| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NVP-BHG712 perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the NVP-BHG712_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.130543 |
| TMSB10 | thymosin beta 10 | 0.129679 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.111186 |
| RPS19 | ribosomal protein S19 | 0.107588 |
| FTL | ferritin, light polypeptide | 0.100003 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0901449 |
| KYNU | kynureninase | 0.0850085 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0849761 |
| STC1 | stanniocalcin 1 | 0.0643038 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0604531 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.0582766 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0579473 |
| RPL18 | ribosomal protein L18 | 0.055009 |
| RPL23 | ribosomal protein L23 | 0.0546204 |
| RPS17 | ribosomal protein S17 | 0.0535776 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0532727 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0529666 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0520795 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0512762 |
| RPL37A | ribosomal protein L37a | 0.0500853 |
| LDHA | lactate dehydrogenase A | 0.0491845 |
| NDRG1 | N-myc downstream regulated 1 | 0.0482515 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0455353 |
| RPS4X | ribosomal protein S4, X-linked | 0.045187 |
| MT1X | metallothionein 1X | 0.0448993 |
| RHCG | Rh family, C glycoprotein | 0.043384 |
| RPL19 | ribosomal protein L19 | 0.043186 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.042726 |
| RPS3 | ribosomal protein S3 | 0.0425218 |
| RPL12 | ribosomal protein L12 | 0.0421713 |
| PRRC2C | proline-rich coiled-coil 2C | 0.041704 |
| TXNRD1 | thioredoxin reductase 1 | 0.0405103 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0398745 |
| PFN1 | profilin 1 | 0.0395882 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0395337 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0388979 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0387635 |
| B2M | beta-2-microglobulin | 0.0375232 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0367294 |
| EGFR | epidermal growth factor receptor | 0.0364819 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0363991 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0362449 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0361632 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0355532 |
| TPI1 | triosephosphate isomerase 1 | 0.035495 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.035179 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0349335 |
| MCL1 | myeloid cell leukemia 1 | 0.034469 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.03427 |
| RPS13 | ribosomal protein S13 | 0.033911 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.0335654 |
| CANX | calnexin | 0.0333799 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0330146 |
| PKM | pyruvate kinase, muscle | 0.0324499 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.032167 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0320758 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0312956 |
| RNF145 | ring finger protein 145 | 0.0301983 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0295705 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0293573 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0293307 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0289944 |
| PARD3 | par-3 family cell polarity regulator | 0.0289456 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.0288858 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0287397 |
| RPL27 | ribosomal protein L27 | 0.0286537 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.027902 |
| RPL26 | ribosomal protein L26 | 0.0272754 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0270621 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0270481 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0269259 |
| RPL35 | ribosomal protein L35 | 0.0262611 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0259125 |
| RACK1 | receptor for activated C kinase 1 | 0.0258085 |
| HELZ | helicase with zinc finger | 0.0257362 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0257185 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0256844 |
| RPL7 | ribosomal protein L7 | 0.0256167 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.025566 |
| PCBP2 | poly(rC) binding protein 2 | 0.0251365 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0244842 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0241366 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0239561 |
| RNF213 | ring finger protein 213 | 0.0237851 |
| SON | SON DNA binding protein | 0.0237508 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0237269 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0237143 |
| CENPF | centromere protein F, 350/400kDa | 0.0233884 |
| MSN | moesin | 0.0229862 |
| RPS8 | ribosomal protein S8 | 0.0228859 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0228651 |
| CLTC | clathrin, heavy chain (Hc) | 0.0228459 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0225168 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0223713 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0222893 |
| VMP1 | vacuole membrane protein 1 | 0.022143 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0220987 |
| MYOF | myoferlin | 0.0219608 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.02184 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0218234 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.170315 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.072086 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0704526 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0579856 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0528105 |
| CA12 | carbonic anhydrase XII | -0.0517253 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0470203 |
| VIM | vimentin | -0.0457304 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0434538 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0427974 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0426626 |
| SMYD3 | SET and MYND domain containing 3 | -0.0423313 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0389728 |
| CCDC88A | coiled-coil domain containing 88A | -0.0378869 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | -0.0372407 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0363795 |
| ANXA2 | annexin A2 | -0.0359548 |
| MYO1E | myosin IE | -0.0352809 |
| VCL | vinculin | -0.0351362 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0348913 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0345867 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0343313 |
| PDE10A | phosphodiesterase 10A | -0.0342451 |
| PRKCA | protein kinase C, alpha | -0.0326895 |
| S100A10 | S100 calcium binding protein A10 | -0.0326089 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0324685 |
| CD44 | CD44 molecule (Indian blood group) | -0.0315891 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0308445 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0303228 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0296694 |
| JMJD1C | jumonji domain containing 1C | -0.029143 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0290721 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0286715 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0280069 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0276735 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0270127 |
| RIN2 | Ras and Rab interactor 2 | -0.0269623 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.026703 |
| RPS16 | ribosomal protein S16 | -0.0266149 |
| EHBP1 | EH domain binding protein 1 | -0.0265053 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0263197 |
| RTN4 | reticulon 4 | -0.0261747 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0261317 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0258848 |
| EFNA5 | ephrin-A5 | -0.0252437 |
| ACTN4 | actinin, alpha 4 | -0.0247969 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0247864 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0247043 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0236146 |
| OSMR | oncostatin M receptor | -0.0234441 |
| BCL2L1 | BCL2-like 1 | -0.0233255 |
| HPCAL1 | hippocalcin-like 1 | -0.0228796 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0228008 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0221868 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0221335 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0221025 |
| BPTF | bromodomain PHD finger transcription factor | -0.0210867 |
| EXOC6B | exocyst complex component 6B | -0.0206391 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0205979 |
| NAV2 | neuron navigator 2 | -0.0204461 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.02008 |
| CEP112 | centrosomal protein 112kDa | -0.0200162 |
| SSH2 | slingshot protein phosphatase 2 | -0.0198152 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.0197407 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0196685 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0196324 |
| SEPTIN9 | septin 9 | -0.0196072 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0194843 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0193924 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0193489 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0193347 |
| PYGL | phosphorylase, glycogen, liver | -0.0192046 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0189568 |
| GOLGB1 | golgin B1 | -0.0188225 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0185343 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0184933 |
| ITGB5 | integrin, beta 5 | -0.0184554 |
| AHNAK | AHNAK nucleoprotein | -0.0184032 |
| FBXO11 | F-box protein 11 | -0.0183893 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0183368 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0182057 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0182038 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | -0.0181838 |
| ANKRD27 | ankyrin repeat domain 27 (VPS9 domain) | -0.0180152 |
| GRAMD1A | GRAM domain containing 1A | -0.017937 |
| ST6GAL2 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 | -0.0178893 |
| GPATCH8 | G patch domain containing 8 | -0.0178587 |
| ITSN2 | intersectin 2 | -0.0177784 |
| MYO9A | myosin IXA | -0.0174176 |
| RAB10 | RAB10, member RAS oncogene family | -0.0172943 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.017194 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0171008 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0170774 |
| RAD51B | RAD51 paralog B | -0.0170765 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0170046 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0169701 |
| MCU | mitochondrial calcium uniporter | -0.0169326 |
| EGR1 | early growth response 1 | -0.016928 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | -0.0169149 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | -0.0169109 |
