| Dataset | CM4AI KOLF21J CRISPRi Gene Perturbation Atlas |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | nucleoporin 62kDa|The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins and is localized to the nuclear pore central plug. This protein associates with the importin alpha/beta complex which is involved in the import of proteins containing nuclear localization signals. Multiple transcript variants of this gene encode a single protein isoform. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 23636) |
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186 genes differentially expressed following the NUP62 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.
| Symbol | Name | Standardized Value |
|---|---|---|
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | 2.24323 |
| FSBP | fibrinogen silencer binding protein | 2.24323 |
| PTGR3 | prostaglandin reductase 3 | 2.24323 |
| EPC1 | enhancer of polycomb homolog 1 (Drosophila) | 2.24323 |
| DMRTA1 | DMRT-like family A1 | 2.24323 |
| NPHP1 | nephronophthisis 1 (juvenile) | 2.24323 |
| KIF5A | kinesin family member 5A | 2.24323 |
| VIL1 | villin 1 | 2.24323 |
| MROH1 | maestro heat-like repeat family member 1 | 2.24323 |
| GPR156 | G protein-coupled receptor 156 | 2.23476 |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 | 2.23476 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | 2.23476 |
| CDH7 | cadherin 7, type 2 | 2.23476 |
| DCUN1D3 | DCN1, defective in cullin neddylation 1, domain containing 3 | 2.23476 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 | 2.23476 |
| NPY5R | neuropeptide Y receptor Y5 | 2.23476 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 2.23476 |
| MGARP | mitochondria-localized glutamic acid-rich protein | 2.23476 |
| ZNF610 | zinc finger protein 610 | 2.23476 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | 2.23476 |
| MARCHF8 | membrane associated ring-CH-type finger 8 | 2.23476 |
| MVP | major vault protein | 2.23476 |
| H2BC5 | H2B clustered histone 5 | 2.23476 |
| ETFRF1 | electron transfer flavoprotein regulatory factor 1 | 2.23476 |
| BORCS6 | BLOC-1 related complex subunit 6 | 2.23476 |
| SEMA4F | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F | 2.23476 |
| MLPH | melanophilin | 2.23476 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase | 2.23476 |
| ANKRD13D | ankyrin repeat domain 13 family, member D | 2.23476 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa | 2.23476 |
| WSCD1 | WSC domain containing 1 | 2.23476 |
| NKX3-1 | NK3 homeobox 1 | 2.23476 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 2.23476 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | 2.23476 |
| ZNF19 | zinc finger protein 19 | 2.23476 |
| HARBI1 | harbinger transposase derived 1 | 2.23476 |
| CFAP58 | cilia and flagella associated protein 58 | 2.23476 |
| ZNF114 | zinc finger protein 114 | 2.23476 |
| LRIG3 | leucine-rich repeats and immunoglobulin-like domains 3 | 2.23476 |
| SLC51A | solute carrier family 51, alpha subunit | 2.23476 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 2.23476 |
| STK16 | serine/threonine kinase 16 | 2.23476 |
| C6ORF163 | chromosome 6 open reading frame 163 | 2.23476 |
| ESYT2 | extended synaptotagmin-like protein 2 | 2.23476 |
| RCOR2 | REST corepressor 2 | 2.23476 |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) | 2.23476 |
| CEL | carboxyl ester lipase | 2.23476 |
| MLXIPL | MLX interacting protein-like | 2.23476 |
| ZNF112 | zinc finger protein 112 | 2.23476 |
| ENHO | energy homeostasis associated | 2.23476 |
| TMEM222 | transmembrane protein 222 | 2.23476 |
| IDNK | idnK, gluconokinase homolog (E. coli) | 2.23476 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | 2.23476 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 2.23476 |
| CAB39L | calcium binding protein 39-like | 2.23476 |
| WNT5B | wingless-type MMTV integration site family, member 5B | 2.23476 |
| MLKL | mixed lineage kinase domain-like | 2.23476 |
| SLC10A3 | solute carrier family 10, member 3 | 2.22491 |
| SHROOM2 | shroom family member 2 | 2.22491 |
| ELOVL6 | ELOVL fatty acid elongase 6 | 2.22491 |
| RDX | radixin | 2.22491 |
| SNRPD1 | small nuclear ribonucleoprotein D1 polypeptide 16kDa | 2.22491 |
| AUNIP | aurora kinase A and ninein interacting protein | 2.22491 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 | 2.22491 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 | 2.22491 |
| PPP1R1C | protein phosphatase 1, regulatory (inhibitor) subunit 1C | 2.22491 |
| COQ5 | coenzyme Q5 homolog, methyltransferase (S. cerevisiae) | 2.22491 |
| CCDC157 | coiled-coil domain containing 157 | 2.22491 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 2.22491 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 | 2.18787 |
| DCLK2 | doublecortin-like kinase 2 | 2.18787 |
| METTL18 | methyltransferase like 18 | 2.18787 |
| SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 | 2.18787 |
| HS1BP3 | HCLS1 binding protein 3 | 2.18787 |
| GTF2H1 | general transcription factor IIH, polypeptide 1, 62kDa | 2.18787 |
| XTBD1 | XRN2 binding domain containing 1 | 2.14847 |
| CENPH | centromere protein H | 2.14847 |
| RMDN3 | regulator of microtubule dynamics 3 | 2.14272 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 | 2.14058 |
| TBC1D13 | TBC1 domain family, member 13 | 2.14058 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 2.11135 |
| FBXL15 | F-box and leucine-rich repeat protein 15 | 2.11135 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 2.02944 |
| GIPC2 | GIPC PDZ domain containing family, member 2 | 2.01322 |
| RNF166 | ring finger protein 166 | 2.01322 |
| GALNT8 | polypeptide N-acetylgalactosaminyltransferase 8 | 2.00969 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MRPL39 | mitochondrial ribosomal protein L39 | -2.24323 |
| MUS81 | MUS81 structure-specific endonuclease subunit | -2.24323 |
| SMYD5 | SMYD family member 5 | -2.24323 |
| MAP2K3 | mitogen-activated protein kinase kinase 3 | -2.24323 |
| NT5C | 5', 3'-nucleotidase, cytosolic | -2.24323 |
| PCYOX1L | prenylcysteine oxidase 1 like | -2.24323 |
| ADAMTS2 | ADAM metallopeptidase with thrombospondin type 1 motif, 2 | -2.24323 |
| TMLHE | trimethyllysine hydroxylase, epsilon | -2.24323 |
| COG2 | component of oligomeric golgi complex 2 | -2.24323 |
| BLACAT1 | bladder cancer associated transcript 1 (non-protein coding) | -2.23476 |
| SAXO6 | stabilizer of axonemal microtubules 6 | -2.23476 |
| EXOSC5 | exosome component 5 | -2.23476 |
| ZNF821 | zinc finger protein 821 | -2.23476 |
| SLC35E3 | solute carrier family 35, member E3 | -2.23476 |
| SLC27A1 | solute carrier family 27 (fatty acid transporter), member 1 | -2.23476 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -2.23476 |
| PAM16 | presequence translocase-associated motor 16 homolog (S. cerevisiae) | -2.23476 |
| MIER2 | mesoderm induction early response 1, family member 2 | -2.23476 |
| RRAS | related RAS viral (r-ras) oncogene homolog | -2.23476 |
| LAMC2 | laminin, gamma 2 | -2.23476 |
| TMEM74 | transmembrane protein 74 | -2.23476 |
| AAAS | achalasia, adrenocortical insufficiency, alacrimia | -2.23476 |
| EPHA4 | EPH receptor A4 | -2.23476 |
| UNC5C | unc-5 homolog C (C. elegans) | -2.23476 |
| TSPAN11 | tetraspanin 11 | -2.23476 |
| UTP23 | UTP23, small subunit (SSU) processome component, homolog (yeast) | -2.22637 |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 | -2.22491 |
| KIAA0319 | KIAA0319 | -2.22491 |
| DCX | doublecortin | -2.22491 |
| THSD7A | thrombospondin, type I, domain containing 7A | -2.22491 |
| ZNF358 | zinc finger protein 358 | -2.22491 |
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 | -2.22491 |
| SP110 | SP110 nuclear body protein | -2.22491 |
| SHB | Src homology 2 domain containing adaptor protein B | -2.22491 |
| SLC43A3 | solute carrier family 43, member 3 | -2.22491 |
| LZTFL1 | leucine zipper transcription factor-like 1 | -2.22491 |
| AMY2B | amylase, alpha 2B (pancreatic) | -2.22491 |
| C16ORF46 | chromosome 16 open reading frame 46 | -2.22491 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -2.22491 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 | -2.22491 |
| SIK1 | salt-inducible kinase 1 | -2.22491 |
| PKD1L2 | polycystic kidney disease 1-like 2 (gene/pseudogene) | -2.22491 |
| NCOA6 | nuclear receptor coactivator 6 | -2.22491 |
| GMEB2 | glucocorticoid modulatory element binding protein 2 | -2.22491 |
| IL17RE | interleukin 17 receptor E | -2.22491 |
| USH1C | Usher syndrome 1C (autosomal recessive, severe) | -2.22491 |
| ADGRG5 | adhesion G protein-coupled receptor G5 | -2.22491 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | -2.22491 |
| CALB1 | calbindin 1, 28kDa | -2.22491 |
| TBCC | tubulin folding cofactor C | -2.22491 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | -2.22491 |
| TMEM52 | transmembrane protein 52 | -2.22491 |
| C11ORF65 | chromosome 11 open reading frame 65 | -2.22491 |
| TCEANC2 | transcription elongation factor A (SII) N-terminal and central domain containing 2 | -2.22491 |
| CCDC7 | coiled-coil domain containing 7 | -2.22491 |
| H2AC11 | H2A clustered histone 11 | -2.22491 |
| SPINK8 | serine peptidase inhibitor, Kazal type 8 (putative) | -2.22491 |
| BTN2A2 | butyrophilin, subfamily 2, member A2 | -2.22491 |
| USP30 | ubiquitin specific peptidase 30 | -2.22491 |
| RASL11B | RAS-like, family 11, member B | -2.22491 |
| CHST13 | carbohydrate (chondroitin 4) sulfotransferase 13 | -2.22491 |
| FAM110B | family with sequence similarity 110, member B | -2.22491 |
| GPR39 | G protein-coupled receptor 39 | -2.22491 |
| CNEP1R1 | CTD nuclear envelope phosphatase 1 regulatory subunit 1 | -2.22491 |
| ZNF391 | zinc finger protein 391 | -2.22491 |
| MYORG | myogenesis regulating glycosidase (putative) | -2.22491 |
| MIGA2 | mitoguardin 2 | -2.22491 |
| ITPKC | inositol-trisphosphate 3-kinase C | -2.22491 |
| PPWD1 | peptidylprolyl isomerase domain and WD repeat containing 1 | -2.20921 |
| URM1 | ubiquitin related modifier 1 | -2.18787 |
| JPH3 | junctophilin 3 | -2.18787 |
| ZDHHC16 | zinc finger, DHHC-type containing 16 | -2.14847 |
| BBS2 | Bardet-Biedl syndrome 2 | -2.14847 |
| HSF2BP | heat shock transcription factor 2 binding protein | -2.14847 |
| C1ORF159 | chromosome 1 open reading frame 159 | -2.14847 |
| H3C7 | H3 clustered histone 7 | -2.14847 |
| CRABP1 | cellular retinoic acid binding protein 1 | -2.14847 |
| ZNF780A | zinc finger protein 780A | -2.14847 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | -2.14847 |
| TNRC18 | trinucleotide repeat containing 18 | -2.14847 |
| CEP44 | centrosomal protein 44kDa | -2.14847 |
| ATG16L2 | autophagy related 16-like 2 (S. cerevisiae) | -2.14847 |
| TSPYL2 | TSPY-like 2 | -2.14847 |
| TSPYL4 | TSPY-like 4 | -2.14847 |
| ZNF611 | zinc finger protein 611 | -2.14847 |
| AGAP9 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 9 | -2.14847 |
| HAUS6 | HAUS augmin-like complex, subunit 6 | -2.14847 |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 | -2.14847 |
| LNP1 | leukemia NUP98 fusion partner 1 | -2.14847 |
| FBN1 | fibrillin 1 | -2.14847 |
| TRMT61A | tRNA methyltransferase 61A | -2.14847 |
| P3H1 | prolyl 3-hydroxylase 1 | -2.14847 |
| RNF213 | ring finger protein 213 | -2.14847 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -2.14272 |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 | -2.13627 |
| NVL | nuclear VCP-like | -2.07366 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -2.06866 |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 | -2.06866 |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) | -2.06642 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | -2.04985 |
