| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NVP-BHG712 perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the NVP-BHG712_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.120527 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.116638 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0920306 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0907502 |
| RPS4X | ribosomal protein S4, X-linked | 0.0773389 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0731653 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0696657 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.066201 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0657979 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0643788 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0639484 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0593837 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0551203 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0549577 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0538847 |
| LDHA | lactate dehydrogenase A | 0.0491269 |
| TUBB | tubulin, beta class I | 0.0490009 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0485316 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.047738 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0476345 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0470302 |
| RIGI | RNA sensor RIG-I | 0.045884 |
| FLNA | filamin A, alpha | 0.04534 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0447658 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0440653 |
| DENND1A | DENN/MADD domain containing 1A | 0.0436041 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.040609 |
| ZNF608 | zinc finger protein 608 | 0.039282 |
| ACTG1 | actin gamma 1 | 0.0387179 |
| ATP11A | ATPase, class VI, type 11A | 0.0386442 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0383228 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0381828 |
| KPNB1 | karyopherin (importin) beta 1 | 0.036907 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0368362 |
| CTBP2 | C-terminal binding protein 2 | 0.0363458 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0355159 |
| RPLP0 | ribosomal protein, large, P0 | 0.0353422 |
| RPL3 | ribosomal protein L3 | 0.0351065 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0349511 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0348067 |
| RPLP1 | ribosomal protein, large, P1 | 0.0347185 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.0346587 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.0341474 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0336372 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.0336081 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0332778 |
| HDLBP | high density lipoprotein binding protein | 0.033066 |
| CENPF | centromere protein F, 350/400kDa | 0.0328765 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0328679 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0326447 |
| TMSB10 | thymosin beta 10 | 0.0324371 |
| RPLP2 | ribosomal protein, large, P2 | 0.0323177 |
| GNAS | GNAS complex locus | 0.0322297 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.0318439 |
| TPI1 | triosephosphate isomerase 1 | 0.0317829 |
| WLS | wntless Wnt ligand secretion mediator | 0.0314223 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0312888 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.030984 |
| RRM2 | ribonucleotide reductase M2 | 0.0308686 |
| RPS21 | ribosomal protein S21 | 0.0306776 |
| CANX | calnexin | 0.0302953 |
| RHOA | ras homolog family member A | 0.0301763 |
| RNF213 | ring finger protein 213 | 0.0299489 |
| COL5A2 | collagen, type V, alpha 2 | 0.029253 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0290904 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0288231 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0287006 |
| ENO1 | enolase 1, (alpha) | 0.0285745 |
| TOX | thymocyte selection-associated high mobility group box | 0.0285362 |
| YBX1 | Y box binding protein 1 | 0.0284086 |
| CNN2 | calponin 2 | 0.0283069 |
| EXOC4 | exocyst complex component 4 | 0.0281131 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0276956 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0276478 |
| SKI | SKI proto-oncogene | 0.0276277 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0271803 |
| DEK | DEK proto-oncogene | 0.0270834 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0270371 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0266646 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | 0.0266343 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0266319 |
| RPL19 | ribosomal protein L19 | 0.0265634 |
| CREBBP | CREB binding protein | 0.0265607 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0262871 |
| UBAP2 | ubiquitin associated protein 2 | 0.0262009 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0260529 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0260199 |
| RPS11 | ribosomal protein S11 | 0.0260181 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0259992 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0256958 |
| RPL23 | ribosomal protein L23 | 0.0256594 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0252313 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0247543 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.0245336 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0243449 |
| CUX1 | cut-like homeobox 1 | 0.024195 |
| RPS16 | ribosomal protein S16 | 0.0240628 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.0240532 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0240019 |
| TENM3 | teneurin transmembrane protein 3 | 0.0239337 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPAS3 | neuronal PAS domain protein 3 | -0.113137 |
| CADM2 | cell adhesion molecule 2 | -0.0802281 |
| ZNF292 | zinc finger protein 292 | -0.0697728 |
| NFIA | nuclear factor I/A | -0.0539869 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0516041 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0508996 |
| NKTR | natural killer cell triggering receptor | -0.0474857 |
| GRID2 | glutamate receptor, ionotropic, delta 2 | -0.0446055 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0409333 |
| FNBP1L | formin binding protein 1-like | -0.0409245 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0397928 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | -0.0393114 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | -0.0392315 |
| NUP58 | nucleoporin 58 | -0.0389347 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0384601 |
| DST | dystonin | -0.0380637 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0378543 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0374714 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | -0.0373051 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0372259 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0366591 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0365352 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0360488 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0360223 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0359075 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0358793 |
| SETD5 | SET domain containing 5 | -0.0346865 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0330891 |
| GOLGA4 | golgin A4 | -0.03294 |
| CEP95 | centrosomal protein 95kDa | -0.0329397 |
| RTN4 | reticulon 4 | -0.0323679 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0323313 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0319823 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0315434 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0312384 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0309984 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.030806 |
| CCNL1 | cyclin L1 | -0.0297304 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0295204 |
| QKI | QKI, KH domain containing, RNA binding | -0.0289005 |
| ANKRD36 | ankyrin repeat domain 36 | -0.028812 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0285308 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0281727 |
| HELZ | helicase with zinc finger | -0.0281248 |
| ZSWIM5 | zinc finger, SWIM-type containing 5 | -0.0281227 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0280359 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0272636 |
| KIF13A | kinesin family member 13A | -0.0268623 |
| SBF2 | SET binding factor 2 | -0.0267902 |
| VGLL4 | vestigial-like family member 4 | -0.0265338 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0265089 |
| MYO9A | myosin IXA | -0.0264437 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0264111 |
| RLF | rearranged L-myc fusion | -0.0262147 |
| ARFGEF3 | ARFGEF family member 3 | -0.0259516 |
| H1-0 | H1.0 linker histone | -0.0259283 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0259224 |
| EFNA5 | ephrin-A5 | -0.0257166 |
| NOP58 | NOP58 ribonucleoprotein | -0.0256521 |
| TET2 | tet methylcytosine dioxygenase 2 | -0.0254537 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0250855 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | -0.0247155 |
| ZNF326 | zinc finger protein 326 | -0.0245451 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0243399 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | -0.0242228 |
| EPC1 | enhancer of polycomb homolog 1 (Drosophila) | -0.0241576 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0240865 |
| TPD52 | tumor protein D52 | -0.0238673 |
| RPS12 | ribosomal protein S12 | -0.0237746 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0237408 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0236901 |
| INSIG2 | insulin induced gene 2 | -0.0235192 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.0232136 |
| PDS5B | PDS5 cohesin associated factor B | -0.0232091 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0231217 |
| PRELID2 | PRELI domain containing 2 | -0.0230691 |
| MATR3 | matrin 3 | -0.0228235 |
| RPS2 | ribosomal protein S2 | -0.0227386 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.022679 |
| MYO6 | myosin VI | -0.0224074 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0222064 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0221978 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0221963 |
| FBXO11 | F-box protein 11 | -0.0220279 |
| NGLY1 | N-glycanase 1 | -0.0220141 |
| NEK7 | NIMA-related kinase 7 | -0.0219143 |
| GPHN | gephyrin | -0.0218424 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0218 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0217893 |
| SEPTIN7 | septin 7 | -0.0217118 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | -0.0216821 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0214676 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0214423 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0213791 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0212681 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0212293 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0209596 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0207377 |
| MYO1D | myosin ID | -0.0203819 |
| SMYD3 | SET and MYND domain containing 3 | -0.02006 |
