| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NVP-BHG712 perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the NVP-BHG712_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.102852 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0829591 |
| PLEC | plectin | 0.0821662 |
| LAMB3 | laminin, beta 3 | 0.0664197 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0623746 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0561598 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0537538 |
| NDRG1 | N-myc downstream regulated 1 | 0.0534226 |
| EZR | ezrin | 0.0514488 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0508247 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0500236 |
| FTL | ferritin, light polypeptide | 0.0495439 |
| FMNL2 | formin-like 2 | 0.0465506 |
| TPM3 | tropomyosin 3 | 0.0455539 |
| MCL1 | myeloid cell leukemia 1 | 0.0444118 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0420514 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0393509 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0350757 |
| KLK10 | kallikrein-related peptidase 10 | 0.0336881 |
| DSPP | dentin sialophosphoprotein | 0.033555 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0327823 |
| OPTN | optineurin | 0.031308 |
| ANXA2 | annexin A2 | 0.0311836 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.031163 |
| RPS3 | ribosomal protein S3 | 0.030576 |
| HMGA2 | high mobility group AT-hook 2 | 0.0300379 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0299534 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.029754 |
| DIAPH1 | diaphanous-related formin 1 | 0.0295252 |
| VIM | vimentin | 0.0287273 |
| RACK1 | receptor for activated C kinase 1 | 0.0276431 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0275074 |
| POTEF | POTE ankyrin domain family, member F | 0.0268085 |
| RPS12 | ribosomal protein S12 | 0.0263649 |
| TGM2 | transglutaminase 2 | 0.0262673 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0243139 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0237409 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0234014 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0230843 |
| SET | SET nuclear proto-oncogene | 0.0228416 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0228136 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0228131 |
| RPL37A | ribosomal protein L37a | 0.0228079 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0224011 |
| SEPTIN9 | septin 9 | 0.0220761 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0214008 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0212932 |
| CAPRIN2 | caprin family member 2 | 0.0207898 |
| RPS8 | ribosomal protein S8 | 0.0203924 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0199437 |
| IGF2 | insulin-like growth factor 2 | 0.0192284 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.0191277 |
| FLNA | filamin A, alpha | 0.0190945 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0185583 |
| B2M | beta-2-microglobulin | 0.0184225 |
| HDAC9 | histone deacetylase 9 | 0.0183102 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0181886 |
| RPS2 | ribosomal protein S2 | 0.0180662 |
| RPS27 | ribosomal protein S27 | 0.0180399 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0180253 |
| FAM13A | family with sequence similarity 13, member A | 0.0179914 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0175835 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0175603 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.017556 |
| PCBP2 | poly(rC) binding protein 2 | 0.017533 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0175191 |
| INTS6 | integrator complex subunit 6 | 0.0171926 |
| RPL35A | ribosomal protein L35a | 0.017125 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0168098 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0168049 |
| SMYD3 | SET and MYND domain containing 3 | 0.0164374 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0162405 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0161658 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0159858 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0159119 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0158764 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0157934 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0156273 |
| CTBP2 | C-terminal binding protein 2 | 0.0155988 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0153013 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0151918 |
| GTDC1 | glycosyltransferase-like domain containing 1 | 0.015025 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.014677 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0146067 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0145717 |
| VEGFA | vascular endothelial growth factor A | 0.0144947 |
| RAI14 | retinoic acid induced 14 | 0.0144939 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0143875 |
| SULF2 | sulfatase 2 | 0.0143602 |
| RPL3 | ribosomal protein L3 | 0.0142243 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0142171 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0141423 |
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.0140954 |
| ZNF638 | zinc finger protein 638 | 0.01403 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0139278 |
| RBM19 | RNA binding motif protein 19 | 0.0137908 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0136208 |
| PKM | pyruvate kinase, muscle | 0.0135724 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0135695 |
| BMP6 | bone morphogenetic protein 6 | 0.0135466 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.137368 |
| TMSB10 | thymosin beta 10 | -0.13619 |
| LMO7 | LIM domain 7 | -0.128294 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.120685 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.120435 |
| TXNRD1 | thioredoxin reductase 1 | -0.111709 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.106069 |
| S100A10 | S100 calcium binding protein A10 | -0.0936796 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0844106 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0679881 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0603252 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.0601165 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0594407 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0549121 |
| FLNB | filamin B, beta | -0.0527402 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0464336 |
| UBC | ubiquitin C | -0.0456681 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0449704 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0448297 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0446742 |
| AHNAK | AHNAK nucleoprotein | -0.044476 |
| NPSR1 | neuropeptide S receptor 1 | -0.0443539 |
| PTMA | prothymosin, alpha | -0.0441903 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0438305 |
| DSG2 | desmoglein 2 | -0.0423908 |
| CD2AP | CD2-associated protein | -0.0419603 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0419204 |
| EGFR | epidermal growth factor receptor | -0.0417498 |
| KLF6 | Kruppel-like factor 6 | -0.0407716 |
| EMP1 | epithelial membrane protein 1 | -0.039687 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0393518 |
| ARHGAP42 | Rho GTPase activating protein 42 | -0.0367235 |
| JMJD1C | jumonji domain containing 1C | -0.0364081 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0358316 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0353194 |
| PRSS3 | protease, serine, 3 | -0.035083 |
| PLAUR | plasminogen activator, urokinase receptor | -0.034486 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0344059 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0340532 |
| RPLP2 | ribosomal protein, large, P2 | -0.033498 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0326673 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0323293 |
| S100A4 | S100 calcium binding protein A4 | -0.0323238 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0315689 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0313463 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0310139 |
| RPS23 | ribosomal protein S23 | -0.030207 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0299319 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0297569 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0294957 |
| ATG12 | autophagy related 12 | -0.0289627 |
| FOXO1 | forkhead box O1 | -0.0283532 |
| SDC4 | syndecan 4 | -0.0281741 |
| WASF2 | WAS protein family, member 2 | -0.0280319 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0280277 |
| RESF1 | retroelement silencing factor 1 | -0.0278644 |
| IER3 | immediate early response 3 | -0.0269002 |
| CAB39 | calcium binding protein 39 | -0.0268816 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0265779 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0263726 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0261165 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0259219 |
| H1-0 | H1.0 linker histone | -0.025885 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0257783 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0251011 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0249513 |
| RASAL2 | RAS protein activator like 2 | -0.024899 |
| RIOK3 | RIO kinase 3 | -0.0248736 |
| RPS24 | ribosomal protein S24 | -0.0246232 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0242754 |
| VCAN | versican | -0.0240249 |
| RRBP1 | ribosome binding protein 1 | -0.0239647 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0239478 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0239175 |
| PGK1 | phosphoglycerate kinase 1 | -0.0238988 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0238036 |
| TPM4 | tropomyosin 4 | -0.0237298 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0237112 |
| CDCP1 | CUB domain containing protein 1 | -0.0236458 |
| RPL8 | ribosomal protein L8 | -0.0230313 |
| SPAG9 | sperm associated antigen 9 | -0.0229596 |
| LAMC2 | laminin, gamma 2 | -0.0228006 |
| RPL12 | ribosomal protein L12 | -0.0226286 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0222892 |
| TMEM263 | transmembrane protein 263 | -0.0219447 |
| RHEB | Ras homolog enriched in brain | -0.0219291 |
| RPL32 | ribosomal protein L32 | -0.0218089 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0216 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0215729 |
| ASPH | aspartate beta-hydroxylase | -0.0207775 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0207344 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0207045 |
| STK39 | serine threonine kinase 39 | -0.0206794 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0206436 |
| SMNDC1 | survival motor neuron domain containing 1 | -0.0205343 |
| ANLN | anillin, actin binding protein | -0.0203502 |
| RPL36A | ribosomal protein L36a | -0.0203073 |
| CORO1C | coronin, actin binding protein, 1C | -0.0201824 |
| PARD6B | par-6 family cell polarity regulator beta | -0.020136 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.0197143 |
