NUP155 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description nucleoporin 155kDa|Nucleoporins are proteins that play an important role in the assembly and functioning of the nuclear pore complex (NPC) which regulates the movement of macromolecules across the nuclear envelope (NE). The protein encoded by this gene plays a role in the fusion of NE vesicles and formation of the double membrane NE. The protein may also be involved in cardiac physiology and may be associated with the pathogenesis of atrial fibrillation. Alternative splicing results in multiple transcript variants of this gene. A pseudogene associated with this gene is located on chromosome 6. [provided by RefSeq, May 2013] (NCBI Entrez Gene Database, 9631)
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Genes

315 genes differentially expressed following the NUP155 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
MUC1 mucin 1, cell surface associated 2.7521
POC5 POC5 centriolar protein 2.7521
ALPK2 alpha-kinase 2 2.7521
CEPT1 choline/ethanolamine phosphotransferase 1 2.7521
SP7 Sp7 transcription factor 2.7521
TCAF2 TRPM8 channel-associated factor 2 2.7521
UNC45B unc-45 homolog B (C. elegans) 2.7521
BIRC3 baculoviral IAP repeat containing 3 2.7521
CA9 carbonic anhydrase IX 2.7521
ADAMTSL5 ADAMTS-like 5 2.7521
MFAP4 microfibrillar-associated protein 4 2.7521
DMRTC1B DMRT-like family C1B 2.7521
SLC16A6 solute carrier family 16, member 6 2.7521
CD160 CD160 molecule 2.7521
RAX retina and anterior neural fold homeobox 2.7521
PCDHB6 protocadherin beta 6 2.7521
HES3 hes family bHLH transcription factor 3 2.7521
SERPINE3 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3 2.7521
HORMAD2 HORMA domain containing 2 2.7521
IL5RA interleukin 5 receptor, alpha 2.7521
GJB5 gap junction protein, beta 5, 31.1kDa 2.7521
GJB3 gap junction protein, beta 3, 31kDa 2.7521
GNAT3 guanine nucleotide binding protein, alpha transducing 3 2.7521
TDRD6 tudor domain containing 6 2.7521
NR4A3 nuclear receptor subfamily 4, group A, member 3 2.7521
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 2.7521
NPR3 natriuretic peptide receptor 3 2.7521
RHOJ ras homolog family member J 2.7521
WFDC13 WAP four-disulfide core domain 13 2.7521
SPINT4 serine peptidase inhibitor, Kunitz type 4 2.7521
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 2.7521
ASCL1 achaete-scute family bHLH transcription factor 1 2.7521
NLRP5 NLR family, pyrin domain containing 5 2.7521
ATG4A autophagy related 4A, cysteine peptidase 2.7521
CPLX1 complexin 1 2.7521
RASSF6 Ras association (RalGDS/AF-6) domain family member 6 2.7521
OR1L8 olfactory receptor, family 1, subfamily L, member 8 2.7521
SHISA7 shisa family member 7 2.7521
UBA7 ubiquitin-like modifier activating enzyme 7 2.7521
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 2.7521
RLN1 relaxin 1 2.7521
PNOC prepronociceptin 2.7521
CRYGB crystallin, gamma B 2.7521
OXT oxytocin/neurophysin I prepropeptide 2.7521
ACOT12 acyl-CoA thioesterase 12 2.7521
ZNF648 zinc finger protein 648 2.7521
TXNDC8 thioredoxin domain containing 8 (spermatozoa) 2.7521
OR1R1 olfactory receptor family 1 subfamily R member 1 2.7521
OR52E5 olfactory receptor, family 52, subfamily E, member 5 2.7521
HTR3C 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic 2.7521
MROH5 maestro heat-like repeat family member 5 2.7521
DLK2 delta-like 2 homolog (Drosophila) 2.7521
FOXD4L5 forkhead box D4-like 5 2.7521
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 2.7521
GPR132 G protein-coupled receptor 132 2.7521
COXFA4L2 cytochrome c oxidase hypoxia associated subunit FA4L2 2.7521
GTSF1 gametocyte specific factor 1 2.7521
PNLIPRP2 pancreatic lipase-related protein 2 2.7521
GIPC3 GIPC PDZ domain containing family, member 3 2.7521
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 2.7521
DRC5 dynein regulatory complex subunit 5 2.7521
MAP3K4-AS1 MAP3K4 antisense RNA 1 2.7521
DEFB109B defensin beta 109B 2.7521
H3C4 H3 clustered histone 4 2.7521
MAJIN membrane anchored junction protein 2.7521
ELOA2 elongin A2 2.7521
CFAP141 cilia and flagella associated protein 141 2.7521
TAFA3 TAFA chemokine like family member 3 2.7521
VEGFD vascular endothelial growth factor D 2.7521
GZMM granzyme M (lymphocyte met-ase 1) 2.7521
TLR7 toll-like receptor 7 2.7521
SLC6A19 solute carrier family 6 (neutral amino acid transporter), member 19 2.7521
CD274 CD274 molecule 2.7521
CD2 CD2 molecule 2.7521
GOT1L1 glutamic-oxaloacetic transaminase 1-like 1 2.7521
LAX1 lymphocyte transmembrane adaptor 1 2.7521
USP28 ubiquitin specific peptidase 28 2.7521
SCG2 secretogranin II 2.7521
ADGRE3 adhesion G protein-coupled receptor E3 2.7521
NPPC natriuretic peptide C 2.7521
TMPRSS11A transmembrane protease, serine 11A 2.7521
SIX6 SIX homeobox 6 2.7521
GJA3 gap junction protein, alpha 3, 46kDa 2.7521
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 2.7521
TEX101 testis expressed 101 2.7521
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 2.7521
PCDHA3 protocadherin alpha 3 2.7521
IL12RB1 interleukin 12 receptor, beta 1 2.7521
ISM2 isthmin 2 2.7521
FAM153A family with sequence similarity 153, member A 2.7521
USH1G Usher syndrome 1G (autosomal recessive) 2.7521
FOXL1 forkhead box L1 2.7521
CX3CL1 chemokine (C-X3-C motif) ligand 1 2.7521
COL9A2 collagen, type IX, alpha 2 2.7521
LRRC25 leucine rich repeat containing 25 2.7521
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 2.7521
DYDC1 DPY30 domain containing 1 2.7521
GP2 glycoprotein 2 (zymogen granule membrane) 2.7521
POF1B premature ovarian failure, 1B 2.7521
CSF1R colony stimulating factor 1 receptor 2.7521
MAMDC4 MAM domain containing 4 2.7521
PABPC4L poly(A) binding protein, cytoplasmic 4-like 2.7521
NXF2B nuclear RNA export factor 2B 2.7521
SOWAHA sosondowah ankyrin repeat domain family member A 2.7521
PCDHGB1 protocadherin gamma subfamily B, 1 2.7521
PCDHGB2 protocadherin gamma subfamily B, 2 2.7521
NPPA natriuretic peptide A 2.7521
LRRC43 leucine rich repeat containing 43 2.7521
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.7521
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 2.7521
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 2.7521
DNAJB13 DnaJ (Hsp40) homolog, subfamily B, member 13 2.7521
KLF1 Kruppel-like factor 1 (erythroid) 2.7521
FAM177B family with sequence similarity 177, member B 2.7521
DAW1 dynein assembly factor with WDR repeat domains 1 2.7521
RAB40AL RAB40A, member RAS oncogene family-like 2.7521
NT5C1B 5'-nucleotidase, cytosolic IB 2.7521
CATIP ciliogenesis associated TTC17 interacting protein 2.7521
EGR2 early growth response 2 2.7521
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal) 2.7521
SMIM17 small integral membrane protein 17 2.7521
VSTM1 V-set and transmembrane domain containing 1 2.7521
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D 2.7521
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C 2.7521
NIPAL4 NIPA-like domain containing 4 2.7521
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 2.7521
HUS1B HUS1 checkpoint homolog b (S. pombe) 2.7521
PCDHGA2 protocadherin gamma subfamily A, 2 2.7521
VWA3B von Willebrand factor A domain containing 3B 2.7521
LHX2 LIM homeobox 2 2.7521
IL1A interleukin 1, alpha 2.7521
PCDH12 protocadherin 12 2.7521
FOXP2 forkhead box P2 2.7521
ECE2 endothelin converting enzyme 2 2.7521
LRRC32 leucine rich repeat containing 32 2.7521
NUTM2F NUT family member 2F 2.7521
EPX eosinophil peroxidase 2.7521
AMER2 APC membrane recruitment protein 2 2.7521
XCR1 chemokine (C motif) receptor 1 2.7521
TGM6 transglutaminase 6 2.7521
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4 2.7521
RERGL RERG/RAS-like 2.7521
INCA1 inhibitor of CDK, cyclin A1 interacting protein 1 2.7521
GOLGA8N golgin A8 family, member N 2.7521
TMEM86B transmembrane protein 86B 2.7521
ROM1 retinal outer segment membrane protein 1 2.7521
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 2.7521
GOLGA8R golgin A8 family, member R 2.7521
DQX1 DEAQ box RNA-dependent ATPase 1 2.7521
GSDMA gasdermin A 2.7521
TEX35 testis expressed 35 2.7521
CCDC166 coiled-coil domain containing 166 2.7521
CPO carboxypeptidase O 2.7521
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2 2.7521
NKPD1 NTPase, KAP family P-loop domain containing 1 2.7521
GNG8 guanine nucleotide binding protein (G protein), gamma 8 2.7521
DEFB118 defensin, beta 118 2.7521
PMEPA1 prostate transmembrane protein, androgen induced 1 2.7521
ACSM1 acyl-CoA synthetase medium-chain family member 1 2.7521
SLC17A3 solute carrier family 17 (organic anion transporter), member 3 2.7521
ANKRD33 ankyrin repeat domain 33 2.7521
LY6G5C lymphocyte antigen 6 complex, locus G5C 2.7521
CARD9 caspase recruitment domain family, member 9 2.7521
PGM5 phosphoglucomutase 5 2.7521
WFDC10A WAP four-disulfide core domain 10A 2.7521
TEC tec protein tyrosine kinase 2.68625
GAMT guanidinoacetate N-methyltransferase 2.60877
SCN7A sodium channel, voltage gated, type VII alpha subunit 2.44689
HSPA4L heat shock 70kDa protein 4-like 2.43649
PIGL phosphatidylinositol glycan anchor biosynthesis, class L 2.41811
RAMACL RNA guanine-7 methyltransferase activating subunit like 2.41609
SPIN2B spindlin family, member 2B 2.39637
CCNJL cyclin J-like 2.39637
DENND4A DENN/MADD domain containing 4A 2.39075
LTBP2 latent transforming growth factor beta binding protein 2 2.38824
LAMP5 lysosomal-associated membrane protein family, member 5 2.38824
TASOR2 transcription activation suppressor family member 2 2.3471
TOR2A torsin family 2, member A 2.3471
KLHL29 kelch-like family member 29 2.3471
TANK TRAF family member-associated NFKB activator 2.32313
DUS4L dihydrouridine synthase 4-like (S. cerevisiae) 2.31992
PIWIL1 piwi-like RNA-mediated gene silencing 1 2.31241
RSPH14 radial spoke head 14 homolog (Chlamydomonas) 2.31241
C1ORF87 chromosome 1 open reading frame 87 2.31241
RTCA RNA 3'-terminal phosphate cyclase 2.27686
WDSUB1 WD repeat, sterile alpha motif and U-box domain containing 1 2.26783
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 2.25137
TMCC1 transmembrane and coiled-coil domain family 1 2.23318
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) 2.23005
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 2.22519
POLR2H polymerase (RNA) II (DNA directed) polypeptide H 2.22519
LYRM7 LYR motif containing 7 2.2221
AP3M1 adaptor-related protein complex 3, mu 1 subunit 2.21464
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 2.21464
ZXDC ZXD family zinc finger C 2.21322
MVK mevalonate kinase 2.19841
PIF1 PIF1 5'-to-3' DNA helicase 2.18974
CD320 CD320 molecule 2.1855
SYCE1L synaptonemal complex central element protein 1-like 2.15506
STRN4 striatin, calmodulin binding protein 4 2.15506
GHDC GH3 domain containing 2.13113
MND1 meiotic nuclear divisions 1 homolog (S. cerevisiae) 2.13104
MIGA2 mitoguardin 2 2.13104
NPTX1 neuronal pentraxin I 2.11904
FAM229B family with sequence similarity 229, member B 2.11439
MTMR10 myotubularin related protein 10 2.11083
PDAP1 PDGFA associated protein 1 2.10439
UQCC3 ubiquinol-cytochrome c reductase complex assembly factor 3 2.10439
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 2.08321
RFX4 regulatory factor X, 4 (influences HLA class II expression) 2.06428
MEF2C myocyte enhancer factor 2C 2.06306
LMTK1 lemur tail kinase 1 2.06129
PARS2 prolyl-tRNA synthetase 2, mitochondrial (putative) 2.06064
UBAP2L ubiquitin associated protein 2-like 2.05676
TRIAP1 TP53 regulated inhibitor of apoptosis 1 2.05174
NISCH nischarin 2.04974
PICK1 protein interacting with PRKCA 1 2.04974
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 2.04974
ZC3H12C zinc finger CCCH-type containing 12C 2.04713
TBL1X transducin (beta)-like 1X-linked 2.00344

decreased expression

Symbol Name Standardized Value
ZNF610 zinc finger protein 610 -2.7521
TRMT10A tRNA methyltransferase 10 homolog A (S. cerevisiae) -2.7521
IL32 interleukin 32 -2.7521
ASB18 ankyrin repeat and SOCS box containing 18 -2.7521
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) -2.7521
TESK1 testis-specific kinase 1 -2.7521
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B -2.7521
PSORS1C1 psoriasis susceptibility 1 candidate 1 -2.7521
FCN3 ficolin (collagen/fibrinogen domain containing) 3 -2.7521
LOC390937 Ets2 repressor factor-like -2.7521
SIX1 SIX homeobox 1 -2.7521
LPA lipoprotein, Lp(a) -2.7521
ADGRB1 adhesion G protein-coupled receptor B1 -2.7521
PAX5 paired box 5 -2.7521
DPPA3 developmental pluripotency associated 3 -2.7521
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -2.7521
RPL3L ribosomal protein L3-like -2.7521
PDE3B phosphodiesterase 3B, cGMP-inhibited -2.7521
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 -2.7521
FAM221B family with sequence similarity 221, member B -2.7521
NPIPB9 nuclear pore complex interacting protein family, member B9 -2.7521
HCRTR2 hypocretin (orexin) receptor 2 -2.7521
PCDHGA12 protocadherin gamma subfamily A, 12 -2.7521
CCDC110 coiled-coil domain containing 110 -2.7521
NPIPB15 nuclear pore complex interacting protein family, member B15 -2.7521
NCAPG2 non-SMC condensin II complex, subunit G2 -2.7521
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) -2.7521
SMIM38 small integral membrane protein 38 -2.7521
LRRC8E leucine rich repeat containing 8 family, member E -2.7521
TEX19 testis expressed 19 -2.7521
LRRC19 leucine rich repeat containing 19 -2.7521
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1 -2.7521
GALNT17 polypeptide N-acetylgalactosaminyltransferase 17 -2.7521
ADAM18 ADAM metallopeptidase domain 18 -2.7521
WNT4 wingless-type MMTV integration site family, member 4 -2.7521
KLK14 kallikrein-related peptidase 14 -2.7521
CTRL chymotrypsin-like -2.7521
KLF4 Kruppel-like factor 4 (gut) -2.7521
BNC1 basonuclin 1 -2.7521
ZNF703 zinc finger protein 703 -2.7521
VN1R1 vomeronasal 1 receptor 1 -2.7521
ANKRD61 ankyrin repeat domain 61 -2.7521
FAM24B family with sequence similarity 24, member B -2.7521
B3GAT3 beta-1,3-glucuronyltransferase 3 -2.73044
FRMPD3 FERM and PDZ domain containing 3 -2.68461
DST dystonin -2.684
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 -2.63636
ENKUR enkurin, TRPC channel interacting protein -2.63636
SLC67A1 solute carrier family 67 member 1 -2.62556
RIBC2 RIB43A domain with coiled-coils 2 -2.62556
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase -2.62556
RABGGTA Rab geranylgeranyltransferase, alpha subunit -2.62556
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha -2.62372
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog -2.56743
ECT2 epithelial cell transforming 2 -2.53517
PRXL2A peroxiredoxin like 2A -2.51151
MFN2 mitofusin 2 -2.50006
RPA3 replication protein A3, 14kDa -2.46056
CHRM5 cholinergic receptor, muscarinic 5 -2.38625
STAP2 signal transducing adaptor family member 2 -2.37636
SESTD1 SEC14 and spectrin domains 1 -2.3471
TTK TTK protein kinase -2.3153
ZNF561 zinc finger protein 561 -2.31241
RHOBTB3 Rho-related BTB domain containing 3 -2.21994
WWTR1 WW domain containing transcription regulator 1 -2.21589
AMOT angiomotin -2.2144
NIPAL3 NIPA-like domain containing 3 -2.2016
CHN1 chimerin 1 -2.2002
REDIC1 regulator of DNA class I crossover intermediates 1 -2.19195
CST3 cystatin C -2.1732
TSPAN9 tetraspanin 9 -2.16479
KIAA0040 KIAA0040 -2.16479
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2 -2.15313
PRSS27 protease, serine 27 -2.15313
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae) -2.14388
ZDHHC9 zinc finger, DHHC-type containing 9 -2.13104
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 -2.12875
SPA17 sperm autoantigenic protein 17 -2.12836
ICMT isoprenylcysteine carboxyl methyltransferase -2.12239
DUSP28 dual specificity phosphatase 28 -2.11112
DLEC1 deleted in lung and esophageal cancer 1 -2.11112
WDR5B WD repeat domain 5B -2.11112
FTO fat mass and obesity associated -2.09018
GTSE1 G-2 and S-phase expressed 1 -2.06306
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 -2.0619
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 -2.0619
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 -2.06064
GEMIN4 gem (nuclear organelle) associated protein 4 -2.06064
CCAR2 cell cycle and apoptosis regulator 2 -2.06064
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 -2.04974
PKP2 plakophilin 2 -2.04974
RORB RAR-related orphan receptor B -2.04419
VEGFA vascular endothelial growth factor A -2.04419
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -2.01513
ATP6V1E2 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2 -2.01139