| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NVP-BHG712 perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the NVP-BHG712_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PODXL | podocalyxin-like | 0.123632 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.101748 |
| CDH13 | cadherin 13 | 0.0841347 |
| NDRG1 | N-myc downstream regulated 1 | 0.0690761 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0534538 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0532392 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0524302 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0507966 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0486727 |
| LMNA | lamin A/C | 0.0478635 |
| EGFR | epidermal growth factor receptor | 0.045573 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0439272 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0418492 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0384651 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0377425 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0376638 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0372129 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0366816 |
| CSTB | cystatin B (stefin B) | 0.0364649 |
| FN1 | fibronectin 1 | 0.0354336 |
| FLNA | filamin A, alpha | 0.0352118 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0351109 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0346531 |
| COL5A1 | collagen, type V, alpha 1 | 0.0346157 |
| PLEC | plectin | 0.0344607 |
| ACTG1 | actin gamma 1 | 0.0344585 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0322025 |
| CENPF | centromere protein F, 350/400kDa | 0.031534 |
| HDAC9 | histone deacetylase 9 | 0.0311936 |
| MAP1B | microtubule-associated protein 1B | 0.0303882 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0302377 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0288888 |
| CAVIN1 | caveolae associated protein 1 | 0.0283956 |
| S100A11 | S100 calcium binding protein A11 | 0.0275287 |
| RPL35A | ribosomal protein L35a | 0.0274839 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0267755 |
| TMSB10 | thymosin beta 10 | 0.0266576 |
| RPL37A | ribosomal protein L37a | 0.0257644 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0248271 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0248244 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0247723 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.0231611 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0219949 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.021507 |
| EFNA5 | ephrin-A5 | 0.0214028 |
| PLXNA2 | plexin A2 | 0.0213026 |
| PRSS23 | protease, serine, 23 | 0.0211811 |
| TPM3 | tropomyosin 3 | 0.0210824 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0210082 |
| TPM4 | tropomyosin 4 | 0.0209466 |
| CCND1 | cyclin D1 | 0.0208611 |
| RPL36 | ribosomal protein L36 | 0.0205492 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0204385 |
| RACK1 | receptor for activated C kinase 1 | 0.0202676 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.020253 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0200248 |
| LDHA | lactate dehydrogenase A | 0.0197506 |
| PFN1 | profilin 1 | 0.0196679 |
| KLF6 | Kruppel-like factor 6 | 0.0195249 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0194442 |
| RPS19 | ribosomal protein S19 | 0.0191657 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0191173 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0189606 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0187198 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.018268 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0182553 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0182513 |
| SEPTIN7 | septin 7 | 0.0182309 |
| RPS3 | ribosomal protein S3 | 0.0179882 |
| RPS17 | ribosomal protein S17 | 0.0177723 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0177067 |
| FTL | ferritin, light polypeptide | 0.0175391 |
| SEC61G | Sec61 gamma subunit | 0.0174658 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.0173869 |
| FSTL1 | follistatin-like 1 | 0.017351 |
| TMSB4X | thymosin beta 4, X-linked | 0.0171491 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0171455 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0170289 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0167836 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | 0.0167297 |
| DSPP | dentin sialophosphoprotein | 0.0164568 |
| RPL12 | ribosomal protein L12 | 0.0163043 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0161882 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0161343 |
| RPS12 | ribosomal protein S12 | 0.0159504 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | 0.0153465 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | 0.0153003 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0152982 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.015225 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0151505 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0151322 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0151106 |
| RPL27 | ribosomal protein L27 | 0.0147354 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.0146936 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0146311 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0145554 |
| TPI1 | triosephosphate isomerase 1 | 0.0143197 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0141049 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0139619 |
| TBCA | tubulin folding cofactor A | 0.0137625 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.184076 |
| UBC | ubiquitin C | -0.155006 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.122721 |
| FBN1 | fibrillin 1 | -0.108313 |
| COL3A1 | collagen, type III, alpha 1 | -0.101543 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0919697 |
| COL1A2 | collagen, type I, alpha 2 | -0.0832879 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0626927 |
| COL5A2 | collagen, type V, alpha 2 | -0.0622174 |
| LOX | lysyl oxidase | -0.062091 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0528126 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0516442 |
| OGA | O-GlcNAcase | -0.0483281 |
| CD99 | CD99 molecule | -0.0465154 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0452773 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0446612 |
| CD44 | CD44 molecule (Indian blood group) | -0.0439625 |
| PLAT | plasminogen activator, tissue | -0.0393606 |
| AUTS2 | autism susceptibility candidate 2 | -0.0382853 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.03707 |
| STC1 | stanniocalcin 1 | -0.0367723 |
| SBF2 | SET binding factor 2 | -0.0361345 |
| AHNAK | AHNAK nucleoprotein | -0.0346001 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0327106 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0319108 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0312925 |
| LOXL2 | lysyl oxidase-like 2 | -0.0306433 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0304092 |
| GPC6 | glypican 6 | -0.0290703 |
| APP | amyloid beta (A4) precursor protein | -0.0283759 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0277758 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0270367 |
| ATP13A3 | ATPase type 13A3 | -0.0268992 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.026553 |
| S100A10 | S100 calcium binding protein A10 | -0.0263644 |
| SETD5 | SET domain containing 5 | -0.0261087 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0252235 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0251976 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0251038 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0250347 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0241362 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0234173 |
| KIFAP3 | kinesin-associated protein 3 | -0.0233968 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0227055 |
| VMP1 | vacuole membrane protein 1 | -0.0226412 |
| DENND5A | DENN/MADD domain containing 5A | -0.0223123 |
| USP34 | ubiquitin specific peptidase 34 | -0.022141 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.022122 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0218713 |
| PTMA | prothymosin, alpha | -0.0214994 |
| GLG1 | golgi glycoprotein 1 | -0.0213963 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0213256 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0207929 |
| TXNIP | thioredoxin interacting protein | -0.0205962 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | -0.0204734 |
| SLC22A23 | solute carrier family 22, member 23 | -0.02046 |
| CLU | clusterin | -0.0203595 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0199571 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0198825 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.019829 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0197114 |
| PRKD3 | protein kinase D3 | -0.0196004 |
| WTAP | Wilms tumor 1 associated protein | -0.0193486 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.019038 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0189956 |
| RPS27A | ribosomal protein S27a | -0.0189867 |
| SDC4 | syndecan 4 | -0.01873 |
| HIP1 | huntingtin interacting protein 1 | -0.0187038 |
| PCBP2 | poly(rC) binding protein 2 | -0.0186255 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.018261 |
| TMOD1 | tropomodulin 1 | -0.0179753 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0179576 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0178829 |
| CLIC4 | chloride intracellular channel 4 | -0.0177678 |
| MAP4 | microtubule-associated protein 4 | -0.0176894 |
| FUS | FUS RNA binding protein | -0.0176247 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0173898 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0173892 |
| TAOK1 | TAO kinase 1 | -0.0172676 |
| COPA | coatomer protein complex, subunit alpha | -0.0172504 |
| MMP12 | matrix metallopeptidase 12 | -0.0171923 |
| XPO1 | exportin 1 | -0.0171686 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0170809 |
| METTL15 | methyltransferase like 15 | -0.0170783 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0169577 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0168589 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0168139 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0167158 |
| KLHL24 | kelch-like family member 24 | -0.0165374 |
| WDFY1 | WD repeat and FYVE domain containing 1 | -0.0162308 |
| MYO9B | myosin IXB | -0.0160923 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0160634 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0160135 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0158386 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0157497 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0157423 |
| MTSS1 | metastasis suppressor 1 | -0.0157174 |
| FRMD5 | FERM domain containing 5 | -0.0156633 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | -0.0155024 |
| GLIS3 | GLIS family zinc finger 3 | -0.0154234 |
