NUF2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description NUF2, NDC80 kinetochore complex component|This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation. The encoded protein is found to be associated with centromeres of mitotic HeLa cells, which suggests that this protein is a functional homolog of yeast Nuf2. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 83540)
External Link https://ncbi.nlm.nih.gov/gene/83540
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Genes

500 genes differentially expressed following the NUF2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
WDR7 WD repeat domain 7 0.0173426
S100A8 S100 calcium binding protein A8 0.0157039
VEGFA vascular endothelial growth factor A 0.0128191
CA2 carbonic anhydrase II 0.0125033
SCGB2A1 secretoglobin, family 2A, member 1 0.0119155
EMX2 empty spiracles homeobox 2 0.0114246
TNNT1 troponin T type 1 (skeletal, slow) 0.0112238
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.0100604
TMSB15A thymosin beta 15a 0.00986392
CSTA cystatin A (stefin A) 0.0087472
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.00840211
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.00816788
S100A9 S100 calcium binding protein A9 0.00802177
RGCC regulator of cell cycle 0.00793046
GJA1 gap junction protein, alpha 1, 43kDa 0.0079093
KRT14 keratin 14, type I 0.00775405
SCGB1D2 secretoglobin, family 1D, member 2 0.00762888
FABP4 fatty acid binding protein 4, adipocyte 0.00760835
TSPAN12 tetraspanin 12 0.00757627
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.00754905
DIPK1A divergent protein kinase domain 1A 0.00754853
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.00754532
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.00748691
PEG3 paternally expressed 3 0.00745414
IGFBP5 insulin-like growth factor binding protein 5 0.00744548
CRYAB crystallin, alpha B 0.00744243
KRT23 keratin 23, type I 0.00727352
NRCAM neuronal cell adhesion molecule 0.00726196
MFAP5 microfibrillar associated protein 5 0.00725802
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 0.00707489
GADD45A growth arrest and DNA-damage-inducible, alpha 0.0070318
POSTN periostin, osteoblast specific factor 0.00700963
ESM1 endothelial cell-specific molecule 1 0.00694619
SCGB2A2 secretoglobin, family 2A, member 2 0.00693715
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00679993
MOSPD1 motile sperm domain containing 1 0.00674028
CLCA4 chloride channel accessory 4 0.00673502
TCTA T-cell leukemia translocation altered 0.00671546
CRABP2 cellular retinoic acid binding protein 2 0.00670825
HTRA1 HtrA serine peptidase 1 0.00666891
RGS4 regulator of G-protein signaling 4 0.00658101
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00656847
TIMP3 TIMP metallopeptidase inhibitor 3 0.00654187
ASS1 argininosuccinate synthase 1 0.00653431
CA12 carbonic anhydrase XII 0.00643008
PAN2 PAN2 poly(A) specific ribonuclease subunit 0.00642857
CTNND1 catenin (cadherin-associated protein), delta 1 0.00641266
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00640695
CDC20 cell division cycle 20 0.00637059
PRTN3 proteinase 3 0.00635756
ZFPM2 zinc finger protein, FOG family member 2 0.0063232
MT1X metallothionein 1X 0.00627192
MT1G metallothionein 1G 0.00624773
PODXL podocalyxin-like 0.00622669
TXNL1 thioredoxin-like 1 0.00616468
ZNF395 zinc finger protein 395 0.00615119
SLC38A1 solute carrier family 38, member 1 0.00614912
YPEL5 yippee-like 5 (Drosophila) 0.006146
MPPED2 metallophosphoesterase domain containing 2 0.00614229
CA4 carbonic anhydrase IV 0.00609969
RAP1GAP2 RAP1 GTPase activating protein 2 0.00608199
S100A14 S100 calcium binding protein A14 0.00607193
SHB Src homology 2 domain containing adaptor protein B 0.0060655
CD200 CD200 molecule 0.00606453
HCRT hypocretin (orexin) neuropeptide precursor 0.00604065
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.00602227
ARMCX1 armadillo repeat containing, X-linked 1 0.00601048
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.00600997
SCRG1 stimulator of chondrogenesis 1 0.00595603
CSRP2 cysteine and glycine-rich protein 2 0.00589735
MT1F metallothionein 1F 0.00586589
ZNF415 zinc finger protein 415 0.00585818
DOK5 docking protein 5 0.00585213
TRHDE thyrotropin-releasing hormone degrading enzyme 0.00583629
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00577691
PTPRO protein tyrosine phosphatase, receptor type, O 0.00576757
NARS1 asparaginyl-tRNA synthetase 1 0.00569087
FHL1 four and a half LIM domains 1 0.00568797
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.00568086
MBD2 methyl-CpG binding domain protein 2 0.00566842
JAM2 junctional adhesion molecule 2 0.0056511
ESR1 estrogen receptor 1 0.00563646
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 0.00563462
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 0.00563319
IFNAR1 interferon (alpha, beta and omega) receptor 1 0.00563178
CDK14 cyclin-dependent kinase 14 0.00559045
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 0.00558088
HDAC9 histone deacetylase 9 0.00555129
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.00554625
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.00553726
PDE2A phosphodiesterase 2A, cGMP-stimulated 0.00553616
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.00552996
LDB2 LIM domain binding 2 0.00550765
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) 0.00550228
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.0054698
TAGLN transgelin 0.00546645
SCN3A sodium channel, voltage gated, type III alpha subunit 0.00546631
BLNK B-cell linker 0.00545083
MXI1 MAX interactor 1, dimerization protein 0.00542319
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 0.00541572
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.00532338
RIDA reactive intermediate imine deaminase A homolog 0.00527665
ORC1 origin recognition complex, subunit 1 0.00527302
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.00526727
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.00526244
ANGPT2 angiopoietin 2 0.00523579
TLN1 talin 1 0.00520217
CD36 CD36 molecule (thrombospondin receptor) 0.00516456
FCGBP Fc fragment of IgG binding protein 0.00511551
ADGRL4 adhesion G protein-coupled receptor L4 0.00509038
OSBPL10 oxysterol binding protein-like 10 0.00507656
POLI polymerase (DNA directed) iota 0.00507139
GSTA1 glutathione S-transferase alpha 1 0.00506312
GUK1 guanylate kinase 1 0.00506305
BEX4 brain expressed, X-linked 4 0.00501384
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 0.00500248
EXT1 exostosin glycosyltransferase 1 0.00498036
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 0.0049664
GNAS GNAS complex locus 0.00496591
INHBE inhibin, beta E 0.00496015
RGS16 regulator of G-protein signaling 16 0.00495817
BSG basigin (Ok blood group) 0.00495348
FOXG1 forkhead box G1 0.00494621
DIO1 deiodinase, iodothyronine, type I 0.00493557
NUPR1 nuclear protein, transcriptional regulator, 1 0.00491874
BCHE butyrylcholinesterase 0.00490276
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 0.00488607
ACTA1 actin, alpha 1, skeletal muscle 0.00488051
CD52 CD52 molecule 0.00487362
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 0.00484859
LPPR4 lipid phosphate phosphatase-related protein type 4 0.00482567
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.00482541
LINC00623 long intergenic non-protein coding RNA 623 0.00482331
CSAD cysteine sulfinic acid decarboxylase 0.0048155
ARF3 ADP-ribosylation factor 3 0.00480547
THEMIS2 thymocyte selection associated family member 2 0.00479964
CD9 CD9 molecule 0.00479807
ZNF271P zinc finger protein 271, pseudogene 0.00477579
FAM114A1 family with sequence similarity 114, member A1 0.00477532
CLDN7 claudin 7 0.00476544
PROM1 prominin 1 0.00470601
PCOLCE2 procollagen C-endopeptidase enhancer 2 0.00468352
NBEA neurobeachin 0.00467579
NUAK1 NUAK family, SNF1-like kinase, 1 0.0046693
AOX1 aldehyde oxidase 1 0.00466701
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 0.00466696
EHD3 EH-domain containing 3 0.00466164
TNIP1 TNFAIP3 interacting protein 1 0.00465523
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.00465396
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 0.00464467
RIPOR2 RHO family interacting cell polarization regulator 2 0.00464111
FLT1 fms-related tyrosine kinase 1 0.00462419
LDOC1 leucine zipper, down-regulated in cancer 1 0.00461644
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.00459689
CDH13 cadherin 13 0.00458785
H1-2 H1.2 linker histone, cluster member 0.00457321
PITX1 paired-like homeodomain 1 0.00456657
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) 0.00456264
ENPEP glutamyl aminopeptidase (aminopeptidase A) 0.00455372
ABLIM1 actin binding LIM protein 1 0.00454587
ACKR3 atypical chemokine receptor 3 0.00453852
LIAS lipoic acid synthetase 0.00453517
ELMO1 engulfment and cell motility 1 0.00449827
SH3YL1 SH3 and SYLF domain containing 1 0.00449403
LRRC2 leucine rich repeat containing 2 0.00447331
BPGM 2,3-bisphosphoglycerate mutase 0.0044115
PKP2 plakophilin 2 0.00440969
NLGN1 neuroligin 1 0.00440686
MT1H metallothionein 1H 0.00440171
SLN sarcolipin 0.00440156
MEF2C myocyte enhancer factor 2C 0.00439667
FAM117A family with sequence similarity 117, member A 0.00437936
FAM169A family with sequence similarity 169, member A 0.00437655
ZNF91 zinc finger protein 91 0.00437389
RND3 Rho family GTPase 3 0.00435076
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.00434308
FTH1 ferritin, heavy polypeptide 1 0.00434282
FGG fibrinogen gamma chain 0.00434092
MRPS10 mitochondrial ribosomal protein S10 0.00433932
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 0.00433878
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 0.00432171
EN1 engrailed homeobox 1 0.0043185
FGF9 fibroblast growth factor 9 0.00431646
BAALC brain and acute leukemia, cytoplasmic 0.00431304
SCPEP1 serine carboxypeptidase 1 0.00430333
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.00430332
IL1B interleukin 1, beta 0.00429782
HIST1H2AC histone cluster 1, H2ac 0.00428962
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.00428919
NPTX2 neuronal pentraxin II 0.0042811
GYPA glycophorin A (MNS blood group) 0.00427045
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.00426787
ADGRL2 adhesion G protein-coupled receptor L2 0.00426463
AP2S1 adaptor-related protein complex 2, sigma 1 subunit 0.00424795
FLOT1 flotillin 1 0.00424109
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 0.00422083
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 0.00421204
KRT5 keratin 5, type II 0.004209
ADCY2 adenylate cyclase 2 (brain) 0.00419428
CRIP1 cysteine-rich protein 1 (intestinal) 0.00419297
DIRAS2 DIRAS family, GTP-binding RAS-like 2 0.00419064
TRIB2 tribbles pseudokinase 2 0.0041864
MECOM MDS1 and EVI1 complex locus 0.00417292
LRRC17 leucine rich repeat containing 17 0.00416716
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 0.00416504
GRIA3 glutamate receptor, ionotropic, AMPA 3 0.00416455
ARG2 arginase 2 0.00416413
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00415763
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 0.00415537
ACTG2 actin, gamma 2, smooth muscle, enteric 0.00414614
MT3 metallothionein 3 0.00414398
PDE8B phosphodiesterase 8B 0.00413926
PTK2B protein tyrosine kinase 2 beta 0.00412421
C14ORF132 chromosome 14 open reading frame 132 0.00410607
JCAD junctional cadherin 5 associated 0.00409428
GREM1 gremlin 1, DAN family BMP antagonist 0.00408763
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.00408649
NOX4 NADPH oxidase 4 0.00408642
SPATA7 spermatogenesis associated 7 0.00407933
STC2 stanniocalcin 2 0.0040731
MUC2 mucin 2, oligomeric mucus/gel-forming 0.00406831
KRT13 keratin 13, type I 0.00406322
PGAM1 phosphoglycerate mutase 1 (brain) 0.0040484
KLRF1 killer cell lectin-like receptor subfamily F, member 1 0.00404762
SYNE3 spectrin repeat containing, nuclear envelope family member 3 0.00404354
LY6H lymphocyte antigen 6 complex, locus H 0.00403595
ITGA1 integrin, alpha 1 0.00403414
CNN3 calponin 3, acidic 0.00401954
ELANE elastase, neutrophil expressed 0.00401757
NCALD neurocalcin delta 0.0040063
MAGOH mago-nashi homolog, proliferation-associated (Drosophila) 0.00400123
TOX thymocyte selection-associated high mobility group box 0.00400015
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 0.00399521
AK5 adenylate kinase 5 0.00398745
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 0.00398541
MB myoglobin 0.00398109
MT1E metallothionein 1E 0.00398054
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.00397389
ZNF331 zinc finger protein 331 0.0039669
HYAL1 hyaluronoglucosaminidase 1 0.00396526
SDC1 syndecan 1 0.00396105
CCK cholecystokinin 0.00396102
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 0.00395739
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.00394936
FXYD6 FXYD domain containing ion transport regulator 6 0.00394661
KLK5 kallikrein-related peptidase 5 0.00394323
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.00394274
RPRD1A regulation of nuclear pre-mRNA domain containing 1A 0.00393541
KLHL4 kelch-like family member 4 0.00392809
ZNF573 zinc finger protein 573 0.00392116

decreased expression

Symbol Name Standardized Value
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.0113562
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.010816
AGR2 anterior gradient 2 -0.0101619
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00951851
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.00936029
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00860579
IFI44L interferon-induced protein 44-like -0.00843641
SMC1A structural maintenance of chromosomes 1A -0.00834513
TSPAN8 tetraspanin 8 -0.00825156
NTS neurotensin -0.00799465
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00783345
TNC tenascin C -0.0076646
C1R complement component 1, r subcomponent -0.00763594
C1S complement component 1, s subcomponent -0.00747128
SYNGR3 synaptogyrin 3 -0.00733784
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00730862
MET MET proto-oncogene, receptor tyrosine kinase -0.00729193
CDCA4 cell division cycle associated 4 -0.00719528
GPX2 glutathione peroxidase 2 -0.0071617
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D -0.00713524
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.00683057
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 -0.00680359
ADCY3 adenylate cyclase 3 -0.00678771
HOXC6 homeobox C6 -0.00675722
NBL1 neuroblastoma 1, DAN family BMP antagonist -0.00674194
PROS1 protein S (alpha) -0.0067156
ISG15 ISG15 ubiquitin-like modifier -0.00668737
IFI27 interferon, alpha-inducible protein 27 -0.00667824
LAPTM4B lysosomal protein transmembrane 4 beta -0.00663181
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0066275
ZBTB18 zinc finger and BTB domain containing 18 -0.00661011
AKR1C2 aldo-keto reductase family 1, member C2 -0.00657821
AKR1C1 aldo-keto reductase family 1, member C1 -0.00657387
TGM2 transglutaminase 2 -0.00656049
BIRC3 baculoviral IAP repeat containing 3 -0.00655636
IL2RG interleukin 2 receptor, gamma -0.00655226
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -0.00652991
COCH cochlin -0.00647382
CFB complement factor B -0.00641347
STOM stomatin -0.006407
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.00638974
PTCH1 patched 1 -0.00633279
TSPAN4 tetraspanin 4 -0.00621178
ERAP2 endoplasmic reticulum aminopeptidase 2 -0.00619367
SFTPA2 surfactant protein A2 -0.00618497
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa -0.00617755
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 -0.00616411
IFI6 interferon, alpha-inducible protein 6 -0.0061142
JPT2 Jupiter microtubule associated homolog 2 -0.0060976
IFITM1 interferon induced transmembrane protein 1 -0.00609672
MAGED1 melanoma antigen family D1 -0.00594672
MX1 MX dynamin-like GTPase 1 -0.00594659
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.00594532
TATDN2 TatD DNase domain containing 2 -0.00589707
BST2 bone marrow stromal cell antigen 2 -0.00588607
CD82 CD82 molecule -0.00587954
PTGES prostaglandin E synthase -0.00578695
SFTPC surfactant protein C -0.00577026
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00575924
RNF167 ring finger protein 167 -0.00575741
IL6ST interleukin 6 signal transducer -0.00575541
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase -0.00574841
TESC tescalcin -0.00571066
LAMC1 laminin, gamma 1 (formerly LAMB2) -0.00569356
FOXC1 forkhead box C1 -0.00568528
OASL 2'-5'-oligoadenylate synthetase-like -0.00567243
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.00563432
FAM171A1 family with sequence similarity 171, member A1 -0.00562527
ATP10B ATPase, class V, type 10B -0.005611
TM9SF3 transmembrane 9 superfamily member 3 -0.0055104
CPS1 carbamoyl-phosphate synthase 1, mitochondrial -0.00550769
CH25H cholesterol 25-hydroxylase -0.00546699
PDE4D phosphodiesterase 4D, cAMP-specific -0.00545452
NOTCH2 notch 2 -0.00543085
TXNIP thioredoxin interacting protein -0.00540846
FBLN1 fibulin 1 -0.00536381
ADNP activity-dependent neuroprotector homeobox -0.00534738
BMI1 BMI1 proto-oncogene, polycomb ring finger -0.00533724
SORD sorbitol dehydrogenase -0.00532916
SLAMF7 SLAM family member 7 -0.00530004
ITM2A integral membrane protein 2A -0.00527552
KIAA0125 KIAA0125 -0.00523162
PPARG peroxisome proliferator-activated receptor gamma -0.00520331
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 -0.00514835
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.00514301
MMP7 matrix metallopeptidase 7 -0.00513843
MFAP4 microfibrillar-associated protein 4 -0.00512463
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase -0.00510898
TMC5 transmembrane channel-like 5 -0.0050869
CAPRIN1 cell cycle associated protein 1 -0.00506812
FAM3C family with sequence similarity 3, member C -0.00505067
SGMS1 sphingomyelin synthase 1 -0.0050351
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.00502289
CLDN1 claudin 1 -0.00501496
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 -0.00501016
DMBT1 deleted in malignant brain tumors 1 -0.00500688
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00500417
SFTPB surfactant protein B -0.00499402
SMOX spermine oxidase -0.0049831
SPRR2B small proline-rich protein 2B -0.00497856
NBR1 neighbor of BRCA1 gene 1 -0.00497838
SSBP2 single-stranded DNA binding protein 2 -0.00497229
FBN1 fibrillin 1 -0.00496411
CPD carboxypeptidase D -0.00496071
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 -0.00495994
MCOLN1 mucolipin 1 -0.00494862
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -0.00491602
XAF1 XIAP associated factor 1 -0.00491332
C4BPA complement component 4 binding protein, alpha -0.00490454
TM4SF1 transmembrane 4 L six family member 1 -0.0048855
RAB20 RAB20, member RAS oncogene family -0.00487905
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.00482897
RSAD2 radical S-adenosyl methionine domain containing 2 -0.00482626
EPHB2 EPH receptor B2 -0.00480467
BCLAF1 BCL2-associated transcription factor 1 -0.00478315
GPR171 G protein-coupled receptor 171 -0.00477726
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.00476667
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -0.00475426
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -0.00474568
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 -0.00473184
WNT5A wingless-type MMTV integration site family, member 5A -0.00472156
RAD23B RAD23 homolog B (S. cerevisiae) -0.00471152
IL7R interleukin 7 receptor -0.00470017
IL2RB interleukin 2 receptor, beta -0.0046969
FUS FUS RNA binding protein -0.00469305
DLX2 distal-less homeobox 2 -0.00469016
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) -0.00467912
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.00467294
POF1B premature ovarian failure, 1B -0.00466968
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.00466729
ADGRG6 adhesion G protein-coupled receptor G6 -0.00466355
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 -0.00465218
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin -0.00464842
RPN2 ribophorin II -0.00463322
CHEK2 checkpoint kinase 2 -0.00461411
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.00461069
NCKAP1L NCK-associated protein 1-like -0.00457229
TJP2 tight junction protein 2 -0.00456047
PDZD8 PDZ domain containing 8 -0.00455304
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) -0.00454187
IFITM2 interferon induced transmembrane protein 2 -0.00451914
LAMP2 lysosomal-associated membrane protein 2 -0.00451798
ACACA acetyl-CoA carboxylase alpha -0.00451276
TAC1 tachykinin, precursor 1 -0.00451079
CTR9 CTR9, Paf1/RNA polymerase II complex component -0.0045007
PRRX2 paired related homeobox 2 -0.00449622
IL13RA2 interleukin 13 receptor, alpha 2 -0.00449469
NAMPT nicotinamide phosphoribosyltransferase -0.00449413
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.00449402
PGC progastricsin (pepsinogen C) -0.00446937
FUCA1 fucosidase, alpha-L- 1, tissue -0.00446092
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -0.00445831
XIC X chromosome inactivation center -0.00444335
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) -0.00444024
HNRNPR heterogeneous nuclear ribonucleoprotein R -0.00443409
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) -0.00443233
RNF43 ring finger protein 43 -0.00442795
SPTAN1 spectrin, alpha, non-erythrocytic 1 -0.00442611
MALL mal, T-cell differentiation protein-like -0.0044252
CHPT1 choline phosphotransferase 1 -0.00441964
FAM111A family with sequence similarity 111, member A -0.00439989
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -0.00439643
CCL15 chemokine (C-C motif) ligand 15 -0.00438398
PRF1 perforin 1 (pore forming protein) -0.00436296
IDE insulin-degrading enzyme -0.00435663
PLAT plasminogen activator, tissue -0.00435264
CD151 CD151 molecule (Raph blood group) -0.00434947
CTSW cathepsin W -0.00434693
SLAMF1 signaling lymphocytic activation molecule family member 1 -0.00434532
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 -0.0043341
NCAPD3 non-SMC condensin II complex, subunit D3 -0.00433061
FGFR3 fibroblast growth factor receptor 3 -0.0043216
TSPYL1 TSPY-like 1 -0.00431681
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 -0.00430138
NPAT nuclear protein, ataxia-telangiectasia locus -0.00430088
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00429909
SCARA3 scavenger receptor class A, member 3 -0.00427652
NEFH neurofilament, heavy polypeptide -0.00426783
PLA1A phospholipase A1 member A -0.00426558
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 -0.00426394
MYO1C myosin IC -0.00425364
PSIP1 PC4 and SFRS1 interacting protein 1 -0.00425079
GJB1 gap junction protein, beta 1, 32kDa -0.00424755
RETREG3 reticulophagy regulator family member 3 -0.00423827
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.00423265
STEAP1 six transmembrane epithelial antigen of the prostate 1 -0.00423079
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -0.00422758
COL4A5 collagen, type IV, alpha 5 -0.00421277
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 -0.00420703
NPY neuropeptide Y -0.00420373
AFF1 AF4/FMR2 family, member 1 -0.00419736
RGS1 regulator of G-protein signaling 1 -0.00419553
ECPAS Ecm29 proteasome adaptor and scaffold -0.00418073
LAMC2 laminin, gamma 2 -0.00417356
CRTC3 CREB regulated transcription coactivator 3 -0.00416769
S100P S100 calcium binding protein P -0.0041606
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -0.00415771
VCX2 variable charge, X-linked 2 -0.00415764
PKP3 plakophilin 3 -0.00414826
NID2 nidogen 2 (osteonidogen) -0.00413801
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.00412197
MUC13 mucin 13, cell surface associated -0.00412155
NKX2-1 NK2 homeobox 1 -0.00411287
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.0041117
BATF3 basic leucine zipper transcription factor, ATF-like 3 -0.00411157
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) -0.00410597
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) -0.0041055
NFE2L3 nuclear factor, erythroid 2-like 3 -0.00410235
APOL6 apolipoprotein L, 6 -0.00410081
RBM3 RNA binding motif (RNP1, RRM) protein 3 -0.00408466
RCAN1 regulator of calcineurin 1 -0.00407029
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -0.00406836
JCHAIN joining chain of multimeric IgA and IgM -0.00406546
SPAG1 sperm associated antigen 1 -0.00405836
MMP1 matrix metallopeptidase 1 -0.00405457
CXCL5 chemokine (C-X-C motif) ligand 5 -0.00405423
BCL7B B-cell CLL/lymphoma 7B -0.00405286
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like -0.00404689
PDHX pyruvate dehydrogenase complex, component X -0.00404369
WEE1 WEE1 G2 checkpoint kinase -0.00403858
SIRT3 sirtuin 3 -0.00401999
DEFB4A defensin, beta 4A -0.0040153
SLC19A1 solute carrier family 19 (folate transporter), member 1 -0.00400942
CST3 cystatin C -0.00400928
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) -0.00400107
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) -0.00398705
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa -0.00398575
SOD3 superoxide dismutase 3, extracellular -0.00397894
PRNP prion protein -0.00397844
TPD52 tumor protein D52 -0.00397296
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 -0.00397143
GRSF1 G-rich RNA sequence binding factor 1 -0.00397093
NAAA N-acylethanolamine acid amidase -0.00396575
BIN1 bridging integrator 1 -0.00396131
CAVIN2 caveolae associated protein 2 -0.00395726
UTRN utrophin -0.00395247
TG thyroglobulin -0.00394993
PDIA3 protein disulfide isomerase family A, member 3 -0.0039474
APOD apolipoprotein D -0.00394097
LCN2 lipocalin 2 -0.00393927
DVL1 dishevelled segment polarity protein 1 -0.00392583
TKTL1 transketolase-like 1 -0.00391262
CST7 cystatin F (leukocystatin) -0.00390173
APOL1 apolipoprotein L, 1 -0.00389166
CFLAR CASP8 and FADD-like apoptosis regulator -0.00388313
FMO2 flavin containing monooxygenase 2 (non-functional) -0.00388189
FOXF2 forkhead box F2 -0.0038767
GP1BA glycoprotein Ib (platelet), alpha polypeptide -0.00387232
SSX1 synovial sarcoma, X breakpoint 1 -0.00386953
GIMAP5 GTPase, IMAP family member 5 -0.00386687