NUP54 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description nucleoporin 54kDa|The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. This gene encodes a member of the phe-gly (FG) repeat-containing nucleoporin subset. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013] (NCBI Entrez Gene Database, 53371)
External Link https://ncbi.nlm.nih.gov/gene/53371
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Genes

497 genes differentially expressed following the NUP54 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
MYBPC1 myosin binding protein C, slow type 0.0174985
NPIPB3 nuclear pore complex interacting protein family, member B3 0.0160956
RGS5 regulator of G-protein signaling 5 0.0155889
ASPN asporin 0.0149678
FHL1 four and a half LIM domains 1 0.0148338
AKAP12 A kinase (PRKA) anchor protein 12 0.0146207
MBD1 methyl-CpG binding domain protein 1 0.0144518
S100P S100 calcium binding protein P 0.0140703
COG7 component of oligomeric golgi complex 7 0.013526
EIF5A eukaryotic translation initiation factor 5A 0.0134751
GNAS GNAS complex locus 0.0127488
SPRED2 sprouty-related, EVH1 domain containing 2 0.0127439
CCN2 cellular communication network factor 2 0.0123949
ABLIM1 actin binding LIM protein 1 0.012247
OGN osteoglycin 0.0122098
FABP7 fatty acid binding protein 7, brain 0.0121027
ZNF91 zinc finger protein 91 0.0120493
THBS4 thrombospondin 4 0.0119966
TNNC1 troponin C type 1 (slow) 0.0117993
FABP4 fatty acid binding protein 4, adipocyte 0.0116834
HSPH1 heat shock 105kDa/110kDa protein 1 0.0113305
PEG10 paternally expressed 10 0.0112867
BMP2 bone morphogenetic protein 2 0.0106163
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 0.0105388
MGP matrix Gla protein 0.0105225
CXCL12 chemokine (C-X-C motif) ligand 12 0.0105107
SFRP1 secreted frizzled-related protein 1 0.010388
CXCL8 chemokine (C-X-C motif) ligand 8 0.0102814
MFAP4 microfibrillar-associated protein 4 0.0102635
METRN meteorin, glial cell differentiation regulator 0.0101659
SFRP4 secreted frizzled-related protein 4 0.00995024
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.00994055
SRPX sushi-repeat containing protein, X-linked 0.0099376
BEX1 brain expressed, X-linked 1 0.00990914
RFTN1 raftlin, lipid raft linker 1 0.00990459
FILIP1L filamin A interacting protein 1-like 0.00982094
PTN pleiotrophin 0.00977058
LAMA2 laminin, alpha 2 0.00967033
CRYAB crystallin, alpha B 0.00966746
MTUS1 microtubule associated tumor suppressor 1 0.00959493
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.00954567
CFD complement factor D (adipsin) 0.00953053
FBN2 fibrillin 2 0.00946816
RET ret proto-oncogene 0.00939525
S100A7 S100 calcium binding protein A7 0.0093803
TNNC2 troponin C type 2 (fast) 0.00932146
AREG amphiregulin 0.00930781
CNTN1 contactin 1 0.00923177
FSTL1 follistatin-like 1 0.0091306
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 0.00912447
CXCL2 chemokine (C-X-C motif) ligand 2 0.00909946
RTN2 reticulon 2 0.00906099
TTN titin 0.00904214
PDGFRL platelet-derived growth factor receptor-like 0.00898607
PXDN peroxidasin 0.00884613
SAMD4A sterile alpha motif domain containing 4A 0.00883156
CAVIN2 caveolae associated protein 2 0.00883119
SORBS1 sorbin and SH3 domain containing 1 0.00882591
PADI2 peptidyl arginine deiminase, type II 0.00879767
KLHL41 kelch-like family member 41 0.00878044
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.00868222
FBLN5 fibulin 5 0.00862364
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.00861195
ACTA1 actin, alpha 1, skeletal muscle 0.00861018
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.0085956
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 0.00858812
VCL vinculin 0.00857339
CCNA2 cyclin A2 0.0085694
GPX1 glutathione peroxidase 1 0.00853516
ARHGAP29 Rho GTPase activating protein 29 0.00852716
MFAP5 microfibrillar associated protein 5 0.00852136
CKM creatine kinase, muscle 0.00850352
PNMA2 paraneoplastic Ma antigen 2 0.00848039
IL6ST interleukin 6 signal transducer 0.00846969
DACH1 dachshund family transcription factor 1 0.00845935
TPM2 tropomyosin 2 (beta) 0.00845406
AGR2 anterior gradient 2 0.00844934
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.00841186
HSPB8 heat shock 22kDa protein 8 0.00840761
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0083954
COL14A1 collagen, type XIV, alpha 1 0.0083728
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.00833674
TSPAN8 tetraspanin 8 0.00833445
SELE selectin E 0.00832061
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.00830865
SPARCL1 SPARC-like 1 (hevin) 0.00830176
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.00829273
ITM2A integral membrane protein 2A 0.00827562
DMTF1 cyclin D binding myb-like transcription factor 1 0.0082422
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.00821512
PI3 peptidase inhibitor 3, skin-derived 0.00813549
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 0.00808837
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.00808399
ACTG2 actin, gamma 2, smooth muscle, enteric 0.00806091
CDV3 CDV3 homolog (mouse) 0.00804361
NT5C2 5'-nucleotidase, cytosolic II 0.0079953
TRIM16 tripartite motif containing 16 0.00798775
A2M alpha-2-macroglobulin 0.00796973
MYL1 myosin, light chain 1, alkali; skeletal, fast 0.00793548
SYNM synemin, intermediate filament protein 0.00791283
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.00790969
ANXA3 annexin A3 0.00790949
DST dystonin 0.00789565
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.00788658
COL9A3 collagen, type IX, alpha 3 0.00785664
MT1E metallothionein 1E 0.0077981
TAGLN transgelin 0.00779415
TPM3 tropomyosin 3 0.00777468
TTC39A tetratricopeptide repeat domain 39A 0.00775443
TJP2 tight junction protein 2 0.00774025
TACC1 transforming, acidic coiled-coil containing protein 1 0.00773848
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 0.00770398
KLF6 Kruppel-like factor 6 0.00770306
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00763483
GOLGA8A golgin A8 family, member A 0.00760881
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.00760656
FGFR1 fibroblast growth factor receptor 1 0.00757091
PODXL podocalyxin-like 0.00756759
DCN decorin 0.00756277
CELF2 CUGBP, Elav-like family member 2 0.00755349
ATF3 activating transcription factor 3 0.00755049
NAV2 neuron navigator 2 0.00750288
NEBL nebulette 0.00748655
FBN1 fibrillin 1 0.00747886
TENT5A terminal nucleotidyltransferase 5A 0.00747736
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.00747684
MMP3 matrix metallopeptidase 3 0.00747158
PLS3 plastin 3 0.00743701
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 0.00742213
CES1 carboxylesterase 1 0.00739405
ABLIM3 actin binding LIM protein family, member 3 0.0073913
RBM26 RNA binding motif protein 26 0.00736762
BMP4 bone morphogenetic protein 4 0.00736195
FMO2 flavin containing monooxygenase 2 (non-functional) 0.00734139
TGFB3 transforming growth factor, beta 3 0.00732277
LHFP lipoma HMGIC fusion partner 0.00732175
EPHA2 EPH receptor A2 0.00731451
RBMS1 RNA binding motif, single stranded interacting protein 1 0.00729463
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae) 0.007277
SPINK1 serine peptidase inhibitor, Kazal type 1 0.00726216
LDB3 LIM domain binding 3 0.00724576
TOX thymocyte selection-associated high mobility group box 0.00722814
XIC X chromosome inactivation center 0.00719479
RELN reelin 0.00719269
MARCKS myristoylated alanine-rich protein kinase C substrate 0.00716875
PLK2 polo-like kinase 2 0.00715136
ZNF160 zinc finger protein 160 0.00714734
MEG3 maternally expressed 3 (non-protein coding) 0.00712529
TESC tescalcin 0.00712443
KDSR 3-ketodihydrosphingosine reductase 0.00710931
ZEB1 zinc finger E-box binding homeobox 1 0.00704756
IFI27 interferon, alpha-inducible protein 27 0.00703477
MPHOSPH8 M-phase phosphoprotein 8 0.00702144
CASQ2 calsequestrin 2 (cardiac muscle) 0.0070171
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 0.00700395
DES desmin 0.00700056
MYOZ2 myozenin 2 0.00696998
ANK2 ankyrin 2, neuronal 0.00695494
USP47 ubiquitin specific peptidase 47 0.00692987
PAMR1 peptidase domain containing associated with muscle regeneration 1 0.00692697
GRK5 G protein-coupled receptor kinase 5 0.00692425
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 0.00691803
OSBPL1A oxysterol binding protein-like 1A 0.00689592
GUSBP3 glucuronidase, beta pseudogene 3 0.00688783
APOD apolipoprotein D 0.00688399
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 0.00688258
LUM lumican 0.00687816
ANKRD11 ankyrin repeat domain 11 0.00685158
SPRY2 sprouty homolog 2 (Drosophila) 0.0068465
STC2 stanniocalcin 2 0.00682857
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.006818
MAOB monoamine oxidase B 0.00681558
NFIB nuclear factor I/B 0.00680137
JAM2 junctional adhesion molecule 2 0.00680006
PLAAT3 phospholipase A and acyltransferase 3 0.00679537
MCM2 minichromosome maintenance complex component 2 0.00677828
MGLL monoglyceride lipase 0.00676068
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.00676011
PDE8B phosphodiesterase 8B 0.00672965
ASCL1 achaete-scute family bHLH transcription factor 1 0.0067229
RGCC regulator of cell cycle 0.00672068
GPRC5B G protein-coupled receptor, class C, group 5, member B 0.00670298
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00668945
IGF1 insulin-like growth factor 1 (somatomedin C) 0.00667426
PEBP1 phosphatidylethanolamine binding protein 1 0.0066709
RNF125 ring finger protein 125, E3 ubiquitin protein ligase 0.0066548
GPC3 glypican 3 0.00662321
IFRD1 interferon-related developmental regulator 1 0.00660706
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.00659407
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.00658799
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00656567
FMOD fibromodulin 0.00656183
RBPMS RNA binding protein with multiple splicing 0.00654151
SSPN sarcospan 0.00653418
C1S complement component 1, s subcomponent 0.00652441
OGA O-GlcNAcase 0.00651966
NOLC1 nucleolar and coiled-body phosphoprotein 1 0.00650514
ACTN2 actinin, alpha 2 0.00648829
ADIPOQ adiponectin, C1Q and collagen domain containing 0.00646184
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.00645869
TNNI1 troponin I type 1 (skeletal, slow) 0.00645166
LIPG lipase, endothelial 0.00643727
ADAM12 ADAM metallopeptidase domain 12 0.00643188
ABAT 4-aminobutyrate aminotransferase 0.00642191
TUBB2B tubulin, beta 2B class IIb 0.00641941
APOLD1 apolipoprotein L domain containing 1 0.00641521
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.00641486
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa 0.00640547
MAB21L2 mab-21-like 2 (C. elegans) 0.0063989
FGF1 fibroblast growth factor 1 (acidic) 0.00638607
RGS1 regulator of G-protein signaling 1 0.00638536
MKNK2 MAP kinase interacting serine/threonine kinase 2 0.00638102
ZFHX4 zinc finger homeobox 4 0.00635569
MAGT1 magnesium transporter 1 0.00634775
GABARAPL1 GABA(A) receptor-associated protein like 1 0.00634659
MYOM1 myomesin 1 0.00634006
AZU1 azurocidin 1 0.00632798
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.00632081
MPO myeloperoxidase 0.00631633
PLCB4 phospholipase C, beta 4 0.00631369
CD93 CD93 molecule 0.00629285
DPT dermatopontin 0.00627347
MTCL1 microtubule crosslinking factor 1 0.00625091
PLIN3 perilipin 3 0.0062459
TFF1 trefoil factor 1 0.00624119
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 0.00622738
ZNF430 zinc finger protein 430 0.00622367
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.00620895
MAB21L1 mab-21-like 1 (C. elegans) 0.00620874
STOM stomatin 0.00620733
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.00617984
PHACTR4 phosphatase and actin regulator 4 0.00617517
TM4SF1 transmembrane 4 L six family member 1 0.00615068
LIMCH1 LIM and calponin homology domains 1 0.0061487
SWAP70 SWAP switching B-cell complex 70kDa subunit 0.00614123
FAR2 fatty acyl CoA reductase 2 0.00613863
XPO7 exportin 7 0.00613726
GADD45B growth arrest and DNA-damage-inducible, beta 0.00613429
CTSG cathepsin G 0.00612404
RSL1D1 ribosomal L1 domain containing 1 0.00611576
F2R coagulation factor II (thrombin) receptor 0.00610969
CRY1 cryptochrome circadian clock 1 0.006097
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00609625
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00609306
DYNLL1 dynein, light chain, LC8-type 1 0.00609248
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 0.00607297
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.00604236
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle 0.0060414
PDE4DIP phosphodiesterase 4D interacting protein 0.00603081
RNF167 ring finger protein 167 0.00602811

decreased expression

Symbol Name Standardized Value
CDCA4 cell division cycle associated 4 -0.0171674
CD40 CD40 molecule, TNF receptor superfamily member 5 -0.0152698
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.0150747
CA12 carbonic anhydrase XII -0.0145422
S100A9 S100 calcium binding protein A9 -0.0143385
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.0132474
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -0.0130647
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -0.0127499
CXCL10 chemokine (C-X-C motif) ligand 10 -0.0119654
S100A8 S100 calcium binding protein A8 -0.0119052
TGFBI transforming growth factor, beta-induced, 68kDa -0.0116604
WT1 Wilms tumor 1 -0.0109741
ALOX5 arachidonate 5-lipoxygenase -0.0107168
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.0105385
GRB7 growth factor receptor-bound protein 7 -0.0104714
HP haptoglobin -0.0104185
PRAME preferentially expressed antigen in melanoma -0.0102217
CTSH cathepsin H -0.00970077
HOXC6 homeobox C6 -0.00962926
LEF1 lymphoid enhancer-binding factor 1 -0.00961774
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 -0.0096085
ANPEP alanyl (membrane) aminopeptidase -0.00960266
SSBP2 single-stranded DNA binding protein 2 -0.00941392
TPD52L1 tumor protein D52-like 1 -0.00941125
SNX10 sorting nexin 10 -0.00927134
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) -0.00922179
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.00918348
CPB1 carboxypeptidase B1 (tissue) -0.00912455
QPCT glutaminyl-peptide cyclotransferase -0.00911483
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) -0.00903351
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.00896637
SELENBP1 selenium binding protein 1 -0.0089636
NMU neuromedin U -0.00889351
CP ceruloplasmin (ferroxidase) -0.00886994
ANXA4 annexin A4 -0.00882909
TDO2 tryptophan 2,3-dioxygenase -0.00880511
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.00875896
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O -0.00874816
RXRA retinoid X receptor, alpha -0.00872136
SHROOM2 shroom family member 2 -0.00851953
PPA2 pyrophosphatase (inorganic) 2 -0.00850203
NUSAP1 nucleolar and spindle associated protein 1 -0.00847229
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -0.00833094
FGFR3 fibroblast growth factor receptor 3 -0.00833032
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00831782
LY6E lymphocyte antigen 6 complex, locus E -0.00828282
CDC20 cell division cycle 20 -0.0082265
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G -0.00822322
CHN1 chimerin 1 -0.00822291
TGFB1 transforming growth factor, beta 1 -0.00821098
SEPP1 selenoprotein P, plasma, 1 -0.00816281
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) -0.00815136
CDH3 cadherin 3, type 1, P-cadherin (placental) -0.00806271
TPSAB1 tryptase alpha/beta 1 -0.00798679
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00795318
ATP10D ATPase, class V, type 10D -0.00792947
PKM pyruvate kinase, muscle -0.0079021
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00784019
TRIB2 tribbles pseudokinase 2 -0.00783511
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.00782398
NRGN neurogranin (protein kinase C substrate, RC3) -0.00782377
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) -0.00779136
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -0.0077696
CXCL11 chemokine (C-X-C motif) ligand 11 -0.0077156
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) -0.00769632
PLIN2 perilipin 2 -0.00768808
PID1 phosphotyrosine interaction domain containing 1 -0.0076644
GPNMB glycoprotein (transmembrane) nmb -0.00761537
VCAM1 vascular cell adhesion molecule 1 -0.00759201
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -0.00757291
CHN2 chimerin 2 -0.00754464
CXCL9 chemokine (C-X-C motif) ligand 9 -0.00751775
AQP9 aquaporin 9 -0.00751606
PON3 paraoxonase 3 -0.00751332
PDLIM4 PDZ and LIM domain 4 -0.00751268
TMEM176B transmembrane protein 176B -0.00736754
CENPU centromere protein U -0.00732033
EMP3 epithelial membrane protein 3 -0.00729996
RIPK4 receptor-interacting serine-threonine kinase 4 -0.00728466
IDO1 indoleamine 2,3-dioxygenase 1 -0.00722292
NVL nuclear VCP-like -0.00721095
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 -0.00718529
S100A12 S100 calcium binding protein A12 -0.00717478
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 -0.0071482
PRKACB protein kinase, cAMP-dependent, catalytic, beta -0.0070747
HLA-DOB major histocompatibility complex, class II, DO beta -0.00707426
AHNAK2 AHNAK nucleoprotein 2 -0.00705068
HSDL2 hydroxysteroid dehydrogenase like 2 -0.00705036
S100A2 S100 calcium binding protein A2 -0.00703403
LAPTM4B lysosomal protein transmembrane 4 beta -0.00702554
EPHA4 EPH receptor A4 -0.00698228
HBB hemoglobin, beta -0.00694854
IL7 interleukin 7 -0.00692815
GRAMD4 GRAM domain containing 4 -0.00692527
IGSF6 immunoglobulin superfamily, member 6 -0.00689665
MAPK6 mitogen-activated protein kinase 6 -0.00685429
MARCHF1 membrane associated ring-CH-type finger 1 -0.00683096
RAB13 RAB13, member RAS oncogene family -0.00682646
SDC2 syndecan 2 -0.00682267
TCTA T-cell leukemia translocation altered -0.00680438
GSTA4 glutathione S-transferase alpha 4 -0.00678665
ZNF395 zinc finger protein 395 -0.00678427
ACP3 acid phosphatase 3 -0.00672983
GJB1 gap junction protein, beta 1, 32kDa -0.00671614
ACP5 acid phosphatase 5, tartrate resistant -0.00670857
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta -0.00670532
CALML3 calmodulin-like 3 -0.00669782
C11ORF71 chromosome 11 open reading frame 71 -0.00669375
CLEC7A C-type lectin domain family 7, member A -0.0066845
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) -0.00666622
LGALS2 lectin, galactoside-binding, soluble, 2 -0.00662028
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 -0.00660036
IGFBP1 insulin-like growth factor binding protein 1 -0.00659142
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -0.00659056
RRAGA Ras-related GTP binding A -0.0065768
MAGEA3 melanoma antigen family A3 -0.00657285
ING2 inhibitor of growth family, member 2 -0.00657246
TFEC transcription factor EC -0.00656739
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 -0.00656542
FXYD2 FXYD domain containing ion transport regulator 2 -0.00655979
PCP4 Purkinje cell protein 4 -0.00655456
FKBP4 FK506 binding protein 4, 59kDa -0.00654138
TWF1 twinfilin actin binding protein 1 -0.00653562
GSTO1 glutathione S-transferase omega 1 -0.00653513
CCL13 chemokine (C-C motif) ligand 13 -0.00652919
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase -0.00647936
HBD hemoglobin, delta -0.00644967
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00641988
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -0.00641624
ARFIP1 ADP-ribosylation factor interacting protein 1 -0.00639982
NPTX2 neuronal pentraxin II -0.00636299
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) -0.0063329
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 -0.00632937
SSBP3 single stranded DNA binding protein 3 -0.00632368
GRB14 growth factor receptor-bound protein 14 -0.00632364
PIR pirin (iron-binding nuclear protein) -0.00632179
PDGFC platelet derived growth factor C -0.00632022
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) -0.00631972
FTH1 ferritin, heavy polypeptide 1 -0.00631956
HMGN4 high mobility group nucleosomal binding domain 4 -0.0063167
HNMT histamine N-methyltransferase -0.00629961
NSG1 neuron specific gene family member 1 -0.00629582
HLA-DMB major histocompatibility complex, class II, DM beta -0.00629574
AZF1 azoospermia factor 1 -0.00627262
FPR3 formyl peptide receptor 3 -0.00625408
SIDT2 SID1 transmembrane family, member 2 -0.00622037
MDFIC MyoD family inhibitor domain containing -0.00621145
COMT catechol-O-methyltransferase -0.00620858
MMP9 matrix metallopeptidase 9 -0.00620467
SATB2 SATB homeobox 2 -0.00618584
CRIP2 cysteine-rich protein 2 -0.00616194
ACSM3 acyl-CoA synthetase medium-chain family member 3 -0.00615411
GSTA1 glutathione S-transferase alpha 1 -0.00615142
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 -0.00613035
TRIM2 tripartite motif containing 2 -0.00611909
PGAP3 post-GPI attachment to proteins 3 -0.006085
DEPTOR DEP domain containing MTOR-interacting protein -0.00607898
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 -0.00606738
TMEM106C transmembrane protein 106C -0.00606211
FCN1 ficolin (collagen/fibrinogen domain containing) 1 -0.00606035
MCUB mitochondrial calcium uniporter dominant negative subunit beta -0.00603681
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha -0.0060025
ALG6 ALG6, alpha-1,3-glucosyltransferase -0.0059932
SFN stratifin -0.00599169
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 -0.00598656
CTSZ cathepsin Z -0.00597814
FKBP1B FK506 binding protein 1B, 12.6 kDa -0.00596966
NEK2 NIMA-related kinase 2 -0.00595233
ACSL1 acyl-CoA synthetase long-chain family member 1 -0.00594922
CNOT4 CCR4-NOT transcription complex, subunit 4 -0.0059437
RAPSN receptor-associated protein of the synapse -0.00593933
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 -0.0059339
RACGAP1 Rac GTPase activating protein 1 -0.00593382
HIST3H2A histone cluster 3, H2a -0.00592616
ENC1 ectodermal-neural cortex 1 (with BTB domain) -0.0059238
DAPK1 death-associated protein kinase 1 -0.0059182
H1-2 H1.2 linker histone, cluster member -0.00589509
PLBD1 phospholipase B domain containing 1 -0.0058912
TMEM106B transmembrane protein 106B -0.00589029
CRYM crystallin, mu -0.00588833
IRF2 interferon regulatory factor 2 -0.00588414
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 -0.00588252
CRYL1 crystallin, lambda 1 -0.00588078
TSC22D1 TSC22 domain family, member 1 -0.00587721
RNF19B ring finger protein 19B -0.00587656
PTMS parathymosin -0.00587333
MPC2 mitochondrial pyruvate carrier 2 -0.00584957
CCL8 chemokine (C-C motif) ligand 8 -0.00584701
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) -0.00583911
SAP30 Sin3A-associated protein, 30kDa -0.00583477
HOXD1 homeobox D1 -0.00582371
CTSD cathepsin D -0.00580967
TMEM134 transmembrane protein 134 -0.00580949
EML3 echinoderm microtubule associated protein like 3 -0.00580656
PKP1 plakophilin 1 -0.00580611
OSBPL3 oxysterol binding protein-like 3 -0.00580546
MUC4 mucin 4, cell surface associated -0.0057882
CD58 CD58 molecule -0.00576035
S100A4 S100 calcium binding protein A4 -0.00575837
GAS2L1 growth arrest-specific 2 like 1 -0.00574981
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.00574892
TNC tenascin C -0.00574833
MEST mesoderm specific transcript -0.00573809
EREG epiregulin -0.00573081
CYFIP2 cytoplasmic FMR1 interacting protein 2 -0.00571342
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 -0.00571331
CPA3 carboxypeptidase A3 (mast cell) -0.00570982
HDDC2 HD domain containing 2 -0.00570201
PRDX4 peroxiredoxin 4 -0.00569046
SLC38A6 solute carrier family 38, member 6 -0.00566882
ACOT13 acyl-CoA thioesterase 13 -0.00566629
COL1A2 collagen, type I, alpha 2 -0.00565321
GNG10 guanine nucleotide binding protein (G protein), gamma 10 -0.00564793
ZCCHC10 zinc finger, CCHC domain containing 10 -0.0056391
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 -0.00562794
CSTA cystatin A (stefin A) -0.00562582
ZFP36L1 ZFP36 ring finger protein-like 1 -0.00559557
TOB1 transducer of ERBB2, 1 -0.0055943
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -0.00559264
MPP1 membrane protein, palmitoylated 1, 55kDa -0.00558997
EPHX2 epoxide hydrolase 2, cytoplasmic -0.0055823
KYNU kynureninase -0.00558128
KRT6B keratin 6B, type II -0.00557324
FAM13A family with sequence similarity 13, member A -0.00555187
COL18A1 collagen, type XVIII, alpha 1 -0.00554982
FGG fibrinogen gamma chain -0.0055486
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa -0.00554507
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa -0.00554279
EFNA4 ephrin-A4 -0.00553595
BCL7B B-cell CLL/lymphoma 7B -0.00553241
AMD1 adenosylmethionine decarboxylase 1 -0.00551087
GPC1 glypican 1 -0.00550985
CDHR1 cadherin-related family member 1 -0.00550527
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) -0.00549678
NDRG1 N-myc downstream regulated 1 -0.00549371
PLXNB2 plexin B2 -0.00548906
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -0.00548613
CPVL carboxypeptidase, vitellogenic-like -0.00548416
CLEC2B C-type lectin domain family 2, member B -0.00548326
PTK2B protein tyrosine kinase 2 beta -0.00547727
USP3 ubiquitin specific peptidase 3 -0.00547066
NPTN neuroplastin -0.00547016
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) -0.00546996
CORO1B coronin, actin binding protein, 1B -0.00546486
CLCA2 chloride channel accessory 2 -0.00546232
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 -0.00546218
PAN2 PAN2 poly(A) specific ribonuclease subunit -0.00545443