domain containing 160 -2.03861
ACE angiotensin I converting enzyme -2.03861
RBM12 RNA binding motif protein 12 -2.03737
PRICKLE1 prickle homolog 1 (Drosophila) -2.03671
LMO4 LIM domain only 4 -2.03501
THEM4 thioesterase superfamily member 4 -2.02601
NDRG3 NDRG family member 3 -2.0043
TFPI2 tissue factor pathway inhibitor 2 -2.0043
SNX15 sorting nexin 15 -2.00116